• BMB Reports
• /
• 제33권1호
• /
• pp.92-95
• /
• 2000

The HIV-1 p24(202-221) sequence ETINNEEEWDRVHPV HAGP contains a B-cell epitope with the earliest immune response and the highest antibody titer against anti-mouse sera obtained by immunization with p24 antigens. A novel mouse monoclonal antibody (mAb) was generated against the immunodominant B-cell epitope of the HIV-1 p24 capsid protein, p24(202-221). BALB/c mice were immunized with the four branched multiple antigenic peptide (MAP) containing the HIV-1p24(202-221) sequence, and antibody-secreting hybridoma were produced by fusion of mouse splenocytes with P3X63Ag8.653, mouse myeloma cells. One clone which produced the antigen-specific mAb named KI-24 (Isotype IgG1, light chain: ${\kappa}$) was identified. mAb KI-24 was highly specific for both the p24(202-221) and p24 proteins when analyzed by ELISA and Western blotting. Since p24(202-221) also contains a cytotoxic T-lymphocyte epitope, this specfic peptide epitope and the monoclonal antibody with specific reactivity against the p24 protein and p24(202-221) can be used in peptide vaccine development and p24 antigen detection from HIV patients.

• 한국실내디자인학회논문집
• /
• 제23권1호
• /
• pp.88-95
• /
• 2014

This study intended arousal of other viewpoints that deal with and understand spaces and shapes, by describing the concept of 'dimensions' into visual patterns. Above all, the core concept of spatial dimensions was defined as 'expandability'. Then, first, the 'golden ratio', 'Fibonacci sequence', and 'fractal theory' were defined as elements of each dimension by stage. Second, a 'unit cell' of one dimension as 'minimum unit particles' was set. Next, Fibonacci sequence was set as an extended concept into two dimensions. Expansion into three dimensions was applied to the concept of 'self-similarity repetition' of 'Fractal'. In 'fractal dimension', the concept of 'regularity of irregularity' was set as a core attribute. Plus, Platonic solids were applied as a background concept of the setting of the 'unit cell' from the viewpoint of 'minimum unit particles'. Third, while 'characteristic patterns' which are shown in the courses of 'expansion' of each dimension were embodied for the visual expression forms of dimensions, expansion forms of dimensions are based on the premise of volume, directional nature, and concept of axes. Expressed shapes of each dimension are shown into visually diverse patterns and unexpected formative aspects, along with the expression of relative blank spaces originated from dualism. On the basis of these results, the 'unit cell' that is set as a concept of theoretical factor can be defined as a minimum factor of a basic algorism caused by other purpose. In here, by applying diverse pattern types, the fact that meaning spaces, shapes, and dimensions can be extracted was suggested.

• 한국신재생에너지학회:학술대회논문집
• /
• 한국신재생에너지학회 2005년도 춘계학술대회
• /
• pp.326-329
• /
• 2005

Proton exchange membrane (PEM) should be sufficiently hydrated with proper water management to maintain a good ionic conductivity and performance of a PEM fuel cell. However. cathode flooding resulting from excess water can impede the transport of reactants and hence deteriorate the fuel cell performance. For the PEM fuel cell to be commercially viable as vehicle or portable applications, the flooding on the cathode side should be minimized during the fuel cell operation. In this study, visualization technique was applied to understand the cathode flooding phenomena on the cathode side of a PEM fuel cell. To this end. a transparent PEM unit fuel cell wi th an act ive area of $25cm^2$ was designed and manufactured to allow for the visualization of cathode channel with performance characteristics. Two-phase flow resulting from the electro-chemical reaction of fuel cell was investigated experimentally. The images photographed by CCD camera with cell operating temperatures $(30\~50^{\circ}C)$ were presented. Results indicated that the flooding on the cathode side first occurs near the exit of cathode channel. As the operating temperature of fuel cell increases. it was found that liquid water droplets tend to evaporate easily and it can have an influence on lowering the flooding level. It is expected that this study can effectively contribute to the detailed researches on modeling water transport of an operating PEM fuel cell including two-phase flow phenomena.

• 한국복합재료학회:학술대회논문집
• /
• 한국복합재료학회 2005년도 춘계학술발표대회 논문집
• /
• pp.90-93
• /
• 2005

A thermal model of carbon spun yarn and its composite is presented. Based on voxelization method, the unit cells of spun carbon yam and its composite are divided into a number of volume elements and the local material properties have been given to each element. By using Finite Difference Method, temperature distribution in the unit cell can be obtained. Effective thermal conductivity of unit cell is calculated using the temperature distribution and thermal conductivities of local elements.

• 한국조사연구학회:학술대회논문집
• /
• 한국조사연구학회 2005년도 추계학술대회 발표논문집
• /
• pp.169-183
• /
• 2005

가중치 조정(weighting adjustment)으로 단위 무응답(unit nonresponse)을 처리하는 문제에서 성향점수를 추정하는 모형을 만들기 위해 응답변수와 관심변수를 동시에 고려하는 다변량 회귀나무(multivariate regression tree)기법을 제안하였다. 효과적인 무응답 조정층 구축을 위해 응답한 개체들만 사용하는 경우와 모든 개체들을 사용하는 경우를 제시하고 이 두방법을 편향의 관점으로 비교한다.

• Journal of Electrical Engineering and Technology
• /
• 제11권2호
• /
• pp.463-469
• /
• 2016

In this paper, the use of a dual composite right/left-handed coplanar waveguide (CPW) transmission line is proposed for the design of a band rejection filter. The notch property of the filter is achieved by combining the convex signal line with the shorted concave meander line, and the equivalent circuit model is extracted from the geometry of the unit cell for organizing the band rejection property. Then the equivalent parameters of the unit cell are analyzed to identify those behaviors. And the dispersion characteristics and energy distributions are simulated. In the end, the band rejection filter is manufactured by cascading two proposed unit cells. We show that the measurement result for the resonant frequency demonstrates good agreement with the simulation result and the band rejection filter provides a rejection performance of 17.5 dB at the stopband frequency ranging from 869 MHz to 894 MHz.

• 한국정보디스플레이학회:학술대회논문집
• /
• 한국정보디스플레이학회 2006년도 6th International Meeting on Information Display
• /
• pp.175-177
• /
• 2006

Here we report an enhanced flexoelectric switching in a self-assembled system of smectic liquid crystal and some specific dopant. The assembled unit block seemed to have electric dipole and as a result induces large flexoelectric polarization due to its asymmetric shape and shows fast switching to the electric field. The unit blocks are oriented in a helical fashion in the cell with large gap (${\sim}5{\mu}m$) and shows selective reflection property. In the thin cell (${\sim}2{\mu}m$), the unit blocks are aligned homeotropically on the bare ITO substrate with no surface treatment and shows fast decaying time.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2010년도 제39회 하계학술대회 초록집
• /
• pp.267-267
• /
• 2010

The continuous change in the electronic band structure of metal-adsorbed bilayer graphene was calculated as a function of metal coverage using first-principles calculations. Instead of modifying the unit cell size as a function of metal coverage, the distance between the metal atoms and bilayer graphene in the same $2{\times}2$ unit unit cell was controlled to change the total charges transferred from the metal atoms to bilayer graphene. The validity of the theoretical method was confirmed by reproducing the continuous change in the electronic band structure of K-adsorbed epitaxial bilayer graphene, as shown by Ohta et al. [Science 313, 951 (2006)]. In addition, the changes in the electronic band structures of undoped, n-type, and p-type bilayer graphene were studied schematically as a function of metal coverage using the theoretical method.

• 한국유체기계학회 논문집
• /
• 제15권5호
• /
• pp.20-26
• /
• 2012

An APU(Auxiliary Power Unit) for helicopters has been developed in Korea and tested at the AETF(altitude engine test facility) in KARI(Korea Aerospace Research Institute) for the purpose of the military qualification. A cell correlation test was performed before the official test, and the results are within the tolerance. The APU has the capability of supplying electric power as well as compressed air to the helicopters. It was tested at bleed extraction conditions, electric power extraction conditions, and maximum continuous concurrent power conditions within the entire helicopter flight envelop. Some special test equipments were implemented for the measurement of air flowrate, electric power and so on. The tests were successfully performed and their results satisfy the requirements of the helicopters.

• 한국정보통신학회:학술대회논문집
• /
• 한국정보통신학회 2019년도 춘계학술대회
• /
• pp.521-524
• /
• 2019

The design of photobiological active photosensitizing molecular model for photodynamic therapy has been attracted as a research for the development of cancer treatment, and has been interested in the effective method for cancer treatment and the photosensitizer having more stable wavelength. Furthermore, the development of photosensitizer has been already carried out from the first generation molecule to the third one, and the research of smart photosensitizer as the fourth generation has been requested. As a fact, the selective killing of the only cancer cell is very difficult problem, and the present photodynamic therapy has the problem of killing of the normal cell. So, I have designed the new modelling of photosensitizer having the smart recognizing unit and the magnetic nanoparticle as well as having the several effective recognizing unit. In particular, the new model design of the photosensitizer having lanthanide metal has suggested for the development of photodynamic therapy. The model design of these new photosensitizing molecules will be introduced in the poster section for the new turning point of the development of photosensitizer.