• Biomolecules & Therapeutics
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• v.23 no.1
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• pp.12-18
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• 2015

Skin is an emerging target tissue in pharmaceutical and cosmetic science. Safety assessment for dermal toxicity is a critical step for development of topically applicable pharmaceutical agents and ingredients in cosmetics. Urgent needs exist to set up toxicity testing methods for dermal safety, and identification of novel biomarkers for pathological cutaneous alteration is highly required. Here we will discuss if vascular endothelial growth factor (VEGF) has a potential as a biomarker for dermal impairment. Experimental and clinical evidences for induction of keratinocytic VEGF under pathological conditions will be reviewed.

• Journal of the Korea Safety Management & Science
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• v.15 no.3
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• pp.113-125
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• 2013

According to 2012 OECD environmental report, Korea was ranked as the first country of water stress. Water footprint is a method to calculate water usage during the life cycle of a product from material procurement through production to disposal to recycle and to quantify the load to water resources. In water footprint calculation, water consumption unit is used. Agricultural water use is over 48% so it is urgent to mange that area Korea needs to spread the discussion about water footprint as quickly as possible, for the study to prevent social and environmental problems due to water shortage. This paper, through water footprint calculation and comparison in Chungju and Geochang areas, looks to counter measures for water risk, targeting domestically-produced apple.

• The Journal of Sustainable Design and Educational Environment Research
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• v.13 no.1
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• pp.32-40
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• 2014

In an effort to resolve environmental pollution problems, developed countries enforce green building certification systems. The same is true in Korea. However compared professional accreditation system to certification systems did not systematically in Korea. Therefore, in accordance with development of green building related systems and technology the requirement for foster green building professionals is urgent. Accordingly this study is purposed to analyze and propose that green building professional accreditation system development and operation of the direction. Through data analysis domestic and international green building professional accreditation system for draw a development plan. And then conduct an expert Delphi survey reflected in the survey results to development plan.

• Convergence Security Journal
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• v.4 no.3
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• pp.27-35
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• 2004

A current trend in telecommunication is the convergence of wireless communication and computer network technologies, and the emergence of wireless application protocol(WAP) devices is an example. Computer system managers are often requested to solve urgent system problems. Many times, they cannot access a computer to perform remote system management tasks. Aiming at solving this problem, this paper presents a novel tool for system management that uses a WAP interface, and focuses on the description of the architecture and the associated application modules.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.16 no.4
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• pp.219-224
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• 2013

Acute abdominal pain is a common complaint in childhood, and it can be caused by a wide range of underlying surgical and non-surgical conditions. The most common non-surgical condition is gastroenteritis, while the most common surgical condition is appendicitis. Abdominal pain in children varies with age, associated symptoms, and pain location. Although acute abdominal pain is usually benign and self-limiting, there are uncommon but life-threatening conditions that require urgent care. Meticulous history taking and physical examinations are essential to determine the cause of acute abdominal pain and to identify children with surgical conditions such as appendicitis.

• Journal of the Ergonomics Society of Korea
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• v.5 no.2
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• pp.17-25
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• 1986

In recent years, the average life span of people in advanced countries has increased. Conwequently, the number of middle-aged and old workers who have the will to work has increased. On the other hand, the declining birth rate has decreased the number of young workers. However, because many enterprises in advanced countries have extended their mandatory retirement age from 55 to 60 years, labor accidents involving aged workers are on the increase. As a result, the need for a method to evaluate the work skills of middle-age and old workers has become urgent. To explore one such method, this study investigated the relationship between aging and manual dexterity. Dexterity was found to deteriorate with age, but with large variability from individual to individual. The parameters of dexterity used in this experiment were found to be reliable.

• Electronics and Telecommunications Trends
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• v.35 no.6
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• pp.12-23
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• 2020

Because of economic polarization and difficulties, extreme personalization, and the complexity of social relationships, modern people are experiencing various mental disorders or pathologies. Accordingly, there is an urgent need to prepare more active countermeasures and support those with mental health difficulties to improve mental health and prevent abnormal pathologies. Artificial intelligence (AI) is expected to improve the mental health of individuals through emotional enhancement beyond affective computing. We investigated how to use AI to prevent and diagnose mental diseases or disorders, support treatment, and manage followup. In particular, promising services that can be used in daily life or medical clinics were discovered and active directions for realizing these services are suggested.

• International Commerce and Information Review
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• v.11 no.4
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• pp.373-394
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• 2009

As Korea-EU FTA has established, the strategy and counteractive measures of Japan have been rising. EU accounts for 33% of GDP and has a lot of population, which makes up 7.1% in the world. Besides, it has a great market, which, amounts to 4.3 trillion. Japanese government indicated that as Korea has established FTA with the U.S.A. and has negotiated with EU, the necessity to cope with in the field of automobile, machinery, and appliances is urgent. To recognize competitive areas in the market of EU between Korea and Japan, this paper focuses that we need to notice Japan's access toward EU and the present situation about trade and customs. Second, it investigates that Japan is in competitive with Korea in which kind of industrial area.

• Journal of Industrial Technology
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• v.36
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• pp.9-16
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• 2016

In the face of increasing impact of climate change due to human activities, there has been an urgent need to resolve the problem in water resources planning management and environmental engineering. Therefore SWAT model was used to identify the impacts and change in hydrological cycle and environmental aspect. The most important step for the development of SWAT model is calibration procedure. Therefore, SWAT-CUP automatic calibration module was used to find some optimal parameters in SWAT model. After calibration in the cheongmicheon basin, SWAT model is used for the projected precipitation and temperature of RCP 4.5 and 8.5 climate change scenarios in AR5. The quantity and quality using SWAT model from 2014 to 2100 were identified. Finally, this study can provide the reasonable finding on impact by climate change.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8007-8018
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• 2014

Cervical cancer is the most common gynecologic malignancy worldwide and development of new therapeutic strategies and anticancer agents is an urgent priority. Plants have remained an important source in the search for novel cytotoxic compounds and several polyphenolic flavonoids possess antitumor properties. In this review article, data about potential anticarcinogenic activity of common natural flavonoids on various human cervical cancer cell lines are compiled and analyzed showing perspectives for the use of these secondary metabolites in the treatment of cervical carcinoma as well as in the development of novel chemotherapeutic drugs. Such anticancer effects of flavonoids seem to differentially depend on the cellular type and origin of cervical carcinoma creating possibilities for specific targeting in the future. Besides the cytotoxic activity per se, several flavonoids can also contribute to the increase in efficacy of conventional therapies rendering tumor cells more sensitive to standard chemotherapeutics and irradiation. Although the current knowledge is still rather scarce and further studies are certainly needed, it is clear that natural flavonoids may have a great potential to benefit cervical cancer patients.