• 제목/요약/키워드: Two-stage optimization

검색결과 264건 처리시간 0.021초

Optimization of Fed-Batch Fermentation for Production of Poly-$\beta$-Hydroxybutyrate in Alcaligenes eutrophus

  • Lee, In-Young;Choi, Eun-Soo;Kim, Guk-Jin;Nam, Soo-Wan;Shin, Yong-Cheol;Chang, Ho-Nam;Park, Young-Hoon
    • Journal of Microbiology and Biotechnology
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    • 제4권2호
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    • pp.146-150
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    • 1994
  • Production of poly-$\beta$-hydroxybutyrate (PHB) in fed-batch fermentation was studied. Utilization of carbon for PHB biosynthesis was investigated by using feeding solutions with different ratios of carbon to nitrogen (C/N). It was observed that at a high C/N ratio carbon source was more preferably utilized for PHB accumulation while its consumption for cellular metabolism appeared to be more favored at a low C/N value. A high cell concentration (184 g/l) was achieved when ammonium hydroxide solution was fed to control the pH, which was also utilized as the sole nitrogen source. For the mass production of PHB, two-stage fed-batch operations were carried out where PHB accumulation was observed to be stimulated by switching the ammonium feeding mode to the nitrogen limiting condition. A large amount of PHB (108 g/l) was obtained with cellular content of 80% within 50 hrs of operation.

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민감도가 고려된 알고리듬을 이용한 최적화 방법에 관한 연구 (A Study on the Optimization Method using the Genetic Algorithm with Sensitivity Analysis)

  • 이재관;신효철
    • 대한기계학회논문집A
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    • 제24권6호
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    • pp.1529-1539
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    • 2000
  • A newly developed optimization method which uses the genetic algorithm combined with the sensitivity analysis is presented in this paper. The genetic algorithm is a probabilistic method, searching the optimum at several points simultaneously, requiring only the values of the object and constraint functions. It has therefore more chances to find global solution and can be applied various problems. Nevertheless, it has such shortcomings that even it approaches the optimum rapidly in the early stage, it slows down afterward and it can't consider the constraints explicitly. It is only because it can't search the local area near the current points. The traditional method, on the other hand, using sensitivity analysis is of great advantage in searching the near optimum. Thus the combination of the two techniques makes use of the individual advantages, that is, the superiority both in global searching by the genetic algorithm and in local searching by the sensitivity analysis. Application of the method to the several test functions verifies that the method suggested is very efficient and powerful to find the global solutions, and that the constraints can be considered properly.

Structural damage detection based on residual force vector and imperialist competitive algorithm

  • Ding, Z.H.;Yao, R.Z.;Huang, J.L.;Huang, M.;Lu, Z.R.
    • Structural Engineering and Mechanics
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    • 제62권6호
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    • pp.709-717
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    • 2017
  • This paper develops a two-stage method for structural damage identification by using modal data. First, the Residual Force Vector (RFV) is introduced to detect any potentially damaged elements of structures. Second, data of the frequency domain are used to build up the objective function, and then the Imperialist Competitive Algorithm (ICA) is utilized to estimate damaged extents. ICA is a heuristic algorithm with simple structure, which is easy to be implemented and it is effective to deal with high-dimension nonlinear optimization problem. The advantages of this present method are: (1) Calculation complexity can be decreased greatly after eliminating many intact elements in the first step. (2) Robustness, ICA ensures the robustness of the proposed method. Various damaged cases and different structures are investigated in numerical simulations. From these results, anyone can point out that the present algorithm is effective and robust for structural damage identification and is also better than many other heuristic algorithms.

원심 펌프의 최적 설계 (Design Optimization of Centrifugal Pumps)

  • 오형우;정명균;김상철;양근영;하진수
    • 대한기계학회논문집B
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    • 제23권2호
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    • pp.254-261
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    • 1999
  • An optimal design code for centrifugal pumps has been developed to determine geometric and fluid dynamic variables under appropriate design constraints. The optimization problem has been formulated with a nonlinear objective function to minimize one, two or all of the fluid dynamic losses, the net positive suction head required and the product price of a pump stage depending on the weighting factors selected as the design compromise. The optimal solution Is obtained by means of the Hooke and Jeeves direct search method. The performance analysis Is based on the mean streamline analysis using the present state-of-the-art loss correlations. The optimized efficiency and design variables of centrifugal pumps are presented in this paper as a function of non-dimensional specific speed in the range, $0.5{\leq}N$, ${\leq}1.3$. The diagrams presented herein can be used efficiently in the preliminary design phase of centrifugal pumps.

Economic Analysis of Snow Damage on Sugi (Cryptomeria japonica) Forest Stands in Japan Within the Forest Stand Optimization Framework

  • Yoshimoto, Atsushi;Kato, Akio;Yanagihara, Hirokazu
    • Journal of Forest and Environmental Science
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    • 제24권3호
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    • pp.143-149
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    • 2008
  • We conduct economic analysis of the snow damage on sugi (Cryptomeria japonica) forest stands in Toyama Prefecture, Japan. We utilize a single tree and distant independent growth simulator called "Silv-Forest." With this growth simulator, we developed an optimization model by dynamic programming, called DP-Silv (Dynamic Programming Silv-Forest). The MS-PATH (multiple stage projection alternative technique) algorithm was embedded as a searching algorithm of dynamic programming. The height / DBH ratio was used to constrain the thinning regime for snow damage protection. The optimal rotation age turned out to be 65 years for the non-restricted case, while it was 50 years for the restricted case. The difference in NPV of these two cases as the induced costs ranged from 179,867 to 1,910,713yen/ha over the rotation age of 20 to 75 years. Under the optimal rotation of 65 years, the cost became 914,226 yen/ha. The estimated annual payment based on the difference in NPV, was from 9,869 yen/ha/yr to 85,900 yen/ha/yr. All in all, 10,000 yen/ha/yr to 20,000 yen/ha/yr seems to cover the payment from the rotation age of 35 to 75 years.

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유전자 재조합 대장균 발효의 최대 생산성을 위한 생육에서 제품 생성으로 전환시기의 최적화 (Optimization of Switching Time from Growth to Product Formation for Maximum Productivity of Recombinant Escherichia coli Fermentation)

  • ;신평균;서진호
    • 한국미생물·생명공학회지
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    • 제18권4호
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    • pp.394-400
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    • 1990
  • 유전자 조작된 세포 발효공정의 생산수율을 최대화하기 위하여 세포의 성장속도와 제품 생성속도간의 상반관계를 고려하여야 한다. 유전자 조작된 E.coli 발효에 있어, 최적화 이론을 적용하여 두 속도의 가중치를 결정함으로써 생산수율의 최대화를 꾀하였다. 성장저해제의 농도는 비 성장속도를 조절하고 결국 융합된 유전자의 발현 속도를 조절하는 변수로 사용되다. 이런 system의 특성을 위하여 간단한 unstructured model를 사용하였다.

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Relaying Protocols and Delay Analysis for Buffer-aided Wireless Powered Cooperative Communication Networks

  • Zhan, Jun;Tang, Xiaohu;Chen, Qingchun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제12권8호
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    • pp.3542-3566
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    • 2018
  • In this paper, we investigate a buffer-aided wireless powered cooperative communication network (WPCCN), in which the source and relay harvest the energy from a dedicated power beacon via wireless energy transfer, then the source transmits the data to the destination through the relay. Both the source and relay are equipped with an energy buffer to store the harvested energy in the energy transfer stage. In addition, the relay is equipped with a data buffer and can temporarily store the received information. Considering the buffer-aided WPCCN, we propose two buffer-aided relaying protocols, which named as the buffer-aided harvest-then-transmit (HtT) protocol and the buffer-aided joint mode selection and power allocation (JMSPA) protocol, respectively. For the buffer-aided HtT protocol, the time-averaged achievable rate is obtained in closed form. For the buffer-aided JMSPA protocol, the optimal adaptive mode selection scheme and power allocation scheme, which jointly maximize the time-averaged throughput of system, are obtained by employing the Lyapunov optimization theory. Furthermore, we drive the theoretical bounds on the time-averaged achievable rate and time-averaged delay, then present the throughput-delay tradeoff achieved by the joint JMSPA protocol. Simulation results validate the throughput performance gain of the proposed buffer-aided relaying protocols and verify the theoretical analysis.

Low-Complexity Energy Efficient Base Station Cooperation Mechanism in LTE Networks

  • Yu, Peng;Feng, Lei;Li, Zifan;Li, Wenjing;Qiu, Xuesong
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제9권10호
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    • pp.3921-3944
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    • 2015
  • Currently Energy-Saving (ES) methods in cellular networks could be improved, as compensation method for irregular Base Station (BS) deployment is not effective, most regional ES algorithm is complex, and performance decline caused by ES action is not evaluated well. To resolve above issues, a low-complexity energy efficient BS cooperation mechanism for Long Time Evolution (LTE) networks is proposed. The mechanism firstly models the ES optimization problem with coverage, resource, power and Quality of Service (QoS) constraints. To resolve the problem with low complexity, it is decomposed into two sub-problems: BS Mode Determination (BMD) problem and User Association Optimization (UAO) problem. To resolve BMD, regional dynamic multi-stage algorithms with BS cooperation pair taking account of load and geographic topology is analyzed. And then a distributed heuristic algorithm guaranteeing user QoS is adopted to resolve UAO. The mechanism is simulated under four LTE scenarios. Comparing to other algorithms, results show that the mechanism can obtain better energy efficiency with acceptable coverage, throughput, and QoS performance.

Impact of Revenue Sharing Contract on the Performance of Vendor

  • Chungsuk RYU
    • 산경연구논집
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    • 제14권9호
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    • pp.21-30
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    • 2023
  • Purpose: Focusing on the role of the special contract to collaborate the supply chain operations, this study investigates how the revenue sharing contract affects the performance of Vendor Managed Inventory (VMI). Research design, data, and methodology: The optimization model is formulated to represent two stage supply chain system where the supplier and retailer manage the operations to maximize their own profits. Three supply chain models including the traditional system, VMI, and VMI with revenue sharing contract are compared in the numerical examples. Results: According to the numerical analysis, the entire supply chain system has greater profit under VMI than the traditional system, while VMI alone sacrifices the supplier's profit. With the proper sets of revenue share ratio and wholesale price discount rate, VMI with revenue sharing contract results in the increased profit for both supplier and retailer compared with VMI alone as well as the traditional system. Conclusions: The numerical examples imply that VMI, when it is combined with the revenue sharing contract, can be the effective collaboration program that satisfies every supply chain member. To make VMI with revenue sharing contract to be fair to all supply chain members, they need to agree on the appropriate contract content.

쏘일네일링의 세 가지 파괴모드를 고려한 설계 최적화에 대한 연구 (Optimization of Soil-Nailing Designs Considering Three Failure Modes)

  • 서형준;이강현;박정준;이인모
    • 한국지반공학회논문집
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    • 제28권7호
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    • pp.5-16
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    • 2012
  • 쏘일네일링 공법은 흙막이 또는 사면안정을 위해서 가장 많이 사용되는 공법이다. 일반적으로 쏘일네일링 공법의 설계에서는 인발에 의한 파괴와 전단에 의한 파괴를 고려한다. 쏘일네일링의 파괴거동은 인발파괴와 전단파괴와 같이 파괴면을 가지면서 사면이 무너지는 경우도 발생하지만 굴착에 의해서 사면 표면의 수평응력이 감소함에 따라 점점 표면이 쓸려가는 얕은 파괴에 의해서 파괴에 이르는 경우가 실제 현장에서 자주 발생하게 된다. 따라서 쏘일네일링의 파괴거동을 크게 인발파괴, 전단파괴, 그리고 얕은파괴로 나누어 정의하였다. 본 논문에서는 각각의 파괴모드에 대한 제약조건을 이론적으로 산정하였다. 또한 각각의 파괴를 막기 위한 설계 최적화를 실시하였으며, 네일링의 정착길이, 개수, 그리고 얕은파괴를 막기 위한 전면에서의 최소 구속압을 설계변수로 두어 최적화 과정을 진행하였다. 최적화 과정은 먼저 네일링의 정착길이와 인장력을 설계변수로 하여 인발파괴 및 전단파괴에 대하여 최적화를 실시한다. 다음으로 각 굴착단계별 사면의 표면에서 얕은파괴를 막기 위한 최소의 구속압을 산정한 후 최적화를 반복수행하여 각각의 설계 변수를 산정하게 된다. 이와 같은 설계 최적화 프로그램을 통해서 인발파괴와 전단파괴만을 고려하는 기존의 설계 시스템에서 프리스트레스까지 산정할 수 있게 되었다.