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Pentacyclic Triterpenoids from Ilex macropoda

  • Kim, Dae-Keun;Nam, Il-Yong;Kim, Jin-Wook;Shin, Tae-Yong;Lim, Jong-Pil
    • Archives of Pharmacal Research
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    • v.25 no.5
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    • pp.617-620
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    • 2002
  • Six compounds were isolated from the twigs of Ilex macropoda. Their structures were elucidated as betulinic acid, lupeol, betulone, betulin, erythrodiol and 11-oxo-erythrodiol by physicochemical and spectroscopic analysis. Among them, lupeol, betulone, erythrodiol and 11-oxo-erythrodiol were isolated for the first time from this plant.

Synthesis and Biological Activity of Annulated Pyrazoles as Selective COX-2 Inhibitors. I.

  • Kim, Hyun-Hee;Park, Jae-Gyu;Moon, Tae-Chul;Chang, Hyun-Wook;Jahng, Yurng-Dong
    • Archives of Pharmacal Research
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    • v.22 no.4
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    • pp.372-379
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    • 1999
  • A series of disubstituted 4,5-polymethylenepyrazoles were synthesized and evaluated their inhibitory activities against COX-2. Some compounds showed strong (0.3 nM) inhibitory activity on COX-2 and were found somewhat selective (up to 16) on COX-2 over COX-1.

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Analgesic and Hypothermic Activities of Melandrin

  • Lee, Eun-Bang;Cheon, Seon-Ah;Lee, Young-Soon;Chung, Ha-Sook;Woo, Won-Sick
    • Archives of Pharmacal Research
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    • v.18 no.1
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    • pp.38-40
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    • 1995
  • melandrin exhibited an analgesic activity as assessed by inhibition of writhing syndromein mice and by pressure method of inflamed paws of arts and inflamed tails of mmice, and showed a hypothermic effect. However, no anti-inflammatory activity was shown.

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Synthesis and In Vitro Cytotoxicity of 1,3-Dioxoindan-2-Carboxylic Acid Arylamides

  • Jung, Jae-Kyung;Ryu, Jin-Hyeong;Yang, Sung-Il;Cho, Jung-Sook;Lee , Hee-Soon
    • Archives of Pharmacal Research
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    • v.27 no.10
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    • pp.997-1000
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    • 2004
  • A series of 1,3-dioxoindan-2-carboxylic acid arylamides were synthesized and evaluated for in vitro cytotoxicity against four human cancer cell lines (HOP62, SK-OV-3, MD-MB-468 and T- 47D). The most active was compound 3e (1.2 ${\mu}M$ against SK-OV-3 cell line) bearing a 4- methyl substituent.

Fusion of Library, Archive, Museum, Publisher (LAMP): the NTNU Library Experience

  • Ke, Hao-Ren
    • Journal of Information Science Theory and Practice
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    • v.4 no.2
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    • pp.66-74
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    • 2016
  • The convergence of libraries, archives, and museums (LAMs) has garnered attention in recent years. Extending the tendency further, National Taiwan Normal University (NTNU) fuses the library, archive, museum, and publisher (LAMP) functionality together in its library. This article elaborates on the LAMP practices of the NTNU Library, which indicates that without creating new units in a university, its library can play a good role of curating invaluable university assets.