• 한국산학기술학회논문지
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• 제19권10호
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• pp.231-242
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• 2018

이 연구는 대기업 사무직 근로자에게 적용한 원예활동 프로그램의 정신적, 생리적 효과를 확인하기 위해서 시행되었다. 53명의 사무직 근로자가 연구에 참여하였다. 참여 대상자들은 2그룹(실험군과 대조군)으로 무작위 할당되었다. 무작위 할당은 Microsoft사의 Excel 2010 program RAND 함수를 이용하여 시행되었다. 8주 실험 동안 실험군에게 1회기 당 90분씩 원예활동 프로그램을 적용하였다. 대조군에게는 아무런 처치를 하지 않았다. 실험 전과 실험 8주 후에 모든 대상자들의 변수들(스트레스, 우울, 혈당, 총콜레스테롤, HDL-C, LDL-C)을 측정하였다. 실험 전부터 실험 완료 후까지 변수들의 변화가 계산되었다. 자료는 2014년 7월부터 9월까지 수집되었다. SPSS 21.0이 통계 분석에 이용되었다. 원예활동 프로그램이 우울에 긍정적인 효과를 가졌다(z=-4.57, p< .000). 결론은 원예활동 프로그램은 우울을 향상시키는 긍정적인 효과를 가진다는 것이다. 원예활동 프로그램이 사무직 근로자의 정신 건강 증진을 위한 보완대체요법으로 활성화되기를 기대한다.

• Communications for Statistical Applications and Methods
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• 제18권5호
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• pp.581-594
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• 2011

제 1상 임상시험 계획에서 신약제의 최대허용용량을 추정하기 위해 전통적 방법인 표준 3+3계획과 모형중심의 베이지안 방법을 적용시킨 연속재평가방법이 주로 사용되고 있다. 본 논문에서는 치료불응 또는 재발된 백혈병이나 골수형성 이상증후군 환자를 대상으로 시행한 제 1상 임상시험의 연구계획을 개관하였다. 단순한 표준 3+3계획으로 환자확보 기간이 길어져 연구를 완성하지 못하고 때 이르게 중단할 수밖에 없는 실정에 반하여, 최근에 제시된 표준 3+1+1계획과 Rolling-6 계획은 연구기간을 크게 단축시킬 수 있다. 제1상 임상시험의 용량수준 선택과정에서 너무 보수적인 연구자의 태도는 최대허용용량의 정확한 추정을 불가능하게 한다. 새로운 환자에게 투여할 용량수준을 결정할 시점에서 용량제한 독성반응이 아직 나타나지 않은 환자의 관측시간 및 늦게 나타나는 환자의 독성반응 시간을 모두 감안한 연속재평가방법인 TITE-CRM계획이 유용하며, 이러한 CRM계획으로 진행되는 임상시험 시행 중 모의실험으로 각 용량수준에서 용량제한 독성반응율이 과대 또는 과소 추정되는지를 파악할 수 있음이 장점이다. 백혈병환자 대상의 임상연구에서 채택되는 제 1상 임상시험의 여러 연구계획의 장, 단점을 제시한다.

• 한국양식학회지
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• 제21권3호
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• pp.176-180
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• 2008

본 연구는 인위적으로 배란시킨 뱀장어 Anguilla japonica 배란란의 과숙특징을 생화학적으로 밝히고, 과숙을 방지하기 위한 하나의 방법을 제시하였다. 사용된 뱀장어 성숙란의 수정률과 부화율, 부화 후 3, 10일 후 생존율과의 관계는 Y=0.7954X+32.448($R^2=0.8176$, P=6.35E-7), Y=1.0241X-26.401($R^2=0.8121$, P=5.95E-27) 및 Y=0.9314X-24.814($R^2=0.7619$, P=7.33E-14)였다. DNA 함량은 부화율의 감소와 함께 20% 이하의 부화율을 보이는 배란란에서 유의적으로 가장 낮은 0.653 pg/ug protein을 보였다(P<0.05). 그리고 이들의 비는 부화율이 20% 이하의 난에서 1.058로 유의적으로 가장 높은 비를 보였다(P<0.05). 또한 부화율에 따른 total alkaline protease와 ACPase 활성은 모든 부화율 범위에서 유의적인 차이를 보이지 않았다(P>0.05). 단백질 함량은 부화율 20% 이하 배란란에서 유의적으로 가장 높은 186.16 ug/mg eggs의 함량을 보였다(P<0.05). 따라서 뱀장어의 과숙란은 지속적인 단백질의 공급으로 정상란의 과숙화를 촉진하여 부화율이 저하된다. 결국 세포는 과숙으로 인해서 죽었기 때문에, 간에서 생성된 난황단백질의 공급을 차단하거나 공급속도를 늦추어서 복강 내 배란 후 과숙을 방지해야 할 것으로 판단된다.

• Asian-Australasian Journal of Animal Sciences
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• 제12권5호
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• pp.742-746
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• 1999

The potential of Leucaena leucocephala and Prosopis cineraria leaves as nitrogen supplements ($16g/kg\;W^{0.75}/d$) to improve the utilization of a basal diet of rice straw by goats was assessed in a feeding trial. Rice straw supplementation with forage oats (Avena sativa) was fed as a control diet. DMI, $g/kgW^{0.75}$ of rice straw by goats receiving Leucaena was significantly (p<0.05) higher followed by Prosopis and oat fodder. The supplementation of Leucaena improved the digestibility coefficient of DM, OM, CP, NDF and ADF nutrient density. Goats on Prosopis or oat fodder supplemented straw responded similarly in terms of nutrient utilization. The intake ($g/kgW^{0.75}$) of DCP, TDN and nitrogen balance of goats were significantly higher (p<0.05) when Leucaena was fed. It is suggested that the Leucaena may be a useful N-supplement in areas where livestock are fed poor quality crop residues.

• 제어로봇시스템학회논문지
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• 제22권2호
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• pp.133-138
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• 2016

This paper describes the track initiation and target-tracking filter for ship tracking in a marine environment by using Light Detection And Ranging (LiDAR). LiDAR with three-dimensional scanning capability is more useful for target tracking in the short to medium range compared to RADAR. LiDAR has rotating multi-beams that return point clouds reflected from targets. Through preprocessing the cluster of the point cloud, the center point can be obtained from the cloud. Target tracking is carried out by using the center points of targets. The track of the target is initiated by investigating the normalized distance between the center points and connecting the points. The regular track obtained from the track initiation can be maintained by the target-tracking filter, which is commonly used in radar target tracking. The target-tracking filter is constructed to track a maneuvering target in a cluttered environment. The target-tracking algorithm including track initiation is experimentally evaluated in a sea-trial test with several boats.

• 대한조선학회논문집
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• 제55권4호
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• pp.361-369
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• 2018

The ship surveyor makes a scheme of reasonable ship operation by examining whether the ship has been properly constructed in accordance with the rule of classification societies and international conventions or whether the facilities of the ship in operation meet the standard stipulated by law. Even though the ship surveyors of classification society generally consist of people who have the skill of design or operation of a ship, it takes a long time to train a surveyor to the maturity level. This paper describes the development of survey simulator based on virtual ship environment that enables the surveyor minimize trial and errors to survey the ships. By using VR(Virtual Reality) based survey simulator, surveyors possibly achieve improvement of competence in survey quality by means of safe and immersive training environment. In order to improve the usability and utility of the VR simulator, the ship 3D model has been generated using 3D CAD model for design and production in shipyard. Through this, we suggested the possibility of consistent use of 3D model as the digital twin of a ship.

• Journal of Advanced Marine Engineering and Technology
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• 제35권3호
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• pp.301-308
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• 2011

International Maritime Organization (IMO) proposed the Energy Efficiency Operation Indicator (EEOI) in 2005 and the Energy Efficiency Design Index (EEDI) in 2008 so as to address emission concern and regulation. Likewise, Ship Energy Efficiency Management Plan (SEEMP) and Greenhouse Gas (GHG) monitoring and management are also becoming an issue lately. This paper introduces the energy efficiency design index (operation indicator) monitoring system (EDiMS) software can continuously monitor $CO_2$, $NO_x$, $SO_x$, and PM values emitted from ship. The accurate inventory of ships GHG can be obtained from base of emission result during the engine shop test trial and the actual monitoring of shaft power and ship speed. In addition, the ability to store all exhaust emission and engine operation data can be applied as the useful tool of the inventory work of air pollution and ship energy management plan for the mitigation or reduction of ship emissions.

• 한국해양공학회지
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• 제21권2호
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• pp.60-66
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• 2007

The first Korean cold room facility for ice mechanics experiments was assembled in 2004. Since then, the $4m{\times}6m$ cold room facility has been used, extensively under various environmental and loading conditions. After reviewing published references on cold room testing methods and also by trial and error, the standard procedures for testing and preparing laboratory ice material were established for the measurement of basic ice properties. In this paper, laboratory experimental techniques with the cold room facility and standard procedures established for ice material properties are introduced. Test specimens include laboratory-grown fresh water ice and frozen soils. Tests are carried out for unconfined compressive strength. Preparation and dimension of the specimen are the most important issues arising in cold room tests. The details of specimen preparation, testing procedure and strength test results are also discussed.

• 한국수산과학회지
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• 제46권5호
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• pp.540-545
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• 2013

This study investigated the effect of diets supplemented with different levels (0, 1, 3, and 5 %) of turmeric Curcuma longa L. powder (TP) on the body composition of black rockfish Sebastes schlegeli. Fish weighing $10.05{\pm}0.44$ g were fed to apparent satiation twice daily for 8 weeks. Adding TP decreased crude lipid levels and increased crude protein and ash levels. Abundant fatty acids in the TP-added group were C16:0, C18:1 n-9 (cis), and C22:6 n-3. The major amino acids in samples were glutamic acid, aspartic acid, glycine, leucine, alanine, lysine, and arginine.

• 혜화의학회지
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• 제19권2호
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• pp.165-171
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• 2011

Objectives: This study analyzed the contents of the research papers of Maekmundong-tang (MMDT). This study was conducted to help development of new clinical application and clinical studies for treating COPD with Oriental medicine. Materials and Methods: We inspected 26 theses and scrutinized their classification, objective diseases, study design, participants, methodological quality of clinical trial. Results: The following results were obtained in this study. 1. The studies of MMDT started in 1989 and have continuously increased, but it decreased recently. 2. The studies were mainly focused on experimental models rather than clinical studies. The topics of studies were mainly relaxation of airway contraction and anti-asthmatic effect. 3. MMDT was showed to have effects on chronic cough and asthma in these papers. Conclusion: MMDT is being used in respiratory disease. However, mechanism study should be conducted at experimental study and more clinical studies on the efficacy of MMDT for chronic respiratory disease are needed.