• 약학회지
• /
• 제28권6호
• /
• pp.299-303
• /
• 1984

In order to eluciate the effect of humidity and organic solvent on the decomposition of carbamide peroxide, the kinetic study was carried out. The carbamide peroxide was prepared from urea and 30%-hydrogen peroxide. The accelerated stability analysis for carbamide peroxide crystal in various relative humidity, and for 10%-carbamide peroxide solution of organic solvents were investigated. Both humidity and temperature were important factors influencing the decomposition rate of carbamide peroxide crystal. The higher the humidity and temperature, the greater was the reaction rate. The breakdown rate of crystal was observed as an apparent zero-order, and was faster than the rate of decomposition in dilute propylene glycol, glycerine or sorbitol solutioos which were measured as an apparent first-order reaction. The more dilute to 10% the organic solvents of 10%-carbamide peroxide, the slower was breakdown rate. It is, therefore, useful in the aspects of stability and economics to substitute solvent of carbamide peroxide topical solution (USP XXI) with 10%-propylene glycol or glycerine instead of anhydrous glycerine.

• 전기학회논문지P
• /
• 제58권3호
• /
• pp.291-296
• /
• 2009

"The Act on Ubiquitous City Construction and etc." stipulates the regulations on the planning, construction and management of the u-City. As its national-level law system is about to take its effects, future new city developments are expected to have its legal basis to be built to meet u-City requirements. Also, it is anticipated that such needs would require much more planning techniques and strategies. In reaction to those upcoming needs, this study is to search for new IT infrastructure construction process of the u-City in reality. It is also to supply with the each step framework to execute the u-City projects in more structuralize and systemize manner. Therefore, with the u-City IT infra construction guide line v1.0, purpose of the establishment of comprehensive IT infrastructure construction process.

• 방송과미디어
• /
• 제14권2호
• /
• pp.113-122
• /
• 2009

RoSE(representation of sensory effects)기술은 A/V미디어에서 제공하는 시청각 효과 이외에 바람/향기/진동 등의 실감효과를 팬/발향기/진동의자 등의 다양한 디바이스와 연동시킴으로써 미디어의 실감효과를 극대화하는 기술이다. 2007년 10월 82차 MPEG회의에 처음 제안된 RoSE프레임워크는 SE(sensory effects), USP(user sensory preferences), SDC(sensory device capabilities), SDCom(sensory device commands)의 표준아이템이 상호 연동하는 시스템 구조를 갖는다. 지난 2월 87차 MPEG로잔(Lausanne)미팅에서는 이들을 현실과 가상을 연결하는 인터페이스 표준을 정하는 MPEG-V(ISO/IEC 23005) 프로젝트의 Part 2(control information)와 Part 3(sensory information)으로 분리 배치하고 오는 7월 89차 런던 미팅에서 CD(committee drait)를 목표로 표준화를 진행하고 있다. 본 논문에서는 XML에 기반한 이들 4개의 표준 아이템 구성을 살펴보고 현재까지 MPEG 에서 진행되어 온 RoSE표준화 과정을 소개한다.

• Advances in Traditional Medicine
• /
• 제7권4호
• /
• pp.441-443
• /
• 2007

A preliminary in vitro acid neutralizing capacity test of twelve traditional Ayurvedic antacids were performed in this study. Five traditional preparations of ash of conch shell, ash of oyster, ash of pearl, limestone, and ash of cowrie showed high acid neutralizing capacity similar to standard antacid combination of $Al(OH)_3\;and\;Mg(OH)_2$. Among these the ash of conch shell found the highest acid neutralizing capacity. The ash of tamarind and ash of Achyranthus aspera showed moderate acid neutralizing capacity. The acid neutralizing capacity of red ochre; ash of iron; mixture of niter, alum and ammonium chloride; saltpeter; and ash of mica found below the USP 23 limit.

• 한국독성학회:학술대회논문집
• /
• 한국독성학회 2002년도 Current Trends in Toxicological Sciences
• /
• pp.117-117
• /
• 2002

Paclitaxel isolated from the pacific yew tree, Taxus brevifolia, is microtuble-stabilizing agent that has a promising anticancer activity against a wide variety of tumors such as ovarian, breast and lung cancers. Because of its poor water solubility, paclitaxel is currently formulated in a mixture of polyoxyethyleneglycerol triricinoleate 35 (Cremophor EL) and dehydrated ethanol USP (1:1 v/v).(omitted)

• 한국정보처리학회:학술대회논문집
• /
• 한국정보처리학회 2001년도 춘계학술발표논문집 (하)
• /
• pp.771-774
• /
• 2001

정보검색에서 가장 많이 사용되는 불리언(Boolean)검색에서는 키워드 일치에 의해서만 검색하는 단점을 가지고 있다. 이를 보완하기 위해 다양한 정보원에서 추출한 관련 용어들을 원질의어에 첨가하여 검색의 효율을 높이기 위한 질의 확장 방법들이 모색되어 왔다. 본 논문에서는 질의 확장을 위하여 사용자가 검색에 사용하였던 질의어들의 연속성을 찾아내어 첨가할 용어를 선택하고 질의 확장을 하는 방법을 제시한다. 사용자가 입력한 질의어의 연속성을 찾아내는 방법으로는 데이터 마이닝 기법중 연관 규칙 탐사 방법을 이용한다. 실험은 현재 구축된 정보통신 기술기준 정도시스템에서 사용자들이 검색한 키워드 정보를 이용하였으며 사용자 검색 패턴(USP) 정보를 이용함으로써 사용자가 검색하고자 하는 질의어와 좀더 연관성 있는 용어로 확장하여 사용자 중심적 결과를 얻을 수 있다.

• Journal of Pharmaceutical Investigation
• /
• 제17권3호
• /
• pp.127-133
• /
• 1987

Dissolution characteristics and urinary excreted amount of commercially available three brands of sulfisoxazole tablets were investigated in order to elucidate the in vitro-in vivo correlations and relative bioavailability in humans. All the tablets tested met the K.P. IV and the USP XXI specifications for tablet weight variation, content uniformity, disintegration and dissolution. The disintegration and dissolution rate constants of sulfisoxazole tablets in pH 2.0 HCl-KCl buffer were reduced more significantly (p<0.05) than those in diluted HCl $(1{\rightarrow}12.5)$ and pH 6.5 phosphate buffer. It seemed to be attributed to the pH dependent solubility of sulfisoxazole. We could see that the relative bioavailability of brand B to sulfisoxazole powder was about 90% and that its value was higher than those of other two brands from the urinary excretion data obtained from eight healthy male volunteers by means of Latin square cross over design. No useful correlation was observed between the in vitro and in vivo studies in this experiment.

• 미생물학회지
• /
• 제28권4호
• /
• pp.318-323
• /
• 1990

The bacterial secondary production was measured at 6 sites of Lake Soyang in October, 1989 by $^{3}$H-thymidine incorporation rate. Verfication for the method of bacterial secondary production measurement showed that $^{3}$H-thymidine incorporated into DNA, RNA and protein by average percentage of 38.45, 42.27 and 20.07%, respectively. THe more increased incoporated $^{3}$H-thymidine, the more increasde DNA fraction, but protein fraction was generally low. Incorporation of rate of /usp 3/H-thymidine. $^{3}$H-leucine into protein correlated with protein fraction of incorporated $^{3}$H-thymidine. Conversion factors were calculated as follows; $1.83*10 ^{20}$ cells/moles of thymidine incorporated/hr and 1.69*10$^{22}$ cells/moles of leucine incorporated/hr.

• Genomics & Informatics
• /
• 제8권3호
• /
• pp.159-163
• /
• 2010

Erythrocyte traits are heritable and indirect indicators of blood diseases caused by erythrocyte, but their genetic factors are largely unknown. So we performed genome-wide association study in 8,842 Korean individuals to identify genetic factors influencing erythrocyte traits. We identified 40 associations for three erythrocyte traits at genome-wide significance levels (p < $1{\times}10^{-6}$). We compared these associated loci with those reported in genome-wide association studies of European and Japanese. Our findings include previously identified loci(HBS1L-MYB, TMPRSS6, USP49 and CCND3) in other studies and novel associations (MRDS1/OFCC1, CSDE1, NRAS and 8 other loci). For example, SNP rs4895440 of HBS1L-MYB intergenic region on chromosome 6q23.3 is one of the most associations influencing erythrocyte traits (p=$8.33{\times}10^{-27}$).

• Journal of Pharmaceutical Investigation
• /
• 제21권2호
• /
• pp.79-84
• /
• 1991

The agar diffustion method using Escherichia coli was investigated for determination of Vitamin $B_{l2}$ instead of turbidimetric method using Lactobacillus leichannii (USP XXII method). The turbidimetric method is difficult to control the test organism and it has complicated procedure. From this study, it was found that the agar diffusion method on the determination of Vitamin $B_{12}$ in pharamaceutical preparation is simple and convenient as compared with turbidimetric method. Also we found that the coefficient of variation in reproducibility and the standard error in recovery were 2.18% and 1.83%, respectively.