• Title/Summary/Keyword: University Archives

Search Result 5,943, Processing Time 0.028 seconds

Organic Reaction Utilizing Cycilic Carbonate I. Polymerization of monochloroethylenecarbonate with phenols

  • Moon, Do-Won
    • Archives of Pharmacal Research
    • /
    • v.8 no.4
    • /
    • pp.191-195
    • /
    • 1985
  • The polymerization of title compound (MCEC, I) with phenols led to give corresponding resole type polymer. Phenol and p-methoxyphenol polymer had a relative higher molecular weight and a property of elastomer, but p-chloro-and p-nitrophenol polymer had a lower ones. Also, phenol and p-meth-oxyphenol gave to crosslinking polymer by elongation of reaction period and rising of temperature.

  • PDF

Hypoglycemic Effects of Eryngium Creticum

  • Jaghabir, Madi
    • Archives of Pharmacal Research
    • /
    • v.14 no.4
    • /
    • pp.295-297
    • /
    • 1991
  • E. creticum has been used in folk medicine in Jordan as a remedy for scorpion stings in the rural areas and as a hypoglycemic agent. The hypoglycemic activity of an aquous decoction of plant arial parts of E. creticum was tested in normoglycemic and streptozocin-hyperglycemic rats. Results indicate that those extract caused significant reductions in blood glucose concentration when given orally.

  • PDF

Facile Synthesis and Biological Evaluation of Heterocyclic Compounds Containing Diazepam

  • Berghot, M.A.
    • Archives of Pharmacal Research
    • /
    • v.24 no.4
    • /
    • pp.263-269
    • /
    • 2001
  • Diazepamoxadiazoles 4,5,6,12,14 and 22 were prepared with the binary form system. Diazepamthiadiazoles 15,20 and Diazepamtriazoles 7,8,9,17,18,19 and 21 were also shapely synthesized. Some of these compounds were screened to test their antibacterial activity against E. coli and B. subtilis compounds 15 and 20 show potent activity against these bacteria.

  • PDF

An improved synthesis of 2'-fluoro-2'-deoxyarabinofuranosyl pyrimidine nucleosides

  • Chun, Moon-Woo
    • Archives of Pharmacal Research
    • /
    • v.6 no.1
    • /
    • pp.79-81
    • /
    • 1983
  • Several potent anti-herpes virus nucleosides, 2'fluoro-2'-deoxyarabinofuranosyl pyrimidine nucleosides, were prepared in good yields by a new condensation method using sodium iodide and a new solvent system, and FMAU could be also prepared directly from thymine by this method.

  • PDF

The radical bromination reaction of ethylenecarbonate

  • Moon, Do-Won
    • Archives of Pharmacal Research
    • /
    • v.6 no.1
    • /
    • pp.1-6
    • /
    • 1983
  • The reaction of ethylenecarbonate (I) with bromine was carried out in the presence of benzolperoxide as radical initiator. The following several different esters being ring opened were obtained; bromoacetyl-bromoformate, (1-hyroxy, 1, 2-dibromo)-ethyl bromoformate, (1-hydroxy, 1, 2, 2'-tribromo)diethylacarbonate, 2-bromoethyl-tribromoacetate, (1-acetoxy, 1'-bromomethyl)-bromomalo nate, 2-bromoethyl-bromoacetoxy-tribromoacetate.

  • PDF

Structure-Activity Relationship Study of Asiatic Acid Derivatives for New Wound Healing Agent

  • Jeong, Byeong-Seon
    • Archives of Pharmacal Research
    • /
    • v.29 no.7
    • /
    • pp.556-562
    • /
    • 2006
  • Ten semi-synthetic derivatives of asiatic acid were prepared and their wound healing effects were evaluated by employing a tensile strength assay and a wound area assay. Among them, ethoxymethyl 2-oxo-3,23-isopropylidene-asiatate (12) showed the strongest and the fastest wound healing activity. Furthermore, it left the smallest scar after healing.

Synthesis of Biologically Active 3-Benzalphthalide Derivatives

  • Ibrahim, Tarek M.
    • Archives of Pharmacal Research
    • /
    • v.14 no.4
    • /
    • pp.342-345
    • /
    • 1991
  • Synthesis of series of 3-benzalphthalidyl-amino acids and their corresponding methyl esters, dipeptides and tripeptide methyl esters 2a-7c is decribed. All 3-benzalphthalidynamino acids 2a-g were found to possess a remarkable antimicrobial properties against a number of microorganisms and fungi.

  • PDF