• Journal of Life Science
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• v.22 no.4
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• pp.516-523
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• 2012

The purpose of this study was to investigate the effect of exercise and/or L-arginine on abdominal fat, IGF-1 on GH/IGF-1 axis, fibrinogen, and PAI-1 in aged and obese rats. Male Sprague-Dawley rats were treated with a D-galactose aging inducing agent (50 mg/kg) given intraperitoneally for 12 weeks. Thirty-two male Sprague-Dawley rats were treated and divided into four groups: aging-high fat diet group (AG+HF), AG+HF with L-arginine intake group (AG+LA), AG+HF with exercise group (AG+EX), and AG+EX with L-arginine intake group (AG+LA+EX). The experimental rats underwent treadmill training (60 min/day, 6 days/week at 0% gradient) for 12 weeks. L-arginine was given orally (150 mg/kg/day) for 12 weeks. After the experiment, blood was collected from the left ventricle and abdominal fat was extracted. The results showed that GH was significantly increased in AG+EX and AG+AL+EX. IGF-1 was significantly increased in both the AG+AL+EX and AG+EX group ($p$<0.05), while fibrinogen and PAI-1 were not significantly different among the groups. Abdominal fat was significantly decreased in the AG+LA, AG+EX, and AG+LA+EX groups ($p$<0.05) compared with the AG+HF group. In conclusion, this study suggests that exercise alone or L-arginine alone or a combination not only increases the GH and IGF-1 concentration, but also decreases the abdominal fat mass.

• Journal of Life Science
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• v.20 no.5
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• pp.805-810
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• 2010

The purpose of this study was to investigate the effect of Sea Tangle supplementation and exercise training on blood glucose and lipid profile in rats. Twenty seven, 4-week old male Sprague-Dawley rats were divided into the control group (C, n=9), sea tangle group (D, n=9) and sea tangle+exercise group (D+T, n=9). Exercise training was performed 5 days a week using a treadmill running program for 6 weeks (5 m/min, 0% grade, 30 min). There was no difference in blood glucose (C: $175.9{\pm}47.5$, D: $173.9{\pm}34.0$, D+T: $165.0{\pm}38.0\;mg/dl$) and triglyceride (C: $251.1{\pm}91.8$, D: $215.0{\pm}90.0$, D+T: $200.0{\pm}89.3\;mg/dl$) among the groups. Total cholesterol value of the D+T group ($81.8{\pm}11.2\;mg/dl$) was significantly lower than that of the C ($103.0{\pm}13.5\;mg/dl$) and D ($102.1{\pm}14.5\;mg/dl$) groups. High density lipoprotein cholesterol (HDL-C) was significantly high in the D+T ($40.9{\pm}9.7\;mg/dl$) group compared with the C ($32.6{\pm}3.8\;mg/dl$) group and D ($31.7{\pm}7.3\;mg/dl$) group. The value of low density lipoprotein cholesterol (LDL-C) for the D ($98.0{\pm}41.0\;mg/dl$) group was statistically lower than the C($114.5{\pm}41.8\;mg/dl$) group, and higher than the D+T ($91.2{\pm}41.7\;mg/dl$) group. In conclusion, sea tangle injection and exercise had a positive effect on blood lipid profiles.

• Journal of the Korean Society of Clothing and Textiles
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• v.44 no.4
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• pp.776-787
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• 2020

This study investigated physiological and subjective responses to different types of firefighter station uniforms made with various designs and materials. Six healthy males participated in this study that consisted of 20 min of rest, 30 min of treadmill exercise, and 30 min of recovery in a hot and humid environment (34℃ and 65%RH). The experimental clothing conditions were as follows. 1) a fitted T-shirt and trouser made of 100% polyester (FC-Uniform), and 2) flame retardant T-shirts made of acrylic and cotton as well as trousers with aramid and polyester, designed for overfitting (Control). There were no significant differences in the body temperature, and sweat rate between the two conditions; however, the heart rate with the FC-Uniform was significantly lower than Control (p=.025). The clothing microclimate temperature at the chest of the FC-Uniform was significantly lower than the Control (p=.037), and a difference of 1℃ was maintained until the recovery was complete. There were no significant differences in the subjective responses; however, participants experienced a humidity sensation faster with FC-Uniform in the recovery phase. The results indicate that changes in the design and material of firefighter station uniforms may have a positive influence on reducing the thermal stress of firefighters.

• The Journal of Korean Academy of Sensory Integration
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• v.2 no.1
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• pp.21-32
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• 2004

Objective : Effect of treadmill exercise on hippocampal neural cell proliferation under normal conditions and alcohol intoxication conditions has been recently studied; however, this effect under sensory stimulation application has not clarified yet. In the present study, the effect of compression stimulation application on hippocampal neural cell proliferation in the dentate gyrus in normal and alcohol intoxicated rats was investigated. Methods : Experimental design: comparative investigation on number of 5-Bromo-2'-deoxyuridine(BrdU)B-positive cells in dentate gyrus 5 days after commencement. Setting: animal laboratory. Participants: male Sprague-Dawley rats of 3weeks old in age weighing $80{\pm}10gm$. Intervention: animals were randomly assigned into 4 groups; control-rest group(n=8), control-compression group(n=8), alcohol intoxication-rest group(n=8) and alcohol intoxication-compression group(n=8). Animals of the alcohol intoxicated groups were injected intraperitoneally with alcohol(2g/kg) twice per day for 3 days. All animals were injected BrdU(50mg/kg) intraperitoneally, and rats compression stimulation application groups were compressed using sphygmomanometer cuff times per day, for 5 days following alcohol administration. Measures: mean number of BrdU-positive cells in dentate gyrus was observed via immunohistochemistry. Results : Compression stimulation application significantly increased the number of BrdU-positive cells in the dentate gyrus. Also, treatment with alcohol for 3 days inhibited cell proliferation, and compression stimulation application alleviated alcohol-induced inhibition of new cell formation. Conclusion : These results suggest the possibility that compression stimulation application may help in improvement following alcohol-induced brain damaged.

• Journal of the Korean Society of Clothing and Textiles
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• v.36 no.10
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• pp.1050-1057
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• 2012

This study helps develop a cool body armor that maintains a tight-fit configuration to the body surface and evaluates the performance of newly developed body armor in a wear test. Three types of body armor were used for evaluation. One was a tight fitting body armor that was constructed to improve the degree of fit and ease of movement for Korean soldier using 3D technology. Another was ventilating body armor with attached spacers on the shoulder to reduce the thermal stress on the soldier. The third was a prevailing body armor produced by a Korean body armor company. In order to evaluate the performance of the body armor, a human wear test, a thermal mannequin test, and computational fluid dynamics (CFD) were executed. Five subjects participated in the wear test. Subjective wear sensation, total amount of sweat and dynamic change of clothing microclimate were observed during and after exercise on a treadmill; subsequently, it was found that subjects rated tight fitting body armor and ventilating body armor lighter, drier, and easier to move than the conventional body armor (p<.05). Total amount of sweat was the least in the case of ventilating body armor. The thermal resistance and vapor resistance of the ventilating body armor were improved remarkably. In addition, the skin temperature of the ventilating body armor with spacers was lower than the tight fitting body armor by at least $1^{\circ}C$ in the CFD result. It is noted that thermal-wet comfort of the 3D body armor with ventilating feature is superior to the conventional body armor, especially when the ventilating channel is not closed due to a backpack.

• Toxicological Research
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• v.11 no.1
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• pp.161-168
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• 1995

It has been found that various stress challenges induce the myocardial antioxidant enzymes and produce an acquisition of the cellular resistance to the ischemic injury in animal hearts. Most of the stresses, however, seem to be guite dangerous to an animal's life. In the present study, therefore, we tried to search for safely applicable stress modalities which could lead to the induction of antioxidant enzymes and the production of myocardial tolerance to the ischemia-reperfusion injury. Male Sprague-Dawley rats (200-250 g) were exposed to various non-fatal stress conditions, i.e., hyperthermia (environmental temperature of $42^{\circ}C$ for 30 min, non-anesthetized animal), iramobilization (60 min), treadmill exercise (20 m/min, 30min), swimming (30 min), and hyperbaric oxyflenation (3 atm, 60 min), once a day for 5 days. The activities of myocardial antioxidant enzymes and the ischemia-reperfusion injury of isolated hearts were evaluated at 24 hr after the last application of the stresses. The activities of antioxidant enzymes, superoxide dismutase (SOD), catalase, glutathione peroxidase, glutathione reductase and glucose-6-phosphate dehydrogenase (G6PD), were assayed in the freshly excised ventricular tissues. The ischemia-reperfusion injury was produced by 20 min-global ischemia followed by 30 min-reperfusion using a Langendorff perfusion system. In swimming and hyperbaric oxygenation groups, the activities of SOD and G6PD increased significantly and in the hyperthermia group, the catalase activity was elevated by 63% compared to the control. The percentile recoveries of cardiac function at 30 min of the post-ischemic reperfusion were 55.4%, 73.4%, and 74.2% in swimming, the hyperbaric oxygenation and the hyperthermia groups, respectively. The values were significantly higher than that of the control (38.6%). In additions, left ventricular end-diastolic pressure and lactate dehydrogenase release were significantly reduced in the stress groups. The results suggest that the antioxidant enzymes in the heart could be induced by the apparently safe in vivo-stresses and this may be involved in the myocardial protection from the ischemia-reperfusion injury.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.5 no.2
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• pp.95-105
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• 2007

The purpose of this study is to define the effect of taping and icing on muscle fatigue at knee joint of ordinary adult. The 30 adults meeting research standard were chosen to be observed. The period of the research was 9 days and N-K table was used as equipment to measure position sense of knee joint. Heart rate monitor was also used to measure heart beat during both when in comfortable state and in exercises. For the method of this study, error in position sense of knee joint was measured right before fatigue occurs. Then volunteers were to be exercised for 10 minutes in treadmill aiming to raise the heart beat to 90%. If muscle fatigue occurs after the exercise, let the comparative group rest for 20 minutes while applying taping for group 1 and icing for group 2. For the icing, it was applied for 3 minutes followed by 1 minute rest. 5 sets of icing were applied on thighs and calf each, Then error of position sense of knee joint was measured same way it was done before muscle fatigue. As the result, there were similar differences among comparative group(p<.05), group 1 and group 2 before the muscle fatigue and after the muscle fatigue. There were similar differences in comparative group with muscle fatigue, group 1 and group 2 as the result of one-way ANOVA and with further examination, similar differences were only found in between comparative group and group 2(p<.05). With the result, we can see there wasn't clear effect of rest, icing or taping, however, group 2 with icing showed better condition compared to comparative group who have rested without any application.

• Anxiety and mood
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• v.2 no.1
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• pp.28-32
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• 2006

Objectives : Non-cardiac chest pain (NCCP) can be divided into gastroesophageal reflux disease (GERD) related NCCP and non-GERD related NCCP. Our study was designed to examine the differences in clinical characteristics and psychological mood states between the two clinical syndromes. Methods : After some cardiologic evaluations such as treadmill exercise, coronary angiography, and echocardiography, 27 patients with NCCP were enrolled in this study. They were divided into patients with GERD related NCCP (12 patients) and those with non-GERD related NCCP (15 patients) using the upper gastrointestinal endoscopy and the ambulatory 24 hour esophageal pH monitoring. Clinical characteristics such as typical reflux symptoms and psychological mood states were measured. Patients who showed scores more than 10 on the Beck Depression Inventory (BDI) or Beck Anxiety Inventory (BAI) were defined as depressed or anxious group. Anxiety sensitivity Index (ASI) was also measured in all patients. All parameters were compared between patients with GERD related NCCP and those with non-GERD related NCCP. Results : The two groups showed a difference in typical reflux symptoms. Patients with non-GERD related NCCP had higher scores on the BDI, BAI and ASI than those with GERD related NCCP. Among all NCCP patients, 14 patients (51.9%) were suggested to have possible depression or anxiety disorders. Conclusion : The non-GERD related NCCP was shown to be associated with psychological mood states such as anxiety and depression. Thus, we suggest that routine measurement of psychological mood states should be necessary in the evaluation and treatment of NCCP.

• The Research Journal of the Costume Culture
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• v.21 no.1
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• pp.81-92
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• 2013

Many women feel pain in their breasts while running due to an excessively large degree of breast movement. Therefore, most sports bras pursue a reduction in breast movement. The purpose of this study is to investigate the breast movement reduction effect of a selection of sports bra designs according to the intensity of the sport and the breast size of the wearer. The study measured differences in the vertical movement of the nipple with 4 types of sports bras and 3 exercise speeds(4km/h, 7km/h, and 10km/h). Subjects included women in their 20s with bra sizes of either B cup(n=3) or C cup(n=3). The results of the study are as follows. Breast movement differed according to running speed and breast size; breast movement significantly increased starting with jogging speed(7km/h), and the C-cup group had a larger degree of vertical movement than the B-cup group. A superior effect on breast movement during jogging(7km/h) and sprinting(10km/h) was observed differently by bra cup sizes. To C-cup group, encapsulation-style sports bra, which provides horizontal support across the upper breast and padding inside the shoulder strap and bra cup to ease impact was most effective and next effective style was the compression-style bra with a princess line to cover the breasts solidly. Most style sports bra were effective in the B-cup group. Besides aforementioned encapsulation-style sports bra, the compression-style bra with a band, which presses the breasts against the chest wall, reduced breast movement effectively.

• Journal of the Korean Society of Clothing and Textiles
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• v.36 no.9
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• pp.928-939
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• 2012

This study evaluates wear comforts of water-vapor-permeable (WVP) garments through a measurement of various parameters such as skin and rectal temperatures, microclimate between skin and clothing, sweat rate, and subjective sensations (thermal, wet and comfort sensations) to correlate the physiological responses of the human body with its comfort feeling. Wear comfort during a specific exercise on a treadmill in a climatic chamber (temperature T = $20{\pm}0.5^{\circ}C$ and relative humidity H = $50{\pm}10%$) were studied using eight men wearing seven sportswear outfits (a long sleeve shirts and a long pants) made with seven different WVP fabrics. A comfort sensation was found to be highly correlated with skin T (p<.001), microclimate (T and H) between skin and clothing (p<.001) and sweat rate (p<.05). A regression model correlating comfort sensations and physiological responses obtained from wearer trials could be established: Y = 14.167 - 0.362 ${\times}$ X1 + 0.424 ${\times}$ X2 - 0.238 ${\times}$ X3 - 0.561 ${\times}$ X4 + 0.253 ${\times}$ X5 + 0.214 ${\times}$ X6 - 0.393 ${\times}$ X7 + 0.023 ${\times}$ X8 - 0.043 ${\times}$ X9. (Y = comfort sensation, X1 = forehead skin T, X2 = forearm skin T, X3 = hand skin T, X4 = thigh skin T, X5 = T of chest microclimate, X6 = T of thigh microclimate, X7 = chest sweat rate, X8 = H of back microclimate, X9 = H of thigh microclimate. The regression model obtained in this work can be used by manufacturers to objectively estimate the comfort sensation of sportswear before it is introduced to the consumer market. This study provides salient information to sportswear manufacturers and sportswear consumers.