• Journal of Korean Medical classics
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• v.26 no.1
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• pp.27-38
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• 2013

Objective : This article shows that while Seishu Hanaoka(華岡靑洲) is known to have developed an effective anesthetic formula composed of traditional herbs and performed the world first partial mastectomy under a general anesthesia in 1804, anesthetic formulas very similar to those developed by him were widely recorded and deemed used in Japan and Northeast Asia before his invention. The origin of the formulas will be tracked down to compare with the several formulas broadly administered in the region. Methods : Historical literature analysis was adopted to achieve the objective. 1. Mayaku-ku (麻藥考): this book is the main medical classic by Nakagawa Syutei(中川修亭) that introduces Seishu Hanaoka, his anesthetic formulas and mastectomy. 2. Northeast medical classics: Seuideukhyobang (世醫得效方) in 1337, Uibangryuchui (醫方類聚), Uihui(宜彙) and so on. Result : Herbs such as aconitum and datura were applied as a anesthetic agent early on before the Chinese Yuan dynasty. In Korea as well, some old medical books documented such use of those herbs and relevant formulas. Conclusion : Formulas that counted as invented and employed by Seishu Hanaoka as anesthetics, in fact, had been widely known and used in the region before his era. We should pay due attention to his creativity that combined a western surgical intervention and traditional anesthetic agents and successfully performed a newly introduced surgical practice in Japan. The point is that Hanaoka took note of anesthetic herbs or formulas traditionally inherited in North-east Asian medicine and successfully applied them to the surgical procedures for breast cancer, or mastectomy and mammotomy. This history alerts us to neglected or forgotten potentials of traditional medicine in anesthetic treatment and more.

• Water for future
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• v.27 no.1
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• pp.123-131
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• 1994

A plunge pool is often employed as an energy-dissipating device at the end of a spillway or a pipe culvert. A jet from spillways or pipes frequently generates a scour hole which threatens the stability of the hydraulic structure. Existing scour prediction formulas of plunge pool of spillways or pipe culverts give a wide range of scour depths, and it is, therefore, difficult to accurately predict those scour depths. In this study, a new experimental method and new scour prediction formulas under submerged circular jet for large bed materials with shallow tailwater depths were developed. A major variale, which was not used in previous scour prediction equations, was the ratio of jet size to bed material size. In this study, jet momentum acting on a bed particle and jet diffustion theory were employed to derive scour prediction formulas. Four theoretical formulas were suggested for the two regions of jet diffusion, i.e., the region of flow establishment and the region of established flow. The semi-theoretically developed scour prediction formulas showed close agreement with laboratory experiments performed on a movable bed made of large spherical particles.

• YAKHAK HOEJI
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• v.59 no.5
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• pp.235-244
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• 2015

The goal of this study is to help for the utilization the national pharmacists test through the analysis of item development management to the foreign pharmacists examination. The United States is going to NABP (National Association of Boards of Pharmacy) initiative under the curriculum in question on the basis of this assessment and develop standards and unified, systematic system to conduct tests pharmacist. Practice oriented (patient scenario, the participation of a pharmacist or perform work, clinical practice) examination is doing in Canada, The UK is asking the for more than 70 percent and the prescription needed for actual calculation in practice prior to testing program, and by the including that allows references use. Our country may introduce the job as a clinical pharmacist, positively. Item management system is integrated into four regions based on the six-year curriculum should be done in harmony proportion of each region. Integration of fusion of each region in accordance with the duties should be come out. It has gradually been able to item management system developed by the United States or Canada. This item notice pharmacist judging the results of the work must be carried out for management upgrading to a form of management with an emphasis on clinical practice in developed countries. Foundation design, development, production and management and test after actively reviewing ways to improve management system for to management systems, a pharmacist to improve the quality of the national examination could be contributing are involved.

• Journal of the Earthquake Engineering Society of Korea
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• v.8 no.3
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• pp.1-12
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• 2004

Due to the 1989 Loma Prieta, 1995 Hyogoken Nambu earthquakes, etc, a number of bridge columns  were collapsed in flexure-shear failures as a consequence of the premature termination of the column longitudinal reinforcement. Nevertheless, previous researches for the performance of bridge columns were concentrated on the flexural failure mode. It is well understood that the seismic behaviour of RC bridge piers was dependent on the performance of the plastic hinge of RC bridge piers, the ductility of which was desirable to be computed on the basis of the curvature. Experimental investigation was made to evaluate the variation of the curvature of the plastic hinge  region for the seismic performance of earthquake-damaged RC columns in flexure-shear failure mode. Seven test specimens in the aspect ratio of 2.5 were made with test parameters: confinement ratios, lap splices, and retrofitting FRP materials. They were damaged under series of artificial earthquakes that could be compatible in Korean peninsula. Directly after the pseudo-dynamic test, damaged columns were retested under inelastic reversal cyclic loading under a constant axial load, $P=0.1f_{ck}A_g$. Residual seismic capacity of damaged specimens was evaluated by analzying the moment-curvature hysteresis and the curvature ductility. Test results show that the biggest curvature was developed around 15cm above the footing, which induced the column failure. It was observed that RC bridge specimens with lap-spliced longitudinal steels appeared to fail at low curvature ductility but significant improvement was made in the curvature ductility of RC specimens with FRP straps wrapped around the plastic hinge region. Based on the experimental variation of the curvature of RC specimens, new equivalent length of the plastic hinge region was proposed by considering the lateral confinement in this study. The analytical and experimental relationship between the displacement and the curvature ductility were compared based on this proposal, which gave excellent result.

• Journal of the Korea Concrete Institute
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• v.25 no.6
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• pp.631-639
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• 2013

Non-linear finite element analysis for newly developed precast concrete details for beam-to-column connection which can be used in moderate seismic region was carried out in this study. Developed precast system is based on composite structure and which have steel tube in column and steel plate in beam. Improving cracking strength of joint under reversed cyclic loading, joint area was casted with ECC (Engineering Cementitious Composites). Since this newly developed precast system have complex sectional properties and newly developed material, new analysis method should be developed. Using embedded elements and models of non-linear finite element analysis program ABAQUS previously tested specimens were successfully analyzed. Analysis results show comparatively accurate and conservative prediction. Using finite element model, effect of axial load magnitude and flexural strength ratio were investigated. Developed connection have optimized performance under axial load of 10~20% of compressive strength of column. Plastic hinge was successfully developed with flexural strength ratio greater than 1.2.

• Structural Engineering and Mechanics
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• v.24 no.4
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• pp.429-446
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• 2006

Experimental investigation was conducted to evaluate the seismic ductility of earthquake-experienced concrete columns with an aspect ratio of 2.5. Eight circular concrete columns with a diameter of 600 mm were constructed with three test parameters: confinement ratio, lap-splice of longitudinal bars, and retrofitting with Fiber Reinforced Polymer (FRP) materials. The objective of this research is to examine the seismic performance of RC bridge piers subjected to a Quasi static test (QST), which were preliminary tested under a series of artificial earthquake motions referred to as a Pseudo dynamic test (PDT). The seismic enhancement effect of FRP wrap was also investigated on these RC bridge piers. Six specimens were loaded to induce probable damage by four series of artificial earthquakes, which were developed to be compatible with earthquakes in the Korean peninsula by the Korea Highway Corporation (KHC). Directly after the PDT, six earthquake-experienced columns were subjected to inelastic cyclic loading under a constant axial load of $0.1{f_c}^{\prime}A_g$. Two other reference specimens without the PDT were also subjected to similar quasi-static loads. Test results showed that specimens pre-damaged by moderate artificial earthquakes generally demonstrated good residual seismic performance, which was similar to the corresponding reference specimen. Moreover, RC bridge specimens retrofitted with wrapping fiber composites in the potential plastic hinge region exhibited enhanced flexural ductility.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• v.y2005m4
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• pp.405-408
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• 2005

A theoretical analysis is developed for an annular injection type supersonic ejector having a second-throat downstream under the assumption that the Fabri-chocking is placed in mixing chamber. Non-mixing theory is applied to formulate secondary flow pressure in the region between inlet of the mixing chamber and Fabri-chocking. To describe the shock standing at the inlet of the mixing chamber, two dimensional oblique shock relations are used and it is assumed that the shock affects only primary flow at Fabri-chocking plane. In conclusion, it agrees well with experiments in case of small contracting angle of mixing chamber, under 4degrees.

• Nuclear Engineering and Technology
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• v.29 no.2
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• pp.110-126
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• 1997

A two-dimensional continuum model for the hydrogen mining phenomena in the containment subcompartment under severe accident conditions has been developed to predict the spatial distribution of the hydrogen concentration. The model can predict the distribution of time-dependent hydrogen concentration for HEDL experiments well. For the simulation of these experiments, the hydrogen is mixed uniform within the test compartment. To predict the extent of non-uniform distribution, the dominant factors such as the geometrical shape of obstacle and velocity of source injection in mixing phenomena are investigated. If the obstacle disturbing the flow of gas mixture exists in the compartment, the uniform distribution of hydrogen might be not guaranteed. The convective circulation of gas flow is separately formed up and down of the obstacle position, which makes a difference of hydrogen concentration between the upper and lower region of the compartment. The recirculation flow must have a considerable mass flow rate relative to velocity of the source injection to sustain the well-mixed conditions of hydrogen. Finally, in order to account for non-uniform distribution of the hydrogen due to the geometrical configuration the maximum-to-average ratio is functionalized.

• Journal of Microbiology and Biotechnology
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• v.21 no.12
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• pp.1257-1263
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• 2011

This paper is dedicated to the study on the external and internal mass transfers of glucose for succinic acid fermentation under substrate and product inhibitions using a bioreactor with stirred bed of immobilized Actinobacillus succinogenes cells. By means of the substrate mass balance for a single particle of biocatalysts, considering the kinetic model adapted for both inhibitory effects, specific mathematical models were developed for describing the profiles of the substrate concentration in the outer and inner regions of biocatalysts and for estimating the substrate mass flows in the liquid boundary layer surrounding the particle and inside the particle. The values of the mass flows were significantly influenced by the internal diffusion velocity and rate of the biochemical reaction of substrate consumption. These cumulated influences led to the appearance of a biological inactive region near the particle center, its magnitude varying from 0 to 5.3% of the overall volume of particles.

• Elastomers and Composites
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• v.36 no.4
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• pp.255-261
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• 2001

This study was related with the effect of elevated temperature on the tensile strength of edge-cut samples. There was a different tensile strength behavior of uncut samples and pre-cut samples under different test temperatures. Tensile strength of uncut sample decreases with increasing test temperature. When pro-cut size(C) is larger than critical cut size($C_{cr}$), tensile strength or pre-cut specimen at $80^{\circ}C$ is higher than that of pre-cut specimen at room temperature (RT). Test specimens under $80^{\circ}C$ condition exhibited more secondary cracks at the crack tip region compared to room temperature conditions. However, secondary cracks of pre-cut specimens are not clearly developed at $110^{\circ}C$. Differences in tensile strength induced by different test temperature seem to be responsible for the strain-induced crystallization and micro-cracking patterns.