• 제목/요약/키워드: U-Value

검색결과 2,052건 처리시간 0.031초

한국산 새빨간검둥이 Neorhodomela aculeata 추출물의 피부세균에 대한 항균활성 (Antimicrobial Activity of Neorhodomela aculeata Extracts Against Human Skin Pathogens)

  • 이지희;이기훈;유현일;주효리;김영식;최한길;남기완
    • 한국수산과학회지
    • /
    • 제39권3호
    • /
    • pp.292-296
    • /
    • 2006
  • The antimicrobial activity of methanol extracts from 17 seaweeds was screened using a paper disc method and using three human skin pathogens: Staphylococcus aureus, S. epidermidis and Candia albicans. The serial extraction of Neorhodomela aculeata was also conducted using four different solvents (n-hexane, chloroform, ethyl acetate, and methanol) and the minimal inhibitory concentration (MIC) of each extract was examined for the three pathogens. Of the 17 seaweeds, the MeOH extracts of Ulva conglobata, N. aculeata and Symphyocladia latiuscula showed antimicrobial activities. For the extracts from N. aculeata and S. latiuscula, the inhibition zones were more than 10 mm in diameter against S. aureus and S. epidermidis, and >7mm for C. albicans. The inhibition zone of U. conglobata treatment was about 8 mm for S. aureus only. The MIC of each N. aculeata extract ranged from 8 to 32 mg/mL against the three human skin pathogens, and the lowest value (8 mg/mL was with the methanol extract. These results suggest that the MeOH extract of N. aculeata might be useful for developing new antibiotics against human skin pathogens.

Production of Chlorphenesin Galactoside by Whole Cells of ${\beta}$-Galactosidase-Containing Escherichia coli

  • Lee, Sang-Eun;Lee, Hyang-Yeol;Jung, Kyung-Hwan
    • Journal of Microbiology and Biotechnology
    • /
    • 제23권6호
    • /
    • pp.826-832
    • /
    • 2013
  • We investigated the transgalactosylation reaction of chlorphenesin (CPN) using ${\beta}$-galactosidase (${\beta}$-gal)-containing Escherichia coli (E. coli) cells, in which galactose from lactose was transferred to CPN. The optimal CPN concentration for CPN galactoside (CPN-G) synthesis was observed at 40 mM under the conditions that lactose and ${\beta}$-gal (as E. coli cells) were 400 g/l and 4.8 U/ml, respectively, and the pH and temperature were 7.0 and $40^{\circ}C$, respectively. The time-course profile of CPN-G synthesis under these optimal conditions showed that CPN-G synthesis from 40 mM CPN reached a maximum of about 27 mM at 12 h. This value corresponded to an about 67% conversion of CPN to CPN-G, which was 4.47-5.36-fold higher than values in previous reports. In addition, we demonstrated by thin-layer chromatography to detect the sugar moiety that galactose was mainly transferred from lactose to CPN. Liquid chromatography-mass spectrometry revealed that CPN-G and CPN-GG (CPN galactoside, which accepted two galactose molecules) were definitively identified as the synthesized products using ${\beta}$-gal-containing E. coli cells. In particular, because we did not use purified ${\beta}$-gal, our ${\beta}$-gal-containing E. coli cells might be practical and cost-effective for enzymatically synthesizing CPN-G. It is expected that the use of ${\beta}$-gal-containing E. coli will be extended to galactose derivatization of other drugs to improve their functionality.

민국시기 중국 여성들의 인체미 의식에 대한 연구 -푸뉘자즈(부녀잡지(婦女雜誌))와 링롱(영롱(玲瓏))을 중심으로- (A Study on the Aesthetics of Women's Body in the Chinese Republican Period -Focused on Women's Magazines, Funüzazhi & Linglong-)

  • 이순재
    • 한국의류학회지
    • /
    • 제37권3호
    • /
    • pp.357-370
    • /
    • 2013
  • The Republican Period of China (1912 to 1949) was when the archetypes of thought (constituting contemporary China) engaged in heated rivalry and were directly influenced by Korea through frequent exchanges. This study analyzes the characteristic of Chinese women's aesthetics towards the human body with a focus on visual materials (such as articles and illustrations concerning hairstyle, makeup, skincare, fashion, and gymnastics) featured in the Chinese women magazines of Fun$\ddot{u}$zazhi (婦女雜誌) and Linglong (玲瓏). This study analyzes these magazines and compares them with Korean counterparts. The movement of the developed and controlled human body was a common characteristic of this period; however, compared to the Chinese, the Japanese colonial period of Korea resulted in an introspective self-examination through excessively objectified eyes. Dress and adornment as the symbol of a new civilization acted as the most remarkable signifier. The overlapping of a western image with a Japanese image led to more resistance in Korea. The criterion for the value of a women's external appearance (that traditionally dualized womanly virtues) collapsed and dress was accepted as an expression of individuality instead of as a social class. The human body was traditionally recognized as a microcosm of the universe that dominated the natural principle of Yin-Yang and the Five Elements. However, the ideal human body was postulated and the aesthetic consciousness of the body changed into an imaginary view of the human body that proceeded to keep the body fit for and gave birth to the concept of supplementing the deficiency of the beauty of the human body with dress and makeup.

기계의 움직이는 정서에 대한 조형 연구 (The animated soul of the machine The development of kinetic elements in installation art, eastern and western positions)

  • 베른트 할프헤르;최한준
    • 만화애니메이션 연구
    • /
    • 통권49호
    • /
    • pp.537-561
    • /
    • 2017
  • 기계나 로봇은 인류의 실존적인 기반에 질문을 던진다. 기계들은 인간의 사고방식에 영향을 주었으며, 사회철학과 가치체계까지 변화시켜왔다. 이와 동시에 기계들은 줄곧 다양하고, 매력적인 특징들을 함유해왔다. 기계기술의 발전은 인류의 발전이라는 상징적 의미와 동시에 인간 존재를 위협하는 위험성이라는 상징적 의미를 함께 가지고 있다. 이러한 기계의 양가적인 특징들을 현대조각의 키네틱 요소에서도 발견할 수 있다. 필자는 조각적인 작품 중에서도 기계나 기계의 메커니즘을 활용하는 조각에 초점을 맞추었다. 이를 역사적인 발전과정을 통해 검토하였으며, 현대미술의 특정 예시들을 당대의 대표 모델로 논하였다. 본 연구는 키네틱아트와 설치미술 분야에서 두각을 나타내는 두 명의 젊은 동시대 작가인, 최우람(Choe u-ram)과 예페 하인(Jeppe Hein)을 대표모델로 선정하였다. 두 작가는 기계나 기계의 메커니즘을 사용하는 동양과 서양의 작가로서, 두 작가의 표현방식의 차이가 존재한다. 예시로 몇 가지 작품을 제시하고, 비교를 통하여 두 작가의 문화적 차이와 시각 언어의 차이가 나타나는 이유에 대하여 분석하였으며, 이를 바탕으로 글로벌화된 세계에서도 지역적 특징이 항상 남아있음을 결론으로 제시한다.

환경오염원인 납의 신경독성에 대한 NMDA 수용체 길항제의 보호 효과 (Protective Effect of NMDA Receptor Antagonist on the Neurotoxicity Induced by Lead as an Environmental Pollutant)

  • 손영우;임요섭;서영미
    • 한국산업보건학회지
    • /
    • 제27권3호
    • /
    • pp.193-200
    • /
    • 2017
  • Objectives: This study was performed to evaluate the neurototoxicity of the environmental pollutant lead acetate(LA) and the protective effect of the D-2-amino-5-phosphonovaleric acid(APV), N-methyl-D-aspartate(NMDA) receptor antagonist on LA-induced cytotoxicity in cultured C6 glioma cells. Materials and Methods: For this study, cell viability in cultured C6 glioma cells was assessed by XTT assay and antioxidative effect, such as lactate dehydrogenase(LDH) activity, by LDH detection kit. Results: LA significantly decreased cell viability in a dose-dependent manner, and the XTT50 value was determined to be 33.3 uM of LA. The cytotoxicity of LA was deemed highly toxic according to Borenfreund and Puerner's toxic criteria. The vitamin E antioxidant significantly increased cell viability damaged by LA-induced cytotoxicity in these cultures. For the protective effect of APV on LA-induced cytotoxicity, APV significantly increased not only cell viability, but also inhibition of LDH activity. From these results, it is suggested that oxidative stress is involved in the neurotoxicity of LA, and APV effectively protected against LA-induced cytotoxicity via an antioxidative effect as an inhibotory activity of LDH. Conclusions: Natural resources like APV may be putative therapeutic agents for the toxic diminution of environmental pollutants such as LA correlated with oxidative stress.

MCNPX 시뮬레이션을 이용한 무납 방사선 차폐 시트 기반의 공간산란 저감화 평가 (Evaluating the Reduction of Spatial Scattering based on Lead-free Radiation Shielding Sheet using MCNPX Simulation)

  • 양승우;박금별;허예지;박지군
    • 한국방사선학회논문지
    • /
    • 제14권4호
    • /
    • pp.367-373
    • /
    • 2020
  • 물체와 X선의 상호작용로 발생하는 산란선으로 야기되는 공간 산란선량은 대부분이 저에너지 영역의 전자기파로 인체에 비교적 쉽게 흡수되어 방사선 피폭정도가 증가하게 된다. 이러한 공간 산란 선량은 방사선작업 종사자 및 환자의 방사선 피폭 정도 지표로도 사용되고 있으며 간접적으로 발생하는 공간 산란 선량을 줄여 피폭을 저감화하기 위한 방안의 필요성이 마련될 필요성이 있다. 이에 본 연구에서는 공간산란 선량을 저감화 방안으로 무납 방사선 차폐 시트를 제시하였고 가슴 X선 촬영검사를 기준으로 몬테카를로(MC; Monte Carlo) 시뮬레이션을 수행하여 거리 변화에 따른 갑상샘과 생식선 위치에서 흡수되는 산란선의 흡수선량을 산출하였고 실측치와 차폐율을 비교 평가하였다.

남한강수계 저수기 수질변동 특성에 관한 연구 (Investigation on Water Quality Variation Characteristics during Dry Season in Namhan River Drainage Basin)

  • 이형진;공동수;김상훈;신기식;박지형;김병익;김성미;장승현;천세억
    • 한국물환경학회지
    • /
    • 제23권6호
    • /
    • pp.889-896
    • /
    • 2007
  • From the direct outflow of Chungju Dam to the junction of water body and watershed in Paldang lake is the scope of this research. This study performed to investigate the main cause of water quality deterioration and the influenced region in the middle field range of the Namhan river Basin with the onsite measurement of water quality and flow rate simultaneously during spring dry season. The purpose of this study is to find out the time-spatial variation characteristics of water quality and flow rate. Following the flow direction $BOD_5$ and $COD_{Mn}$ concentration increased to the highest value of 3.7 mg/L, 5.9 mg/L at Wolgesa respectively. Chl.a concentration increased to $50mg/m^3$ or so at Kangsang, after that it decreased to $37mg/m^3$ at the junction of Paldang lake. Organic matter concentration variation trend showed similar than that of Chl.a. Also $BOD_5$ concentration tendency was similar to Chl.a in every measuring sites except Paldang lake mixing zone. The major factors of water quality deterioration in Namhan river and Paldang lake during dry season were algal bloom and followed internal production. High phosphorus load from Dalcheon and Seom river caused dry season algal bloom and internal production in transitional zone which was stagnant area in downstream of Namhan river.

In situ 법에 의한 Cu-Nb3Sn 복합재료선재의 초전도특성과 이에 미치는 Ti의 영향(I) (Superconducting Properties of in situ Formed Multifilamentary Cu - Nb3Sn Composites and the Effects of Ti Addition on the Superconducting Properties (I))

  • 박현순;서수정;이은덕;안재민
    • 열처리공학회지
    • /
    • 제6권1호
    • /
    • pp.17-25
    • /
    • 1993
  • The Cu - $Nb_3Sn$ composites wire as a superconducting material was prepared by in situ method as follow: Cu - 15wt.% Nb alloys which were melted in a high -frequency induction furnace and casted in bar were cold-worked up to the final diameter of 0.24 mm, electroplated with Sn, pre-treated in two steps and then diffused at $550{\sim}650^{\circ}C$ for 24 ~ 96 hrs. The overall $J_c$ and $T_c$ of the specimens were measured by the four point-probe method at 10 K in the magnetic field of 0 Tesla. The overall $J_c$ of the composites wire which diffused at $550^{\circ}C$ after pre-treating in two steps were generally higher than those of the wire at either $600^{\circ}C$ or $650^{\circ}C$. For the specimens diffused at $550^{\circ}C$, the overall $J_c$ were increased until 72 hrs. of diffusion time and then decreased. However, in case of diffusion at $600^{\circ}C$ and $650^{\circ}C$, the overall $J_c$ were gradually decreased from the beginning. The maximum overall $J_c$ obtained in this experiment was $1.3{\times}10^4\;A/cm^2$, which was measured for the specimen diffused at $550^{\circ}C$ for 72 hrs. When the specimens were diffused at $550^{\circ}C$ for 72 hrs, after pre-treating, the measured critical temperature, $T_c$ was 16.19 K. Similar $T_c$ value were obtained in other specimens regardless of diffusion time and temperature.

  • PDF

UV Laser Rayleigh Scattering을 이용한 $C_3H_8/O_2$ 화염에서 가스 성분의 농도 및 온도 분포 계측에 관한 실험적 연구 (Am Experimental Study on Measurement of Number Density and Temperature Distributions in $C_3H_8/O_2$ Flame by UV Laser Rayleigh Scattering)

  • 진성호;남기중;김회산;장래각;박승한;김웅;박경석;김경수
    • 한국자동차공학회논문집
    • /
    • 제5권2호
    • /
    • pp.60-68
    • /
    • 1997
  • Rayleigh Scattering Cross Sections($\sigma$i) of various gases and the temperature distributions of premixes C3H8/O2 flame are measured by high power KrF(248nm) Exci- mer laser and ICCD camera. Results show that $\sigma$i of O2 and Propane(C3H8) gases agree well in the 5% error range, but of H2 has the more or less difference from the calcul- ated value by other groups. This is attributed to the low RS signal of H2 to Nosie level(S/N ratio). The temperature distributions of flame range out between 300K in the air and about 2000K in the burned area. In this temperature range, out system has the about 250K temperature resolution. Because low RS signals in the reaction area with high temperature are affected highly by noises, temperature uncertainty of this area is relatively high to another part of flame. Experimental results show that UV Rayleigh Scattering can be used for the measurement of mixing ratio of mixed gases and the temperature distributions of flame. Especially, this technique can be applied for the measurement of the mixing ratio of air/fuel before the ignition and the flame structure after the ignition inside the Engine.

  • PDF

일차원적 비균일 개구변조가 광학계 MTF에 미치는 영향 (One dimensional inhomogeneous aperture modulation effects on the MTF of optical system)

  • 홍경희
    • 한국광학회지
    • /
    • 제9권2호
    • /
    • pp.59-62
    • /
    • 1998
  • 일차원적 비균일 진폭변조가 광학계 MTF에 미치는 영향을 조사하였다. 시험평가 렌즈는 국산 유효경 10 mm, 초점거리 87.8 mm인 이중렌즈를 택하였다. 시험렌즈의 수차특성은 축상과 시계각 1.deg.와 2.deg.인 비축에 대해 각각 ray-fan과 파면수차를 계산하여 그림으로 도시하였다. 진폭변조는 시험렌즈 앞에 근접하여 진폭변조판을 위치함으로 이루어진다. 진폭변조판은 계단식으로 투과도가 다른 것과 선형적으로 투과도가 변하는 것을 사용하였다. 진폭변조하지 않았을 때 60 cycles/milimeter(c/mm)의 공간주파수에서 최대 MTF값을 가지는 상평면을 최적 상평면으로 결정하였다. 진폭변조의 경우와 변조하지 않은 경우에 대하여 MTF를 측정해서 그 값을 서로 비교하였다. 축상에서는 변조할 경우 MTF값이 변조하지 않은 경우에 비해 약간 저조하나 축외에서 변조할 경우에는 MTF 값이 시계각이 클수록 많이 증진되었다.

  • PDF