• 대한방사선기술학회지:방사선기술과학
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• 제44권5호
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• pp.489-494
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• 2021

In this study, radioactivity quantitative analysis was performed on radon contained in cigarette, and the effective dose was calculated using the result value to determine the amount of exposure caused by smoking. A total of 5 types of cigarettes were sampled. Cigarette smoke was collected by using activated carbon, and tobacco were measured by homogenizing for quantitative analysis. For each sample, Bi-214 and Pb-214 were subjected to gamma nuclide analysis to observe the uranium-based radioactive material contained in cigarette, and a measurement time of 30,000 seconds was set for the sample based on the results of previous studies. As a result of measuring the radioactivity of tobacco, a maximum of 0.715 Bq/kg was derived, and in the case of cigarette smoke measured using activated carbon, a maximum of 3.652 Bq/kg was derived. Using this measurement, the average effective dose to the lungs is 0.938 mSv/y, and it was found that there is a possibility of receiving exposure up to 1.099 mSv/y depending on the type of tobacco. It was found that the exposure dose due to cigarette occupies a large proportion of the annual effective dose limit for the general public. Therefore, more diverse studies on radioactive substances in cigarette are needed, and measures to monitor and reduce the incidental exposure to radon should be established.

• Journal of Preventive Medicine and Public Health
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• 제49권3호
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• pp.143-152
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• 2016

Objectives: Metabolic syndrome is a cluster of risk factors for type 2 diabetes mellitus and cardiovascular disease. Associations between metabolic syndrome and several types of cancer have recently been documented. Methods: We analyzed the sample cohort data from the Korean National Health Insurance Service from 2002, with a follow-up period extending to 2013. The cohort data included 99 565 individuals who participated in the health examination program and whose data were therefore present in the cohort database. The metabolic risk profile of each participant was assessed based on obesity, high serum glucose and total cholesterol levels, and high blood pressure. The occurrence of cancer was identified using Korean National Health Insurance claims data. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards models, adjusting for age group, smoking status, alcohol intake, and regular exercise. Results: A total of 5937 cases of cancer occurred during a mean follow-up period of 10.4 years. In men with a high-risk metabolic profile, the risk of colon cancer was elevated (HR, 1.40; 95% CI, 1.14 to 1.71). In women, a high-risk metabolic profile was associated with a significantly increased risk of gallbladder and biliary tract cancer (HR, 2.05; 95% CI, 1.24 to 3.42). Non-significantly increased risks were observed in men for pharynx, larynx, rectum, and kidney cancer, and in women for colon, liver, breast, and ovarian cancer. Conclusions: The findings of this study support the previously suggested association between metabolic syndrome and the risk of several cancers. A high-risk metabolic profile may be an important risk factor for colon cancer in Korean men and gallbladder and biliary tract cancer in Korean women.

• 기본간호학회지
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• 제8권3호
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• pp.302-313
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• 2001

Purpose: To identify characteristics of chronic fatigue, difference between the duration of fatigue and characteristics of chronic fatigue, and association between chronic fatigue and related factors in adults. Method: The subjects for this study were 180 adults who had experienced fatigue for over one month The measurement tools were the Revised Fatigue Scale by Chalder et al. (1993), the Visual Analogue Scale-energy developed by Lee et al. (1991), the BEPSI (Brief Encounter Psychosocial Instrument) by Frank & Zyzanski (1988), Zung's self rating depression scale (1965) and life style items including exercise sleep, drinking smoking and diet as developed by the researchers. Results : Those who complained of fatigue over six months experienced higher disturbances in their daily life compared to those who had suffered from fatigue less than six months. There were a significant correlation between severity of fatigue and depression (r=.46, p<.001), stress (r=.41, p<.001), and sleep (r=.20, p<.01) Statistically significant relationships were found between severity of fatigue and amount of exercise per week (F=3.79. p<.05) disturbed sleep (t=-2.66, p<.01), number of times awakened during the night (F=3.48, p<.05) types of drinking (F=2.65, p<.05), and diet regularity (F=5.83, p<.01). The construction of a multiple regression model revealed an adjusted $R^2$ of .27 with the depression score serving the major predictor variables for severity of fatigue. Men and people in the younger age group were more energetic than women and those in other age groups. Also married people experienced more fatigue than people who were single. divorced or separated. Conclusion: In nursing interventions for fatigue, medical personnel should consider sociodemographic characteristics of the clients, ways to reduce of stress and counter disturbances in daily life and develop strategies for a health promoting life style.

• 대한두경부종양학회지
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• 제25권1호
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• pp.28-32
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• 2009

Background : The most frequently reported risk factors for head and neck suamous cell carcinoma are smoking and alcohol. But in a recent overview, human papilloma virus(HPV) infection was revealed the important carcinogenic factor in oropharyngeal cancer. We aimed to clarify whether HPV directly effects on the oncogenesis and biologic behavior of hean and neck squamous cell carcinoma by comparison with infection prevalence, and physical status of virus. Material and Method : We used HPV genotyping DNA chip(Biocore, Korea, Seoul) arrayed by multiple oligonucleotide probes of L1 sequence of 26 types of HPV and HPV genotypes are identified by fluorescence scanner. The copy numbers of HPV E2 and E6 open reading frames(ORF) were assessed using a TaqMan-based 5'-exonuclease quantitative real-time PCR assay. The ratio of E2 to E6 copy numbers was calculated to determine the physical status of HPV-16 viral gene. Results : We observed a significant difference in HPV prevalence between tonsillar cancer group and control group(73.1% vs. 11.6%), and most of the HPVs were type 16(87.2%) and integrated(94.1%) state. In terms of oral tongue cancer, we demonstrate that 30.5% has integrated HPV-16 in cancer tissue. But Glottic cancer only 1% is related to HPV-16 integration. Conclusion : This study revealed significant relationship of HPV prevalence with oropharyngeal and oral tongue squamous cell carcinoma. Most of HPV were 16 type and integrated or mixed, HPV-16 integration could be directly related to the carcinogenesis.

• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1497-1500
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• 2014

Cervical cancer continues to be an important public health problem in Thailand. While the high risk human papillomavirus (HPV) types have been established as the principle causative agent of both malignancies and the precursor lesions, cervical intraepithelial neoplasia (CIN), other factors may also be involved like other sexually transmitted diseases, as well as smoking. Chlamydia trachomatis is an obligate intracellular Gramnegative bacterium which has a tendency to cause chronic infection featuring inflammation and therefore might be expected to increase the risk of cervical cancer. In the present nested case-control study, 61 cases of cervical cancer and 288 matched controls with original serum samples were identified from the Khon Kaen Cohort, established in the North-East of Thailand, by linkage to the Khon Kaen population based cancer registry. C. trachomatis specific IgG antibodies at recruitment were measured by microimmunofluorescence and assessed for association with cervical cancer using STATA release10. No significant link was noted either with all cancers or after removal of adenocarcinomas. The results suggest no association between Chlamydia infection and cervical cancer development in North-East Thailand, but possible influencing factors must be considered in any future research on this topic.

• 근관절건강학회지
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• 제28권2호
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• pp.174-182
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• 2021

Purpose: This study is a secondary data analysis study to identify factors related to the quality of life of people aged 65 y or older, according household type. Methods: In 2019, the study extracted the data from the elderly participants (65 y of age or older) from G province Community Health Survey. The data were compiled and analyzed in a composite sample. Results: The quality of life was lowest among single people, grandparents-grandchildren (F=39.88, p<.001). Variables that significantly influenced quality of life in single-person households were basic security(β=-.03, p=.002), high-risk drinking (β=.04, p=.002), number of day to walk (β=.01, p<.001), diabetes mellitus (β=-.03, p<.001), depression (β=-.02, p<.001), and contact frequency (β=.00, p<.001). Variables that significantly influenced grandparents-grandchildren households were basic security (β=.03, p<.001), smoking(β=-.02, p<.001), number of day to walk (β=.00, p<.001), hypertension (β=-.01, p=.009), diabetes mellitus (β=-.04, p<.001), cognitive impairment (β=-.02, p<.001), depression(β=-.02, p<.001), contact frequency (β=.01, p<.001), and neighborhood trust (β=.02, p<.001). Conclusion: In this study, there were differences in health-related quality of life for each type of household, and various support systems are needed in their social networks to suit their characteristics.

• 한국연초학회지
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• 제29권2호
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• pp.90-97
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• 2007

This study was conducted to evaluate the effect of additives (antioxidants for free radicals reduction) in cigarette filter treated with various antioxidants (three types of proanthocyanidins and ascorbic acid) and various concentrations of ascorbic acid and loaded with activated carbon on the delivery of free radicals of mainstream smoke (MS) by ESR. Also, we analyzed Hoffmann's analytes andscavenger activity according to the storage time and in vitro cytotoxicity. The analysis of spin number of vapor and particulate phase free radicals in MS are decreased to $14{\sim}24\;%$ and $16{\sim}40\;%$, respectively. As aresult of antioxidant potential for inactivity of vapor and particulate phase free radicals, natural antioxidants were more effective than ascorbic acid. Based on the result of the analysis of Hoffmann's analytes for various antioxidantstreated cigarette filters during the smoking, cigarette filter treated with ascorbic acid showed the lower amount of the deliveries of hydroquinone, isoprene and quinoline in MS than those treated with the other antioxidants. In the significant t-test on the difference of the cytotoxicity among the various antioxidants treated-cigarette filters, there are no significant differences at the 95 % confidence level. Those results indicated that the antioxidants were useful for reducing free radicals in MS because of the fast reaction between antioxidant and free radicals.

• 한국의상디자인학회지
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• 제21권1호
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• pp.1-15
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• 2019

The purpose of this study is to develop ICT utilization learning materials for a chapter titled 'Environment Friendly Clothing and Reform of Clothing' in technology and home economics textbooks for Year 2 students in middle school. The research methods were selected from ten types of junior high school technology textbooks, which were revised in 2009, and mainly focused on items such as jeans, shirts, shirts, cardigans, and skirts, Using selected textiles and basic design t-shirts, five works were made using structural and decorative details. The results of this study are as follows. First, textile products shown in the chapter 'Environment Friendly Clothing and Reform of Clothing' are most commonly worn and found in daily life. With regard to a reuse method, structural changes to clothing are proposed. For example, cases relating to the changing of a neckline or the use of a shirt or a sleeve are presented. There are some decoration methods adapted in reuse; using ornaments, such as spangles and emblems, patchwork, shirring and the constucting of collages. Second, following the plan, 5 items are designed with T-shirts, shirts, cardigans and skirts. For the T-shirt design, other fabrics including organza and neoplan are used from design point of view, in addition to reused textile products. Detailed structural changes of necklines, sleeves and collars and detailed and the ornamentation method including shirring, smoking, patchwork and collages are used. Third, this study proposes 6 categories (profile, design planning, diagram, reused textile product, production method and order and pictures of T-shirts developed) under the title of 'T-shirt Made Out of Disposed Clothing', selecting a blog as active teaching and learning material as a part of the ICT utilization in educational settings.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3705-3709
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• 2013

Background: To investigate epidermal growth factor receptor (EGFR) gene mutations in patients with non-small cell lung cancer (NSCLC) and to analyze any relationship with clinicopathological features and prognosis. Materials and Methods: EGFR gene exons 18-21 in 48 specimens of paraffin-embedded tumor tissue from NSCLC patients were amplified by PCR, followed by direct sequencing and analysis of links to clinicopathological features and prognosis. Results: EGFR mutations were detected in 18 of 48 (42.6%) patients with NSCLC. There were 9 cases of mutations in exon 20, 7 in exon 19 and 2 in exon 21. Mutations were more frequently observed in women (5/7 pts, 71.4%) than in men (13/41 pts, 31.7%) (p=0.086) and in non-smokers (5/5 pts, 100%) than smokers (13/43 pts, 30.2%). There was negative correlation of EGFR mutations with smoking status (p=0.005). EGFR mutations were more frequently observed with adenocarcinoma histology (13/32 pts, 40.6%) than in other types (5/16 pts, 31.3%) (p=0.527). The patients with EGFR mutations had better survival than those with wild-type EGFR (p=0.08). There was no association of EGFR mutations with metastatic spread. Conclusions: EGFR mutations in NSCLC were here demonstrated more frequently in females, non-smokers and adenocarcinoma histology in the western region of Turkey. Patients with EGFR mutations have a better prognosis.

• 한국치위생학회지
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• 제15권1호
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• pp.91-99
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• 2015

Objectives: The purpose of the study was to investigate the relationship between internet addiction and health in dental hygiene students. Methods: A self-reported questionnaire was completed by 216 dental hygiene students in Daegu from June 9 to 13, 2014. Data were analyzed by descriptive statistics, t-test, and ANOVA using SAS 9.2 program. The instruments included Korean internet addiction scale(K scale) and Korean version of the general health questionnaire. General characteristics consisted of grade, religion, residential types, economic condition, place of internet use, duration, purpose, and time of use. Physical characteristics consisted of subjective physical condition, smoking, alcohol drinking, exercise above twice per week, musculoskeletal disease, and location of physical symptoms. Psychiatric scale and 6 questions of physical characteristics were consulted by the statistician of preventive medicine department. Results: Internet users over 4 hours manifested the poor mental health, while those who uses internet under 2 hours showed good mental health(F = 1.41, p < 0.01). The students having good physical condition showed better mental health than those with poor physical condition(t = -2.81, p < 0.01). The students exercising at least twice a week showed better mental health than those who do not exercise(t = -3.10, p < 0.01). Those who having musculoskeletal symptoms showed higher index of internet addiction score than those who do not(t = 4.21, p < 0.01). Those who have no musculoskeletal symptoms tended to have better mental health than those who have musculoskeletal symptoms(t = 2.28, p < 0.05). The variables correlated to mental health were internet addiction, subjective physical condition, and exercise at least twice a week. The severity level of internet addiction leads to poor mental health(r = 0.26, p < 0.001). Conclusions: Internet addiction is closely related to mental health. So the students must know the danger of internet addiction. Proper health education is necessary for the prevention of addiction symptoms.