• Title/Summary/Keyword: Type I error

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Basic Research for Resistance Prediction of Aluminium Alloy Plate Girders Subjected to Patch Loading (패치로딩을 받는 알루미늄 합금 플레이트 거더의 강도 예측에 대한 기초 연구)

  • Oh, Young-Cheol;Bae, Dong-Gyun;Ko, Jae-Yong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.20 no.2
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    • pp.218-227
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    • 2014
  • In this paper, it performed to the elastic-plastic large deflection series analysis using the experimental model and predicted a failure mode and ultimate strength. The collapse mode of numerical analysis model is formed a plastic hinge on loaded flange and consistent with the collapse mode of experimental model. Also, The yield line is formed in the web could observed that have occurred the crippling collapse mode and the ultimate loads of the experimental model and numerical analysis model have maintained linearly Means 1.07, Standard deviation 0.04, Coefficient of variation(COV) 0.04 and the result of ultimate loads have appeared approximately 8% error rate. it was found that very satisfied to the experimental results and the applied rules. if it is considered to be maintain a reasonable safety level, it is possible to predict the failure modes of aluminium alloy plate girders and ultimate loads.

The Study for Improvement of Data-Quality of Cut-Slope Management System Using Machine Learning (기계학습을 활용한 도로비탈면관리시스템 데이터 품질강화에 관한 연구)

  • Lee, Se-Hyeok;Kim, Seung-Hyun;Woo, Yonghoon;Moon, Jae-Pil;Yang, Inchul
    • The Journal of Engineering Geology
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    • v.31 no.1
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    • pp.31-42
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    • 2021
  • Database of Cut-slope management system (CSMS) has been constructed based on investigations of all slopes on the roads of the whole country. The investigation data is documented by human, so it is inevitable to avoid human-error such as missing-data and incorrect entering data into computer. The goal of this paper is constructing a prediction model based on several machine-learning algorithms to solve those imperfection problems of the CSMS data. First of all, the character-type data in CSMS data must be transformed to numeric data. After then, two algorithms, i.g., multinomial logistic regression and deep-neural-network (DNN), are performed, and those prediction models from two algorithms are compared. Finally, it is identified that the accuracy of DNN-model is better than logistic model, and the DNN-model will be utilized to improve data-quality.

Statistical methods for testing tumor heterogeneity (종양 이질성을 검정을 위한 통계적 방법론 연구)

  • Lee, Dong Neuck;Lim, Changwon
    • The Korean Journal of Applied Statistics
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    • v.32 no.3
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    • pp.331-348
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    • 2019
  • Understanding the tumor heterogeneity due to differences in the growth pattern of metastatic tumors and rate of change is important for understanding the sensitivity of tumor cells to drugs and finding appropriate therapies. It is often possible to test for differences in population means using t-test or ANOVA when the group of N samples is distinct. However, these statistical methods can not be used unless the groups are distinguished as the data covered in this paper. Statistical methods have been studied to test heterogeneity between samples. The minimum combination t-test method is one of them. In this paper, we propose a maximum combinatorial t-test method that takes into account combinations that bisect data at different ratios. Also we propose a method based on the idea that examining the heterogeneity of a sample is equivalent to testing whether the number of optimal clusters is one in the cluster analysis. We verified that the proposed methods, maximum combination t-test method and gap statistic, have better type-I error and power than the previously proposed method based on simulation study and obtained the results through real data analysis.

An efficient robust cost optimization procedure for rice husk ash concrete mix

  • Moulick, Kalyan K.;Bhattacharjya, Soumya;Ghosh, Saibal K.;Shiuly, Amit
    • Computers and Concrete
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    • v.23 no.6
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    • pp.433-444
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    • 2019
  • As rice husk ash (RHA) is not produced in controlled manufacturing process like cement, its properties vary significantly even within the same lot. In fact, properties of Rice Husk Ash Based Concrete (RHABC) are largely dictated by uncertainty leading to huge deviations from their expected values. This paper proposes a Robust Cost Optimization (RCO) procedure for RHABC, which minimizes such unwanted deviation due to uncertainty and provides guarantee of achieving desired strength and workability with least possible cost. The RCO simultaneously minimizes cost of RHABC production and its deviation considering feasibility of attaining desired strength and workability in presence of uncertainty. RHA related properties have been modeled as uncertain-but-bounded type as associated probability density function is not available. Metamodeling technique is adopted in this work for generating explicit expressions of constraint functions required for formulation of RCO. In doing so, the Moving Least Squares Method is explored in place of conventional Least Square Method (LSM) to ensure accuracy of the RCO. The efficiency by the proposed MLSM based RCO is validated by experimental studies. The error by the LSM and accuracy by the MLSM predictions are clearly envisaged from the test results. The experimental results show good agreement with the proposed MLSM based RCO predicted mix properties. The present RCO procedure yields RHABC mixes which is almost insensitive to uncertainty (i.e., robust solution) with nominal deviation from experimental mean values. At the same time, desired reliability of satisfying the constraints is achieved with marginal increment in cost.

Novel nomogram-based integrated gonadotropin therapy individualization in in vitro fertilization/intracytoplasmic sperm injection: A modeling approach

  • Ebid, Abdel Hameed IM;Motaleb, Sara M Abdel;Mostafa, Mahmoud I;Soliman, Mahmoud MA
    • Clinical and Experimental Reproductive Medicine
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    • v.48 no.2
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    • pp.163-173
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    • 2021
  • Objective: This study aimed to characterize a validated model for predicting oocyte retrieval in controlled ovarian stimulation (COS) and to construct model-based nomograms for assistance in clinical decision-making regarding the gonadotropin protocol and dose. Methods: This observational, retrospective, cohort study included 636 women with primary unexplained infertility and a normal menstrual cycle who were attempting assisted reproductive therapy for the first time. The enrolled women were split into an index group (n=497) for model building and a validation group (n=139). The primary outcome was absolute oocyte count. The dose-response relationship was tested using modified Poisson, negative binomial, hybrid Poisson-Emax, and linear models. The validation group was similarly analyzed, and its results were compared to that of the index group. Results: The Poisson model with the log-link function demonstrated superior predictive performance and precision (Akaike information criterion, 2,704; λ=8.27; relative standard error (λ)=2.02%). The covariate analysis included women's age (p<0.001), antral follicle count (p<0.001), basal follicle-stimulating hormone level (p<0.001), gonadotropin dose (p=0.042), and protocol type (p=0.002 and p<0.001 for short and antagonist protocols, respectively). The estimates from 500 bootstrap samples were close to those of the original model. The validation group showed model assessment metrics comparable to the index model. Based on the fitted model, a static nomogram was built to improve visualization. In addition, a dynamic electronic tool was created for convenience of use. Conclusion: Based on our validated model, nomograms were constructed to help clinicians individualize the stimulation protocol and gonadotropin doses in COS cycles.

Usefulness of Brain Phantom Made by Fused Filament Fabrication Type 3D Printer (적층 제조형 방식의 3D 프린터로 제작한 뇌 팬텀의 유용성)

  • Lee, Yong-Ki;Ahn, Sung-Min
    • Journal of radiological science and technology
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    • v.43 no.6
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    • pp.453-460
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    • 2020
  • The price of the Brain phantom (Hoffman 3D brain phantom) used in nuclear medicine is quite expensive, it is difficult to be purchased by a medical institution or an educational institution. Therefore, the purpose of present research is to produce a low-price 3D brain phantom and evaluate its usefulness by using a 3D printer capable of producing 3D structures. The New 3D brain phantom consisted of 36 slices 0.7 mm thick and 58 slices 1.5 mm thick. A 0.7 mm thick slice was placed between 1. 5 mm thick slices to produce a composite slice. ROI was set at the gray matter and white matter scanned with CT to measure and compare the HU, in order to verify the similarity between PLA which was used as the material for the New 3D brain phantom and acrylic which was used as the material for Hoffman 3D brain phantom. As a result of measuring the volume of each Phantom, the error rate was 3.2% and there was no difference in the signal intensity in five areas. However, there was a significant difference in the average values of HU which was measured at the gray and white matter to verify the similarity between PLA and acrylic. By reproducing the previous Hoffman 3D brain phantom with a 100 times less cost, I hope this research could contribute to be used as the fundamental data in the areas of 3D printer, nuclear medicine and molecular imaging and to increasing the distribution rate of 3D brain phantom.

The Relationship between Oral Health-Related Factors and Grip Strength in the Elderly

  • Kim, Ki-Eun
    • Journal of dental hygiene science
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    • v.22 no.1
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    • pp.37-43
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    • 2022
  • Background: Among the health problems in old age, oral health is closely related to nutrition intake and digestion, so although it is an important factor in the well-being of the elderly along with general health, studies examining the relationship between oral health-related factors and grip strength of the elderly are insufficient. Therefore, this study intends to examine the relationship between oral health-related factors and grip strength, which are closely related to the general health of the elderly. Methods: This study used data from the 7th period of Korea National Health and Nutrition Survey (2016~2018) approved by the Research Ethics Review Committee of the Korea Centers for Disease Control and Prevention. Complex sample frequency analysis and descriptive statistics were performed, and general linear model analysis was performed to confirm the relationship between demographic characteristics, oral health -related factors and grip strength. The statistical analysis was performed using IBM SPSS Statistics for Windows, Version 23.0, and the significance test was based on type I error level of 0.05. Results: Grip strength was higher in the case of no discomfort than in the case of discomfort in relation to mastication discomfort and grip strength (B=0.927, p<0.001). In addition, the grip strength was decreased by 1.348 times when not using dental floss (p<0.001) and when not using mouth wash was 1.480 times (p<0.001). Conclusion: In this study, in the relationship between oral health-related factors and grip strength, grip strength was found to be high in the absence of mastication discomfort. and in the case of using dental floss and mouthwash the elderly showed high grip strength. Therefore, it is suggested to present a lifestyle to improve hand function and grip strength in the elderly and develop a program to increase grip strength and provide them at the same time during oral health education.

A Revision of the Phylogeny of Helicotylenchus Steiner, 1945 (Tylenchida: Hoplolaimidae) as Inferred from Ribosomal and Mitochondrial DNA

  • Abraham Okki, Mwamula;Oh-Gyeong Kwon;Chanki Kwon;Yi Seul Kim;Young Ho Kim;Dong Woon Lee
    • The Plant Pathology Journal
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    • v.40 no.2
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    • pp.171-191
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    • 2024
  • Identification of Helicotylenchus species is very challenging due to phenotypic plasticity and existence of cryptic species complexes. Recently, the use of rDNA barcodes has proven to be useful for identification of Helicotylenchus. Molecular markers are a quick diagnostic tool and are crucial for discriminating related species and resolving cryptic species complexes within this speciose genus. However, DNA barcoding is not an error-free approach. The public databases appear to be marred by incorrect sequences, arising from sequencing errors, mislabeling, and misidentifications. Herein, we provide a comprehensive analysis of the newly obtained, and published DNA sequences of Helicotylenchus, revealing the potential faults in the available DNA barcodes. A total of 97 sequences (25 nearly full-length 18S-rRNA, 12 partial 28S-rRNA, 16 partial internal transcribed spacer [ITS]-rRNA, and 44 partial cytochrome c oxidase subunit I [COI] gene sequences) were newly obtained in the present study. Phylogenetic relationships between species are given as inferred from the analyses of 103 sequences of 18S-rRNA, 469 sequences of 28S-rRNA, 183 sequences of ITS-rRNA, and 63 sequences of COI. Remarks on suggested corrections of published accessions in GenBank database are given. Additionally, COI gene sequences of H. dihystera, H. asiaticus and the contentious H. microlobus are provided herein for the first time. Similar to rDNA gene analyses, the COI sequences support the genetic distinctness and validity of H. microlobus. DNA barcodes from type material are needed for resolving the taxonomic status of the unresolved taxonomic groups within the genus.

Optimum Design of Two Hinged Steel Arches with I Sectional Type (SUMT법(法)에 의(依)한 2골절(滑節) I형(形) 강재(鋼材) 아치의 최적설계(最適設計))

  • Jung, Young Chae
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.12 no.3
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    • pp.65-79
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    • 1992
  • This study is concerned with the optimal design of two hinged steel arches with I cross sectional type and aimed at the exact analysis of the arches and the safe and economic design of structure. The analyzing method of arches which introduces the finite difference method considering the displacements of structure in analyzing process is used to eliminate the error of analysis and to determine the sectional force of structure. The optimizing problems of arches formulate with the objective functions and the constraints which take the sectional dimensions(B, D, $t_f$, $t_w$) as the design variables. The object functions are formulated as the total weight of arch and the constraints are derived by using the criteria with respect to the working stress, the minimum dimension of flange and web based on the part of steel bridge in the Korea standard code of road bridge and including the economic depth constraint of the I sectional type, the upper limit dimension of the depth of web and the lower limit dimension of the breadth of flange. The SUMT method using the modified Newton Raphson direction method is introduced to solve the formulated nonlinear programming problems which developed in this study and tested out throught the numerical examples. The developed optimal design programming of arch is tested out and examined throught the numerical examples for the various arches. And their results are compared and analyzed to examine the possibility of optimization, the applicablity, the convergency of this algorithm and with the results of numerical examples using the reference(30). The correlative equations between the optimal sectional areas and inertia moments are introduced from the various numerical optimal design results in this study.

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Sensitivity Experiment of Surface Reflectance to Error-inducing Variables Based on the GEMS Satellite Observations (GEMS 위성관측에 기반한 지면반사도 산출 시에 오차 유발 변수에 대한 민감도 실험)

  • Shin, Hee-Woo;Yoo, Jung-Moon
    • Journal of the Korean earth science society
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    • v.39 no.1
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    • pp.53-66
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    • 2018
  • The information of surface reflectance ($R_{sfc}$) is important for the heat balance and the environmental/climate monitoring. The $R_{sfc}$ sensitivity to error-induced variables for the Geostationary Environment Monitoring Spectrometer (GEMS) retrieval from geostationary-orbit satellite observations at 300-500 nm was investigated, utilizing polar-orbit satellite data of the MODerate resolution Imaging Spectroradiometer (MODIS) and Ozone Mapping Instrument (OMI), and the radiative transfer model (RTM) experiment. The variables in this study can be cloud, Rayleigh-scattering, aerosol, ozone and surface type. The cloud detection in high-resolution MODIS pixels ($1km{\times}1km$) was compared with that in GEMS-scale pixels ($8km{\times}7km$). The GEMS detection was consistent (~79%) with the MODIS result. However, the detection probability in partially-cloudy (${\leq}40%$) GEMS pixels decreased due to other effects (i.e., aerosol and surface type). The Rayleigh-scattering effect in RGB images was noticeable over ocean, based on the RTM calculation. The reflectance at top of atmosphere ($R_{toa}$) increased with aerosol amounts in case of $R_{sfc}$<0.2, but decreased in $R_{sfc}{\geq}0.2$. The $R_{sfc}$ errors due to the aerosol increased with wavelength in the UV, but were constant or slightly decreased in the visible. The ozone absorption was most sensitive at 328 nm in the UV region (328-354 nm). The $R_{sfc}$ error was +0.1 because of negative total ozone anomaly (-100 DU) under the condition of $R_{sfc}=0.15$. This study can be useful to estimate $R_{sfc}$ uncertainties in the GEMS retrieval.