• Proceedings of the KOR-BRONCHOESO Conference
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• 1979.05a
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• pp.3.1-3
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• 1979

The aim of ear operation is to cease otorrhea and to restore hearing. The ceasation of otorrhea and the graft of tympanic membrane are reached to successful stage, and yet hearing restoration process still remains further to need a matter of development. Authors carried out 67 cases hearing restoration operation among 154 patients who had been undertaken mastoid-tympanoplasty during period of Feb. 1978 through March 1979. 54 cases have been followed for this study among 67 cases hearing restoration operation. The used material of operation are almostly incus and some cases with TORP. This paper is dealing with its surgical method and postoperative audimetric study.

• The Journal of the Acoustical Society of Korea
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• v.31 no.5
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• pp.273-279
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• 2012

In this thesis, a nonlinear compression fitting method was studied for each frequency channel of a 64 channel digital hearing aid. Unlike conventional fitting formula method done from the result of the hearing loss test, the present fitting method uses the auditory threshold of sound pressure measured near the tympanic membrane while ITE (In-The-Ear) hearing aid is fitted into the user's ear canal. Also, the spectral distribution of the voice sound pressure was used for realizing of output sound pressure compression curves against input sound pressure level. Theoretical research results of FFT-iFFT compression algorithm has been evaluated by experimental gain measurements at each different input sound pressure level 50 dB, 70 dB, 90 dB respectively.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1981.05a
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• pp.41.1-41
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• 1981

The combination of congenital stapes fixation and proximal symphalangism has been described in several kindreds. It exhibits autosomal dominant inheritance. A patient, 11-year-old female, visited department of otolaryngology of SNUH in December, 1980. Her complaint was bilateral hearing loss since birth. Physical examination revealed fusion of proximal interphalangeal joints of both 4th and 5th fingers. Tympanic membrane was normal. Temporal bone X-ray was normal. Pure tone audiogram revealed about 60 dB conductive loss with horizontal curve. On exploratory tympanotomy of right side, bony fixation of stapedial footplate was found. So, stapedectomy with connective tissue wire prosthesis was performed. As a result, marked improvement of hearing was obtained with 5 dB A-B gap on operated side.

• Journal of Korea Multimedia Society
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• v.22 no.8
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• pp.923-929
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• 2019

In this paper, biomimetic based physical ear model proposed for measuring the characteristics of a hybrid-acoustic sensor for fully implantable middle-ear hearing aid. The proposed physical ear model consists of the external ear, middle-ear, and cochlea. The physical ear model was implemented based on the anatomical structure and CT images of the human ear. To confirm the characteristics of the ear model, the vibrational characteristics of the stapes was measured after applying sound pressure to the tympanic membrane. The measured results were compared with the vibrational characteristics of the human temporal bone specified by ASTM F2504-05. Through the comparison results, the feasibility of the proposed ear model was confirmed. Then, after attaching the hybrid-acoustic sensor to the ear model, the output characteristics of the ECM and acceleration sensor were measured according to the sound pressure. The measured results were compared with previous studies using human temporal bone, and the usefulness of the proposed physical ear model was verified through the analysis results.

• Journal of Life Science
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• v.25 no.5
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• pp.523-532
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• 2015

A variety of previous pharmacological studies have suggested Liriope platyphylla (L. platyphylla) may exert beneficial biological effects on inflammation, diabetes, neurodegenerative disorder, obesity, constipation, and atopic dermatitis. In addition, hydrocolloid membranes (HCMs) have attracted attention in dermatological care, including in the treatment of scleroderma skin ulcers, cutaneous ulcers, permanent tympanic membrane perforations, pressure sores, and decubitus ulcers in the elderly. To investigate the therapeutic effects of HCM containing an aqueous extract of L. platyphylla (HCM-LP) on second-degree burn wounds, their physico-chemical properties were analyzed and the therapeutic effects were observed in SD rats after treatment with HCM-LP for 14 days. Significant declines in tensile strength (38.4%) and absorptiveness (46.3%), as well as an increase in surface roughness (38.1%) were detected in HCM-LP compared with that of HCM. In SD rats with burned skin, the wound diameter was shorter in the HCM-LP treated group than in the GZ group on post-surgical day 14, while the significant improvements in scar tissue reduction, epithelium regeneration, angiogenesis, and extracellular matrix deposition were observed in the HCM-LP-treated group during all experimental periods. Overall, these results suggest HCM-LP may accelerate the process of healing the burn injury skin of SD rats through the regulation of angiogenesis and connective tissue formation.

• Journal of Korean Biological Nursing Science
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• v.14 no.1
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• pp.25-32
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• 2012

Purpose: influence of benzodiazepine (midazolam)or cholinergic inhibitor (atropine or glycopyrrlate) on intra-operative body temperature remains unclear and controversial. This study compares intra-operative body temperature in 50 abdominal surgical patients under general anesthesia between the administration of midazolam and glycopyrrolate in combination, or glycopyrrolate alone. Methods: Patients who underwent abdominal surgery were recruited from September 2008 through October 2009 at Gachon University Gil hospital in incheon. Core body temperature was measured in the right ear using a tympanic membrane thermometer at induction of general anesthesia and at 1 hr, 2 hr, and 3 hr after induction. Results: There were no differences in core body temperature at any measurement point between either patient group (F=1.08, $p$=.377). Core body temperature decreased throughout the 3 hr after induction in both groups (F=9.22, $p$ <.001). Specially, core temperatures at induction of general anesthesia (p<.001), 1 hr (p<.001), 2 hr ($p$ <.001), and 3 hr ($p$ <.001) after induction were lower than before administration of midazolam and glycopyrrolate, or glycopyrrolate alone. Conclusion: We conclude that a cholinergic inhibitor (glycopyrrolate, 0.1 mg) therefore seems not to affect intra-operative body temperature of patients given a benzodiazepine (midazolam, 0.04 mg $kg^{-1}$), and not to increase body temperature in patients not given a benzodiazepine during the 3 hr after the induction of general anesthesia. Intra-operative warming therefore is needed to prevent hypothermia in surgical patients who receive pre-operative administration of midazolam and/or glycopyrrolate.

• Journal of Biomedical Engineering Research
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• v.39 no.5
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• pp.183-187
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• 2018

In this paper, we investigated the efficiency according to the output transmission method of the round window driving type AMEIs (active middle ear implants) through the cadaveric experiment. For the experiment, we fabricated DRT (direct rod transducer) and FMT (floating mass transducer) type vibrational transducers based on our previous studies and conducted their output characteristics were measured. TCBT (tri-coil bellows transducer) and DFMT (differential floating mass transducer) were implemented with the same driving force and electrical characteristics as one of DRT and FMT, respectively. In the experiment using three human temporal bone, normal stapes vibration was measured with 1 Pa in front of tympanic membrane, and then was compared with each output of transducers. From the comparison, the DRT type vibration transducer was superior in overall energy transfer efficiency, especially in the low frequency range. There was no difference in implantation difficulty between the two transducers. The results of this study suggest that the DRT type vibrational transducer is more efficient and needs further study to overcome the low frequency degradation in round window approaching with FMT.

• Journal of the Optical Society of Korea
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• v.20 no.2
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• pp.269-275
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• 2016

This study has investigated the feasibility of 980-nm low-energy pulsed near-infrared laser stimulation to evoke auditory responses, as well as the effects of radiant exposure and pulse duration on auditory responses. In the experiments, a hole was drilled in the basal turn of the cochlea in guinea pigs. An optical fiber with a 980-nm pulsed infrared laser was inserted into the hole, orientating the spiral ganglion cells in the cochlea. To model deafness, the tympanic membrane was mechanically damaged. Acoustically evoked compound action potentials (ACAPs) were recorded before and after deafness, and optically evoked compound action potentials (OCAPs) were recorded after deafness. Similar spatial selectivity between optical and acoustical stimulation was found. In addition, OCAP amplitudes increased with radiant exposure, indicating a photothermal mechanism induced by optical stimulation. Furthermore, at a fixed radiant exposure, OCAP amplitudes decreased as pulse duration increased, suggesting that optical stimulation might be governed by the time duration over which the energy is delivered. Thus, the current experiments have demonstrated that a 980-nm pulsed near-infrared laser with low energy can evoke auditory neural responses similar to those evoked by acoustical stimulation. This approach could be used to develop optical cochlear implants.

• Pediatric Infection and Vaccine
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• v.9 no.1
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• pp.110-116
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• 2002

Tuberculous otitis media is a very rare disease in extrapulmonary tuberculosis and in chronic otitis media nowadays. The characteristic signs seem to have altered from the past ones. And the suspicion index is very low that there is often a considerable delay prior to diagnosis. This might result in irreversible complications such as hearing loss, facial nerve paralysis and labyrinthitis. It is difficult to be defined by culture, so many patients with tuberculous otitis media are subjected to have surgery without a correct etiologic diagnosis. Therefore bacteriologic study of secretion and pathologic examinations of biopsied tissue are mandatory. We report one year and 11 months old boy with tuberculous otitis media having painful otorrhea and perforated tympanic membrane diagnosed by histologic finding and polymerase chain reaction(PCR). And we would like to emphasize the fact that tuberculous otitis media must be considered in the differential diagnosis of persistent suppurative otitis media despite appropriate antibiotic therapy considering the increasing tendency in incidence of Tuberculosis in Korea these days.

• Journal of Clinical Otolaryngology Head and Neck Surgery
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• v.29 no.2
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• pp.235-239
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• 2018

Due to the structure with one end closed, the external ear resonance effect in which the high frequency is amplified can be generated, and the sound can be perceived well. The external ear resonance normally has a first peak and a second peak. On average, the first peak has a gain of 18.6 dB at 2620 Hz and the second peak has a gain of 18.2 dB at 4210 Hz. The resonance of the external auditory canal changes with the state of the tympanic membrane, the presence of the ventilation tube, and the structure (length, diameter, shape) of the external auditory canal. A patient with a postauricular meatomastoid cutaneous fistula was admitted to the hospital with a foreign body which is the molding of the hearing aid. After removal of the foreign body, the resonance of the external auditory canal was lost and the subjective sound cognitive ability decreased. In the case of postauricular meatomastoid cutaneous fistula, we confirmed the improvement of sound cognitive ability, the change of pure tone hearing threshold, and the change of the external ear resonance after reconstruction of the ear canal without middle ear reconstruction.