• Journal of Korean Neurosurgical Society
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• v.59 no.2
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• pp.172-181
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• 2016

To describe the details of the foraminoplastic superior vertebral notch approach (FSVNA) with reamers in percutaneous endoscopic lumbar discectomy (PELD) and to demonstrate the clinical outcomes in limited indications of PELD. Retrospective data were collected from 64 patients who underwent PELD with FSVNA from August 2012 to April 2014. Inclusion criteria were high grade migrated disc, high canal compromised disc, and disc protrusion combined with foraminal stenosis. The clinical outcomes were assessed using by the visual analogue scale (VAS), Oswestry Disability Index (ODI) and modified MacNab criteria. Complications related to the surgery were reviewed. The procedure used a unique approach, using the superior vertebral notch as the target and performing foraminoplasty with only reamers under C-arm control. The mean age of the 55 female and 32 male patients was 52.73 years. The mean F/U period was $12.2{\pm}4.2$ months. Preoperative VAS ($8.24{\pm}1.25$) and ODI ($67.8{\pm}15.4$) score improved significantly at the last follow-up (VAS, $1.93{\pm}1.78$; ODI, $17.14{\pm}15.7$). Based on the modified MacNab criteria, excellent or good results were obtained in 95.3% of the patients. Postoperative transient dysthesia (n=2) and reoperation (n=1) due to recurred disc were reported. PELD with FSVNA could be a good method for treating lumbar disc herniation. This procedure may offer safe and efficacious results, especially in the relatively limited indications for PELD.

• Journal of Biomedical Engineering Research
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• v.41 no.2
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• pp.94-100
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• 2020

The purpose of this study was to present the models for classifying the wrist X-ray images by types and for segmenting the radius automatically in each image using deep learning and to verify the learned models. The data were a total of 904 wrist X-rays with the distal radius fracture, consisting of 472 anteroposterior (AP) and 432 lateral images. The learning model was the ResNet50 model for AP/lateral image classification, and the U-Net model for segmentation of the radius. In the model for AP/lateral image classification, 100.0% was showed in precision, recall, and F1 score and area under curve (AUC) was 1.0. The model for segmentation of the radius showed an accuracy of 99.46%, a sensitivity of 89.68%, a specificity of 99.72%, and a Dice similarity coefficient of 90.05% in AP images and an accuracy of 99.37%, a sensitivity of 88.65%, a specificity of 99.69%, and a Dice similarity coefficient of 86.05% in lateral images. The model for AP/lateral classification and the segmentation model of the radius learned through deep learning showed favorable performances to expect clinical application.

• Journal of Korean Academy of Nursing
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• v.48 no.1
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• pp.1-11
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• 2018

Purpose: The purpose of this study was to examine the effects of aromatherapy on stress responses, autonomic nervous system (ANS) activity, and blood pressure in patients hospitalized to receive coronary angiography (CAG). Methods: A non-equivalent control group with a pretest-posttest design was used. The subjects were patients admitted to the day angiography room to receive CAG at E University Hospital (34 in the experimental group and 30 in the control group). The experimental group treatment was inhalation of the aroma oil blended with lavender, ylang-ylang, and neroli at a ratio of 4:2:1 twice before and after CAG. The measurements of stress index, ANS activity, and blood pressure were performed 5 times as follows: at admission, at pre-CAG after treatment I, at post-CAG, 2 hours after treatment II, and 4 hours after treatment II. The data were analyzed using the Mann-Whitney U Test and repeated-measures analysis of variance. Results: Significant interactions in the high frequency of ANS (F=5.58, p=.005) were observed between group and time. Stress index (z=2.14, p=.016), systolic blood pressure (z=4.14, p<.005), and diastolic blood pressure (z=3.28, p=.001) were significantly different between the experimental and control groups after 4 hours of treatment II. Conclusion: The findings showed that aromatherapy was not effective before CAG, but was effective after CAG. Therefore, aromatherapy can be used as a nursing intervention for patients receiving CAG.

• Restorative Dentistry and Endodontics
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• v.41 no.3
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• pp.167-175
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• 2016

Objectives: Endodontically treated teeth with insufficient tooth structure are often restored with esthetic restorations. This study evaluated the cytotoxicity and biological effects of yttria partially stabilized zirconia (Y-TZP) blocks in combination with several dental cements. Materials and Methods: Pairs of zirconia cylinders with medium alone or cemented with three types of dental cement including RelyX U200 (3M ESPE), FujiCEM 2 (GC), and Panavia F 2.0 (Kuraray) were incubated in medium for 14 days. The cytotoxicity of each supernatant was determined using 3-(4,5-dimethylthiazole- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays on L929 fibroblasts and MC3T3-E1 osteoblasts. The levels of interleukin-6 (IL-6) mRNA were evaluated by reverse transcription polymerase chain reaction (RT-PCR), and IL-6 protein was evaluated by enzyme-linked immunosorbent assays (ELISA). The data were analyzed using one-way ANOVA and Tukey post-hoc tests. A p < 0.05 was considered statistically significant. Results: The MTT assays showed that MC3T3-E1 osteoblasts were more susceptible to dental cements than L929 fibroblasts. The resin based dental cements increased IL-6 expression in L929 cells, but reduced IL-6 expression in MC3T3-E1 cells. Conclusions: Zirconia alone or blocks cemented with dental cement showed acceptable biocompatibilities. The results showed resin-modified glass-ionomer based cement less produced inflammatory cytokines than other self-adhesive resin-based cements. Furthermore, osteoblasts were more susceptible than fibroblasts to the biological effects of dental cement.

• Asian-Australasian Journal of Animal Sciences
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• v.12 no.1
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• pp.5-8
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• 1999

Weight records from birth to calving and calving scores of 407 two-year old heifers and weights of their offspring from birth to one year of age were used to study the effects of sire birth weight on maternal traits of their female progeny. The heifers ($G_1$) were Ihe progeny of 81 sires ($G_0$) and were classified into three classes based on their sires' birth weights (High, Medium and Low). The heifers were from three distinct breed-groups and were mated to bulls with medium birth weights within each breed-group to produce the second generation ($G_2$). The data were analyzed using a covariance model. The female progeny of high birth-weight sires were heavier from birth to calving than those sired by medium and low birth-weight bulls. The effect of sire birth weight on calving difficulty scores of their female progeny was not significant. Grand progeny (G2) of low birth-weight sires were lighter at birth than those from high birth-weight sires (p < 0.05) but they did not differ significantly in weaning and yearling weights from the other two Grand progeny groups. The results indicated that using low birth weight sires would not result in an increase in the incidence of dystocia among their female progeny calving at two-year of age and would not have an adverse effect On weaning and yearling weights of their grand progeny.

• Journal of Plant Biotechnology
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• v.35 no.4
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• pp.265-274
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• 2008

Glutathione S-transferases (GSTs) are multifunctional proteins encoded by a large gene family divided into Phi, Tau, Theta, Zeta, Lambda and DHAR classes on the basis of sequence identity. The Phi(F) and Tau(U) classes are plant-specific and ubiquitous. Their roles have been defined as herbicide detoxification and responses to biotic and abiotic stresses. Fifty-two members of the GST super-family were identified in the Arabidopsis thaliana genome, 13 members of which belong to the Phi class of GSTs (AtGSTFs). Based on the sequence similarities of AtGSTFs, 11 BAC clones were identified from Brassica rapa. Seven unique sequences of ORFs designated the Phi class candidates of GST derived from B. rapa (BrGSTFs) were detected from these 11 BAC clones by blast search and sequence alignment. Some of BrGSTFs were present in the same BAC clones indicating that BrGSTFs could also be clustered as usual in plant. They were mapped on B. rapa linkage group 2, 3, 9 and 10 and their nucleotide and amino acid sequences were highly similar to those of AtGSTFs. In addition, in silico analysis of BrGSTFs using Korea Brassica Genome Project 24K oligochip and microarray database for cold, salt and drought stresses revealed 15 unigenes to be highly similar to AtGSTFs and six of these were identical to one of BrGSTFs identified in the BAC clones indicating their expression. The sequences of BrGSTFs and unigenes identified in this study will facilitate further studies to apply GST genes to medical and agriculture purposes.

• Koreanishche Zeitschrift fur Deutsche Sprachwissenschaft
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• v.2
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• pp.101-128
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• 2000

In der vorliegenden Arbeit wurde der Realisierungsmechanismus der fakultativen $Erg\"{a}nzung$ aufgrund des zweidimensionalen Valenzmodells und des zweistufigen Semantikmodlells behandelt. Dabei wurde die $Fakultativit\"{a}t\;der\;Erg\"{a}nzung$ nicht als ein $Ph\"{a}nomen$ im Lexikon angesehen, sondern als ein $Ph\"{a}nomen$ auf der Ebene der Valenzrealisierung, das als Resultat des Zusammenspiels von valenzunabhangigen Faktoren zu betrachten ist. In der bisherigen Valenzforschung wurde die $Fakultativit\"{a}t\;als\;eine\;ausschlie{\ss}lich$ idiosynkratische Eigenschaft des einzelnen Verbs interpretiert, die man bei jedem Verb erlernen $mu{\ss}$. Gegen diese Auffassung wandte die vorliegende Arbeit ein, dass die $Fakultativit\"{a}t$ keine unvoraussagbare idiosynkratische Eigenschaft des einzelnen Verbs ist: Die $Fakultativit\"{a}t\;der\;Erg\;"{a}nzung$ kann durch $Regularit\"{a}ten$ allgemein vorausgesagt werden. Anhand der statischen Lokalisierungsverben im Deutschen wurde gezeigt, dass die $Fakultativit\"{a}t\;der\;lokalen\;Erg\;"{a}nzung$ von den konzeptuellen Prozessen $abh\"{a}ngt:$ Bei dem $Lokalisierungsproze{\ss}$ ist die Realisierung der lokalen $Erg\"{a}nzung$ notwendig. Dagegen ist die Realisierung der lokalen $Erg\"{a}nzung$ bei dem $Delokalisierungsproze{\ss}$ optional. Wenn man die $Fakultativit\"{a}t$ durch allgemeine $Regularit\"{a}ten\;erkl\"{a}ren$ kann, dann ist es nicht $n\"{o}tig,\;die\;Fakultativit\"{a}t$ bei jedem Verb im Lexikon zu markieren. Dadurch kann das mentale Lexikon enorm entlastet werden. Dies bedeutet $f\"{u}r$ deutschlernende $Ausl\"{a}nder$ eine $gro{\ss}e$ Erleichterung.

• Advances in Traditional Medicine
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• v.10 no.1
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• pp.13-20
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• 2010

The leaves of Madhuca (M.) indica J.f.Gmel. (Sapotaceae) have been used traditionally in folk medicine due to its astringent properties and are effective in treatment of eczema and snake bites. Methanolic extract of M. indica is rich in tannins and has been proven experimentally to possess antibacterial activity. The present study was undertaken to evaluate the anti-ulcer and antioxidant activity of M. indica in rats. The methanolic extract of leaves of M. indica was tested at various doses (75, 150 and 300 mg/kg, p.o.) for its effect on gastric secretion and gastric ulcers in pylorus-ligation and on ethanol- induced gastric mucosal injury in rats. The significant reduction in ulcer index in both the models along with an increase in the pH of the gastric fluid and mucin content of stomach, and the acid secretory parameters such as total acidity and volume of gastric fluid were also significantly reduced along with reduction in the pepsin activity in pylorusligated rats proved the anti-ulcer activity of M. indica. The increase in the levels of superoxide dismutase, catalase and reduced glutathione and decrease in lipid peroxidation in both the models proved the antioxidant activity of M. indica. Thus it can be concluded that M. indica possesses anti-ulcer activity, which can be attributed to its antioxidant mechanism of action.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.4
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• pp.111-122
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• 2007

Purpose: The purpose of this study is to make clear the difference of the mental state between formal menstruation group and menorragia group. Methods: The patients suffering from uterine myoma or adenomyosis answered about menstruation and did a blood test and MMPI. They were analyzed by Mann-Whitney U-test. Results: The D scale of complain of a menorrhagia group is higher than normal menstruation group. (p<0.05) According to blood test, The F scale of anemia group is higher than normal group.(p<0.05) The D scale of menorrhagia with anemia group is higher than normal menstruation without anemia group. (p<0.05) The MMPI score of complain of a menorrhagia group, anemia group, and menorrhagia with anemia group showed 1-2 profile type. The MMPI score of normal menstruation group, normal result of the blood test group, and menorrhagia with anemia group showed 1-3 profile type. Conclusion: regardless of the rxistence of anemia, the group with menorrhagia tends to show a state of depression than the control group.

• Proceedings of the Korean Society of Developmental Biology Conference
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• 2003.10a
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• pp.129-129
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• 2003

번식효율이 높은 우수한 후보종빈돈의 조기선발기술을 개발하기 위해 후보종빈돈의 첫발정일령과 첫수정일령에 미치는 요인을 분석한 결과는 다음과 같다. 본 시험에 공시된 후보종빈돈은 충남 천안시에 위치하고 있는 양돈장에서 자돈을 생산ㆍ육성하여 체중 80~90kg에서 선발하였고, 체중이 약 110kg 도달하였을 때 최종 선발하여 이용하였으며, 사양관리는 양돈장의 관행에 따라 실시하였다. 첫발정조사는 생후 22주령때 부터 매일 아침, 저녁으로 2회씩 외음부의 충혈과 부종상태를 관찰하고 승가허용 자세유지 등을 통하여 발정여부를 조사하였다. 교배는 첫발정발견 후 2차 발정이 발현되었을 때 실시하는 것을 원칙으로 하였다. 첫발정 및 첫수정시에 등지방측정기(Lean-meater; Renco, U.S.A.)를 이용하여 제 10늑골의 정중선으로부터 좌측 또는 우측으로 약 5cm 이격된 지점을 2회 측정하여 평균치로 하였다. 후보종빈돈의 품종별 첫발정일령과 첫수정일령은 랜드레이스종이 171.91일과 202.18일, 요크셔종은 178.56일과 208.39일, 랜드레이스종과 요크셔종의 F$_1$은 190.20일과 213.60일로 랜드레이스종이 첫발정일령과 첫수정일령이 가장 빨랐으나 품종간 첫수정일령에 대한 유의적인 차이는 없었다. 출생계절별 첫발정일령 및 첫수정일령은 봄에 출생한 후보종빈돈은 194.14일 및 222.05일, 여름에 출생한 후보종빈돈은 163.25일 및 193.00일, 가을에 출생한 후보종빈돈은 160.25일 및 199.20일, 겨울에 출생한 후보종빈돈은 159.72일 및 190.11일로 봄에 출생한 후보종빈돈의 첫발정일령 및 첫수정일령이 겨울, 가을, 여름에 출생한 후보종빈돈보다 유의적으로 늦게 나타났다(P〈0.01). 등지방두께가 13~16mm인 후보종빈돈의 첫발정일령 및 첫수정일령은 180.32일 및 211.12일, 17~20mm인 후보종빈돈은 172.24일 및 202.43일, 21~23mm인 후보종빈돈은 162.20일 및 195.43일로 등지방두께가 얇을수록 첫발정일령 및 첫수정일령이 지연되었으나 유의적인 차이는 인정되지 않았다.