• Journal of the Korean Geotechnical Society
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• v.39 no.5
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• pp.27-40
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• 2023

A pile is a structural element that is used to transfer external loads from superstructures and has been widely utilized in construction fields all over the world. The method of installing a pile into the ground should be selected based on geotechnical conditions, location, site status, environmental factors, and construction costs, among others. It can be divided into two types: direct hammering and preboring. The direct hammering method installs a pile into the bearing layer, such as rock, using a few types of hammer, generating a considerable amount of pile driving-induced vibration. The vibration from pile driving influences adjacent structures and the ground; therefore, quantitatively investigating the effects of vibration is inevitably required. In this study, two-dimensional dynamic numerical modeling and analysis are performed using the finite difference method to investigate the influence on the adjacent slope, including temporary supporting system. Time-dependent loading induced by pile driving is estimated and used in the numerical analysis. Consequently, large surface displacement is estimated due to surface waves and less wave deflection, and refraction at the surface. The total displacement decreases with the increase of the distance from the source. However, lateral displacement at the top of the slope shows a larger value than vertical displacement, and the overall displacement tends to be concentrated near the face of the slope.

• Journal of Christian Education in Korea
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• v.72
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• pp.317-339
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• 2022

The purpose of this study is to develop liberal arts subjects for humanity education in Christian universities. Christian universities need to attempt Christian humanity education through Christian educational interpretation of humanity. This study defines the humanity not character or personality but rather humanity. Humanity is starting from an understanding of human conditions. And it is a perspective toward oneself and others based on human ontological questions and life style. Human is a being with developmental crises and are marginal being with existential anxiety. Therefore, humanity education of Christian universities should be a place to face the void of finite humans in order to understand what kind of existence they are and to transform their epistemology to understand self and the world. Christian humanity education will be realized by two approaches. The first is a theoria approach that extends from a two-dimensional understanding of the self and experienced reality to the speculative and introspective pursuit of the ultimate truth, The second is a praxis approach that consist of the interaction of reflection to human's act and reflective behavior. Therefore, this study develops a subject focused on a speculative and reflective understanding of humanity as an case of a liberal arts subject for humanity education in a Christian university, and a subject focusing on the understanding of reflexively participating in the actual social situation, which is the context of humanity.

• Journal of Korea Water Resources Association
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• v.56 no.1
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• pp.23-34
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• 2023

This study analyzed the bed load transport and channel change on the vegetation zone through laboratory experiments and numerical simulations. To examine the effect of vegetation zone in the laboratory experiment, artificial vegetation zones made of acrylic sticks were installed in the experimental channel, and discharge conditions were adjusted to examine the bed load transport and channel change in the vegetation zone. Next, numerical simulations were performed by applying the same conditions as those of the laboratory experiment to the Nays2D model, a two-dimensional numerical model, and the applicability of the numerical model was examined by comparing the results with the results of the laboratory experiment. Finally, by applying a numerical model, the bed load transport and channel change according to the change in vegetation density were examined. As a result of examining the bed load transport and channel change in the vegetation zone according to the discharge condition change by applying the laboratory experiment and the numerical model, the results of the two application methods were similar. As the discharge increased, bed load from the upper stream was deposited inside the vegetation zone. On the other hand, on the other side of the vegetation zone, the flow was concentrated and erosion occurred. Also, the range of erosion increased in the downstream direction. As a result of examining the bed load transport and channel change according to the change in vegetation density, as the vegetation density increased, the bed load from the upper stream was deposited inside the vegetation zone. On the other hand, due to the increase in vegetation density, the flow was concentrated to the opposite side of the vegetation zone, erosion occurred.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.2D
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• pp.299-309
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• 2006

Railway noise and vibration has been recognized as major problems with the speed-up of rolling stock. As a kind of solution to these problems, the decrease of stiffness of track pad have been tried. However, in this case, overturning of rail due to lateral force should be considered because it can have effect on the safety of running train. Therefore, above two things - decrease of stiffness of track pad and overturning of rail due to lateral force - should be considered simultaneously for the appropriate determination of spring coefficient of track pad. With this viewpoint, minimum spring coefficient of track pad is estimated through the comparison between the theoretical relationship about the overturning of rail and 3-dimensional FE analysis result. Two kinds of Lateral force and wheel load are used as input loads. Extracted values from the conventional estimation formula and the Shinkansen design loads are used. It is found that the overturning of rail changes corresponding to the change of the stiffness of track pad and the ratio of lateral force to wheel load. Moreover, it is found that the analysis model can have influence on the results. Through these procedure, minimum spring coefficient of track pad is estimated.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.2B
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• pp.211-217
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• 2010

This paper presents numerical investigations of the physical habitat changes induced by the hydropeaking in the downstream river of dam. For the two-dimensional ecohydraulic simulations, River2D model is used. Pirami (Zacco platypus) is selected as the target fish for investigating the impact of the hydropeaking. For validation of the model, the water surface elevations are simulated with two different water discharges. The computed results are compared with field data in the literature, and the result shows that the model successfully simulates the water flows. The weight usable area (WUA) of Pirami with the life cycle and the composite suitability index with different water discharges are computed and discussed. The results show that habitat for Pirami appears to be best in the bend region downstream of the dam. The discharge of the maximum WUA for adult Pirami is computed to be about 9 $m^3/s$. Also, the WUA computed in a condition of hydropeaking during seven days are presented. The averaged discharge of the hydropeaking appears to be about 20% larger than the drought flow, but the WUA by the hydropeaking is computed to be 60-100% smaller. This result shows that the hydropeaking reduces quantity of habitat available to fish.

• Journal of Microbiology and Biotechnology
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• v.33 no.8
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• pp.1023-1029
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• 2023

Biosurfactants reduce surface and interfacial tension due to their amphiphilic properties and are an eco-friendly alternative for chemical surfactants. In this study, a new yeast strain JAF-11 that produces a biosurfactant was selected using drop collapse method, and the properties of the extracts were investigated. The nucleotide sequences of the strain were compared with closely related strains and identified based on the D1/D2 domain of the large subunit ribosomal DNA (LSU) and internal transcribed spacer (ITS) regions. Neodothiora populina CPC 39399^T, the closest species with strain JAF-11, showed a sequence similarity of 97.75% for LSU and 94.27% for ITS, respectively. The result suggests that the strain JAF-11 represents a distinct species that cannot be assigned to any existing genus or species in the family Dothideaceae. Strain JAF-11 produced a biosurfactant reducing the surface tension of water from 72 mN/m to 34.5 mN/m on the sixth day of culture and the result of measuring the critical micelle concentration (CMC) by extracting the crude biosurfactant was found to be 24 mg/l. The molecular weight 502 of the purified biosurfactant was confirmed by measuring the fast atom bombardment mass spectrum. The chemical structure was analyzed by measuring ¹H nuclear magnetic resonance (NMR), ¹³C NMR, and two-dimensional NMRs of the compound. The molecular formula was C₂₆H₄₆O₉, and it was composed of one octanoyl group and two hexanoyl groups to myo-inositol moiety. The new biosurfactant is the first report of a compound produced by a new yeast strain, JAF-11.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.16 no.5
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• pp.354-361
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• 2023

Big data analysis systems apply NoSQL databases like MongoDB to store, process, and analyze diverse forms of large-scale data. MongoDB offers scalability and fast data processing speeds through distributed processing and data replication, depending on its configuration. This paper investigates the suitable MongoDB environment configurations for implementing big data analysis systems. For performance evaluation, we configured both single-node and multi-node environments. In the multi-node setup, we expanded the number of data nodes from two to three and measured the performance in each environment. According to the analysis, the processing speeds for complex data structures with three or more dimensions are approximately 5.75% faster in the single-node environment compared to an environment with two data nodes. However, a setting with three data nodes processes data about 25.15% faster than the single-node environment. On the other hand, for simple one-dimensional data structures, the multi-node environment processes data approximately 28.63% faster than the single-node environment. Further research is needed to practically validate these findings with diverse data structures and large volumes of data.

• Journal of the Korean Chemical Society
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• v.68 no.3
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• pp.151-159
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• 2024

Indian spices are well known for their numerous health benefits, flavour, taste, and colour. Recent Advancements in chemical technology have led to better extraction and identification of bioactive molecules (phytochemicals) from spices. The therapeutic effects of spices against diabetes, cardiac problems, and various cancers has been well established. The present in silico study aims to investigate the binding affinity of 29 phytochemicals from 11 Indian spices with two prominent proteins, BCL3 and CXCL10 involved in invasiveness and bone metastasis of breast cancer. The three-dimensional structures of 29 phytochemicals were extracted from PubChem database. Protein Data Bank was used to retrieve the 3D structures of BCL3 and CXCL10 proteins. The drug-likeness and other properties of compounds were analysed by ADME and Lipinski rule of five (RO5). All computational simulations were carried out using Autodock 4.0 on Windows platform. The proteins were set to be rigid and compounds were kept free to rotate. In-silico study demonstrated a strong complex formation (positive binding constants and negative binding energy ΔG) between all phytochemicals and target proteins. However, piperine and sesamolin demonstrated high binding constants with BCL3 (50.681 × 10³ mol^-1, 137.76 × 10³ mol^-1) and CXCL10 (98.71 × 10³ mol^-1, 861.7 × 10³ mol^-1), respectively. The potential of these two phytochemicals as a drug candidate was highlighted by their binding energy of -6.5 kcal mol^-1, -7.1 kcal mol^-1 with BCL3 and -6.9 kcal mol^-1, -8.2 kcal mol^-1 with CXCL10, respectively coupled with their favourable drug likeliness and pharmacokinetics properties. These findings underscore the potential of piperine and sesamolin as drug candidates for inhibiting invasiveness and regulating breast cancer metastasis. However, further validation through in vitro and in vivo studies is necessary to confirm the in silico results and evaluate their clinical potential.

• Korean Journal of Radiology
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• v.22 no.1
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• pp.118-130
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• 2021

Objective: This study aimed to investigate the blood-brain barrier (BBB) disruption in mild traumatic brain injury (mTBI) patients with post-concussion syndrome (PCS) using dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging and automatic whole brain segmentation. Materials and Methods: Forty-two consecutive mTBI patients with PCS who had undergone post-traumatic MR imaging, including DCE MR imaging, between October 2016 and April 2018, and 29 controls with DCE MR imaging were included in this retrospective study. After performing three-dimensional T1-based brain segmentation with FreeSurfer software (Laboratory for Computational Neuroimaging), the mean K^trans and v_p from DCE MR imaging (derived using the Patlak model and extended Tofts and Kermode model) were analyzed in the bilateral cerebral/cerebellar cortex, bilateral cerebral/cerebellar white matter (WM), and brainstem. K^trans values of the mTBI patients and controls were calculated using both models to identify the model that better reflected the increased permeability owing to mTBI (tendency toward higher K^trans values in mTBI patients than in controls). The Mann-Whitney U test and Spearman rank correlation test were performed to compare the mean K^trans and v_p between the two groups and correlate K^trans and v_p with neuropsychological tests for mTBI patients. Results: Increased permeability owing to mTBI was observed in the Patlak model but not in the extended Tofts and Kermode model. In the Patlak model, the mean K^trans in the bilateral cerebral cortex was significantly higher in mTBI patients than in controls (p = 0.042). The mean v_p values in the bilateral cerebellar WM and brainstem were significantly lower in mTBI patients than in controls (p = 0.009 and p = 0.011, respectively). The mean K^trans of the bilateral cerebral cortex was significantly higher in patients with atypical performance in the auditory continuous performance test (commission errors) than in average or good performers (p = 0.041). Conclusion: BBB disruption, as reflected by the increased K^trans and decreased v_p values from the Patlak model, was observed throughout the bilateral cerebral cortex, bilateral cerebellar WM, and brainstem in mTBI patients with PCS.

• The Korean Journal of Applied Statistics
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• v.37 no.2
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• pp.209-224
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• 2024

Speaker verification is becoming popular as a method of non-face-to-face identity authentication. It involves determining whether two voice data belong to the same speaker. In cases where the criminal's voice remains at the crime scene, it is vital to establish a speaker verification system that can accurately compare the two voice evidence. In this study, to achieve this, a new speaker verification system was built using a deep learning model for Korean language. High-dimensional voice data with a high variability like background noise made it necessary to use deep learning-based methods for speaker matching. To construct the matching algorithm, the ECAPA-TDNN model, known as the most famous deep learning system for speaker verification, was selected. A large dataset of the voice data, Voxceleb, collected from people of various nationalities without Korean. To study the appropriate form of datasets necessary for learning the Korean language, experiments were carried out to find out how Korean voice data affects the matching performance. The results showed that when comparing models learned only with Voxceleb and models learned with datasets combining Voxceleb and Korean datasets to maximize language and speaker diversity, the performance of learning data, including Korean, is improved for all test sets.