• Natural Product Sciences
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• 제21권3호
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• pp.185-191
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• 2015

Comparative molecular analysis has been frequently adopted for the authentication of herbal medicines as well as the identification of botanical origins. Roots and rhizomes of the family Umbelliferae have been used as traditional herbal medicines to relieve various symptoms such as inflammation, neuralgia and paralysis in countries of East Asia. Since most herbal medicines of the Umbelliferae roots or rhizomes are generally supplied in the form of dried slices, morphological examination does not often provide sufficient evidence to identify the botanical origin. Using species-specific probes developed by the comparative analysis of nrDNA ITS sequences, a DNA chip was developed to identify herbal medicines for 13 species in the Umbelliferae. The developed DNA Chip proves its potential as a rapid, sensitive and effective tool for authenticating herbal medicines in future.

• 한국작물학회지
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• 제42권4호
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• pp.429-434
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• 1997

산형과에 속하는 약용작물의 특성은 분열과로서 두 개의 종자가 형성되고 유관(油管)과 주병 혹은 동병이 현저하게 특이한 모양을 나타내고 있어서 산형과 작물분류 뿐만 아니라 더 나아가서 종자의 특성이 식물분류에 이용되고 있다. 종자의 형태는 장방형, 타원형 그리고 난형이며 종피색은 옅은 노란색에서부터 흑갈색까지 다양하다. 종자의 길이는 2∼7mm 그리고 폭이 2∼5mm이다. 이 중에서 가장 작은 종자인 시호는 그 천립중이 1.7g이고 가장 큰 종자인 당귀는 3.9g이다.

• Plant Resources
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• 제3권1호
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• pp.66-70
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• 2000

Umbelliferae medicinal crops have low germination under natural condition. Special objective of this study is to investigate morphological characteristics of seeds and effects of environmental factors such as light and temperature on their germination and seedling growth in Umbelliferae plants, using them as oriental medicine materials. Fruits of Umbelliferae are bi-partite type and form 2 seeds. Their oil canals and funiculus or carpaphore has apparently specific shape. Seed shape of Buplerum falcatum, Ligusticum acutilobum and Foeniculum vulgare are oblong, Ledeboutiella seseloides, Angelica dahurica, Angelica gigas elliptic, and Ostericum koreanum ovate. Color of seed coats varied from yellow to dark brown. Seed size was 3.2 to 6.9 mm in length, 1.7 to 4.9 mm in width. One thousand-seed weight of Buplerum falcatum was lowest(at 1,660 mg) and Ledebouriella seseloides and Angelica gigas were relatively highest(at 3,970 mg) having larger size than any others. Optimum temperatures for seed germination and seedling growth ranged from 20 to $25^{\circ}C$ and especially temperature at $25^{\circ}C$ improved seed germinations of Ledebouriella seseloides, Angelica dahurica and Ligusticum acutilobum regardless of light condition.

• Archives of Pharmacal Research
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• 제14권1호
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• pp.87-92
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• 1991

In order to evaluate the pharmacological activities of Chinese medicine, nine Umbelliferae plants were selected and their restoring activity against dexamethasone-induced disorders, liver protective activity, antimicrobial activity, anti-inflammatory activity and antimutagenic activity were tested and compared. Angelica dahurica. Angelica acutiloba and Ostericum koreanum showed various activities in these tests at the dose used in this study.

• Archives of Pharmacal Research
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• 제3권2호
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• pp.75-78
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• 1980

Potential antinumor activity of sixteen Korean medicinal plants was tested against leukemia SN 36, murine tomor model. Survival studies by measuring life span indicated that Morus alba (Moraceae), Verbascum phlomoides (Scrophulariaceae), Curcuma longa (Zingbieraceae), Torilis japonica (Umbelliferae), Bupleurum falcatum (Umbelliferae) and Codonopsis pilosula (Campanulaceae) exhibited significant antitumor activity with the dose-schedule employed in the experiment. Methanol (70%) extracts of Platycodon gradiflorum (Campanulaceae), Bupleurum longeradiatum (Umbelliferae) and Asiasarum sieboldii (Aristolochiaceae) showed rather potent toxicity.

• 생약학회지
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• 제2권1호
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• pp.29-34
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• 1971

A comparative study on Angelica and Cnidium, the two genera of Umbelliferae growing in Korea, was carried about the cytology and fertility of pollen. The somatic chromosome number of Umbelliferae was found almost to be 2N=22. Both species of Kang-whal and Chun-gung were found to be in polyploid with different chromosome numbers each other. The pollen fertility among the species of Angelica was high, but Toh-chun-gung was zero percent. The species of Angelica have been generated with pollen fertility, but species of Cnidium with only root or rootlet.

• 약학회지
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• 제41권2호
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• pp.273-276
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• 1997

Ligusticum tenuissimum belongs to Umbelliferae, and its root is generally used in headache, common cold and arthralgia L. We have extracted and isolated butylidene phthal ide, 3-butylidene-4,5-dihydrophthalide of phthalide group and l-limonene, etc. of terpenoid group from the root by ordinary method. In Ligusticum sinense, L. jeholense, L. tenuissimum, L. jeholense var. tenuisectum, and L. officinale etc., the components of cnidilide, ligustilide of phthalide group are common features and specific constituents in genus Ligusticum. Therefore comparing that there is no phthalide group in genus Angelica, we think it is able to classify the difference of genus between Ligusticum and Angelica of Umbelliferae in chemotaxonomy.

• 생약학회지
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• 제23권4호
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• pp.221-224
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• 1992

From the roots of Angelica dahurica Bentham et Hooker(Umbelliferae), three coumarin glycosides have been isolated and identified as skimmin, $8-O-{\beta}-D-glucopyranosyl$ xanthotoxol and $tert.-O-{\beta}-D-glucopyranosyl-heralenol$. $8-O-{\beta}-D-Glucopyranosyl-xanthotoxol$ was isolated for the first time from plant source.

• Natural Product Sciences
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• 제12권3호
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• pp.129-133
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• 2006

Four coumarins (1-4) and one polyacetylene (5) were isolated from the roots of Anglica purpuraefolia Chung (Umbelliferae) through repeated column chromatography. Four coumarins, isoscopoletin (1), oxypeucedanin hydrate (2), arnottinin (3) and isokhellactone (4), and a polyacetylene, (+)-9(Z), 17-octadecadience-12,14-diyne-1,11,16-triol (5), were identified by spectroscopic analysis including two dimensional NMR and mass. These compounds were examined for their anti-complement activity against the classical pathway of the complement system. However, compounds 1-5 were inactive in this assay system.

• Archives of Pharmacal Research
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• 제15권1호
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• pp.73-77
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• 1992

From the roots of Angelica dahurica Bentham et Hooker (Umbelliferae), five coumarin glucosides together with adenosine have been isolated and identified as nodakenin, 3'-hydroxymarmesinin, tert-O-$\beta$-D-glucopyranosyl-byakangelicin, sec-O-$\beta$-D-glucopyranosyl-byakangelicin and scopolin. This is the first report of the occurrence of these compounds in this plant.