• Title/Summary/Keyword: Treatment selection

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Effects of Natural Selection, Mutagenesis, and Protoplast Formation and Cell Wall Regeneration on the Production of Aminoglycoside Antibiotics

  • Goo, Yang-Mo;Lim, Hyon-Joo;Lim, Seok-Ran;Kim, Kong-Hwan;Lim, Bun-Sam;Lee, Sae-Bae
    • Archives of Pharmacal Research
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    • v.12 no.4
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    • pp.249-253
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    • 1989
  • High producers or blocked mutants of aminoglycoside antibiotic-producing Streptomyces spp. were selected by application of an agar plug method and by culturing individual colonies in broth. The productivities of aminoglycoside antibiotic producing organisms were increased by selection of a high producer from colonies obtained by spreading spores of wild strain, or survived from treatment of a mutagen or from the colonies regenerated from protoplast-formation and cell-wall regenerations. Some mutagen treated colonies lost the ability to produce antibiotics (5-8%). Some A-factor negative and deostreptamine or streptidine negative mutants were obtained by N-methyl-N'-nitro-N-nitrosomethylguanidine (MNNG) treatment. Many of the survivors from the MNNG treatment lost the ability to produce antibiotics. Major colonies produced less amount of antibiotics ; only few survived colonies produced more antibiotics than the parent. Resistance of Streptomyces spp. against the antibiotics produced by itself was also markedly affected by mutagen treatment.

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Diagnosis and treatment planning for removable partial denture: diagnostic cast analysis and abutment teeth selection (가철성 국소의치의 진단 및 치료계획: 진단모형 분석과 지대치 선정)

  • Son, Mee-Kyoung
    • Journal of Dental Rehabilitation and Applied Science
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    • v.30 no.1
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    • pp.45-52
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    • 2014
  • Diagnosis and treatment planning is initial step to fabricate removable partial denture, and one of most important factor influencing the prognosis. Partial edentulous patients have various condition of remaining teeth and oral mucosa. Therefore, for the proper diagnosis and treatment planning for each patient, getting many informations from patients during initial examination and fabricating accurate diagnostic cast are required. Especially, because the use of various diagnostic tools and surveying of diagnostic cast will be a guide for the abutment teeth selection, oral preparation and design of partial denture, dentist should understand and be able to apply this procedure during diagnosis.

Effect of Silvicultural Treatments on Carbon Storage of Northern Hardwood Forests

  • Park, Byung Bae;Kim, Young Kwan;Lee, Sang Ick
    • Journal of Korean Society of Forest Science
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    • v.96 no.2
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    • pp.208-213
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    • 2007
  • This study is designed to provide forest managers and landowners with tools to estimate the effect of forest management on carbon storage, investigating living tree biomass, detritus, and harvested wood products as variables. Thinning, selection cutting, and uncutting were applied to the three different forest types in New York, USA. Carbon storage of the original stands was 90, 56, and $101Mg\;ha^{-1}$ at the Allegheny hardwood forest, Northern hardwood forest, and Oak - black cherry forest, respectively. Among treatments, uncutting generally stored the greatest amount carbon. However, the rate of carbon storage was the smallest at the uncut treatment in all the sites. The 50% thinning, 50% selection, and 50% thinning treatments were the highest rate of carbon storage at the Allegheny hardwood forest, Northern hardwood forest, and Oak - cherry forest, respectively. In this study, only short term was applied to simulate carbon sequestration after silvicultural treatment. So, more research is needed to determine whether any silvicultural treatment can store significantly more carbon than no treatment over the long term.

Patient-Controlled Sedation for Dental Treatment (치과치료를 위한 진정자가조절법)

  • Seo, Kwang-Suk
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.13 no.3
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    • pp.81-87
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    • 2013
  • This article discusses the issues of benefit and possibility of application of patient-controlled sedation (PCS) for the dental treatment. The purpose of administering PCS for patients is to diminish anxiety and to provide cooperative and effective dental treatment. But there are a lot of barriers to application of PCS such as knowledge about pharmacokinetics of sedatives, expensive high speed and patient-controllable syringe pump, and well educated sedationist. And there could be risk of deep sedation, airway obstruction and hypoxic brain damages, etc. In order to decrease incidence of complication, appropriate drug selection, selection of right bolus dose, lock-out time is much important.

Roller Design of IRB Seismic Isolation Device Using Test Evaluation : Part II. Heat Treatment of Material (시험평가법을 이용한 IRB 면진장치 롤러 설계 : Part 2. 소재 열처리)

  • Park, Young-Gee;Ha, Sung Hoon;Seong, Min-Sang;Jeon, Junchul;Choi, Seung-Bok
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.23 no.4
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    • pp.332-337
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    • 2013
  • This paper presents a subsequent research work on the roller design of IRB(isolation roller bearing) seismic isolation device presented in Part 1 by focusing on heat treatment. The hardness and friction factor are very important factors of material and after-treatment process selection. Normally, roller bearing consists of roller and retainer. The roller gets high pressure constantly, while the retainer gets tensile and compressive stress. Therefore, sensitive material selection and heat treatment of each part is quite important. In this experimental evaluation, carbon steel, chrome special steel and others are employed and their characteristics after heat treatment are identified. Each material is prepared by refining high frequency heat treatment. The friction factor and static load capacity of manufactured material are experimentally identified and destructive test of material is processed. Optimal material and heat treatment conditions for IRB roller bearing are determined based on experiment results.

The Study on Selection Factors of Ophthalmic Medical Institute and Habits of Information Searching (안과 의료기관 선택요인 및 정보탐색 행태에 관한 연구)

  • Lee, Hye-Jin;Lee, Jung-Woo;Hong, Sang-Jin
    • The Korean Journal of Health Service Management
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    • v.3 no.1
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    • pp.47-58
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    • 2009
  • This study is to grasp selection factors and habits of information searching of customers of ophthalmic service and to verify the differences in them and to investigate how they affect in selecting medical institute by demographic sociological characters, selection factors by classification and habits of information searching, how many times they used and the type of medical treatment. The result of analysis of importance of selection factors of medical institute, it showed that doctors' career were evaluated high by classification and it showed in order of university hospital, hospital, clinic in facilities and equipment and in order of university hospital, clinic, hospital in distance transportation Analysis of importance of selection factors by sex distinction, it showed that doctors' career were high for both male and female and according to the result of analysis of selection factors by an age, doctors' career variable was measured high and it showed in order of facilities, equipment, distance and convenient transportation. The result of analysis by the form of medical treatment, doctors' career were measured high in all diseases. Facilities and equipment were measured high in case of a corrective operation of eyesight and distance transportation variable showed high in simple eye diseases. According to the result of analysis of habits of searching information by utility frequency, one's own experience in the past(direct visits) was the highest over all and it showed in order of introduction of other ophthalmic department in case of people who go to the institutes many times.

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A Case Study for Site Selection of the Waste Treatment Facilities (폐기물처리시설 입지선정에 따른 사례연구)

  • 이해승
    • Journal of environmental and Sanitary engineering
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    • v.19 no.1
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    • pp.24-36
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    • 2004
  • This study is to investigate the present condition of waste disposal establishment and to analysis problems which could be produced at location selection formalities of waste disposal establishment. It proposed building methods of waste disposal establishment to lead spontaneous participation of local resident according to case analysis of waste disposal establishment. There are research results; i) Opposition of inhabitants was the majority of reason at the business abandonment or delay of waste disposal establishment. Therefore agreement formation course with local inhabitants is most important position. ii) Many estimate have been needed for waste disposal establishment, but support estimate of government was 30-50% that is really low compare with other environmental establishment. So that it need to increase of government estimate. iii) Location collection is carried out based on law and final collected location must be executed without delay of relation business as soon as possible. iv) Standard of location collection has to divide into small, middle and large size and to apply with same rule according to divided location. v) It must be change public subscription before and location selection after and maintain continuance of information offer to local inhabitants and offered information. vi) after building of waste disposal establishment for solving distrust of waste disposal establishment. It must be planed and carried on useful support countermeasure to local inhabitants in actuality.

Difference in Length of Stay and Treatment Outcome of Pulmonary Tuberculosis Inpatients between Health Insurance Types (의료보장유형에 따른 폐결핵 입원환자의 재원기간과 치료결과 차이분석)

  • Kim, Sang Mi;Lee, Hyun Sook;Hwang, Seul ki
    • Korea Journal of Hospital Management
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    • v.21 no.4
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    • pp.45-54
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    • 2016
  • The purpose of this study is to identify patient and hospital characteristics with pulmonary tuberculosis and to analyze factors which were influencing length of stay and treatment. The Korean National Hospital Discharge In-depth Injury Survey database from 2006 to 2012 was used for analysis. Study subjects were 4,704 patients and analyzed by using frequency, chi-square and logistic regression through using STATA 12.0. To avoid selection bias, we used propensity score matching. Analysis results show that the length of stay and treatment of pulmonary tuberculosis was different between insurance types. Patients characteristic(female, comorbidity, admission by outpatient department, medical insurance type) and hospital characteristic(500-999 beds, over 1000 beds) significantly influence length of stay. Admission by outpatient department and over 1000 beds are significantly influence treatment. Based on these findings, it is necessary to clarify between length of stay and treatment outcome by medical aids beneficiaries and audit hospitals follow discharge guidelines in pulmonary tuberculosis patients.

Practical Approach for Pavement Treatment Decisions for Local Agencies

  • Abdelaty, Ahmed;Jeong, H. David;Smadi, Omar
    • Journal of Construction Engineering and Project Management
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    • v.7 no.1
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    • pp.30-36
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    • 2017
  • Most local agencies such as counties and small cities continuously express difficulties in making technically and financially defensible decisions on their pavement infrastructure maintenance and rehabilitation. Unlike pavement systems managed by state highway agencies, the total lane-miles of many local pavements are significantly short and they are managed by a limited number of staff who typically have multiple responsibilities. Most local agencies also do not have historical pavement performance data and the lack of a systematic decision making framework exacerbates the problem. A structured framework and an easily accessible decision support tool that reflects their local requirements, practices and operational conditions would greatly assist them in making consistent and defensible decisions. This study fills this gap by developing a systematic pavement treatment selection framework and a spreadsheet based tool for local agencies. It is expected that the proposed framework will significantly help local agencies to improve their pavement asset management practices at the project level.

Surgical treatment of velopharyngeal insufficiency

  • Nam, Seung Min
    • Archives of Craniofacial Surgery
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    • v.19 no.3
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    • pp.163-167
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    • 2018
  • Velopharyngeal insufficiency (VPI) is a common complication after primary palatoplasty. Although the several surgical treatments of VPI have been introduced, there is no consensus guide to select the optimal surgical treatment for VPI patients. The selection of surgical treatment for VPI depends on a multimodal patient evaluation, such as perceptual speech evaluation, nasometery and nasoendoscopy. We can provide more adequate treatment for VPI through the deeper understanding of anatomy and physiology in VPI.