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Effects of exogenous lactate administration on fat metabolism and glycogen synthesis factors in rats

  • Kyun, Sunghwan;Yoo, Choongsung;Hashimoto, Takeshi;Tomi, Hironori;Teramoto, Noboru;Kim, Jisu;Lim, Kiwon
    • Korean Journal of Exercise Nutrition
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    • v.24 no.2
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    • pp.1-5
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    • 2020
  • [Purpose] Lactate has several beneficial roles as an energy resource and in metabolism. However, studies on the effects of oral administration of lactate on fat metabolism and glycogen synthesis are limited. Therefore, the purpose of the present study was to investigate how oral administration of lactate affects fat metabolism and glycogen synthesis factors at specific times (0, 30, 60, 120 min) after intake. [Methods] Male Sprague Dawley (SD) rats (n = 24) were divided into four groups as follows: the control group (0 min) was sacrificed immediately after oral lactate administration; the test groups were administered lactate (2 g/kg) and sacrificed after 30, 60, and 120 min. Skeletal muscle and liver mRNA expression of GLUT4, FAT/CD36, PDH, CS, PC and GYS2 was assessed using reverse transcription-polymerase chain reaction. [Results] GLUT4 and FAT/CD36 expression was significantly increased in skeletal muscle 120 min after lactate administration. PDH expression in skeletal muscle was altered at 30 and 120 min after lactate consumption, but was not significantly different compared to the control. CS, PC and GYS2 expression in liver was increased 60 min after lactate administration. [Conclusion] Our results indicate that exogenous lactate administration increases GLUT4 and FAT/CD36 expression in the muscle as well as glycogen synthase factors (PC, GYS2) in the liver after 60 min. Therefore, lactate supplementation may increase fat utilization as well as induce positive effects on glycogen synthesis in athletes.

Employing Magnetic Resonance Imaging(MRI) in the Estimation of the Biomechanical Body Segment Parameters of Korean Adults (MRI에 의한 한국인 신체분절의 생체역학적 모수치 산출)

  • Joo, Young-Hwa
    • Korean Journal of Applied Biomechanics
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    • v.12 no.1
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    • pp.233-249
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    • 2002
  • The purpose of this study was to employing MRI in the estimation of the biomechanical body segment parameters of Korean adults. for this purpose MRI study on 19 Korean living subjects were used to measurement. All the parameters that was concerned were inertial characteristics of human body mass of each segment, center of mass of them and the length of radius of gyration of them. The cross sectional images and saggital images of every 1cm interval were got using the 0.5 Tesla MRI from the top of head to the bottom of foot, whole body. And then, by tracing the images of the film and scanning them, got the area which the several tissues occupied in the image of slice. By summing the area of slice of each segment which were calculating and by multipling the density of the tissues, got the mass of segment and other inertial characteristics. The ratios of radius of gyration in both transverse axis and longitudinal axis though the segmental mass and segment length are as follow: male A : head($0.229\pm0.0029$), neck($0.256\pm0.0095$), thorax($0.374\pm0.0059$) abdomen($0.245\pm0.0020$), pelvis($0.368\pm0.0106$), thigh($0.288\pm0.0030$) shank($0.280\pm0.0043$), foot($0.277\pm0.0195$), upperarm($0.311\pm0.0074$) forearm($0.286\pm0.0051$), hand($0.253\pm0.0095$) female A : head($0.214\pm0.0032$), neck($0.254\pm0.0112$), thorax($0.295\pm0.0061$) abdomen($0.289\pm0.0021$), pelvis($0.329\pm0.0108$), thigh($0.288\pm0.0036$) shank($0.280\pm0.0047$), foot($0.243\pm0.0206$), upperarm($0.279\pm0.0083$) forearm($0.286\pm0.0048$), hand($0.229\pm0.0097$) male B : head($0.532\pm0.0006$), neck($0.533\pm0.0006$), thorax($0.658\pm0.0008$) abdomen($1.350\pm0.0022$), pelvis($0.875\pm0.0002$), thigh($0.213\pm0.0001$) shank($0.160\pm0.0001$), foot($0.152\pm0.0002$), upperarm($0.136\pm0.0002$) forearm($0.202\pm0.0002$), hand($0.273\pm0.0006$) female B : head($0.198\pm0.0002$), neck($0.335\pm0.0011$), thorax($0.238\pm0.0001$) abdomen($0.888\pm0.0001$), pelvis($1.318\pm0.0117$), thigh($0.095\pm0.0001$) shank($0.075\pm0.0001$), foot($0.181\pm0.0006$), upperarm($0.0.062\pm0.0001$) forearm($0.083\pm0.0001$), hand($0.105\pm0.0007$).

Contents Analysis of the Tennis Wear Design on Female Professional Tennis Players in Sport Industry (스포츠 산업에서 여성 프로 테니스 선수들이 착용한 테니스 웨어 디자인의 내용분석연구)

  • Kim, Jang-Hyeon;Lee, Ji-Yeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.12
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    • pp.186-196
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    • 2018
  • Sports has become one way to improve our own health and to enjoy life by changing the lifestyle of modern-day people. Sports athletes not only give pleasure to the public, but also play a role in elevating a nation's reputation through sports. Tennis is popular with the public, and women players receive tennis wear from various sports companies to promote the designs to the public. This study considers the design-related characteristics of women's tennis wear through content analysis of design elements from the tennis wear in four major tournaments over the most recent five years. This is important in order to provide basic data on design directions for tennis wear in the future. The results of this study are as follows. First, the silhouette plays a role in enhancing activity by considering the physical movement of tennis players who are very active. Second, color emphasizes the rules and clarity of traditional tennis tournaments, and reflects a diversified trend in tennis wear by considering smooth game play by players and combining popular colors in the year. Third, patterns and decorations on material are used as a means to emphasize the esthetics of tennis wear, and tape plays an auxiliary role in emphasizing the physical beauty of women or preventing physical movement causing injury. In addition, sponsor logos are generally located at the center of the chest of tennis wear tops by mixing letters and images. This can be interpreted as a part of the marketing strategy to enhance clarity of the sponsor's brand.

The Effect of the Combined Stretching and Strengthening Exercise on the Clinical Symptoms in Posterior Tibial Tendon Dysfunction Patient (후방 경골 건 기능부전 환자의 임상 증상에 운동 치료가 미치는 영향)

  • Jeong, Tae-Ho;Oh, Jae-Kun;Lee, Hong-Jae;Yang, Yoon-Joon;Nha, Kyung-Wook;Suh, Jin-Soo
    • Journal of Korean Foot and Ankle Society
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    • v.12 no.1
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    • pp.47-54
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    • 2008
  • Purpose: The isolated exercise therapy and its effect for the treatment of posterior tibial tendon dysfunction (PTTD) is not well known. The purpose of this study was to identify the clinical effect of stretching and strengthening exercise program on the patients' muscle function and range of motion, pain and gait in the management of the early stage PTTD. Materials and Methods: From October 2006 to March 2007, 14 patients with early stage PTTD (stage I or IIa) without surgical intervention were randomly assigned into two groups and we analyzed their clinical results. All patients were female and one who have sprained the same ankle during the program and one who withdrew from the program due to her private reason were excluded. At the last, the exercise group (EG) was seven and the control group (CG) was five. Mann-Whitney U test was used for the comparison of pain, ROM, muscle power, AOFAS score and 5 minute walking test of both groups. Wilcoxon-signed rank test was used for the comparison between the pre and post exercise program in EG. Results: The pain was significantly reduced in EG compare to CG and only the dorsiflexion was significantly increased in EG in the analysis of ROM. The dorsi flexion and plantar flexion power were significantly increased in EG. Conclusion: Our 6 weeks stretching and strengthening exercise program showed noticeably improved clinical result, and therefore it is recommended as one of the useful treatment option in the management of early stage PTTD.

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Effect of exercise on cystatin C as a risk factor for renal failure and hypertension

  • Kwon, Yoo Chan;Park, Sang Kab;Park, Hyun Tae;Kim, Eun Hee;Park, Jin Kee;Jang, Jae Hee
    • Korean Journal of Exercise Nutrition
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    • v.16 no.1
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    • pp.27-33
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    • 2012
  • This study was conducted to investigate the effect of a 24-week combined exercise training program in older women with hypertension. Women with hypertension who were 70 years and older were randomized into two groups: combined exercise group (CE; n = 15) and a control group (n = 15). The CE group performed a combined exercise training program four times per week for 24 weeks and the control group did not. Five factors, including body composition (percent body fat and skeletal muscle mass), health-related physical fitness, adipocytokines (interleukin-6 [IL-6] and tumor necrosis factor-alpha [TNF-α]), kidney risk factors (glomerular filtration rate [GFR] and cystatin C), and systolic and diastolic blood pressure were measured before and after the program. The findings showed that total muscle mass, health-related physical fitness factors, and GFR increased significantly in the CE group compared to those in the control. Additionally, systolic and diastolic blood pressure and IL-6, TNF-α, and cystatin C levels in the CE group decreased significantly after the intervention. In contrast, total muscle mass decreased significantly and blood pressure remained unchanged in the control group. These results suggest that CE training may positively impact circulating levels of adipocytokines and cystatin C and improve physical fitness levels in elderly women with hypertension. Therefore, CE training helps to prevent renal disease and improve health-related physical fitness, eventually leading to a better quality of life.

Effect of Auricular Acupress Therapy on Insomnia of Cancer Patients : Randomized, Single Blinded, Placebo Controlled Trial (이압요법이 암환자의 불면증에 미치는 효능 : 무작위배정, 단일맹검, 위약대조군 연구)

  • Jung, In-Sook;Kim, Jung-Sun;Yoo, Hwa-Seung
    • Journal of Pharmacopuncture
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    • v.13 no.2
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    • pp.93-100
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    • 2010
  • Background: Auricular acupressure is one of the traditional health care treatments in oriental medicine. Approximately, 30~40% of the cancer patients have said to be suffering from insomnia and half of them having chronic and severe insomnia at the same time. Insomnia caused cancer patients feel more pain, fatigue, depression and anxiety and it sometimes let the power to have the best of cancer pull down. Objective: To investigate how effective the auricular acupressure treatment to cancer patients suffering from insomnia. Methods: We recruited participants from East-West Cancer Center of Daejeon University. Finally, of the people whose age range from 20 to 75, 12 patients who got less than 40 points from the score of Oh's sleeping score (OSS) were recruited. Single-blind, randomized pilot study was performed. The treatment group received auricular acupressure treatment (AAT) on active points and the control group had received sham acupressure treatment (SAT) for five times. Sleep parameters were checked by using OSS and numeric rating scale (NRS). We checked the scale everytime, both before and after treatment. We analyzed the data statistically by using independent T-test, paired T-test and analysis of variance (ANOVA) test. (p<0.05) Results: Twelve cancer patients participated in this pilot study and there was no significant difference between control and treatment group. Only 7 of them had completed the whole treatment process, 4 patients of AAT group and 3 participants of SAT. The OSS of AAT group had increased from $34.0{\pm}4.3$ to $39.5{\pm}3.1$ and that of SAT group had increased from $38.3{\pm}3.5$ to $40.0{\pm}0.0$. There was no significant difference between them. The NRS of AAT group had increased from $6.3{\pm}2.9$, $04.8{\pm}2.1$ and that of SAT group had increased from $7.0{\pm}1.0$ to $5.0{\pm}2.6$. No significant difference was observed between them. Conclusion: Although both groups did not show significant differences, most of the experimental participants showed increasing OSS and NRS after treatments. Significant participants' number will be needed in the next study.

Comparison of the Duration of Hamstring Flexibility Improvement Following Termination of Modified Dynamic Stretching, Hold-Relax, and Static Stretching

  • Moon, A-Young;Jang, Hee-Jin;Jang, Hyun-Jeong;Kim, Suhn-Yeop
    • Physical Therapy Korea
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    • v.21 no.1
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    • pp.47-54
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    • 2014
  • The aim of this study was to compare the duration of hamstring flexibility improvement after 3 stretching interventions in people with limited hamstring flexibility. Twenty-two subjects (12 men, 10 women) with limited hamstring flexibility of the dominant leg received 3 stretching interventions- modified dynamic stretching (MDS), hold-relax (HR), and static stretching (SS)-in a random order. All the subjects received all 3 interventions at intervals of at least 24 hours to minimize any carry-over effect. Modified dynamic stretching was applied as a closed kinetic chain exercise in the supine position by using the sling suspension system (Redcord Trainer(R)). The SS and HR interventions were individually performed in the straight leg raising (SLR) position, and all 3 interventions were performed for 3 minutes. Outcome measures included passive knee extension (PKE) measurements. Five post-test measurements were recorded for all subjects at 3, 6, 9, 15, and 30 minutes after the interventions. MDS was associated with a significant increase in knee extension range of motion even at 30 minutes post-treatment. In contrast, the HR and SS stretching methods showed increased hamstring flexibility for only 6 minutes post-treatment. Improvements in the range of motion of knee extension (indicating enhancement in hamstring flexibility) with MDS were maintained longer than those with the HR and SS interventions. Therefore, MDS may be more effective than the other interventions for maintaining hamstring flexibility.

Effect of Basal Physical Fitness and ADL Function in the Aged According to Horse Riding Exercise (실내 승마운동이 고령자의 기초체력 및 ADL 기능에 미치는 효과)

  • Kim, E.R.;Kang, S.R.;Yu, C.H.;Moon, D.A.;Park, S.Y.;Kwon, T.K.
    • Journal of Biomedical Engineering Research
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    • v.34 no.4
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    • pp.163-169
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    • 2013
  • The purpose of this study was to verify exercise effect of horse riding exercise according to estimate basal physical fitness and activities of daily living(ADL) function in the aged. Participants were nineteen peoples who have no impediment of activity. They performed horse riding exercise using SRider(Neipplus, Co., Korea) at sixty minutes a day. Exercise has progressed three days a week for eight weeks. We measured trunk flexion, sit up, whole body reaction, leg strength and maximal oxygen uptake as basal physical fitness. Also three meter gait, single stance with eyes opened and single stance with eyes closed as ADL function were estimated once a month. The result of legs strength and whole body reaction showed the higher significantly than before the exercise. Moreover, the result of three meter walking ability only increased significantly among the ADL function. This means that horse riding exercise might be activated continuous muscular contraction with maintained tonus of muscle. We thought that continuous movement of horse riding could be lead to isometric muscle contraction in lower limbs. Our study found that horse riding exercise could improve lower strengths and muscle reaction for exercise effect. Also we suggested that horse riding exercise could be adapted to exercise methods that could provide rehabilitation and treatment enough for the aged or disabled person.

Prediction of Health Care Cost Using the Hierarchical Condition Category Risk Adjustment Model (위계적 질환군 위험조정모델 기반 의료비용 예측)

  • Han, Ki Myoung;Ryu, Mi Kyung;Chun, Ki Hong
    • Health Policy and Management
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    • v.27 no.2
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    • pp.149-156
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    • 2017
  • Background: This study was conducted to evaluate the performance of the Hierarchical Condition Category (HCC) model, identify potentially high-cost patients, and examine the effects of adding prior utilization to the risk model using Korean claims data. Methods: We incorporated 2 years of data from the National Health Insurance Services-National Sample Cohort. Five risk models were used to predict health expenditures: model 1 (age/sex groups), model 2 (the Center for Medicare and Medicaid Services-HCC with age/sex groups), model 3 (selected 54 HCCs with age/sex groups), model 4 (bed-days of care plus model 3), and model 5 (medication-days plus model 3). We evaluated model performance using $R^2$ at individual level, predictive positive value (PPV) of the top 5% of high-cost patients, and predictive ratio (PR) within subgroups. Results: The suitability of the model, including prior use, bed-days, and medication-days, was better than other models. $R^2$ values were 8%, 39%, 37%, 43%, and 57% with model 1, 2, 3, 4, and 5, respectively. After being removed the extreme values, the corresponding $R^2$ values were slightly improved in all models. PPVs were 16.4%, 25.2%, 25.1%, 33.8%, and 53.8%. Total expenditure was underpredicted for the highest expenditure group and overpredicted for the four other groups. PR had a tendency to decrease from younger group to older group in both female and male. Conclusion: The risk adjustment models are important in plan payment, reimbursement, profiling, and research. Combined prior use and diagnostic data are more powerful to predict health costs and to identify high-cost patients.

Effect of Rowing Ergometer Training on the Aerobic Capacity and Strength of Male High School Students (로잉 에르고미터 훈련이 남자고등학생의 유산소능력과 근력에 미치는 효과)

  • Kim, Dong-Hee;Yuk, Ji-Min;Park, Hyeok;Lim, Jae-Heon;Kim, Seok-Hwan
    • PNF and Movement
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    • v.16 no.2
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    • pp.187-194
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    • 2018
  • Purpose: This study aimed to assess the effect of rowing ergometer training on the aerobic capacity and strength of male high school students over a 12-week period. Methods: Fourteen high school students volunteered to participate in the study. The subjects were divided into two groups: seven subjects in the experimental group and seven in the control group. The subjects in the experimental group performed rowing ergometer training for 75 min per session at three days a week for 12 weeks. The exercise intensity set the maximum heart rate (HRmax) from 40% to 80%. Aerobic capacity was measured by ventilation, cardiac output, and oxygen intake per body weight. Strength was measured by grip strength and back strength before and after training. Results: A significantly increased ventilation (p=0.01), cardiac output (p=0.01), and oxygen intake per body weight (p=0.00) were found in the experimental group. A significantly increased grip strength in the right and left hands (p=0.00, 0.00) and back strength (p=0.04) were observed in the experimental group. Conclusion: Rowing ergometer training can be an effective combined exercise for aerobic capacity and strength of high school students.