• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3447-3450
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• 2015

Objective: To explore the sensitivity of gastric cancer cells to chemotherapy drugs in elderly patients and its correlation with cyclooxygenase-2 (COX-2) expression in cancer tissue. Materials and Methods: Forty-three elderly patients with gastric cancer (observation group) and 31 young patients with gastrointestinal tumors (control group) who were all diagnosed by pathology and underwent surgery in the 89th Hospital of Chinese People's Liberation Army were selected. Drug sensitivity testing of tumor cells in primary culture was carried out in both groups using a methyl thiazolyl tetrazolium (MTT) method, and the expression of COX-2 and the factors related to multi-drug resistance (MDR) in cancer tissue were assessed by immunohistochemistry. Results: The inhibition rates (IR) of vincristine (VCR), 5-fluorouracil (5-FU), oxaliplatin (L-OHP), mitomycin (MMC) and epirubicin (eADM) on tumor cells in the observation group were dramatically lower than in the control group, with statistical significance (P<0.05 or P<0.01). The positive rates of COX-2, glutathione s-transferase-${\pi}$ (GST-${\pi}$) and P glycoprotein (P-gp) expression in cancer tissue in the observation group were all higher than in control group (P<0.05), while that of DNA topoisomerase $II{\alpha}$ ($TopoII{\alpha}$) expression lower than in the control group (P<0.01). In the observation group, COX-2 expression in cancer tissue had a significantly-positive correlation with GST-${\pi}$ and P-gp (r=0.855, P=0.000; r=0.240, P=0.026), but a negative correlation with $TopoII{\alpha}$ (r=-0.328, P=0.002). In the control group, COX-2 expression in cancer tissue was only correlated with P-gp positively (r=0.320, P=0.011). Bivariate correlation analysis displayed that COX-2 expression in cancer tissue in the observation group had a significantly-negative correlation with the IRs of 5-FU, L-OHP, paclitaxel (PTX) and eADM in tumor cells (r=-0.723, P=0.000; r=-0.570, P=0.000; r=-0.919, P=0.000; r=-0.781, P=0.000), but with hydroxycamptothecine (HCPT), VCR and 5-FU in the control group (r=-0.915, P=0.000; r=-0.890, P=0.000; r=-0.949, P=0.000). Conclusions: Gastric cancer cells in elderly patients feature stronger MDR, which may be related to high COX-2 expression.

• Solar Energy
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• v.15 no.3
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• pp.75-90
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• 1995

This paper is concerned about alternative refrigerants for HCFC22 used in room air conditioners and heat pumps. Computer simulation of residential air conditioners using refrigerant mixtures is carried out. Following refrigerants are selected as the pure refrigerants constituting the mixtures studied: R32, R124, R125, R134, R134a, R143a and R152a. Simulation results are presented fur the following mixtures: R32/R134a, R32/R152a, R32/R134, R32/R124, R143a/R134a, R143a/R152a, R143a/R124, R125/R134a, R125/R152a, R125/R124, R32/R152a/R134a, R32/R152a/R134, R32/R152a/R124. The best fluid is found to be the ternary mixture of R32/R152a/R124. For that mixture, the coefficient of performance(COP) and volumetric capacity for refrigeration(VCR) are 13.7% larger and 23% smaller than the respective values for HCFC22. R32/R124 mixture is the best binary fluid pair whose COP and VCR are 13.4% larger and 9.6% smaller than those for HCFC22.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.4C
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• pp.413-423
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• 2003

The CMA algorithmis most widely investigated blind algorithm and the most widely used one in practice. But, since nonlinear CM cost function have not closed form solution about the optimum weight. There have been difficultiesto analyze the CMA equalizer's theoretical performance. Recently, Zeng presents the notable theoretical resultabout the MSE of CM-minimizing estimators for the FIR linear channel in the presence of AWGN. Through this method, It wouldbe possible to campare the theoretical performance between CMA and Wiener equalizer in terms of MSE. In this paper, based on Zeng's method, we first calculate the theoretical MSE bound of CMA equalizer in partial response channel which is widely used in HDD, digital VCR such as high-density digital recording.playback systems. We confirmedthis result withthe computer simulation. Except this, we also performedthe theoretical and simulation analysis about the modified CMA equalizer, which was proposed to improve the performance of CMA equalizer in partial response channel. Finally, we compare and evaluate the performance analysis results between CMA and Modified CMA equalizer.

• Journal of Advanced Marine Engineering and Technology
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• v.30 no.1
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• pp.42-49
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• 2006

In this research. the diesel cycle was thermodynamically interpreted to evaluate the possibility of high efficiency by converting diesel engines to the high expansion diesel cycle, and general cycle features were analyzed after comparing these two cycles. Based on these analyses. an experimental single cylinder a long stroke with high expansion-diesel engine. of which S/B ratio was more than 3, was manufactured. After evaluating the base engine through basic experiments, a diesel engine was converted into the high expansion diesel engine by establish VCR device and VVT system Accordingly, the high expansion diesel cycle can be implemented when the quantity of intake air is compensated by supercharge and the effective compression ratio is maintained at its initial level through the reduction of the clearance volume. In this case, heat efficiency increased by $5.0\%$ at the same expansion-compression ratio when the apparent compression ratio was 20 and the fuel cut off ratio was 2. As explained above, when the atkinson cycle was used for diesel cycle, heat efficiency was improved. In order to realize high expansion through retarding the intake value closing time, the engine needs to be equipped with variable valve timing equipment, variable compression ratio equipment and supercharged pressure equipment. Then a high expansion diesel cycle engine is realized.

• Proceedings of the KIEE Conference
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• 2008.10b
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• pp.310-311
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• 2008

본 논문의 목표는 개인용 리치미디어 플레이어에 대한 연구이다. 개인용 리치미디어 플레이어는 아날로그 지상파, 케이블 방송, DVD VCR등과 같은 미디어로부터 아날로그 컨텐츠를 받아 H.264 Encoder를 상용하여 디지털화하여 유무선 인터넷을 통해 개인에게 직접 재전송 해 주는 플랫폼이다. 전 세계적으로 아날로그 방송을 디지털 방송으로 전환하고 있으나, 아날로그 방송을 시청하는 사람들은 상당히 많다. 대부분의 시청자들은 집에서 TV를 통해 프로그램을 시청하고 있다. 광대역 인터넷이 일반화 되면서 많은 사람들이 인터넷상에서 UCC나 VOD서비스 같은 멀티미디어 서비스를 이용하고있다. 하지만, 이러한 서비스들은 실시간으로 방송되는 프로그램을 서비스해주지는 못하고있다. 본 논문에서 개발한 개인형 리치미디어 플레이어는 실시간 방송 프로그램을 H.264로 인코딩하여 시청자가 인터넷에 접속할 수 있는 곳이면 어디든지 인터넷상으로 방송 프로그램은 즐길 수 있다. 본 논문에서 개발한 플랫폼은 ARM CORE와 H.264 Encoder를 사용하여 실시간으로 방송 컨텐츠를 인코딩하여 RTP, RTSP Protocol을 이용하여 유무선으로 전송하게 된다. 운영체제는 uClinux 26이고 Streaming Server는 실시간으로 네트워크 상황을 인지하여 다이나믹하게 전송 레이트를 조절함으로써 QoS를 구현하고 있다.

• Toxicological Research
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• v.17 no.2
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• pp.151-157
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• 2001

Neutropenia is a major dose-limiting side effect of cancer chemotherapy. The therapeutic effect of HM 10411 was examined on neutropenia caused by anticancer agents. Neutropenia in normal ICR mice was induced by a single combined intraperitoneal injection of 130 mg/kg of cyclophosphamide (CPA). 4.5 mg/kg of doxorubicin (DXR). and 1 mg/kg of vincristine (VCR) on day O. Neutropenia in tumor-bearing mice was made by a single intraperitoneal injection of 200 mg/kg of cyclophosphamide (CPA) into BALB/c mice bearing Colon 26 adenocarcinoma at 7 day after tumor implantation. HM 10411 or filgrastim (100 $\mu\textrm{g}$/kg/day) was subcutaneously administered for 5 consecutive days starting 1 day after injection of anticancer agents in order to stimulate neutrophil production. Injection of HM 10411 accelerated the recovery from these anticancer drug-induced neutropenia. In normal and tumor-bearing mice. neutrophil production efficacy of HM 10411 was similar than that of filgrastim. These results suggest that HM 10411 could be useful in the clinical treatment for neutropenia induced by anticancer agents.

• The Journal of the Korea Contents Association
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• v.13 no.6
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• pp.55-66
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• 2013

In these days, small devices like smartphones, TV, and projectors are popular, and they are being developed rapidly. The projector is being used in cinema and exhibition because it makes a big screen. This feature makes new expression named projection-mapping in art world. Projection-mapping is being utilized extensively in stages of performances, and it use variety of shape's screens. But projection-mapping has limitation in space. So in this paper, we propose new performance system for projection-mapping and it make possible to overcome many difficulties. Also, we discuss the result of using the system in actual performance. We hope to develop the utilization of projection-mapping in performance.

• Proceedings of the Korea Contents Association Conference
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• 2007.11a
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• pp.837-841
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• 2007

최근 영상을 중심으로 여러 형태의 정보를 결합하여 저장하거나 전송하는 멀티미디어가 많은 관심을 받고 있다. 현재 카메라와 관련된 동영상 캡처기술은 Motion JPEG이 주류를 이루고 있으며, 텔레비전, DMB 등의 방송 분야 및 DVD, VCR 분야에서는 MPEG-2, MPEG-4, H.264 및 WMV9 등의 압축 코덱이 채용되고 사용되고 있다. 그러나 이러한 다양한 영상 표준방식은 디코딩시 호환성 문제가 발생하게 되고 이에 따라 통합 코덱 연구가 필요하다. 이에 본 논문은 일반적 스텝 양자화외에 데드존 양자화를 사용하고 "$4{\times}4$", "$4{\times}8$", "$8{\times}4$", "$8{\times}8$"의 다양한 블록크기의 변환을 지원하는 VC-1을 기반으로 한 ITIQ C언어를 통해 시뮬레이션하고 최적화된 결과를 VHDL로 구현하여 향후 통합코덱 연구에 응용 가능하도록 연구 및 분석평가 하였다. 설계결과 4:2:0의 YCbCr포맷의 최초 $16{\times}16$블록을 복원하는데 483~510클록이 소요되었고 Xilinx XCVPC100 FF1696-6 환경에서 93,128개의 게이트 수와 71.469MHz의 동작속도를 나타내었다. 이는 640*480 크기의 컬러영상을 디코딩 하는데 프레임 당 최대 0.0074초가 소요됨을 의미하며 초당 30프레임의 영상에서도 0.222초면 디코딩이 가능한 결과이다.

• Journal of Korean Home Economics Education Association
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• v.15 no.1
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• pp.15-32
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• 2003

This study examined teacher perception of the instructional method. activities and material in terms of class quality enhancement. Also this study established instructional method. activities and material application Per 7th Practical Arts Education Course guidance domain. and type identification of the instructional method and activities unique to the Practical arts curriculum. Conclusions : 1. Teachers consider the instructional method and material beneficial. However in the item relevant to application of diverse instructional methods Per specific teaching objective and educational content in the actual classroom. the highest percentage responding. ‘relatively yes’ (39.7%) . balanced out with those answering. ‘no’(37.7%) 2. In linking the instructional method and material to secondary school home economics education, teachers experienced difficulty in teaching only the clothing education domain . 3. In each guidance domain, lecture method, problem-solving learning. cooperative learning. home project learning and functional learning were surveyed for instructional method suitability. Notably, home project learning was identified as a significant instructional method. This result begs in-dept analysis as home project learning may be utilized as a tool to compensate for the absence of practical educational objective condition fulfillment and to substitute for teachers unable to Provide such functional guidance in class. 4. In each guidance domain. role-playing. debate/discussion. case study research, practical exercise and activity reporting were rated as essential teaching ㆍ learning activities. 5. In each guidance domain.‘VCR’, ‘CD-ROM’ and ‘Web media’ were identified as suitable instructional materials .

• Journal of ILASS-Korea
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• v.2 no.4
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• pp.15-21
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• 1997

In a gasoline engine with port injection system, the fuel behavior in the intake port has significant influence on the HC emission and the precise A/F control. That is to say, it is inevitable that the injection direction and behavior of fuel injected in the intake port have an effect on the generation of unburned HC within a cylinder. In this paper, we visualized fuel behavior in the intake port using micro CCD camera synchronized with the stroboscope and investigated the fuel-film characteristics formed at the wall of intake port by processing image captured with VCR in the transparent intake port made of acryl. Using these measuring methods, it was found that fuel behavior and the formation of fuel-film in the intake port could be evaluated qualitatively. And results obtained by these methods show that 2-spray injector minimizes the fuel-film formed in the intake port of a DOHC gasoline engine.