• 대한한방내과학회지
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• 제42권6호
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• pp.1319-1330
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• 2021

A 56-year-old male patient with a sudden onset of tremor and involuntary movement of right upper and lower extremities, head, and voice was diagnosed as having a drug-induced tremor, with valproic acid being the culprit drug. The patient had undergone admission treatment at an internal Korean medicine department with herbal medicine according to constitutional diagnosis, acupuncture, moxibustion, cupping, and rehabilitation. The change in the severity of tremor was assessed with the Fahn Tolosa Marine scale. After discharge, the patient took herbal medicine for two more months. After 20 days of admission and 2 months of treatment with herbal medicine, the patient's tremor improved. In this case, the patient with valproic acid-induced tremor showed improvement in symptoms after 20 days of hospitalization and further reduction of tremor and improvement of quality of life were confirmed through follow-up for 2 months.

• 동의신경정신과학회지
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• 제21권3호
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• pp.95-103
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• 2010

가족 간의 갈등으로 인해 발생한 두부진전이 4-5년간 지속된 환자에게 한약물과 한방정신요법을 시행하여 증상의 유발과 악화인자에 대한 통찰을 하고 조절할 수 있는 통제력을 가지게하여 증상을 완화되었고, 수개월이 지난 지금까지 호전상태가 지속되는 것을 경험하였다. 심인성 운동장애는 전체 운동장애 중 2-3% 정도로 드물게 일어나며, 진전이 가장 흔한 형태이기는 하나 상하지에 많이 발생하고, 두부에만 국한적으로 일어나는 경우는 드물다. 이에 상기 증례는 다른 신경학적 증상을 동반하지 않고 두부에만 국한적으로 진전이 발생한 환자에게 한의학적 치료를 하여 유효한 결과를 얻었기에 보고하는 바이다.

• Journal of Korean Neurosurgical Society
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• 제37권2호
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• pp.105-111
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• 2005

Objective: Tremor, either essential tremor or Parkinsonian tremor, has been effectively and safely treated by lesioning the ventral intermediate(Vim) nucleus of the thalamus with or without mircroelectrode recording. The authors evaluate the treatment outcome of sixteen tremor patients who had been treated with thalamotomy without microelectrode. Methods: Between September, 2001, and December, 2003, sixteen tremor patients were treated with thalamotomy without microelectrode recording. Twelve patients suffered from Parkinsonian tremor and four patients were essential tremor patients. The male to female ratio was 1.6 to 1 with median age of 59.6 years (range; 39-74 years). Under local anesthesia, a 3mm hole was made using a hand-held twist drill, and the dura mater was penetrated with a 1.2mm sharp drill beat. Radiofrequency(RF) electrode was placed in the Vim nucleus of thalamus. With intraoperative macrostimulation, RF lesion was made. Postoperative CT scan and/or MR imaging was performed to confirm the localization of the target lesioned. Preoperative and postoperative tremor was evaluated with simple tremor severity scale and the development of complications related with the procedure was closely reviewed at the immediate postoperative period and the last follow-up. Results: It produces immediate relief in up to 98.4% of the patients. There were no development of complications related with procedure, all patients discharged one or two days after surgery. Conclusion: Vim thalamotomy without microelectrode recording is a safe and effective procedure to control the tremor with minimal morbidity. Intraoperative macroelectrode stimulation safely localizes the Vim nucleus target of the thalamus for the treatment of patients with tremor.

• 대한의용생체공학회:의공학회지
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• 제35권4호
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• pp.81-86
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• 2014

One of the methods for Parkinson's disease(PD) tremor evaluation is the Clinical Tremor Rating Scale(CTRS). However, the method has some limitations that clinician ratings can vary because the scores are subjectively rated. In addition, most researches usually collected data measured on the more affected arm. In this study, we developed a portable wearable system(SNUMAP system) for measuring PD tremor. The SNUMAP system captures 3-dimensional motion using tri-accelerometer and tri-gyroscope on finger and wrist. 40 PD patients participated in resting tremor and postural tremor tasks, while wearing the system on both hands simultaneously. Estimated tremor scores from Leave-One-Out Cross Validation for regression were highly correlated to the average clinician CTRS scores for rest tremor($r^2$ = 0.87, RMSE = 0.48) and postural tremor($r^2$ = 0.82, RMSE = 0.48). Therefore, the quantitative assessment model can improve treatment of PD patients.

• 동의신경정신과학회지
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• 제23권3호
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• pp.129-142
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• 2012

본 증례에서는 상기한 바와 같이 화병을 주로 한 심리상태 변화에 의해 악화된 진전증을 주소로 본원 한방신경정신과에 입원한 환자에게 한약치료와 침치료, 한방정신치료를 병행한 결과 제반증상 및 심리 상태 상 양호한 효과를 보여 이에 보고하는 바이다. 1. 18일간의 한약치료, 침치료, 정신요법 및 부항, 뜸의 기타치료를 통해 전신의 본태성진전증과 화병의 증세의 동반 호전을 경험하였다. 2. 화병 및 신체 상태를 심신불교(心腎不交)로 변증하고 황련아교탕(黃連阿膠湯) 처방을 기본 방제로서 증세변화에 따라 가감투여했으며, 정서적 안정과 기타 신체증상과 함께 진전증이 호전됨을 확인하였다.

• 대한의용생체공학회:의공학회지
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• 제41권6호
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• pp.247-255
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• 2020

Accurate diagnosis of movement disorders is important for providing right patient care at right time. In general, assessment of motor impairment relies on clinical ratings conducted by experienced clinicians. However, this may introduce subjective opinions into scoring the severity of motor impairment. Digital devices such as table PC and smart band with accelerometer can be used for more accurate and objective assessment and possibly helpful for clinicians to make right decision of patient's states. In this study, we introduce quantification algorithms of motor impairment which uses the digital data acquired during four clinical motor tests (Line drawing, Spiral drawing, Nose to finger and Hand flip tests). The step by step procedure of quantifying metrics (Tremor Frequency, Tremor Magnitude, Error Distance, Time, Velocity, Count and Period) are provided with flowchart. The effectiveness of the proposed algorithm is presented with the result from simulated data (normal, normal with tremor and slowness, poor with tremor, poor with tremor and slowness).

• 생물정신의학
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• 제8권1호
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• pp.167-174
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• 2001

A 54-year old male patient who was suffering from bipolar I disorder for 19 years and was admitted to the National Bugok Mental Hospital due to a depressive episode, was referred to the Kosin University Gospel Hospital. On arrival at the emergency room, he had confused mentality with disorientation, memory impairment, hypomania, marked anxiety and hyperirritability. The change of neuromuscular activity such as ataxia, gait disturbance, tremor, shivering, myoclonus and epileptic seizures was also shown. In addition, the symptoms and signs of autonomic instability including diaphoresis, tachycardia, hypotension, fever and facial flushing were noticed. The above symptoms developed after the administration of sertraline successive to the discontinuation of fluoxetine without any washout period. The degree of severity seemed to be severe because he had epileptic seizures, fever and hypotension. He was recovered from the severe serotonin syndrome by the supportive symptomatic treatment with sodium valproate, clonazepam, lorazepam and cyproheptadine after cessation of the selective serotonin reuptake inhibitors during hospitalization. Therefore, this rare case of severe serotonin syndrome was reported and related literatures were also reviewed.

• 대한물리치료과학회지
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• 제6권3호
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• pp.117-123
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• 1999

The prognosis and result of treatment are influenced by associated cerebral handicaps. 38 cerebral palsied children in rehabilitation center were analized and neuromotor type severity associated defects, and their correlation were studied. The results were follows: 1. neuromotor type distribution was 65.78% of spasticity, 21.05% of athetoid, 2.63% of Ataxia, Tremor, and Rigidity, 5.26% of mixed type. 2. Mean values of I.Q, S.Q and M.Q were 84.3, 63.0 and 26.6 respectively, and percentages of strabismus, speech disturbance, shoulder abnormality, spine abnormality and hip abnormality were 26.3%, 81.5%, 5.2%, 52.6% and 15.9% respectively. 3. Significant differences were noted between each group of mild, moderate, and severe in S. Q, M. Q, and spine abnormality and between moderate and severe group in speech disturbance.