• Journal of The Korean Society of Clinical Toxicology
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• v.4 no.1
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• pp.65-68
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• 2006

Contact urticaria describes a wheal and falre response elicitied within 30-60 minutes after cutaneous exposure to certain agents. Contact urticaria encompasses a number of different clinical manifestations and the symptoms which can vary from the mildest forms of burning, stinging and itching sensation to life-threatening anaphylaxis referred to as contact urticaria syndrome. Cefotiam is one of the most popular second generation cephem antibiotic used in korea. Since 1975, contact urticaria due to cephalosporins has been reported, and also, in japan, this reported from about last 15 years. Recently we experienced three nurses working at the general wards with showing contact urticaria and anaphylaxis after occupational exposure to cefotiam antibiotics.

• Clinical and Experimental Pediatrics
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• v.58 no.5
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• pp.159-164
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• 2015

Most guidelines for chronic urticaria (CU) in infants and children are based on limited pediatric evidence. Current evidence used to guide treatment in children is extrapolated from data focusing on older age groups. CU in children is a different and complex condition than that in adults. Furthermore, there is little published information regarding urticaria in Korean children. The aim of the present article is to review recent research on chronic childhood urticaria and improve the current understanding of its pathogenesis and management. The classification and definition of urticaria in adults also applies to children. CU is defined as a daily occurrence of spontaneous wheals, angioedema, or both for >6 weeks. The precise pathophysiology of CU is unknown and the rates of successful identification of a cause in children with CU vary from 20%-50%. There is no established laboratory test to evaluate the presence of urticaria. The natural course of childhood CU is undetermined, with limited reports discussing long-term outcomes. Second-generation H1 antihistamines are the cornerstone of management, while limited therapeutic drugs are available for adults.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.10 no.1
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• pp.357-366
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• 1997

Urticaria is an erythematous or white non-pitting edematous plague that changes in size and shape by peripheral extention or regression during the few hours or days. Urticaria is classified as acute or chronic type. The etiology of acute urticaria has been determined in many case, but the cause of chronic urticaria has been determined in only $5\%\;to\;20\%$ of cases. This observation was aimed to evaluate the clinical manifestations and clinical indence of urticaria seen between June, 1995 and November, 1996(18months) at the Department of Dermatology, Oriental Medical Hospital, Kyung Hee University. The results were summarized as follows ; 1. In the cases of 106 patients, $43\%\;were\;male\;and\;51\%$ were female. 2. The pick incidence of age group was 20 to 29($32\%$). 3. The most frequent duration of urticaria was from 2 months to 6 months. 4. In this study, the inciting causes could not be found in $61\%\;of\;acute\;patients,\;60\%$ of chronic patients. 5. Among 107 patients, $5\%$ of all patients had personal history of atopic diseases and $9\%$ of all patients had familly history. 6. Angioedema was founded in 7 patients, and the most common involved site were lips, eyelids and tongue. 7. The most frequently treated prescription was Chhunggisan which occupied $51\%$ of all, Gyakhangjunggisan(41\%$) and Gosamhomasan($25\%$), Bangpoongtongsungsan($22\%$) in that order of frequency.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.26 no.4
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• pp.60-69
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• 2013

Objective : This case series study was designed to assess the effect of Gamisungmagalguntang for chronic urticaria identified as "Wind-Heat" pattern by retrospective methods. Methods : We treated 19 patients for chronic urticaria with Gamisungmagalguntang(加味升麻葛根湯), who visited to care chronic urticaria at the department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine at Kyunghee University Korean Medical Center from 1st January 2013 to 31st August 2013. We analyzed information and body conditions of 19 patients. And by using Urticaria Activicy Score(UAS), frequency and number of wheals, itch severity and total score on a 4-point(0-3) scale were assessed in 19 patients. The change of each criterion and total scores between baseline and follow up were analyzed using paired t-test and Wilcoxon test(p<0.05). Results : 1. UAS improvement was statistically significant(p<0.001). Effects of symptom improvement were excellent(31.58%) that means symptom remission and good(42.10%) that means symptom improved over 50%. 2. Heat sensitivity as suspected provocation factor could be a marker for the Wind-Heat pattern urticaria. 3. Among the Wind-Heat pattern urticaria patients, normal digestion(52.63%) and no thirst(78.95%) were higher than abnormal conditions. Whereas about sweat item, abnormal conditions(57.89%) were higher than normal. That means abnormal sweat conditions could be a marker for a defense qi(衛氣) dysfunction of the Wind-Heat pattern urticaria. Conclusions : Our findings suggest that Gamisungmagalguntang could be effective on the Wind-Heat pattern urticaria.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.3
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• pp.220-227
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• 2009

Acquired hypohidrosis is a rare condition of unknown pathogenesis, while idiopathic cholinergic urticaria is relatively common. We report the case of a 18-year-old male with idiopathic cholinergic urticaria and acquired hypohidrosis. He presented with an intermittent pruritic eruption precipitated by mild activity, such as mild exercise or laughing, for last 4 years. He was diagnosed with cholinergic urticaria associated acquired hypohidrosis, successfully treated by herbal medicine applied Gejimahwanggakban-tang(桂枝麻黃各半湯).

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.15 no.1
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• pp.151-161
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• 2002

For the purpose of treating for urticaria, they orderly use LI, B, GV in acute stage, and use the kyunghyul of Sp, CV, P, Liv, L in chronic stage. we can presume that in the past, they must select these kyunglak and kyunghyul by the phase and the period of the urticaria. To approach to treating urticaria, it is necessary the selecting of kyunghyul by the phase and period of the urticaria.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.3
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• pp.153-161
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• 2020

Objectives : This study was carried out to investigate the effect of Gyejiyiwolbiyil-tang on Urticaria. Methods : We treated 14 Urticaria patients. We evaluated severity of welts, pruritus, heat and redness by using the Visual Analogue Scale(VAS). Results : After the treatments, all patients objective score of urticara was remarkably decreased. Conclusions : This study suggests that Gyejiyiwolbiyil-tang is effective against acute and chronic urticaria.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.28 no.3
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• pp.88-100
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• 2015

Objectives : This study was designed to assess the effect of Soyangin Medicines on Soyangin chronic urticaria patients by retrospective methods.Methods : We treated 37 Soyangin chronic urticaria patients who visited Haneulmaeum Korean Medicine Clinic from September 1st 2011 to June 30th 2014. We administrated the Soyangin patients with Soyangin Medicines such as Hyeongbangsabaek-san(荊防瀉白散), Yanggyeoksanwha-tang(凉膈散火湯) and so on for 3 months. We measured the effect biweekly by using Urticaria Activity Score(UAS). We analyzed the information and medical history of patients by Frequency analysis, and UAS by Repeated measures, ANOVA.Results & Conclusions : Every items of UAS were improved by Soyangin Medicines. And the improvement was statistically significant(p<0.05).

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.1
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• pp.252-255
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• 2008

Phlegm-retention disease, which is called dameum(痰飮), is a kind of a pathologic secretion products, accumulated excessive water in a special part of a body. Urticaria is a common dermatopathy, coming under “eun-jin(隱疹)” in Korean herbal medicine. Headache and vertigo is a very common diseases in life. There are so many causes which induce uticaria, headache and vertigo. We experienced 31-year old woman case suffering from chronic urticaria, headache, vertigo with digestive disorder, nausea. We diagnosed those symptoms as dameum(痰飮). So we administered Jeongjeongamiyijintang-gamibang(正傳加味二陳湯加味方) to the urticaria, and Banhabaekchulcheonma-tang (半夏白朮天麻湯) to the headache, vertigo. They are both famous herbal medicines for treating dameum-related symptoms, because both of them contains Yijin-tang(二陳湯) which is the main Herbal medicine for dameum(痰飮). We suggest that dameun-related urticaria, headache, vertigo can be treated by preceding medicines.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.3
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• pp.262-268
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• 2019

Objectives : The purpose of this study to report the effect of Socheongryong-tang on solar urticaria. Methods : We treated a 26-years-old woman patient with Solar urticaria on the whole body with Korean medicine. After Korean medical treatment for 7 days, we have confirmed the improvement and disappearance of rashes, wheals, and itching. We recorded pictures of changes on symptoms. Results : After the treatment the grade of VAS was decreased. And rashes, wheals, itching were disappeared. Conclusions : Socheongryong-tang showed improvement in symptoms with solar urticaria. Thus, It is concluded that Socheongryong-tang is effective on the treatment of skin diseases such as solar urticaria.