• 제목/요약/키워드: Treatment efficacy

검색결과 4,292건 처리시간 0.033초

비알콜성 지방간 환자에 대한 베르베린 투여 치료의 임상적 효능 연구: 체계적 문헌 고찰과 메타분석 (Clinical Efficacy of Coptidis Rhizoma for Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis)

  • 박송원;김민지;임성우
    • 한방비만학회지
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    • 제22권2호
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    • pp.158-166
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    • 2022
  • Objectives: The purpose of this meta-analysis was to evaluate the effects of berberine on non-alcoholic fatty liver disease (NAFLD) through a systematic review and meta-analysis. Methods: We searched seven electronic databases for studies through October 2022. All randomized controlled trials (RTCs) of berberine were included. Data extraction and risk of bias assessments were performed by two independent reviewers. The RevMan 5.4.1 program was used for meta-analysis. Results: A total of 279 relevant studies were identified, and 6 eligible RCTs were included to study the efficacy berberine on NAFLD. The six selected trials are studies on the effect between berberine and conventional treatment combined treatment versus conventional treatment. Liver function tests, blood lipid levels, and blood glucose levels were assessed. Combination treatment with berberine, ursodeoxycholate acid, metformin, and monascus purpureus showed statistically significant improvements in liver function levels, blood lipid levels, and blood glucose levels compared to conventional treatment alone. However, there was no significant efficacy of berberine combination dietary, exercise than control group on NAFLD. The meta-analysis results of examining 4 RCTs comparing the therapeutic efficacy of berberine showed statistically significant improvement in the liver function test, blood lipids levels, blood glucose levels. Conclusions: This study suggests that berberine has positive efficacy on blood lipids, blood glucose liver function, fatty liver condition of NAFLD. However, the level of evidence is low because of small effect size,so further investigation is needed.

다문화가족 방문교육지도사의 다문화 효능감과 직무만족도에 관한 연구 (A Study on Multicultural Family Visiting Instructors' Multicultural Efficacy and Job Satisfaction)

  • 채진영;김헤라;강복정;황혜신;권기남
    • 가정과삶의질연구
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    • 제32권5호
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    • pp.1-13
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    • 2014
  • This study examined the multicultural efficacy and job satisfaction of multicultural family visiting instructors. The subjects were 750 visiting instructors from 140 multicultural family support centers in Seoul, 6 metropolitan cities, 9 provinces, and other cities and counties. Data were analyzed through frequency, percentages, Pearson's correlations, One-way ANOVA, Scheff$\acute{e}$ post-hoc test, independent t-test, and stepwise multi-regression using PASW 18.0. The findings are as follows. First, there were statistically significant differences in all subscales of multicultural efficacy according to the teaching experiences of the multicultural family visiting instructors. On the other hand, there was a statistically significant difference only in trust in the relationships with multicultural families according to the teaching experiences of the multicultural family visiting instructors. Meanwhile, the independent t-test showed that there was a significant difference only in satisfaction regarding treatment and salary according to the assigned work. Second, the stepwise multi-regression models revealed that three subscales (job performance, trust in the relationships with the multicultural families, job aptitude) of job satisfaction were influenced by multicultural efficacy according to both the teaching experiences and assigned work, but this was no the case for satisfaction about treatment and salary. Regardles of teaching experience or assigned work, teaching efficacy in multicultural efficacy affected all subscales of job satisfaction except for satisfaction about treatment and salary. The implications for future studies are also discussed.

CNKI로 검색한 소아 수두의 한약 내복 치료에 대한 임상연구 동향 - 2000년대 이후 RCT 연구를 중심으로- (Review of Clinical Studies of Oral Herbal Medicine Treatment for Pediatric Chickenpox using CNKI Database - Focused on Chinese Randomized Controlled Trials after 2000s -)

  • 최정윤;김장현;민상연
    • 대한한방소아과학회지
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    • 제34권3호
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    • pp.18-36
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    • 2020
  • Objectives The purpose of this study is to analyze Chinese randomized controlled trials (RCTs), and to evaluate the effectiveness and safety of the oral herbal medicine treatment for pediatric chickenpox. Methods We searched RCTs after 2000s from the China National Knowledge Infrastructure (CNKI). Afterwards, the year of publication, demographic information, duration of chickenpox, intervention, treatment duration, outcome measure, results and adverse events were investigated and analyzed for this study. Results 21 RCTs out of 219 studies were collected and analyzed. Although each composition of the herbal medicine was different, they have common ingredients such as 清熱解毒, 散結消腫, 疏散風熱, 涼血解毒, 解表散風 in order to make efficacy of 清熱解毒, 散結消腫, 疏散風熱, 涼血解毒, 解表散風. The oral herbal medicine showed better efficacy and safety to improve clinical symptoms such as total efficacy, cure rate, antipyretic time, antipruritic time, scab time, anti-rash time, hospitalization period and herpes recovery time compared to the western medicine treatment. Conclusions These results show that the oral herbal medicine treatment on chickenpox in children may be more effective in reducing of clinical symptoms compared to the western medicine treatment.

Video프로그램을 통한 환자교육이 결핵환자 치료이행행위에 미치는 영향 (The Effect of Behavior Modification on Enhancing Patient Adherence to Tuberculosis Treatment Regimens)

  • 정은리
    • 대한간호학회지
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    • 제26권3호
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    • pp.697-708
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    • 1996
  • Most efforts to improve tuberculosis treatment adherence target the patient and his or her behavior. This study examined the effects of behavioral modification training for these patients. Based on Bandura's behavioral principles of modeling, intervention strategies using a video program were devised to elicit specific patient target behaviors considered to improve patients' adherence to tuberculosis treatment regimens. A random assignment, two-group(experimental group and control group) research design including 81 subjects was used. The main outcomes measured were pill taking measured with the Medication Event Monitoring System(MEMS) Medication Cap, patients' self-efficacy, and their knowledge of tuberculosis. The findings are as follows : 1) There was a significant difference between the experimental group and the control group in patients' feelings of self-efficacy. That is, the patients who received the behavior modification program showed greater feeling of self-efficacy to initiate and change their behavior for the tuberculosis treatment regimen than the patients who did not receive the program(t=3.51, p=0.01). 2) There was a significant difference between the experimental group and the control group in patients' knowledge of tuberculosis. That is, the patients who received the behavior modification program showed higher level of knowledge of tuberculosis than the patients who did not receive the program(t=2.15, p=0.03) 3) There was a significant difference between the experimental group and the control group in patients' adherence to tuberculosis treatment regimens. That is, the patients who received the behavior modification program showed greater adherence to the treatment regimens than the patients who did not receive the program(t=5.11, p=0.00). The study findings provided useful insights into nursing practice, particularly in planning intervention strategies aimed at enhancing patients' adherence in tuberculosis that may also be relevant to other chronic diseases with patient adherence problems.

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상호또래교수에서의 반성적 저널쓰기 활동이 수학자기효능감에 미치는 영향 (Effects of reflective journal writing to mathematics self-efficacy in reciprocal peer tutoring)

  • 최계현;황우형
    • 한국수학교육학회지시리즈A:수학교육
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    • 제53권1호
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    • pp.1-24
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    • 2014
  • This study examines the effects of reflective journal writing on the mathematics self-efficacy in reciprocal peer tutoring. Participants were 38 high school students in Gyeonggi province who attended at a summer intensive mathematics course for 4 weeks. This study used a mixed method. SPSS 21.0 program was used to analyze the quantitative data, and the interviews, observational journals and reflective journals of 6 students were used to analyze qualitative data. According to the results, all the subcategories of mathematics self-efficacy, - mathematics problem-efficacy, mathematics success-efficacy, mathematics learning-efficacy, and mathematics subject-efficacy - improved except mathematics occupation-efficacy. In case of mathematics success-efficacy and mathematics problem-efficacy, students revealed the greatest improvement. In conclusion, reflective journal writing in reciprocal peer tutoring could be suggested as a treatment program to improve students' mathematics self-efficacy.

억간산가미방(抑肝散加味方) 투여(投與)와 구치료(灸治療)를 위주로 한 포륜진도(胞輪振跳) 치험2례(治驗2例) (Two cases of the treatement of hemifacial spasm improved by Ukgansangamibang(抑肝散加味方) and moxa-treatment)

  • 박민철;홍승욱
    • 한방안이비인후피부과학회지
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    • 제20권3호
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    • pp.236-242
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    • 2007
  • Objectives : This study was performed to report two cases of improved hemifacial spasm by herbal remedy and moxa-treatment. Methods : This study calendered the improvements of symptoms of two patients with hemifacial spasm who visited the author's clinic. Ukgansangamibang(抑肝散加味方) and moxa-treatment on chung-wan(CV12) were prescribed to the patients concerned due to their antipathy against acupuncture treatment. Results : Significant improvements were observered from both patients not only for hemifacial spasm but neuropsychosis-related symptoms Conclusion : The study shows remarkable results of the efficacy of herb remedy and moxa-treatment, for the treatment of hemifacial spasm , however the cases investigated in this study were only two(2). Therefore, more studies should be followed to support the efficacy of Oriental Medicine for the treatment of hemifacial spasm.

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병원코디네이터의 역할갈등 및 자기효능감이 직무만족에 미치는 영향에 관한 연구 (The Effects of Role Conflict and Self Efficacy on Job Satisfaction for Hospital Coordinators)

  • 김미;홍남희
    • 한국병원경영학회지
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    • 제14권3호
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    • pp.104-131
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    • 2009
  • This study analysed what effects conscious role conflict and conscious self-efficacy have on job satisfaction for hospital coordinators working in medical institutions. In order to study this issue, questionnaires were distributed to 154 hospital coordinators. The results from analysing the effects of role conflict and self-efficacy on job satisfaction are as follows: 1) Role conflict and job satisfaction are negatively correlated. The mean score for hospital coordinators' role conflict was 2.82, which was lower than average. Among subfactors for role conflict, personal role conflict had a significant effect on job satisfaction, while role ambiguity had no effect on job satisfaction. 2) The mean score for hospital coordinators' self-efficacy was 3.42, which was slightly higher than average. Other mean scores were as follows: job attitude 3.83, interpersonal skills 3.54, administrative knowledge 3.30, and medical treatment knowledge 3.02. Among subfactors for self-efficacy, job attitude and adminstrative knowledge had significant effects on job satisfaction, while interpersonal skills and medical treatment knowledge had no effect on job satisfaction (p < 0.01). In conclusion various hospital administration techniques, related job training and education needs to be given when introducing a hospital coordinator in order to strengthen the competitiveness of medical institutions. The hospital coordinators need to clearly understand their role so that they can settle into the system at the hospital and develop their job environment.

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Anti-Allergic Effect of Fermented Extracts of Medicinal Plants Andrographis paniculate, Salvia plebeia R. Br., Canavalia gladiate, Eleuthorococcus senticosus, Ulmus davidiana var. japonica, and Clerodendrum trichotomum Thunb. ex Murray

  • Mi Jeong, Choi;Yu Ri, Kim
    • 한국미생물·생명공학회지
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    • 제50권4호
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    • pp.512-521
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    • 2022
  • Since the main symptoms of COVID-19 involve the respiratory system, the infection rate of this disease is predicted to be higher in patients with other respiratory conditions such as allergic rhinitis. In such a situation, it will be meaningful to conduct research on an allergy treatment that has fewer side effects and can effectively reduce allergy symptoms. Here, we prepared experimental samples under various fermentation conditions with mixed extracts of six medicinal plants. To examine the anti-allergic efficacy of these samples, an egg albumin-induced allergic rhinitis animal model experiment, a serum histamine and IgE experiment, and a COX and LO inhibitory activity experiment were conducted. As a result of animal experiments, OVA+SP-4 showed superior efficacy compared to OVA+SP-1 in nasal rubbing and sneezing experiments and had anti-allergic efficacy similar to that of OVA-cetirizine. The serum histamine concentration of OVA+SP-4 was also 1.3 times higher than that of the OVA+cetirizine group, showing a high histamine reduction ability, and IgE showed the same trend. An analysis of COX inhibitory efficacy also confirmed that COX-1 and COX-2 inhibitory efficacy is high, and the longer the fermentation time, the higher the antiallergic efficacy. The composition proposed by this study is expected to have a significant effect on sustainable allergy prevention and treatment in the future by applying it to human patients.

Efficacy of Pharmacopuncture for Treating Children with Physical Disabilities in Uzbekistan

  • Zohidjon, Ismailov N.;Yu, Jun-Sang
    • 대한약침학회지
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    • 제16권2호
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    • pp.23-27
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    • 2013
  • Objective: This research was performed to investigate the efficacy of complex rehabilitation combined with pharmacopuncture treatment for the children with neuromotor system diseases. Methods: Fifty (50) patients aged from 5 to 15 yr old were compared. Twenty (20) patients received conventional treatments and complex rehabilitation as a control group, and fifty (50) patients received complex rehabilitation with pharmacopuncture. At their first visits, the patients had checkups and neurological scales, and after 10 days of pharmacopuncture treatments and 55 days of rehabilitation, they also took neurological scales. We studied the pre and post effects of the treatment group. Results: The number of patients with ankle joint disorder and contracture, knee joint contracture, steppage, horsey hoof, shoulder weakness and contracture, radio-carpal joint disorder and contracture, arm hypotrophia, arm atrophia, leg hypotrophia and total atrophia decreased after treatments. Conclusion: This study showed the efficacy of pharmacopuncture combined with complex rehabilitation for the treatment of neuromotor system diseases.

Does Aging Matter? The Efficacy of Carpal Tunnel Release in the Elderly

  • Fung, Bettina Wai Yan;Tang, Chris Yuk Kwan;Fung, Boris Kwok Keung
    • Archives of Plastic Surgery
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    • 제42권3호
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    • pp.278-281
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    • 2015
  • Open release remains the gold standard in the treatment of carpal tunnel syndrome in cases where conservative treatment fails. However, the efficacy of carpal tunnel release in the elderly has been debated in the literature throughout the years. This review aims to review the current evidence pertaining to the efficacy of carpal tunnel release in the elderly. Based on the current evidence, the outcome of carpal tunnel release is unpredictable in the elderly. Elderly patients are also less satisfied with the operation compared to younger patients. The authors recommend that these messages be conveyed to elderly patients before surgery. Moreover, open carpal tunnel release should be offered in the early stages of treatment whenever operative management is indicated.