• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2002.10a
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• pp.171-171
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• 2002

Recent industrial society has human widely exposed to PAHs that are comming from the incomplete combustion of organic material as widerspread environmetal contaminants. Biological activities of PAHs are not known although PAHs are considered as carcinogens. PAHs in the mammalian cells affect CYP1A1 gene expression as well as other phase II drug metabolizing enzymes as UDPGT, NMOR etc. The mechanism of action of PAHs has been studied extensively, however it is not clear how PAHs turn on CYP1A1 in human breast cancer. Our labolatory have been studied the effect of PAHs in the human breast cancer cell lind MCF7. In this study, we examined the ZR-75-1 human breast cancer cells as a new system to evaluate bioactivity of PAHs. ZR-75-1 human breast cancer cell line has been estabilished from the breast cnacer patient, has estrogen receptors and progesteron receptors. We have been able to estbilish long term culture system of this cells then used for the study to observe the effect of PAHs. We demonstrate that PAHs induced the transcription of an aryl hydrocarbon-responsive reporter vector containing the CYP1A1 promoter and 7-ethoxyresolufin O-deethylase(EROD) activity of CYP1A1 enzyme in a concentration-dependant manner. RT-PCR analysises indicated that PAHs significantly up-regulate the constitutive level of CYP1A1 mRNA. Apparently, ZR-75-1 cells have Aryl hydrocarbon recetors, therefore it would be good experimental tool to study the cross-talk between PAHs and steroid actions.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.18 no.1
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• pp.116-121
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• 2009

Thermosonic flip chip bonding is an important technology for the electronic packaging due to its simplicity, cost effectiveness and clean and dry process. Mechanical properties of the horn and the shank, such as the natural frequency and the amplitude, have a great effect on the bonding capability of the transverse flip chip bonding system. In this research, two kinds of study are performed. The first is the new design of the clamp and the second is the effect of tolerance parameters to the performance of the system. The clamp with a bent shape is newly designed to hold the nodal point of the flip chip. The second is the effect of the design parameters on the vibration amplitude and planarity at the end of the shank. The variation of the tolerance parameters changes the amplitude and the frequency of the vibration of the shank. They, in turn, have an effect on the quantity of the plastic deformation of the gold ball bump, which determined the quality of the flip chip bonding. The tolerance parameters that give the great effect on the amplitude of the shank are determined using Taguchi's method. Error of set-up angle, the length and diameter of horn and error of the length of the shank are determined to be the parameters that have peat effect on the amplitude of the system.

• 한국지구물리탐사학회:학술대회논문집
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• 1999.08a
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• pp.37-47
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• 1999

Among the geophysical exploration methods, electromagnetic (EM) survey must have the broadest range of instrumental systems and remarkable range of applications. There is a plethora of available techniques and instruments, and the depth of investigation and resolution are highly dependent on the particular systems used according to their operating frequency and source-receiver configuration. This diversity of EM systems, however, provides a wide range of instruments or methodologies to choose in order to select the most appropriate tool for the task in hand. This rather than being a disadvantage, would be a major strength of EM methods. Modern EM equipments are remarkably portable, considering their sophistication. Coupled with major advances in recent computer technology, accurate modeling and interpretation techniques are on the way of continuous development and upgrade which, in turn, make the EM methods to become much more heavily used, especially for engineering and environmental applications. We aim to provide a brief theoretical principles, survey techniques and case histories of some selected EM methods that can be applied to geotechnical and environmental problems in Korea.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.34 no.4
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• pp.179-188
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• 2011

This paper outlines a systematic guideline for remanufacturing process using the Failure Mode and Effect Analysis (FMEA) method in order to estimate the reliability and quality of the remanufactured alternator. The method is just a tool to help, but the remanufacturer must determine the optimal remanufacturing process and specific inspection and production that will turn the alternator as-good-as new and place the product into the market with reliability and quality equal to a new product. FMEA is a method that is widely used in industry and has shown its value and effectiveness in the above remanufacturing case study. Actions taken often result in a lower severity, occurrence or detection rating. Redesign may result in lower severity and occurrence ratings while inserting validation controls and maintenance can reduce the detection rating. The revised ratings are recorded with the originals on the FMEA template form. After these corrective actions and revisions have been established, evaluation of the ranks can be repeated, until the redesign and control parameters comply with safety standards.

• Journal of Information Technology Applications and Management
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• v.24 no.3
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• pp.1-21
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• 2017

Business Intelligence (BI) system is a strategic tool that presents an analytical perspective about business and external environments. Even though its strategic value was well known, users often avoid using it or adopt it ceremonially. In fact, over 50 per cent of BI projects worldwide are reported to end in failure. Such an unexpectedly lower success rate has been a key issue in BI studies. In order to enhance a proper use of information systems, MIS field provided a number of theoretical constructs. One example is Goodhue & Thompson's Task-Technology Fit (TTF). In addition, internalization, the degree to which people make their own effort to modify behavior, was recently suggested as another important determinant of use. Though in MIS community both TTF and internalization proved to be a key determinant of system use, there has been not much study aiming to discover antecedents influencing these constructs. In this study we assert that user participation should be highlighted in BI projects. Especially, we emphasize user participation at the phase of feasibility study that is mainly conducted to determine whether a BI system is essentially necessary and practicable. Our research model employs participative feasibility study as a major antecedent for TTF and internalization that consequently will lead to user satisfaction and actual use. This model was empirically tested on 121 BI system users. The result shows that user participation in feasibility study is positively associated with TTF and internalization, each being related to user satisfaction and system use. It implies that, if an organization has BI users get involved in strategic feasibility study phase, the BI system would turn out to fit users' tasks and, furthermore, users would put more efforts spontaneously in order to use it properly.

• Journal of the Korean Society for Library and Information Science
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• v.52 no.1
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• pp.313-340
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• 2018

The purpose of this study was to design a PCSI model that can be applicable to measurement of library user satisfactions, which can be used in evaluating organizational performance. The National Assembly Library (NAL) was selected as a case to design a PCSI-based model and to test the model by conducting a self-administered survey of 341 internal and external library users. The model was validated to have a satisfactory model fit. Fitting the model, the study confirms that the service qualities of the NAL affect user satisfactions, which in turn affects organizational performances. The PCSI score of the library was 80.4, which can be used as a useful index that can compare the library's performance with other organizations in the similar public domain. Major contributions of this study are two-fold: the PCSI-based model proposed in this study provides a theoretical basis that assesses organizational performance of libraries via user satisfaction; and libraries can utilize the model as a management tool to assess the organizational performance from the user perspective.

• Journal of The Geomorphological Association of Korea
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• v.19 no.4
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• pp.139-155
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• 2012

Most of previous landform classification methods using DEM compares the values between the center of the cell and the surrounding cells, which in turn, greatly depends on analysis scale. To overcome the problem of scale-dependency, a new classification scheme is developed, which is called "Geomorphons". Unlike the traditional approaches using DEM, Geomorphons is the way which compares the level with other cells against the criteria cell. As a pilot study, we classify the landforms of Pyeongchang-Gun in Korea. Then, we compare the result with the other methods such as Topographic Position Index. Through the systematic analysis, we obtain the following findings. First, Geomorphons can reduce the time for the classification of landforms because of using unsupervised classification. Second, Geomorphons is little dependent on change in the scale, which can provide a pilot tool for reconnaissance study for covering large area.

• Journal of the Korea Society of Computer and Information
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• v.25 no.6
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• pp.131-141
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• 2020

In this paper, we propose a model that explains how the quality of YouTube clip and the credibility in YouTuber affect the usefulness of information and attitude of adapting information, based on 'Information Adoption Model' proposed by Sussman and Siegal. Additionally, we investigate the moderating role of YouTube genre in this model. Empirical analysis has shown that both the quality of YouTube clip and the credibility in YouTuber in the entire genre have a significant impact on the usefulness of information, which in turn significantly affects the attitude of information adoption. But only the quality in YouTube clip is found to have a significant impact in the 'information-oriented' genre, whereas, in the 'entertainment-oriented' genre, only the credibility in YouTuber is found to have a significant impact. The findings of our study provide various implications for building a business strategy for using YouTube as an information providing tool.

• Journal of Soil and Groundwater Environment
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• v.25 no.2_spc
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• pp.86-100
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• 2020

Analyzing and monitoring environmental contaminants based on geophysical exploration techniques have become important and it is now widely applied to delineate spatial distribution geophysical characteristics in wide area. Among the techniques, induced polarization (IP) method, which measures polarization effects on electrical potential distribution, has drawn much attention as an effective tool for environmental monitoring since IP is sensitive to changes in biochemical reactions. However, various reactions stemming from the presence of multiple contaminants have greatly enhanced heterogeneity of polluted sites to result in highly variable electrical characteristics of the site. Those contaminants influence chemical and physical state of soil and groundwater to alter electrical double layer, which in turn influences polarization of the media. Since biochemical reactions between microbes and contaminants result in various IP effects, IP laboratory experiments were conducted to investigate IP responses of the contaminated soil samples under various conditions. Field IP surveys can delineate the spatial distribution of contamination, while providing additional information about electrical properties of a target medium, together with DC resistivity. Reviewing IP effects of contaminants as well as IP surveys can serve as a good starting point for the application of IP survey in site assessment for environmental remediation.

• Journal of Korean Society on Water Environment
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• v.27 no.4
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• pp.445-460
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• 2011

The objective of this study was to construct and assess the applicability of the EFDC model for Saemangeum Reservoir as a 3D hydrodynamic and water quality modeling tool that is necessary for the effective management of water quality and establishment of conservation measures. The model grids for both reservoir system only and reservoir-ocean system were created using the most recent survey data to compare the effects of different downstream boundary conditions. The model was applied for the simulations of temperature, salinity, water quality variables including chemical oxygen demand (COD), chlorophyll-a (Chl-a), phosphorus and nitrogen species and algal biomass, and validated using the field data obtained in 2008. Although the model reasonably represented the temporal and spatial variations of the state variables in the reservoir with limited boundary forcing data, the salinity level was underestimated in the middle and upstream of the reservoir when the flow data were used at downstream boundaries; Sinsi and Garyuk Gates. In turn, the error caused to increase the bias of water quality simulations, and inaccurate simulation of density flow regime of river inflow during flood events. It is likely because of the loss of momentum of sea water intrusion at downstream boundaries. In contrast to flow boundary conditions, the mixing between sea water and freshwater was well reproduced when open water boundary condition was applied. Thus, it is required to improve the downstream boundary conditions that can accommodate the real operations of the sluice gates.