• 대한의용생체공학회:의공학회지
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• 제19권3호
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• pp.321-325
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• 1998

일반적으로 현재의 초음파 의료영상시스템에서 지연시간의 계산에 사용하는 음속도는 인체의연조직에서의 평균속도인 1540m/s 의 값을 이용한다. 그러나 사람마다 혹은 매질의 특성에 따라 초음파의 속도가 크게 차이가 나서 고정된 속도를 이용한 집속 지연시간 계산에는 오차가 발생한다. 이는 해상도의 저하를 가져올 뿐만 아니라, 매질의 기하학적인 크기나 거리정보가 필요한, 심장이나 신장의 용적을 계산과 같은 경우에는 큰 오차를 가져온다. 따라서 매질의 속도를 정확히 구하는 것이 해상도 향상의 중요한 관건의 하나임을 알 수가 있다. 본 논문에서는 이를 위해 매질내의 관심영역에서의 밝기를 최대화시켜주는 접속지연시간 프로파일을 구해 매질 내에서의 옴파의 속도를 측정하여 실제 초음파 팬텀에 적응하여 좋은 결과를 얻을 수 있었다.

• 비파괴검사학회지
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• 제32권5호
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• pp.551-563
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• 2012

초음파진단기는 1950년대부터 사용되기 시작했고 그 동안 꾸준한 기술 발전을 통해 현재 대부분의 병원에서 필수불가결한 영상진단장비로 널리 활용되고 있다. 1970년대 초음파진단기에 어레이 프로브가 사용되기 시작한 이래로 전자적 신호처리를 통한 빔포밍 기술이 초음파진단기에 적용되었고, 꾸준히 개선되어 왔다. 빔포밍 기술은 초음파진단기의 해상도를 결정짓는 중요한 신호처리 기술이다. 이 논문에서는 이 빔포밍 기술의 원리부터 최근 동향까지 간략히 소개하고자 한다. 여기에는 어레이 프로브(array probe)를 사용하는 빔포밍의 원리, 기본적 이론, 실제 구현 등이 포함되고, 또 최근 기술 중 합성구경영상(synthetic aperture imaging: SAI), 적응형 빔포밍(adaptive beamforming), 2차원 어레이 프로브를 사용하는 2차원 빔포밍 기술 등의 주제도 소개한다. 이런 다양한 빔포밍 기술들은 다양한 다른 분야의 기술들과 여러 가지 형태로 발전적으로 융합하면서 시스템의 성능을 지속적으로 향상시켜 갈 것이다.

• 대한의용생체공학회:의공학회지
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• 제28권6호
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• pp.803-810
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• 2007

Although synthetic aperture focusing techniques can improve the spatial resolution of ultrasound imaging, they have not been employed in a commercial product because they require a real-time N-channel beamformer with a tremendously increased hardware complexity for simultaneous beamforming along M multiple lines. In this paper, a hardware-efficient beamformer architecture for synthetic aperture focusing is presented. In contrast to the straightforward design using NM delay calculators, the proposed method utilizes only M delay calculators by sharing the same values among the focusing delays which should be calculated at the same time between the N channels for all imaging points along the M scan lines. In general, synthetic aperture beamforming requires M 2-port memories. In the proposed beamformer, the input data for each channel is first upsampled with a 4-fold interpolator and each polyphase component of the interpolator output is stored into a 2-port memory separately, requiring 4M 2-port memories for each channel. By properly limiting the area formed with the synthetic aperture focusing, the input memory buffer can be implemented with only 4 2-port memories and one short multi-port memory.

• Journal of Korean Medical Science
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• 제33권44호
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• pp.279.1-279.16
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• 2018

Magnetic resonance-guided focused ultrasound (MRgFUS) is a new emerging neurosurgical procedure applied in a wide range of clinical fields. It can generate high-intensity energy at the focal zone in deep body areas without requiring incision of soft tissues. Although the effectiveness of the focused ultrasound technique had not been recognized because of the skull being a main barrier in the transmission of acoustic energy, the development of hemispheric distribution of ultrasound transducer phased arrays has solved this issue and enabled the performance of true transcranial procedures. Advanced imaging technologies such as magnetic resonance thermometry could enhance the safety of MRgFUS. The current clinical applications of MRgFUS in neurosurgery involve stereotactic ablative treatments for patients with essential tremor, Parkinson's disease, obsessive-compulsive disorder, major depressive disorder, or neuropathic pain. Other potential treatment candidates being examined in ongoing clinical trials include brain tumors, Alzheimer's disease, and epilepsy, based on MRgFUS abilities of thermal ablation and opening the blood-brain barrier. With the development of ultrasound technology to overcome the limitations, MRgFUS is gradually expanding the therapeutic field for intractable neurological disorders and serving as a trail for a promising future in noninvasive and safe neurosurgical care.

• JSTS:Journal of Semiconductor Technology and Science
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• 제14권5호
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• pp.579-587
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• 2014

This paper presents a variable gain amplifier (VGA) for an analog front-end (AFE) of ultrasound medical imaging. This VGA has a closed-loop topology and shows a 37-dB-linear characteristic with a single-stage amplifier. It consists of an op-amp, a non-binary-weighted capacitor array, and a gain-control block. This non-binary-weighted capacitor array reduces the required number of capacitors and the complexity of the gain-control block. The VGA has been fabricated in a 0.35-mm CMOS process. This work gives the largest gain range of 37 dB per stage, the largest P1 dB of 9.5 dBm at the 3.3-V among the recent VGA circuits available in the literature. The voltage gain is controlled in the range of [-10, 27] dB in a linear-in-dB scale with 16 steps by a 4-bit digital code. The VGA has a bandpass characteristic with a passband of [20 kHz, 8 MHz].

• 대한의용생체공학회:의공학회지
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• 제20권4호
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• pp.503-513
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• 1999

본 논문에서는 일반적인 합성구경기법에 대한 통합 모형을 제시하고 수학적인 해석을 통하여 합성구경 기법들에 대한 초음파 빔패턴의 단일 표현식을 유도하였다. 이 결과를 이용하여 기존의 합성구경 기법들에 대한 성능을 분석하고 비교하였으며, 선형주사 영상에 적합한 새로운 합성구경 기법을 제안하였다. 제안된 방법은 모든 영상점에서 양방향 동적 집속이 가능하며, 이를 실제 영상에 적용하여 의료용 초음파 B-모드 영상의 해상도를 획기적으로 개선할 수 있다. 제안된 방법에 의하여 집속된 초음파 빔패턴은 기존의 방식과 비교하여 주엽의 폭이 절반으로 감소하고 측엽의 크기는 유사하다. 컴퓨터 모사실험을 통하여 본 논문의 해석결과와 제안된 합성구경 기법의 타당성을 검증하였다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2007년도 하계종합학술대회 논문집
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• pp.357-358
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• 2007

Contrast enhancement in the field of ultrasound imaging contributes to improve the accuracy of medical diagnosis by enhancing the visibility of ultrasound images. This paper proposes a contrast enhancement method that improves the contrast of ultrasound images both globally and locally by fusing global and adaptive contrast enhancement methods. Experimental results show that our approach yields more competitive results than the existing global and adaptive contrast enhancement methods in enhancing the visibility of ultrasound images.

• 대한수의학회지
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• 제62권1호
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• pp.2.1-2.5
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• 2022

An 8-year-old spayed female, mixed dog presented multiple, bloody exudative skin lesions on the bilateral flank which spread 1 week after mastectomy for treatment of mammary gland tumor (MGT). Multiple, ill-marginated, irregular, and heterogeneously thickened cutaneous and subcutaneous lesions and enlarged lymph nodes were identified in ultrasound and computed tomography. Histopathological examination confirmed adenocarcinoma with lymphatic invasion presumed to be metastatic MGT. Clinical signs improved after chemotherapy but died after 1 month. This study suggests that cutaneous metastasis be considered for differential diagnosis of cutaneous lesions in dogs with a history of MGT, although skin metastasis from MGT is rare.

• Physical Therapy Rehabilitation Science
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• 제9권1호
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• pp.43-48
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• 2020

Objective: Breast cancer-related lymphedema (BCRL) is a major sequela after surgery or radiotherarpy for breast cancer. Manual lymphatic drainage (MLD) is designed to reduce lymph swelling by facilitating lymphatic drainage. This study attempted to determine the histologic changes in the skin and subcutaneous layer, and the immediate effect of MLD in decreasing lymphedema using ultrasound imaging, which is the method used most commonly to eliminate BCRL. Design: A single-group experimental study. Methods: Five subjects who were diagnosed with hemiparetic upper extremity lymphedema more than six months after breast cancer surgery participated in the study. MLD was performed for 60 minutes in the order of the thorax, breast, axilla, and upper arm of the affected side. In order to determine the effect of MLD, ultrasound imaging and limb volume were assessed. Two measurement tools were used for asessing lymphedema thickness among the pretest, posttest, and 30-minute follow-up period. Results: Significant diferences in ultrasound imaging and upper limb volume were found between the affected side and non-affected side (p<0.05). On the affected side, although ultrasound imaging showed a significant decrease after MLD (p<0.05), there were no significant difference in upper limb volume when compared to the baseline. Conclusions: In this study, a significant decrease in lymphedema by MLD was demonstrated by ultrasound imaging, which is considered to be more useful in assessing histological changes than limb volume measurements. Further research on the protocol for eliminating lymphedema will be needed.

• 대한의용생체공학회:의공학회지
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• 제28권2호
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• pp.294-299
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• 2007

For efficient and accurate diagnosis of ultrasound images, appropriate time gain compensation(TGC) and dynamic range(DR) control of ultrasound echo signals are important. TGC is used for compensating the attenuation of ultrasound echo signals along the depth, and DR controls the image contrast. In recent ultrasound systems, these two factors are automatically set by a system and/or manually adjusted by an operator to obtain the desired image quality on the screen. In this paper, we propose an algorithm to find the optimized parameter values far TGC and DR automatically. In TGC optimization, we determine the degree of attenuation compensation along the depth by dividing an image into vertical strips and reliably estimating the attenuation characteristic of ultrasound signals. For DR optimization, we define a novel cost function by properly using the characteristics of ultrasound images. We obtain experimental results by applying the proposed algorithm to a real ultrasound(US) imaging system. The results verify that the proposed algorithm automatically sets values of TGC and DR in real-time such that the subjective quality of the enhanced ultrasound images may be sufficiently high for efficient and accurate diagnosis.