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Structure-Activity Relationship Study of Asiatic Acid Derivatives for New Wound Healing Agent  

Jeong, Byeong-Seon (College of Pharmacy, Seoul National University)
Publication Information
Archives of Pharmacal Research / v.29, no.7, 2006 , pp. 556-562 More about this Journal
Abstract
Ten semi-synthetic derivatives of asiatic acid were prepared and their wound healing effects were evaluated by employing a tensile strength assay and a wound area assay. Among them, ethoxymethyl 2-oxo-3,23-isopropylidene-asiatate (12) showed the strongest and the fastest wound healing activity. Furthermore, it left the smallest scar after healing.
Keywords
Asiatic acid; SAR; Wound healing;
Citations & Related Records

Times Cited By Web Of Science : 4  (Related Records In Web of Science)
Times Cited By SCOPUS : 3
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