• Asian-Australasian Journal of Animal Sciences
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• 제13권10호
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• pp.1445-1449
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• 2000

A total of one hundred twenty pigs ($L{\times}Y{\times}D$, $50{\pm}0.78kg$) were employed for a 7-week feeding trial to determine the effect of inclusion levels of vitamin and mineral (VTM) premixes on growth performance, nutrient digestibility and pork stability in finishing pigs. Treatments were 100% (Control), 150%, 200%, and 250% of NRC (1998) requirements. Increasing dietary VTM premixes in finishing pigs had a linear (p<0.05) effect on ADG. It also had a linear effect (p<0.05) on the digestibility of calcium and a linear and quadratic effect (p<0.05) on the digestibility of phosphorus. As dietary VTM levels were increased from 100 to 250% NRC (1998), TBARS values of pork samples were linearly (p<0.05) lowered when stored at $1^{\circ}C$ for 2 or 3 weeks. There was also a trend reducing POV of pig meat as dietary VTM level was increased. In conclusion, it would appear that inclusion of VTM premixes at the level of 200-250% of NRC (1998) requirements gave positive effects on growth performance and pork stability in finishing pigs.

• 한국산학기술학회논문지
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• 제13권3호
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• pp.1008-1013
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• 2012

EHPS는 탈엔진형 조향기술로 BLDC 모터를 통해 유압펌프를 작동시켜 조향력을 보조하는 동력 조향장치이다. EHPS는 BLDC 모터, 기어펌프 및 유압회로, 파워 스티어링 등으로 이루어진 전기전자, 유압 및 기계시스템의 복합적 시스템으로 모델링이 어렵다. 본 논문에서는 EHPS 시스템의 구성 부품을 수학적 모델링 하였고, AMESim을 이용하여 multi-domain 시스템의 시뮬레이션 모델을 구축하였다. 이를 활용한 다양한 시뮬레이션을 통해 개발 초기단계에서의 시행착오를 줄이고 완성도 높은 EHPS 개발 업무를 수행하는 데 도움을 줄 수 있을 것으로 사료된다.

• 대한한의학원전학회지
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• 제23권4호
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• pp.39-62
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• 2010

Background : I investigated clinical research methodology of Traditional Korean Medicine(TKM) for treatment of lung cancer with Evidence Based Medicine(EBM) approach. Methods : I conducted the internet search of National Central Library, the National Assembly Library, Korea Education & Research Information Service, Korea Institute of Science and Technology Information for Korean theses and papers, and MEDLINE for the outside articles. Conclusion : In addition to outcomes of clinical trial, abundant clinician's experience and patients' preference are also considered. Pragmatic trials and quasi-experimental trials are better than clinical trials to plan clinical design of TKM for lung cancer and appropriate endpoints includes overall survival, disease-free survival, patient reporting outcome.

• Journal of Ginseng Research
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• 제37권1호
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• pp.30-36
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• 2013

The aim of this review was to assess the effectiveness of ginseng as a treatment option for managing menopause symptoms. We searched the literature using ll databases from their inception to 26 September 2012 and included all randomised clinical trials (RCTs) that compared any type of ginseng to a placebo controls in postmenopausal women. The methodological quality of all studies was assessed using a Cochrane risk of bias tool. Four RCTs met our inclusion criteria. Most RCTs had high risk of bias. One RCT showed that Korean red ginseng (KRG) significantly improved sexual arousal and global health compared with placebo. Another RCT reported the superiority of KRG over placebo for treating menopause symptoms on Kupperman's index and menopausal rating score. The third RCT failed to show a significant effect of KRG on hot flash frequency compared to placebo. The fourth RCT found beneficial effects of ginseng compared to placebo on depression and well-being. In conclusion, the evidence on ginseng as an effective treatment for managing menopause symptoms is limited. Most of the RCTs are burdened with a high risk of bias. Thus firm conclusions cannot be drawn. Rigorous studies seem warranted.

• 대한예방한의학회지
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• 제15권2호
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• pp.51-67
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• 2011

The average human life span has increased due to the development of modern medicine and science, resulting in prolonged life expectancy and increase in the population counts of the geriatric age group. In particular, a dramatic increase of elderly patients suffering from senile disorders including neurodegenerative diseases, Alzheimer's disease(AD), and vascular dementia has become a serious social problem in public health. Thus, this study is aimed to summarize available clinical trial data on several commonly used medicines include donepezil, rivastigmine, galantamine, memantine and oriental medicine, and examine the effect of oriental medicine combined with western medicine in the treatment of patients with senile disorders using the data from literature reviews and survey studies.

• Journal of Gastric Cancer
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• 제20권1호
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• pp.1-18
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• 2020

Splenic hilar lymph node dissection has been the standard treatment for advanced proximal gastric cancer. Splenectomy is typically performed as part of this procedure. However, splenectomy has some disadvantages, such as increased risk of postoperative complications, especially pancreatic fistula. Moreover, patients who underwent splenectomy are vulnerable to potentially fatal infection caused by encapsulated bacteria. Furthermore, several studies have shown an association of splenectomy with cancer development and increased risk of thromboembolic events. Therefore, splenectomy should be avoided if it does not confer a distinct oncological advantage. Most studies that compared patients who underwent splenectomy and those who did not failed to demonstrate the efficacy of splenectomy. Based on the results of a randomized controlled trial conducted in Japan, prophylactic dissection with splenectomy is no longer recommended in patients with gastric cancer with no invasion of the greater curvature. However, patients with greater curvature invasion or those with remnant gastric cancer still need to undergo splenectomy to facilitate splenic hilar node dissection. Spleen-preserving splenic hilar node dissection is a new procedure that may help delink splenic hilar node dissection and splenectomy. In this review, we examine the evidence pertaining to the efficacy and disadvantages of splenectomy. We discuss the possibility of spleen-preserving surgery for prophylactic splenic hilar node dissection to overcome the disadvantages of splenectomy.

• 생약학회지
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• 제9권4호
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• pp.177-180
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• 1978

In oriental medicine, Coptis japonica $M_{AKINO}$ (Ranunculaceae) has been known as bitter stomachics. This plant originally grows wild and has been cultivated in Japan but not in Korea. However, a few years ago, some workers have been trying to cultivate this plant in Korea and have made much progress. Therefore, this . study was made for the purpose of conforming possibility in cultivation of Coptis japonica $M_{AKINO}$ in Korea. The results were as follows: 1) Berberine contents of rhizomes are much more than of K.P.. Difference in contents between Eu Jeon Bu $(4.88{\pm}0.77%)$ and Bo Seong area $(3.62{\pm}0.50%)$ is significant (p<0.05). 2) Berberine contents of fibrous roots of Eu jeong Bu $(0.97{\pm}0.28%)$ area was similar to that of Gang Nam $(0.93{\pm}0.21%)$, Yang Pyung area $(0.91{\pm}0.14%)$ but only contents of Bo Seong area $(0.74{\pm}0.25%)$ is less than that of other area and it's difference is not significant. 3) It was considered that the cultivation of Coptis japonica $M_{AKINO}$ in Korea is possible considering the cultivation results and berberine contents, and also more moderate than south region.

• The Journal of Korean Physical Therapy
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• 제29권2호
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• pp.74-79
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• 2017

Purpose: The purpose of this study was to compare the effects of the FES-gait with augmented feedback training to the FES alone on the gait and functional performance in individuals with chronic stroke. Methods: This study used a pretest and posttest randomized control design. The subjects who signed the agreement were randomly divided into 12 experimental groups and 12 control groups. The experimental groups performed two types of augmented feedback training (knowledge of performance and knowledge of results) together with FES, and the control group performed FES on the TA and GM without augmented feedback and then walked for 30 minutes for 40 meters. Both the experimental groups and the control groups received training five times a week for four weeks. Results: The groups that received the FES with augmented feedback training significantly showed a greater improvement in single limb support (SLS) and gait velocity than the groups that received FES alone. In addition, timed up and go (TUG) test and six minute walk test (6MWT) showed a significant improvement in the groups that received FES with augmented feedback compared to the groups that received FES alone. Conclusion: Compared with the existing FES gait training, augmented feedback showed improvements in gait parameters, walking ability, and dynamic balance. The augmented feedback will be an important method that can provide motivation for motor learning to stroke patients.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2009년도 세계 도시지반공학 심포지엄
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• pp.1511-1516
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• 2009

In recent years, the large-scale shaft have been appling in domestic mine for mass production using a large machine, the safety of mine also have been increasing. And the new trial that shotcrete of tunnel field was apply to mine support was progressed. But, the conditions of domestic mine was different from that of tunnel, so, the batch plant of tunnel could not be installed in mine field because of low economical efficiency and difficulty for selection of site. Ready-mixed Shotcrete that mixed with high quality materials and could be controled shotcrete quality is producted in plants and transported to field, so do not need to batch plant. In this study, The Field test of the Ready-mixed Shotcrete was performed in the large-scale mine and was compared with the quality of Field mix shotcrete. As the result of the Field test, compressive strength and rebound of Ready-mixed Shotcrete were superior to these of Field mix shotcrete.

• 대한방사성의약품학회지
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• 제8권2호
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• pp.113-118
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• 2022

Gadolinium neutron capture therapy (Gd-NCT) is a precision radiation therapy that kills cancer cells using the neutron capture reaction that occurs when ¹⁵⁷Gd hits thermal neutrons. ¹⁵⁷Gd has the highest thermal neutron capture cross section of 254,000 barns among stable isotopes in the periodic table. Another stable isotope, ¹⁵⁵Gd, also has a high thermal neutron trapping area (~ 60,700 barns), so gadolinium that exists in nature can be used as a Gd-NCT drug. Gd-NCT is a mixed kinetic energy of low-energy and high-energy ionizing particles, which can be uniformly distributed throughout the tumor tissue, thereby solving the disadvantage of heterogeneous dose distribution in tumor tissue. The Gd complexes of small-sized molecule are widely used as contrast agents for magnetic resonance imaging (MRI) in clinical practice. Therefore, these compounds can be used not only for diagnosis but also therapy when considering the concept of Gd-NCT. This multifunctional trial can look forward to new medical advance into NCT clinical practices. In this review, we introduce gadolinium compounds suitable for Gd-NCT and describe the necessity of image guided Gd-NCT.