• Title/Summary/Keyword: Ulmus macrocarpa

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Effect of Anti-atopic Allergic Reaction in Response to Oriental Herb Extracts (생약재 추출물의 아토피 완화효과)

  • Yang, Hee-Jin;Park, Kye-Won;Kim, Hyun-Suck;Cho, Soo-Muk;Park, Ki-Moon
    • Korean Journal of Food Science and Technology
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    • v.42 no.1
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    • pp.109-114
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    • 2010
  • The in vivo and in vitro effects of oriental herb extracts of Cassia obtusifolia, Taraxacum platycarpum and Ulmusmacrocarpa on anti-atopic allergic reaction were evaluated in this study. A mixture of these extracts exhibited more potent anti-allergic activities in human mast cells than those from individual extracts. The herbal mixture significantly inhibited the release of compound 48/80-induced $\beta$-hexosaminidase release in the human mast cell line, HMC-1. The mixture also suppressed the production of PMA and A23187-induced inflammatory cytokines in HMC-1 cells. To further investigate the in vivo effects of the herbal mixture, a Dermatophagoides farinae (DF)-induced atopic dermatitis mouse model was utilized. Oral administration of the herbal mixture significantly decreased the ear thickness and swelling in DF treated NC/Nga mice in a dose dependent manner. Furthermore, serum levels of IgE and interleukin-4 (IL-4) were significantly decreased, whereas interferon-gamma (IFN-$\gamma$) levels were increased in the mixture administrated groups when compared to the control. Taken together, our data indicate the possibility of using a mixture of the oriental herb extract to relieve symptoms of atopic dermatitis.

Protection and Detoxification Effects of Oriental Herb Extract Mixture on TCDD-Induced Oxidative Stress (TCDD로 유발된 Oxidative Stress에 대한 생약재 추출물의 방어 및 해독효과)

  • Hwang, Jin-Kook;Lee, Kyung-Jin;Yang, Hee-Jin;Park, Ki-Moon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.3
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    • pp.294-301
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    • 2008
  • This study was carried out to investigate the protective effects and detoxification of oriental herb extracts mixture (Saururus chinensis, Taraxacum platycarpum, Ulmus macrocarpa, Glycyrrhiza glabra, Rhynchosia nulubilis) on TCDD-induced oxidative stress. Thirty five male rats were divided into 5 groups: normal control group received saline; vehicle control group received DMSO and acetone; only TCDD-treated group received multiple intraperitoneal injection of TCDD ($100{\mu}g/kg$) and saline; post-treated group of OHEM (400 mg/kg/day) received oral administration for 5 weeks after TCDD treatment; and pre-treated group of OHEM (400 mg/kg/day) received oral administration for 6 weeks from 1 week before TCDD treatment. The elevated serum activities of alanine transaminase (AST), aspartate transaminase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH) and atherorganic index due to TCDD were significantly decreased by the treatment of OHEM (p<0.05); the pre-treatment of OHEM was especially effective. Hydropic lesions and cytoplasmic vacuolizations in the liver of TCDD-treated rats were inhibited by the treatment of OHEM. Also, OHEM treatment reduced edemas in small intestine villus of TCDD-treated rats. These results suggest that OHEM from various oriental herb extracts might be a useful protective and detoxification agent against TCDD.

New Records of Powdery Mildews from Ornamental Trees in Korea (I) (관상수목의 미기록 흰가루병(I))

  • Shin, Hyeon-Dong;Yang, Sung-Il;Lee, Sang-Hyun
    • The Korean Journal of Mycology
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    • v.27 no.2 s.89
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    • pp.158-163
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    • 1999
  • Powdery mildew diseases previously unrecorded in Korea were noticed on four species of ornamental trees. Field observations on each disease were described and the causal fungi were identified. Powdery mildew of Symplocos chinensis for. pilosa was found to occur mildly, especially on plants growing in shade. The causal fungus was identified as Microsphaera nomurae U. Braun. Cornus florida was found to be infected with Microsphaera pulchra Cooke & Peck and supposed to be epidemic in nursery. Powdery mildew of Malus baccata occurred on young leaves and herbaceous stems in nursery. The causal fungus was classified as Podosphaera leucotricha (Ellis & Everh.) Salmon. Powdery mildew of Ulmus macrocarpa was found to occur in autumn and severe on young shoots. Uncinula kenjiana Homma was identified as the causal fungus.

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A Study of the Flora of Kyungpook National University Forests (경북대학교(慶北大學校) 연습림(演習林)의 유관속(維管束) 식물상(植物相)에 관(關)하여)

  • Hong, Sung Cheon;Lee, Byung Cheon
    • Current Research on Agriculture and Life Sciences
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    • v.1
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    • pp.101-111
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    • 1983
  • This experiment was conducted to investigate the flora of Kyungpook National University Forests, which is located in Walme-Ri, Hyundong-Myon, Chungsong-Kun and at $128^{\circ}$ 59' $55^{\prime\prime}-129^{\circ}$ 01' 30"E longitude and $36^{\circ}$ 10' $30^{\prime\prime}-36^{\circ}$ 13' 00"N latitude. The results obtained can be summarized as follows; The kinds of the vascular plants identified are 298 which are composed of 79 families, 188 genera, 248 species, 1 subspecies, 46 varieties and 3 formae. Woody plants are composed of 39 families, 67 genera, 112 species, 7 varieties and 3 formae. The total number of woody plants listed are 122, tall trees of woody plants 50, shrubs 46 and winders 16, respectively. The kinds of edible plants listed are 118 such as Lithospermum erythrohizon, Codonopsis lanceolata and Aster scaber etc. Medical plants are listed as 48 kinds such as Schizandra chinensis, and A canthopanax sessiliflorus etc. Con Codonopsis Schizandra. It is the first time to report that the populations of Ulmusmacrocarpa, Acanthopanax sessiliflorus, Schizandra chinensis, and Lithospermum erythrorhizon are existed in this area.

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Vascular Plants Distributed in the Berchemia berchemiaefolia of Special Protection Zones of Songnisan National Park (속리산국립공원 특별보호구인 망개나무 자생지에 분포하는 관속식물상)

  • Oh, Hyun-Kyung;Kim, Young-Ha;Yun, Sang-Gi
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.20 no.3
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    • pp.33-44
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    • 2017
  • This study investigated in the vascular plants of special protection zones (the native land of Berchemia berchemiaefolia in Sadam-ri and Gallon valley) of Songnisan National Park and identified the whole vascular plants. The numbers of vascular plants were summarized as 273 taxa including 82 families, 182 genera, 236 species, 3 subspecies, 28 varieties and 6 forms. Woody plants were identified as 124 taxa (45.4%) and herbaceous plants as 149 taxa (54.6%). A total of 107 taxa were identified in the area of Sadam-ri, and 246 taxa were found in the Gallon valley. A total of 8 taxa of rare plants were identified, each of which was divided into 1 taxa of endangered (EN; Daphne pseudomezereum var. koreana), 3 taxa of vulnerable (VU; Paeonia japonica, Berchemia berchemiaefolia and Iris minutiaurea), 3 taxa of least concern (LC; Aristolochia contorta, Syringa patula var. kamibayshii and Goodyera schlechtendaliana) and 1 taxa of data deficient (DD; Alangium platanifolium). The Korean endemic plants were 9 taxa (Clematis trichotoma, Thalictrum actaefolium var. brevistylum, Aster koraiensis, Cirsium setidens, etc.). In the specific plants by floristic region were 34 taxa, a degree I were 17 taxa (Chloranthus japonicus, Celastrus stephanotifolius, etc.), 9 taxa of a degree II (Euonymus pauciflorus, Acer triflorum, etc.), 4 taxa of a degree III (Aconitum longecassidatum, Angelica gigas, etc.), 2 taxa of a degree IV (Ulmus macrocarpa and Daphne pseudomezereum var. koreana), 2 taxa of a degree V (Berchemia berchemiaefolia and Alangium platanifolium). The naturalized plants were 5 taxa including Fallopia dumetorum, Trifolium repens, Ailanthus altissima, Oenothera biennis, Erigeron annuus. Naturalization rate (NR) was 1.8% of all 273 taxa of vascular plants and the invasive alien plants were not found. The purpose of this study is to identify the flora that grows in the special protection zones of Songnisan National Park and provide the basic data for the management of the special protection zone in the future.

Community Structure, Phytomass, and Primary Productivity in Thuja orientalis Stands on Limestone Area

  • Kwak, Young-Se;Lee, Choong-Il
    • Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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    • v.3 no.3
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    • pp.189-196
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    • 1999
  • The community structure, phytomass, and primary productivity in Thuja orientalis stands on a limestone area located in Maepo-up, Chungbuk province in Korea were estimated quantitatively. Seven species including a small proportion of Quercus dentata were identified in the tree layer, 26 species including Ulmus macrocarpa in the shrub layer, and 79 species including Carex lnceolata in the herb layer of the Thuja stands. The vertical distribution of the fine root phytomass exhibited a power functional decrease relative to the soil depth. The seasonal changes in the fine root phytomass at a soil depth of 5 cm were closely related to the pecipitation in the study area. The productivity of the stand of stems, branches, leaves, and roots were 10.72, 0.82, 0.45 and 6.46 ton DM. $ha^{-1}$ .$yr^{-1}$, respectively. The Thuja stand had a high foliage(25%) and low rate of production per unit of foliage. The annual turnover rate of the fine roots int he Thuja stand was 6.71 $yr^{-1}$. The net primary production of the overstory including the understory was estimated at 19.48 ton DM.$ha^{-1}$.$yr^{-1}$ including an underground section of 6.46 ton DM.$ha^{-1}$.$yr^{-1}$(33%). The allocation ratio of net production to root was lower in the limestone Thuja communities than at the nearby non-limestone ones, whereas the production efficiency to leaf weight was higher in the limestone communities. These results would seem to indicate that the limited production capacity is due to the calcium toxicity and low availability of iron and phosphorus in a limestone soil with a high pH, calcium, and bicarbonate content with a strategy for survival in a hostile habitat.

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Screening of Stat3 inhibitory effects of Korean herbal medicines in the A549 human lung cancer cell line

  • Park, Jong-Shik;Bang, Ok-Sun;Kim, Jinhee
    • Integrative Medicine Research
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    • v.3 no.2
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    • pp.67-73
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    • 2014
  • Background: The transcription factor signal transducer and activator of transcription 3 (Stat3)is constitutively activated in many human cancers. It promotes tumor cell proliferation,inhibits apoptosis, induces angiogenesis and metastasis, and suppresses antitumor hostimmune responses. Therefore, Stat3 has emerged as a promising molecular target for cancertherapies. In this study, we evaluated the Stat3-suppressive activity of 38 herbal medicinestraditionally used in Korea.Methods: Medicinal herb extracts in 70% ethanol were screened for their ability to suppressStat3 in the A549 human lung cancer cell line. A Stat3-responsive reporter assay system wasused to detect intracellular Stat3 activity in extract-treated cells, and Western blot analyseswere performed to measure the expression profiles of Stat3-regulated proteins.Results: Fifty percent of the 38 extracts possessed at least mild Stat3-suppressive activities(i.e., activity less than 75% of the vehicle control). Ethanol extracts of Bupleurum falcatumL., Taraxacum officinale Weber, Solanum nigrum L., Ulmus macrocarpa Hance, Euonymus alatusSieb., Artemisia capillaris Thunb., and Saururus chinensis (Lour.) Baill inhibited up to 75% of thevehicle control Stat3 activity level. A549 cells treated with these extracts also had reducedBcl-xL, Survivin, c-Myc, and Mcl-1 expression.Conclusion: Many medicinal herbs traditionally used in Korea contain Stat3 activity-suppressing substances. Because of the therapeutic impact of Stat3 inhibition, these resultscould be useful when developing novel cancer therapeutics from medicinal herbs.

Preventive Effect of LS-RUG-com-a Mixture of Rubus crataegifolius, Ulmus macrocarpa, and Gardenia jasminoides-on Gastric Disorders in Animal Models (산딸기, 유백피, 치자 추출물의 임상용 복합제제의 동물 실험모델에서의 위 질환 억제활성)

  • Young Ik Lee;Ahtesham Hussain;Md Aziz Abdur Rahman;Ho Yong Sohn;Hye Jung Yoon;Jin Sook Cho
    • Journal of Life Science
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    • v.33 no.11
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    • pp.923-935
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    • 2023
  • Rubus crataegifolius (RC), Ulmus macrocarpa (UM), and Gardenia jasminoides (GJ) are well-known folk medicines in Asia used to treat various gastrointestinal disturbances. The present study evaluated the gastroprotective effect of LS-RUG-com, a mixture of commercially prepared powders of RC, UM, and GJ with a ratio of 3:1:2(w/w/w) against HCl/ethanol-induced gastritis, indomethacin-induced ulcers, and esophageal reflux-induced esophageal mucosal damage and Helicobacter pylori infections. In addition, TNF-α and IL-1β expressions were also determined and measured in esophageal tissue. As to HCl/ethanol-induced gastritis, the LS-RUG-com treatment at a dose of 150 mg/kg showed a remarkable anti-gastritis effect. Regarding indomethacin-induced gastric ulcers, the LS-RUG-com treatment had a significant anti-gastric ulcer effect. Furthermore, in the gastroesophageal reflux disease (GERD) model experiment, the LS-RUG-com treatment resulted in the histological recovery of stomach damage and mucosal injuries. Furthermore, the LS-RUG-com treatment led to an increase in gastric content pH, an increase in mucus protection, and a decrease in gastric pepsin output with a significant decrease in TNF-α and IL-1β. As to the Helicobacter pylori infected animal model, LS-RUG-com had a notable inhibitory effect on Helicobacter growth. The use of RC, UM, or GJ in isolation or the LS-RUG-com treatment as whole had good effects in terms of anti-oxidation, anti-neutralization, gastric acid secretion inhibition, and anti-lipid peroxidation, which supported the use of natural products as systemic gastric protective agents. Our results suggest that the LS-RUG-com might be a significant systemic gastroprotective agent that could be utilized for the treatment and/or protection from gastric disturbances and related damage.

The Flora in Chungnyeongsan and Seorisan (경기도 축령산과 서리산 일대의 식물상)

  • 이유미;김성식;조동광;정승선
    • Korean Journal of Environment and Ecology
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    • v.16 no.1
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    • pp.104-123
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    • 2002
  • The flora survey on Chungnyeongsan and Seorisan was conducted 6 times from 1998 to 2000.817 taxa such as 112 families 415 genera 688 species 1 subspecies 116 varieties 12 forma were recorded. Dominant species in investigated areas was Quercus mongozica and some deciduous broad-leaved species, such as Quercus sp., Acer sp., Fraxinus sp., Carpinus sp., etc. were codominant species in these areas. Pinus koraiensis and Larix teptozepis plantations were also found in these areas. The 16 taxa of rare plants protected by Forestry Service were found in these areas and among them 10 taxa were new populations which had not been recorded in these areas. Discovery of Erunthis stellata, Aconitum koreanum, Paeonia japonica, Scopotia japonica and Acunthopanax senticosus populations indicate that these areas could be regarded as very important one in a biogeographical aspect. Endemic plants were listed 35 taxa and among them 22 taxa including Corydalis maculata, Ulmus macrocarpa, Scrophutaria horuiensis, Cirsium setidens, etc. were new one. Naturalized plants were listed 39 taxa and among them 30 taxa were new one. Lower naturalized index(NI) and higher urbanized index(UI) were recorded compared to those of neighbored areas. There were many kinds of threatening factors fur the plant resources in survey areas, so it is necessary to limit the number of visitors and to introduce the natural relaxation system.