• Archives of Pharmacal Research
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• v.17 no.5
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• pp.298-303
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• 1994

4-Arylazo-1H-pyrazol-3, 5-idimines 1a-c reacted with bromomalononitrile (2) to yield the corresponding imidazo[1, 2-b]pyrazoles 3a-c. The latter reacted with some active methylene compounds and with .alpha.-cinnamonitriles to afford the corresponding pyrazoloimidazopyridines 6, 8, 9 and 15, respectively. Compounds 3 reacted with each of formic acid, formamide, trichlo-roacetonitrile and with guanidine to yield the corresponding pyrazoloimidazopyrimidines 16-19 respectively.

• Archives of Pharmacal Research
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• v.15 no.2
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• pp.130-133
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• 1992

A series of copper complexes of some amino acid derivatives of 6-methoxy 3-methyl-coumarilic acid were prepared. The infrared, visible spectra and magnetic susceptibility of these compounds were reported. All copper complexes were foundt to have antimicrobial activity against gram-positive bacteria only.

• Journal of Korean Society of Archives and Records Management
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• v.19 no.4
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• pp.35-61
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• 2019

The recent demographic cliff caused the schooling population to steadily decline and the number of college admissions to sharply drop, which led to the prediction of the Ministry of Education wherein 38 universities in Korea will be closed within the next 3 years. As such, the legal, administrative, historical, and informational values of university records shed light on the importance of the follow-up process and management of closed university records. Although closed university records need to be systematically managed according to legal procedures similar to other public records, there is no practical and clear legal standard for the management of such records at present. Moreover, management standards considering the characteristics of (closed) university records and individual universities' situations and specificity have been insufficient. This study, therefore, examines the ambiguous standards for closed university records management and analyzed relevant problems. Furthermore, an integrated management system is suggested as a way to improve the records management of closed universities.

• Journal of Korean Society of Archives and Records Management
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• v.19 no.3
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• pp.1-27
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• 2019

Student records are essential for the functional, social, and personal aspects of the university. However, it is difficult to systematically manage such records because of the vast amount produced by several agents, the decentralization of the university's records management system, and various types and forms produced. Despite acknowledging the importance of student records, Myongji University implements its records management system at a sluggish pace. This study defined students' records except for the administrative records of the university as "student-related records" and categorized them into education records, student creation and research records, and student activity records. After examining the best practices in Korea and abroad, we reviewed the current status of Myongji University's student records management system and proposed appropriate and comprehensive management plans accordingly.

• Archives of Pharmacal Research
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• v.11 no.3
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• pp.244-246
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• 1988

Sulphamerazine-$N^1$-(methyl 2,3,4-tri-O-acetyl-${\beta}$-D-glucuronide) was successfully synthesized and characterized by proton NMR and mass spectrometry for the metabolic study of sulphamerazine.

• Archives of Pharmacal Research
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• v.12 no.2
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• pp.103-107
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• 1989

Several new 1,2,4-triazolo[5,1-a]pyrimidine derivatives were synthesized via the reactions of 3-amino-1,2,4-triazole with active methylene nitrites and thier ylidene derivatives. The structures assigned for the reaction products were based on elemental analyses and spectral data.

• Archives of Pharmacal Research
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• v.15 no.3
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• pp.229-233
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• 1992

The pKa value of histidine-51 residue was determined by the pH dependency of contents of NADH bound to the active site in the orse liver alcohol dehydrogenase and % inactivation with diethyl pyrocarbonate treatment of the enzyme. The pKa for His-51 was -7.15 in the ternary complex and -6.7 in the enzyme itself.

• Archives of Pharmacal Research
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• v.16 no.1
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• pp.62-67
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• 1993

A series of 12 pyrimidine derivatives were prepared and tested in vitro against growth, sporulation and nucleic acids of Fusarium oxysporum f. sp. lycopersici and Helminthosporium oryzae. Intorduction of thiazole ring together with two aryl groups to 2-aminopyrimidine induced drastic toxicity for both fungi. Pyrimidine derivatives with aryl groups were less toxic. Nitro groups were found to enhance the toxicity of the pyrimidine derivatives especially when substituted in ortho-position of the aryl groups. Inhibition of nudeic acids synthesis of both fungi was attributed mainly to the presence of thiazole ring.

• Archives of Pharmacal Research
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• v.16 no.1
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• pp.29-31
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• 1993

A methanol extract of the roots of bupleurum longiradiatum (Umbelliferar) showed antiinflammatory activity in rats. Hexane, chloroform, butanol, and aqueous fractions from the methanol extract were tested with the result that only the hexane fraction exhibited positive activity. Fractionation of the hexane extract resulted in isolation of arborinone as an active principle.

• Archives of Pharmacal Research
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• v.23 no.6
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• pp.574-578
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• 2000

Protected $\alpha$-Phenyl glycine 17 and phenylalanine 18 and 19 have been synthesized through an efficient three-step sequence from the corresponding allyl ethers 5, 7, and 10. The key intermediate in this synthesis is the corresponding allylic amines prepared by reaction of allyl ethers with chlorosulfonyl isocyanate.