• 대한치과의사협회지
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• 제54권5호
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• pp.348-355
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• 2016

Ideal autogenous or allogenic bone graft materials should provide 1) stabilization of blood clot, 2) scaffolds for cellular proliferation and differentiation, 3) release of osteogenic growth factors, 4) appropriate resorption profile for remodeling of new bone. Teeth, especially dentin, mostly contain hydroxyapatite and type I collagen which are similar to bone, and could be valuable graft material. Clinically teeth are used as calcined or demineralized forms. Demineralized form of dentin can be more effective as a graft material. But a conventional decalcification method takes time and long treatment time may give negative effects to various osteogenic proteins in dentin. Author used a new clinical method to prepare autogenous teeth, which could be grafted into the removal defects immediately after extraction using vacuum ultrasonic system. The process could be finished within two hours regardless of the form (powder, chip or block). Teeth were processed to graft materials in block, chip, or powder types immediately after extraction. It took 120 minutes to prepare block types and 40 minutes to prepare powder. Clinical cases did not show any adverse response and the healing was favorable. Rapid preparation of autogenous teeth with the vacuum ultrasonic system could make the immediate one-day extraction and graft possible.

• 대한화장품학회지
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• 제48권3호
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• pp.255-264
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• 2022

자생 희귀콩의 한 종류인 납떼기콩(Glycine max landrace)의 활성 성분을 확인하고 이의 친환경적인 추출 방법으로 초음파 추출 방법을 도입하였다. 납떼기콩 추출물에 대한 성분 분석을 통해 기존 일반콩에서는 발견되지 않은 에피카테킨 성분을 확인하였다. 초음파를 활용한 효과적인 추출을 위해 통계학적 분석 방법인 반응 표면 분석법을 이용하여 주요 추출 조건을 최적화를 수행하였다. Box-Behnken design 프로세스를 통해 추출온도, 추출용매/용질의 비율, 추출 시간을 핵심 독립 변수로 하는 15가지 실험이 수행되었다. 두 가지 종속변수인 에피카테킨 함량과 총 이소플라본 함량에 대한 2차 회귀식과 이의 결정 계수는 각각 R² = 0.9939 와 R² = 0.9844로 높게 확인되어 상호 관계가 높은 유의성을 보이는 것으로 확인되었다. 이 두 가지 종속 변수의 최대 기대치를 만족하는 추출 조건은 추출온도 40.4 ℃, 추출용매/용질의 비율 19.3 times 및 추출 시간 91 sec 로 예측되었다. 이에 대한 에피카테킨 함량과 총 이소플라본 함량의 기댓값과 실제 실험값이 유사한 결과로 확인되어 높은 신뢰성이 있는 최적화 모델임을 확인하였다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집A
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• pp.609-615
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• 2001

This study proposes analysis and evaluation method of time series ultrasonic signal using attractor analysis for fusion joint part of polyethylene piping. Quantitatively characteristics of fusion joint part is analysed features extracted from time series. Trajectory changes in the attractor indicated a substantial difference in fractal characteristics. These differences in characteristics of fusion joint part enables the evaluation of unique characteristics of fusion joint part. In quantitative fractal feature extraction, feature values of 4.291 in the case of debonding and 3.694 in the case of bonding were proposed on the basis of fractal dimensions. In quantitative quadrant feature extraction, 1,306 point in the case of bonding(one quadrant) and 1,209 point(one quadrant) in the case of debonding were proposed on the basis of fractal dimensions. Proposed attractor feature extraction can be used for integrity evaluation of polyethylene piping material which is in case of bonding or debonding.

• 한국미생물·생명공학회지
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• 제51권1호
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• pp.43-52
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• 2023

The purpose of this study is to confirm the antioxidant, black hair, and hair growth effects of the N. jatamansi, O. basilicum, and C. sativus mixed extracts that pharmacological efficacy has been verified. Accordingly, four samples (NOC-1 to-4) produced under different extraction conditions were prepared and the results are as follows. First, all samples showed an increase in antioxidant content in a concentration-dependent manner from the results of antioxidant efficacy. In particular, NOC-4 extracted by steaming and ultrasonic methods showed the highest antioxidant effect among the four samples. As a result of analysis of the amount of melanin production in mouse melanoma cells, NOC-4 with concentration of 500 ㎍/ml showed higher melanin production compared to the control group, so the black hair efficacy was the best. Also, in the hair growth test results, it was found that the hair growth was the best at 0.94 ± 0.10 mm at experimental group orally administered with 500 mg/kg of NOC-4. In addition, as a result of cytotoxicity analysis in mouse melanoma cells, the safety of samples was demonstrated by maintaining cell viability of 95% or more at all concentrations. These results suggest that the steaming and ultrasonic extraction method increased the extraction yield of active ingredients for antioxidant, melanin, and hair generation, thereby affecting physiological activity. Based on these results, if the steaming and ultrasonic extraction methods are applied to the mixed extraction of N. jatamansi, O. basilicum, and C. sativus, it is judged that the practical potential as a natural material for black hair and hair growth agents will increase.

• 분석과학
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• 제16권2호
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• pp.134-142
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• 2003

LC-ICP-MS를 이용한 어류중 비소의 종분화 분석을 위해 microwave-assisted extraction과 sonication extraction 방법을 비교하였다. Ultrasonic nebulizer와 cross flow nebulizer를 사용한 비소종들의 검출한계는 유사한 결과를 보였다. 분석된 비소 종들은 arsenobetaine (AsB), arsenite [As(III)], dimethylarsine acid (DMA), monomethylarsonic acid (MMA), arsenate [As(v)] 와 phenylarsonic acid (PAA) 이다. 두 가지 방법은 NRCC (National Research Council of Canada)의 표준물질인 DORM-2를 50% 메탄올로 추출하였다. arsenobetaine의 경우, 두 방법 모두 5% 이하의 상대표준편차와 82% 이상의 추출효율을 보였다. Arsenobetaine은 microwave assisted extraction 방법에서 $14.18{\pm}0.42mg\;kg^{-1}$을 보였고 sonication extraction 방법에서는 $13.54 {\pm}0.84mg\;kg^{-1}$을 보였다. dimethylarsine acid (DMA)의 경우 각각 $0.45{\pm}0.06mg\;kg^{-1}$과 $0.44{\pm}0.06mg\;kg^{-1}$를 보였다.

• Korean Chemical Engineering Research
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• 제54권2호
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• pp.229-233
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• 2016

본 연구에서는 식물세포배양액으로부터 파클리탁셀을 효율적으로 회수하기 위하여 초음파를 이용한 액-액 추출 공정을 개발하였다. 액-액 추출을 위한 최적의 초음파 파워와 조업 시간은 주어진 하층(메틸렌 클로라이드 층)/상층(메탄올 농축액 층) 비(25%, v/v)에서 각각 250W와 15 min임을 알 수 있었다. 최적 조건 하에서 초음파를 이용한 액-액 추출 공정의 경우 단 1 회 추출로 대부분의 파클리탁셀을 하층(메틸렌 클로라이드 층)으로부터 회수(~92%) 가능하였다. 또한 무기염 첨가에 의한 초음파 상승효과로 인하여 액-액 추출을 위하여 적절한 무기염 농도와 초음파 파워가 요구됨을 알 수 있었다.

• 한국정밀공학회지
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• 제15권12호
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• pp.226-235
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• 1998

This study proposes the analysis and evaluation of method of time series of ultrasonic signal using the chaotic feature extraction for ultrasonic pattern recognition. The features are extracted from time series data for analysis of weld defects quantitatively. For this purpose, analysis objectives in this study are fractal dimension, Lyapunov exponent, and strange attractor on hyperspace. The Lyapunov exponent is a measure of rate in which phase space diverges nearby trajectories. Chaotic trajectories have at least one positive Lyapunov exponent, and the fractal dimension appears as a metric space such as the phase space trajectory of a dynamical system. In experiment, fractal(correlation) dimensions and Lyapunov exponents show the mean value of 4.663, and 0.093 relatively in case of learning, while the mean value of 4.926, and 0.090 in case of testing in slag inclusion(weld defects) are shown. Therefore, the proposed chaotic feature extraction can be enhancement of precision rate for ultrasonic pattern recognition in defecting signals of weld zone, such as slag inclusion.

• Smart Structures and Systems
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• 제2권3호
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• pp.253-274
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• 2006

The structural monitoring of multi-wire strands is of importance to prestressed concrete structures and cable-stayed or suspension bridges. This paper addresses the monitoring of strands by ultrasonic guided waves with emphasis on the signal processing and automatic defect classification. The detection of notch-like defects in the strands is based on the reflections of guided waves that are excited and detected by magnetostrictive ultrasonic transducers. The Discrete Wavelet Transform was used to extract damage-sensitive features from the detected signals and to construct a multi-dimensional Damage Index vector. The Damage Index vector was then fed to an Artificial Neural Network to provide the automatic classification of (a) the size of the notch and (b) the location of the notch from the receiving sensor. Following an optimization study of the network, it was determined that five damage-sensitive features provided the best defect classification performance with an overall success rate of 90.8%. It was thus demonstrated that the wavelet-based multidimensional analysis can provide excellent classification performance for notch-type defects in strands.

• 한국정밀공학회지
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• 제15권11호
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• pp.152-165
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• 1998

This study proposes the analysis and evaluation method of time series ultrasonic signal using the chaoral post-process system for precision rate enhancement of ultrasonic pattern recognition. Chaos features extracted from time series data for analysis quantitatively weld defects For this purpose, feature extraction objectives in this study are fractal dimension, Lyapunov exponent, shape of strange attrator. Trajectory changes in the strange attractor indicated that even same type of defects carried substantial difference in chaoticity resulting from distance shifts such as nearby 0.5, 1.0 skip distance. Such difference in chaoticity enables the evaluation of unique features of defects in the weld zone. In quantitative chaos fenture extraction, feature values of 0.835 and 0.823 in the case of slag inclusion and 0.609 and 0.573 in the case of crack were suggested on the basis of fractal dimension and Lyapunov exponent. Proposed chaoral post-process system in this study can enhances precision rate of ultrasonic pattern recognition results from defect signals of weld zone, such as slag inclusion and crack.

• 비파괴검사학회지
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• 제25권3호
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• pp.189-200
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• 2005

Ultrasonic inspection methods are widely used for detecting flaws in materials. One of the more popular methods involves the extraction of an appropriate set of features followed by the use of a neural network for the classification of the signals in the feature space. This paper describes an approach which uses LMS method to determine the coordinates of the ultrasonic probe followed by the use of SAFT to estimate the location of the ultrasonic reflector The method is employed for classifying NDE signals from the steam generator tubes in a nuclear power plant. The classification results using this scheme for the ultrasonic signals from cracks and deposits within steam generator tubes are presented.