• Title/Summary/Keyword: Uterine cervix carcinoma

Search Result 110, Processing Time 0.033 seconds

MR Imaging of Uterine Malignant Mixed M$\ddot{u}$llerian Tumor: Comparison with Endometrial Carcinoma (자궁의 악성혼합뮬러리안 종양의 자기공명영상: 자궁내막암과의 비교)

  • Cho, Jae-Ho;Kim, Jeen-Woo;Chang, Jay-Chun;Park, Bok-Hwan;Kim, Jung-Sik
    • Journal of Yeungnam Medical Science
    • /
    • v.16 no.2
    • /
    • pp.296-301
    • /
    • 1999
  • Background: Generally, it is difficult to differentiate uterine malignant mixed M$\ddot{u}$ llerian tumor(MMMT) from endometrial carcinom in radiological and clinical aspects. Our purpose is to investigate MR findings that distinguishes MMMT from endometrial carcinoma. Materials and Methods: We retrogradely evaluated the magnetic resonance imaging findings of pathologically proven 5 cases of malignant mixed M$\ddot{u}$llerian tumor(MMMT) and 14 endometrial carcinomas to know the differential points of these two tumors originating in the endometrial cavity. The size of the mass, presence or absence of myometrial or uterine cervical invasion, growth pattern of the mass, signal intensity and degree and pattern of contrast enhancement were analyzed and compared. Results: The length of the long axis of the MMMT was 1.5-9.0cm(average, 5.7cm) but that of the endometrial carcinoma was 0.5-6.0cm(average, 2.5cm). Invasion of uterine cervix which was found in 3 MMMT cases, dilated the endometrial cavity and the lumen of the uterine cervix and showed the pattern of growing into the external os. Invasion of uterine cervix was found in only one case of endometrial carcinoma. The presence or absence of myometrial invasion, the signal intensity and homogeneity on T1- and T2-weighted images, and the degree and patterns of contrast enhancement showed no significant difference. Conclusion: Any specific finding to differentiate MMMT from endometrial carcinoma was not ascertained. However, MMMT can be suspected if the size of the endometrial mass is greater than 5cm and if the mass dilates the enocervical canal and invades the uterine cervix.

  • PDF

A Study on Dose Calculation in Intracavitary Radiotherapy of the Carcinoma of the Uterine Cervix with TAO Applicator (TAO Applicator를 이용한 자궁경암 강내조사시의 선양계산에 관한 고찰)

  • Kim, Chul-Soo;Kim, Jung-Jin
    • Radiation Oncology Journal
    • /
    • v.2 no.1
    • /
    • pp.101-106
    • /
    • 1984
  • Various methods are available for determination of exposure time in intracavitary radiotherapy of the carcinoma of the uterine cervix. To determine the accuracy of dose calculation with isodose curve for TAO applicator, comparison with results calculated by computer for radiotherapy treatment Planning was done in 24 procedures done in 12 consecutive patients with the carcinoma of the uterine cervix from May to December, 1983. The results are as follows: 1. The average dose rate Per hour of Point A was 87.70 rad, being 89.91 rad ana 85.49 rad in left and right, respectively. 2. The average percentage of dose rate of point A calculated by isodose curve method over that by computer was $101.28\%$ and the difference was less than $5\%$ in 17 Procedures and over $10\%$ in only 3 procedures. 3. The average percentage in case of point B was $108.67\%$. In conclusion, in most cases the difference was less than 200 rad for point A and less than 100 rad for point B during 2 courses of intracavitary radiotherapy. And so the dose rate calculation with isodose curve for TAO applicator is comparatively accurate.

  • PDF

Iliopelvic Lymphoscintigraphic Findings in Carcinoma of Uterine Cervix (자궁경부암 환자에서의 Lymphoscintigraphy 소견)

  • Lim, Sang-Moo;Hong, Sung-Woon;Park, Sang-Yun;Lee, Je-Ho;Lee, Eui-Don;Lee, Kyung-Hee;Park, Kee-Bok;Choi, Chang-Woon
    • The Korean Journal of Nuclear Medicine
    • /
    • v.24 no.2
    • /
    • pp.286-292
    • /
    • 1990
  • Iliopelvic lymphoscintigraphy was performed to visualize the changes of the lymphatic system using Technetium-99m antimony sulfide colloid in carcinoma of uterine cervix. There were no differences between various indices and clinical stages, but comparison with computed tomographic and postoperative findings, there was meaningful difference in index of decrease and increase, respectively. And lymphoscintigraphy showed by pass way of lymphatic channel in 42 cases (16%) and this suggested the presence of normal shunts of lymphatic channels. Iliopelvic lymphoscintigraphy may be useful for evaluation of lymphatic system in carcinoma of uterine cervix, expecially for screening method.

  • PDF

Radiotherapy of Para-Aortic Node Metastases in Carcinoma of the Uterine Cervix (자궁경부암에서 대동맥 임파절 전이의 치료)

  • Lee Jong Young;Suh Chang Ok;Seong Jin Sil;Kim Gwi Eon;John Juhn-Kyu
    • Radiation Oncology Journal
    • /
    • v.7 no.2
    • /
    • pp.259-267
    • /
    • 1989
  • Forty one patients with para-aortic node metastases from carcinoma of the uterine cervix treated with radiotherapy at Department of Radiation Oncology, Yonsei University, College of Medicine from January 1982 to December 1987 were retrospectively analyzed. Eleven patients were diagnosed at the time of diagnosis of carcinoma of the cervix (early diagnosis) and 30 patients were diagnosed during follow up period after definitive radiotherapy of primary site (late diagnosis). The most important factors affecting the survival in this study were time of diagnosis and dose of irradiation. Overall 5 year actuarial survival rate of 41 patients was $25.7\%$. Five year survival rate for early diagnosis was $60.3\%$, but late diagnosis was $16.9\%$. And survival rate for high dose (over 4000 cGy) radiation group and low dose radiation group were $42.2\%\;and\;8.9\%$ respectively The most leading cause of death was para-aortic node failure, so early diagnosis and maximum palliation with full dose radiotherapy (over 4000 cGy) is necessary to improve the survival and the quality of life.

  • PDF

Treatment of Early Glassy Cell Carcinoma of Uterine Cervix (초기 자궁경부 유리세포암의 치료)

  • Kim Ok-Bae;Kim Jin-Hee;Choi Tae-Jin
    • Radiation Oncology Journal
    • /
    • v.24 no.2
    • /
    • pp.123-127
    • /
    • 2006
  • Purpose: The purpose of this study was to investigate the clinical findings, treatment, and outcome of patients with glassy cell carcinoma of cervix. Materials and Methods: We reviewed all cases of glassy cell carcinoma of the uterine cervix confirmed and treated at the Dongsan Medical Center, Keimyung University, between January 1993 and December 2005. There were 7 cases with histopathologically confirmed gassy cell carcinoma. A tumor was diagnosed as glassy cell carcinoma if over 50% of the tumor cell type displayed glassy cell features. Six patients with stage IB had radical hysterectomy and bilateral pelvic node dissection, and 2 of them received adjuvant external pelvic irradiation with concurrent chemotherapy. Remaining one patient with stage IIA had curative concurrent chemoradiotherapy with external pelvic irradiation and brachytherapy. Results: There were 7 patients diagnosed as glassy cell carcinoma among the 3,745 (0.2%) patients of carcinoma of uterine cervix. The mean age of 7 patients was 44 years with range of 35 to 53 years of age. The most frequent symptom was vaginal bleeding (86%). By the punch biopsy undertaken before treatment of 7 cases, 2 only cases could diagnose as glassy cell carcinoma of uterine cervix, but remaining of them confirmed by surgical pathological examination. The mean follow up duration was 73 months with range of 13 to 150 months. All 7 patients were alive without disease after treatment. Conclusion: Glassy cell carcinoma of the uterine cervix is a distinct clinicopathologic entity that demonstrates an aggressive biologic behavior. However for early-stage disease, we may have more favorable clinical outcome with radical surgery followed by chemoradiothery.

Analysis of Pretreatment Prognostic Factors in Stage IIB Carcinoma of the Uterine Cervix (자궁경부암 IIB 병기에서의 치료전 예후 인자의 분석)

  • Shin, Kyung-Hwan;Ha, Sung-Whan;Yoo, Keun-Young
    • Radiation Oncology Journal
    • /
    • v.10 no.2
    • /
    • pp.227-236
    • /
    • 1992
  • From March 1979 through December 1986, 232 previously untreated patients with invasive carcinoma of the uterine cervix stage IIB were treated at the Department of Therapeutic Radiology, Seoul National University Hospital. The patients studied were staged according to the FIGO recommendations and the majority of patients were treated with external beam whole pelvis radiation and intracavitary radiation. Pretreatment parameters, including physical examination findings, blood parameters, prior medical illnesses, histology and abdomino-pelvic CT findings were studied, employing univariate and multivariate analyses to identify the potentially significant prognostic factors on locoregional control, disease free survival and overall survival. Histology, extent of parametrial involvement on physical examination and paraaortic lymph node metastasis on CT were found to have prognostic significance in the carcinoma of uterine cervix stage IIB.

  • PDF

Does Microinvasive Adenocarcinoma of Cervix Have Poorer Treatment Outcomes than Microinvasive Squamous Cell Carcinoma?

  • Ruengkhachorn, Irene;Hanamornroongruang, Suchanan;Leelaphatanadit, Chairat;Sangkarat, Suthi
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.8
    • /
    • pp.4013-4017
    • /
    • 2016
  • Background: To compare the pathological findings and oncologic outcomes of stage IA cervical carcinoma patients, between adenocarcinoma and squamous cell carcinoma cases. Materials and Methods: A total of 151 medical records of stage IA cervical carcinoma patients undergoing primary surgical treatment during 2006-2013 were reviewed. Information from pathological diagnosis and recurrence rates were compared with descriptive statistical analysis. The Kaplan-Meier method and Cox proportional hazards model were used for survival analysis. Results: The median age was 48.9 years. There was no significant difference in rates of lymph node, parametrium, uterine, vaginal, or ovarian metastasis, when comparing adenocarcinoma with squamous cell carcinoma. Overall recurrence rates of adenocarcinoma (5.7%) and squamous cell carcinoma (2.6%) were not statistically significant different, even when stratified by stage. When comparing progression free survival with squamous cell carcinoma, adenocarcinoma had an HR of 0.448 (0.073-2.746), p=0.386. Conclusions: Microinvasive adenocarcinoma of cervix has similar rate of extracervical involvement and oncologic outcomes to squamous cell carcinoma.

Association of Educational Levels with Survival in Indian Patients with Cancer of the Uterine Cervix

  • Krishnatreya, Manigreeva;Kataki, Amal Chandra;Sharma, Jagannath Dev;Nandy, Pintu;Gogoi, Gayatri
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.8
    • /
    • pp.3121-3123
    • /
    • 2015
  • The main objective of this paper was to assess the influence of educational level on the survival of uterine cervix cancer patients in our population. A total of 224 patients were registered in our registry, of which 178 had information on stage and different educational levels. The overall median survival (MS) was 23 months, with values of 18.5, 20.7 and 41.3 months for the illiterate, literate and qualified groups, respectively. In the illiterate patients, stage I was seen in 2.6% and stage IV in 11.8%, while in other 2 groups stage I was seen in 10% to 17% of patients at the time of diagnosis. The survival probability at around 50 months was around 42%, 30% and 26% (approximately) for qualified, literates and illiterates respectively [Log Rank (Mantel-Cox) showed p=0.023]. Emphasis on imparting education to females can be a part of comprehensive cancer control programme for improving the overall survival in patients with carcinoma of the uterine cervix in our population.