• 제목/요약/키워드: UPS Function

검색결과 116건 처리시간 0.02초

Clinical Effectiveness of Ultrasound-guided Costotransverse Joint Injection in Thoracic Back Pain Patients

  • Yoon, Kyung Bong;Kim, Shin Hyung;Park, Sang Jun;Moon, Ji Ae;Yoon, Duck Mi
    • The Korean Journal of Pain
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    • 제29권3호
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    • pp.197-201
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    • 2016
  • Because of its anatomical location and function, the costotransverse (CTRV) joint can be a source of thoracic back pain. In this retrospective observational study, we evaluated the clinical effectiveness of the CTRV joint injection in thoracic back pain patients with suspected CTRV joint problems. We enrolled 20 thoracic back pain patients with localized tenderness that was provoked by the application of pressure on the affected CTRV joints. We injected it with 0.5 ml of a ropivacaine and triamcinolone mixture at each level. The mean pre-injection pain score decreased by 37.9% ($7.2{\pm}1.5$ to $4.5{\pm}1.7$, P < 0.001) two weeks after CTRV joint injection. In addition, 70% of patients reported an excellent or good level of satisfaction. We demonstrated that an ultrasound-guided injection of the CTRV joint reduced patients' pain scores and led to a high level of satisfaction at short-term follow-ups in patients with suspected CTRV joint problems.

Expression of HERC4 in Lung Cancer and its Correlation with Clinicopathological Parameters

  • Zeng, Wen-Li;Chen, Yao-Wu;Zhou, Hui;Zhou, Jue-Yu;Wei, Min;Shi, Rong
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권2호
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    • pp.513-517
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    • 2015
  • Background: Growing evidence suggests that the members of the ubiquitin-proteasome system (UPS) are important for tumorigenesis. HERC4, one component, is a recently identified ubiqutin ligase. However, the expression level and function role of HERC4 in lung cancer remain unknown. Our objective was to investigate any correlation between HERC4 and development of lung cancer and its clinical significance. Materials and Methods: To determine HERC4 expression in lung cancer, an immunohistochemistry analysis of a tissue microarray containing samples of 10 lung normal tissues, 15 pulmonary neuroendocrine carcinomas, 45 squamous epithelial cancers and 50 adenocarcinomas was conducted. Receiver operating characteristic (ROC) curve analysis was applied to obtain a cut-off point of 52.5%, above which the expression of HERC4 was regarded as "positive". Results: On the basis of ROC curve analysis, positive expression of HERC4 was detected in 0/10 (0.0%) of lung normal tissues, in 4/15 (26.7%) of pulmonary neuroendocrine carcinomas, in 13/45 (28.9%) of squamous epithelial cancers and in 19/50 (38.0%) of adenocarcinomas. It showed that lung tumors expressed more HERC4 protein than adjacent normal tissues (${\chi}^2$=4.675, p=0.031). Furthermore, HERC4 positive expression had positive correlation with pT status (${\chi}^2$=44.894, p=0.000), pN status (${\chi}^2$=43.628, p=0.000), histological grade (${\chi}^2$=7.083, p=0.029) and clinical stage (${\chi}^2$=72.484, p=0.000), but not age (${\chi}^2$=0.910, p=0.340). Conclusions: Our analysis suggested that HERC4 is likely to be a diagnostic biomarker for lung cancer.

고압 전기화상에 의한 수부 손상 시 비골동맥 천공지 유리피판술을 이용한 재건 (Reconstruction of Hand Using Peroneal Perforator Free Flap in High-Voltage Electrical Burn Patients)

  • 김동훈;유중석;임준규;이동락
    • Archives of Plastic Surgery
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    • 제35권1호
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    • pp.67-72
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    • 2008
  • Purpose: The hand is frequently affected area in high voltage electrical burn injury as an input or output sites. Electrical burn affecting the hand may produce full thickness necrosis of the skin and damage deep structures beneath the eschar, affecting the tendon, nerve, vessel, even bone which result in serious dysfunction of the hand. As promising methods for the reconstruction of the hand defects in electrical burn patients, we have used the peroneal perforator free flaps. Methods: From March 2005 to June 2006, we applied peroneal perforator free flap to five patients with high tension electrical burn in the hand. Vascular pedicle ranged from 4cm to 5cm and flap size was from $4{\times}2.5cm$ to $7{\times}4cm$. Donor site was closed primarily.Results: All flaps survived completely. There was no need to sacrifice any main artery in the lower leg, and there was minimal morbidity at donor site. During the follow-ups, we got satisfactory results both in hand function and in aesthetic aspects.Conclusion: The peroneal perforator flap is a very thin, pliable flap with minimal donor site morbidity and is suitable for the reconstruction of small and medium sized wound defect, especially hand with electrical burn injury.

삼초(三焦)와 영위(營衛)의 상관성(相關性) (The Relation of Three Burning Space And Nutrient & Defensive Qi)

  • 문성식;강정수
    • 혜화의학회지
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    • 제9권1호
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    • pp.105-112
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    • 2000
  • Three burning space concentrating mainly on the text of ${\ll}NeiChing{\gg}$, we got this conclusion by looking at a longitudial perspective of three burning space function, nutrient & defensive qi creation, movement and numbers. 1. Longitudial movement is the law of the universe, by looking at oriental medicine by the thought of heaven and man unity we can tell that longitudial movement concept is used to analyze the physiology of our body. And we can look at our body in a cubic movement suck as top and bottom, left and right, outside and inside, internal and external, upward and downward movement. 2. In Nei Ching the concept of three burning space is seperated in to four different types of three burning space which are three burning space as a fu, three burning space as a water metabolism and excretion organ, and three burning space by its position. 3. nutrient & defensive qi's movement in the channel is the same as the twelve regular channels movement in our body, nutrient qi circulates the yang part twenty five during the day and circulates the ying part twenty five times during the night. Since channel functions corresponds with the sun, moon, and the stars the ups and downs of nutrient & defensive qi's property varies with the difference of the periods. 4. By comparing nutrient & defensive qi's production and property with three burning space's positional property, we can see that three burning space's positional property comes out from the longitudial movement of nutrient & defensive qi.

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NAFTA의 ISD 분쟁사례를 통한 한미 FTA의 ISD 시사점 및 대응방안 (A Study on Preparation for ISD under the KORUS FTA -Lessons Learned from NAFTA ISD Cases-)

  • 배성호
    • 통상정보연구
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    • 제14권2호
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    • pp.369-387
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    • 2012
  • 한미 FTA의 협상 과정에서부터 비준을 걸쳐 발효된 이후까지 끊이지 않는 논쟁의 중심에는 바로 투자자-국가 소송제도인 ISD가 있다. ISD의 본 취지인 외국인 투자자에 대한 보호기능은 국제통상환경에서 없어서는 안 될 보호장치이며 지금까지 수많은 양자투자협정(BIT)에도 적용되어온 제도임에도 ISD에 대한 부정적인 시각은 여전히 존재한다. 그중에서도 가장 큰 우려는 정부의 공공정책이 ISD 때문에 제한될 수 있다는 것이다. 실제로 한미 FTA의 당사국인 미국이 맺은 NAFTA의 경우를 보면 ISD로 인하여 캐나다와 멕시코 정부가 ISD 제소를 당해왔으며, 그로 인하여 공공정책을 추진하면서 제약을 느껴온 것은 사실이다. 그러나 일부의 ISD 사건에서는 일국 정부의 공공정책이 투자자의 이익을 우선한다는 판정부의 결정도 있었다. 그렇다면 한미 FTA가 막 발효된 이 시점에서 우리가 앞으로 일어날 수 있는 우리 정부에 대한 미국기업이나 미국인 투자자의 ISD 제소에 어떻게 대비해야 하며, 정부의 공공정책이 어떻게 해야 ISD 제소의 표적이 되지 아니할지에 대한 분석이 필요하다. 이러한 분석에 가장 효과적인 자료가 미국이 당사국으로 있는 NAFTA의 ISD 사건들이다. NAFTA의 ISD 사건 분석은 판정부가 판정을 함에 있어 어떠한 법리적 해석을 하는지를 알 수 있는 근거자료이며 나아가 우리의 상황에 적용하여 대비하는데 필수적인 도구이기도 하다.

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RTK-GPS와 TS를 이용한 도로선형분석 및 GSIS 구축 (The Analysis of Road Alignement and Construction GSIS Using RTK GPS and TS)

  • 장상규;홍순헌;김가야
    • 한국측량학회지
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    • 제21권4호
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    • pp.293-299
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    • 2003
  • 미래의 도로설계는 첨단정보이용에 편리하고, 자동차 항법체계에 맞추어 차량유도기능을 극대화할 수 있는 선형설계가 필요하다. 따라서 기존 도로의 도로개량설계를 위해서 도로선형에 대한 정회한 분석이 필요하며, 도로설계도와 주요점의 좌표가 필요하게 된다. 본 연구에서는 도로 선형에 대한 정확한 분석을 실시하기 위해서 RTK-GPS로 정보를 획득하였고 토탈 스테이션과 비교 검증하였다 이를 바탕으로 설계좌표와 RTK-CPS 좌표를 비교하여 그 정확도를 평가하였다. 또한 GSIS 개념의 3차원 시각정보를 통해 고도의 변화율, 경사도, 사면의 요철형태를 분석하였다. 마지막으로 토탈스테이션과의 비교로 토공량 산정에서의 비교 고찰도 병행하였다.

만성 치주염을 동반한 파킨슨병 환자의 전악 보철 수복 증례 (Full mouth rehabilitation for a Parkinson's diseases patient with chronic periodontitis: a case report)

  • 고은솔;김종진;백진;차현석;이주희
    • 구강회복응용과학지
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    • 제35권4호
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    • pp.228-234
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    • 2019
  • 파킨슨병은 떨림, 느려진 움직임, 근육의 경직, 자세 불안정성, 보행장애 등의 특징을 나타내는 신경변성 질환으로 도파민과 같은 신경전달 물질이 고갈되어 생긴다. 이러한 파킨슨병의 특성으로 인해 환자들은 협조적으로 치과 치료를 받는 것이 어렵다. 본 증례에서는 만성 치주염이 있는 47세의 파킨슨병 환자에게 고정성 보철 및 임플란트 식립을 통한 전악구강수복을 시행하였고 기능적, 심미적으로 만족할만한 결과를 얻을 수 있었다. 손 조작능력의 저하와 같은 파킨슨병의 특성을 고려하여 짧은 간격의 주기적인 내원을 통한 관리가 필요할 것이다.

각도와 거리 설정에 따른 출판 만화 연출의 특징 (Charicteristics of directing a publishing cartoon according to an angel and a distance setting)

  • 정규하;김소원
    • 만화애니메이션 연구
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    • 통권25호
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    • pp.87-108
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    • 2011
  • 출판만화는 드라마, 영화 등과 함께 대중적 인기를 얻고 있는 매체로서 인정받고 있고 나름의 확립된 장르적 특성이 있다. 그러나 연출에 대한 연구는 영화, 드라마, 연극 등의 다중 매체에 비해 매우 미진한 상태이다. 본 연구는 안수철의 각도와 거리개념을 적용하여 기본적인 연출의 요소 중에서 각도와 거리의 설정에 중점을 두어 분석하고 분류해봄으로써 이론적으로 분류된 기능들이 실제적으로 그러한 기능을 실행하는지 살펴보고 그 외 부가적으로 고려되어야 할 점을 중점적으로 분석해 보고자 한다. 우선 각도와 거리설정은 장르별 만화의 분위기에 따라 특정 설정이 빈도가 높게 나타나리라는 예상으로 접근을 시도했지만 예상과 달리 장르의 특징보다 작가 개인적 기호에 따라 달리 나타나고 있으며 각도와 거리설정의 기능적 측면은 표현적 공간에 국한된 설정이며 강렬함을 표현하는 기능으로 우선시 되어야 하는 것은 물리적 공간의 설정이다. 이러한 만화연출의 특성을 분석해 봄으로써 만화연출의 폭을 넓혀보고자 한다.

Arthroscopic release in adhesive capsulitis of the shoulder: a retrospective study with 2 to 6 years of follow-up

  • Mardani-Kivi, Mohsen;Hashemi-Motlagh, Keyvan;Darabipour, Zohre
    • Clinics in Shoulder and Elbow
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    • 제24권3호
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    • pp.172-177
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    • 2021
  • Background: This study aimed to evaluate the response rate to arthroscopic release treatment in adhesive capsulitis of the shoulder (ACS) for patients with refractory to conservative treatment. Methods: In this retrospective study, 51 patients (age mean, 49.1±5.6 years) with unilateral adherent capsule underwent arthroscopic releasing surgery for the shoulder capsule. Etiologies of the ACS in 30 patients were idiopathic: 10 patients were affected after surgery and 11 patients following trauma. The patients were evaluated in terms of shoulder function, satisfaction rate, pain intensity, and joint range of motion (ROM) based on a Constant score, a Simple Shoulder Test, the visual analog scale, and four movements, respectively. Results: The mean Constant score before surgery was 48.2±3.5 and reached 74.4±6 and 77.0±6.3 at 6 months and the final follow-up, respectively (p<0.001). The mean scores of pain intensity, a Simple Shoulder Test, and ROM showed significant improvement at all follow-ups (p<0.001). Sex, age, and diabetes did not have any significant effect on patient recovery. However, patients who experienced ACS after surgery had poorer results than others at all follow-up points. Conclusions: Arthroscopic releasing surgery of the shoulder in patients with ACS refractory to conservative treatment produces rare complications and an effective injury response. It seems that patients suffering ACS following surgery have a weaker response to the treatment.

산업보건서비스체계의 효율적 관리방안에 관한 연구 (A Study on Reforming the Occupational Health Care System is Korea)

  • 문옥륜;한동운;최병순;최재욱;하은희;이기효;장동민
    • 보건행정학회지
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    • 제4권1호
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    • pp.138-175
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    • 1994
  • The objectives of this study are (i) to review current situations and problems of the occupational health care system with emphasis on reforming the organizations and services, (ii) to find out a disirable occupational health system model based on integration of the occupational health system and the general health system, and finally, (iii) to suggest policy implications in occupational health services in the light of objectives of the newly emerging national health insurance reform in Korea. The major policy implications of this study are as follows: 1. In the long-run, within the occupational health system, preventive occupational health services such as employees' physical check-up, working environment examination, etc should financially be integrated with industrial accident compensation insurance. Currently separately paying expenses for each different category of services by the owner of an enterprise should be disbursed once through the payment of contributions of industrial accident compensation insurance. And then, it is necessary to strengthen and expand the role and function of industrial accident compensation insurance to cover preventive occupational health services. 2. The occupational health system should be integrated with general health system for its effective management. For the short-term policy, it is necessary to eliminate fiscal and access barrier between industrial accident compensation insurance and national health insurance by means of ex post facto settlement of accounts. The duplication of employees' physical check- ups between under the health insurance program and under the industrial health services must be coordinated in a manner either through mutual authorization by the two parties concerned or through merge into the health insurance. 3. The intent of current employees' physical check-up system focused on detection of occupational diseases, should be converted to an idea of medical surveillance system or biological moritoring system. The introduction of medical surveillance or biological monitoring system is a necessary condition to build a positive, effective and inexpensive occupational health care system.

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