• Environmental Engineering Research
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• v.11 no.5
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• pp.241-249
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• 2006

A mathematical model is described for the prediction of convective upward transport of an organic solvent driven by evaporation at the surface, which is known as the major transport mechanism in the in-situ photolysis of a soil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin(TCDD). A finite-element model was proposed to incorporate the effects of multiphase flow on the distribution of each fluid, gravity as a driving force, and the use of hysteretic models for more accurate description of k-S-p relations. Extensive numerical calculations were performed to study fluid flow through three types of soils under different water table conditions. Predictions of relative permeability-saturation-pressure (k-S-p) relations and fluids distribution for an illustrative soil indicate that hysteresis effects may be quite substantial. This result emphasizes the need to use hysteretic models in performing flow simulations including reversals of flow paths. Results of additional calculations accounting for hysteresis on the one-dimensional unsaturated soil columns show that gravity affects significantly on the flow of each fluid during gravity drainage, solvent injection, and evaporation, especially for highly permeable soils. The rate and duration of solvent injection also have a profound influence on the fluid saturation profile and the amount of evaporated solvent. Key factors influencing water drainage and solvent evaporation in soils also include hydraulic conductivity and water table configuration.

• The Korean Journal of Physiology
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• v.25 no.2
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• pp.171-177
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• 1991

This study was carried out to determine effect of acute renal ischemia on transport function of organic cation, tetraethylammonium (TEA), in rabbit kidney proximal tubule. Clamping of the renal artery for 30 and 60 min produced a polyuria which was accompanied by an increase in $Na^+$ excretion. The capacity of kidney cortical slices to accumulate TEA was increased after 30 and 60 min of ischemia. When blood flow was restored for 30 min after 30 and 60 min of ischemia, the augmented TEA uptake was recovered to the control values. Oxygen consumption of cortical slices was stimulated after 30 min of ischemia, whereas it was not altered by 60 min of ischemia. A 90-min ischemia produced a significant inhibition of TEA uptake and tissue oxygen consumption. These results suggest that the basolateral transport system for organic cation persists after ischemic periods of 60 min despite evidence that tubular reabsorptive mechanism of $Na^+$ and water is markedly impaired. This may indicate that the active secretory systems of proximal tubule are more resistant to ischemic injury than the reabsorptive systems.

• Journal of Microbiology and Biotechnology
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• v.13 no.5
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• pp.666-672
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• 2003

Vacuolar degeneration of the gastric epithelial cells is a characteristic feature of the derangement of mucosa where Helicobacter pylori colonizes, and H. pylori vacuolating cytotoxin (VacA) has been suggested to playa key role in it. To elucidate the VacA-involved degenerative mechanism, VacA was purified, and its impact on degeneration of HeLa cells was determined. In the presence of ammonium chloride, cell vacuolation by VacA was dose-and time-dependent, however, no detectable degeneration of the cells was observed with the VacA concentration tested. A further increase of vacuolation was shown in cells pre-treated with diethyl pyrocarbonate (DEPC) , and this resulted in a change of the cell morphology to become spherical. Similar phenomena were also observed when HeLa cells were co-cultivated with intact H. pylori cells. It was remarkable to note that the degree of growth inhibition was proportional to the increase in vacuole formation, suggesting that the vacuolation rate would be critical for cell degeneration. Surprisingly, although VacA was itself inhibited by DEPC, its uptake was markedly increased by this agent, similar to that found in cells with Nabutyrate. These data indicate that the cell's tolerance of VacA transport may be critical for vacuolar degeneration and may be changeable during H. pylori inhabitation.

• The KSFM Journal of Fluid Machinery
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• v.5 no.1 s.14
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• pp.20-26
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• 2002

This study reports the analysis of the pressure drop characteristics for the air-particle flow in powder transport piping system. The pressure drop characteristics of air-particle flow in piping system is not well understood due to the complexity of particles motion mechanism. Particles or powders suspended in air flow cause the increase of the pressure drop and affect directly the transportation efficiency. In this study, the pressure drop in powder transport piping system with straight and curved pipes is analyzed for the interactions of air flow and particle motion. The total pressure drop increases with increasing of the pipe length, the mixture ratio, and the friction factor of particles due to the increasing friction loss by air and particles in a coal piping system. For the coal powders of $74{\mu}m$ size and powder-to-air mass mixture ratio of 0.667, the total pressure drop by the consideration of powders and air flow is $30\%$ higher than that of air flow only.

• Biomolecules & Therapeutics
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• v.22 no.1
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• pp.68-72
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• 2014

When chemotherapy is administered during pregnancy, it is important to consider the fetus chemotherapy exposure, because it may lead to fetal consequences. Paclitaxel has become widely used in the metastatic and adjuvant settings for woman with cancer including breast and ovarian cancer. Therefore, we attempted to clarify the transport mechanisms of paclitaxel through blood-placenta barrier using rat conditionally immortalized syncytiotrophoblast cell lines (TR-TBTs). The uptake of paclitaxel was time- and temperature-dependent. Paclitaxel was eliminated about 50% from the cells within 30 min. The uptake of paclitaxel was saturable with $K_m$ of $168{\mu}M$ and $371{\mu}M$ in TR-TBT 18d-1 and TR-TBT 18d-2, respectively. [$^3H$]Paclitaxel uptake was markedly inhibited by cyclosporine and verapamil, well-known substrates of P-glycoprotein (P-gp) transporter. However, several MRP substrates and organic anions had no effect on [$^3H$]paclitaxel uptake in TR-TBT cells. These results suggest that P-gp may be involved in paclitaxel transport at the placenta. TR-TBT cells expressed mRNA of P-gp. These findings are important for therapy of breast and ovarian cancer of pregnant women, and should be useful data in elucidating teratogenicity of paclitaxel during pregnancy.

• Corrosion Science and Technology
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• v.16 no.4
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• pp.209-225
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• 2017

Development of high strength steel requires proper understanding of hydrogen behavior since the higher the steel strength the greater the susceptibility of hydrogen assisted cracking. This paper provides a brief but broad overview on hydrogen entry and transport behavior of high-strength ferritic steels. First of all, hydrogen absorption, diffusion and trapping mechanism of the steels are briefly introduced. Secondly, several experimental methods for analyzing the physical/chemical nature of hydrogen uptake and transport in the steels are reviewed. Among the methods, electrochemical permeation technique utilized widely for evaluating the hydrogen diffusion and trapping behavior in metals and alloys is mainly discussed. Moreover, a modified permeation technique accommodating the externally applied load and its application to a variety of steels are intensively explored. Indeed, successful utilization of the modified permeation technique equipped with a constant load testing device leads to significant academic progress on the hydrogen assisted cracking (HAC) phenomenon of the steels. In order to show how the external and/or residual stress affects mechanical instability of steel due to hydrogen ingress, the relationship among the microstructure, hydrogen permeation, and HAC susceptibility is briefly introduced.

• Nuclear Engineering and Technology
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• v.27 no.1
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• pp.1-7
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• 1995

The mechanism of radionuclide colloid transport in porous media was studied through modeling and experiment. A nondestructive column scanning system was developed to improve the traditional destructive core slicing method. With an aid of this system we could get much more results from one experiment. Neutron activated clay soaked with soluble isotopes was used as colloid suspension. Filtration coefficients obtained through the experiments show two families of colloids despite their size distribution. New modeling of polydispersed colloid transport was made with two lumped parameters. This new model simulates well. Among the soluble isotopes $^{l37}$Cs mowed mainly as a form of colloid, but $^{85}$ Sr did not.t.

• Journal of Ocean Engineering and Technology
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• v.20 no.4 s.71
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• pp.58-63
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• 2006

When the costal zone surrounded by a breakwater has a narrow vertical opening, currents in the vicinity of a narrow entrance can result in a jet flow, coinciding with the tide. Such a Tidal-Jet Generator(TJG) can change the water mass distribution and transport processes in the domain of influence of the jet. Also, it can decrease the residual time of them. In the present study, the water purification utilizing tidal jets in the coastal zone over constant bathymetry are estimated numerically, using a finite-difference numerical scheme, named the NS-MAC-TIDE method, which isbased on the fully 3D Navier-stokes(NS) equations. The shear velocity near the inlet of the TJG are predicted from the flow field simulation, and are assessed qualitatively with the development of scouring or sediment that is caused by the change of diffusion or sweeping flowup from the seabed of sediment particles. Finally, through solving a transport equation of concentration, the residual time related on mass transport processes and the flushing mechanism for water purification are investigated.

• ETRI Journal
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• v.38 no.1
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• pp.18-29
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• 2016

In this paper, we discuss the issues of providing protection for point-to-multipoint connections in both Ethernet and MPLS-TP-based packet transport networks. We introduce two types of per-leaf protection-linear and ring. Neither of the two types requires that modifications to existing standards be made. Their performances can be improved by a collective signal fail mechanism proposed in this paper. In addition, two schemes - tree protection and hybrid protection - are newly proposed to reduce the service recovery time when a single failure leads to multiple signal fail events, which in turn places a significant amount of processing burden upon a root node. The behavior of the tree protection protocol is designed with minimal modifications to existing standards. The hybrid protection scheme is devised to maximize the benefits of per-leaf protection and tree protection. To observe how well each scheme achieves an efficient traffic recovery, we evaluate their performances using a test bed as well as computer simulation based on the formulae found in this paper.

• Industrial Engineering and Management Systems
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• v.13 no.2
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• pp.221-230
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• 2014

With the progress and prosperity of commerce and industry, time and money increasingly form an equal partnership. Using air carriers to shorten the round-trip time has become an important choice for many people in the tourism process. Faced with increasing competition within the aviation service environment, airline evaluation criteria and the requirements of customers are gradually dominating the evaluation mechanism for air transport service quality. Over the past few years, attention on the transport quality of service has been primarily focused more on land-based transport, and less on the relevant evaluation criteria of airlines. Many studies have shown that quality of service will directly affect customer satisfaction, resulting in the fact that good quality aviation services have become increasingly important. Therefore, in practical industrial operations with limited resources, there is an urgent need to delve into the assessment guidelines that have an impact on customers when they choose an airline, which can be used as a basis for improving customer satisfaction. Through a literature review and a reliability and validity analysis, this study summarized 19 evaluation criteria, using the purposive sampling method and the decision laboratory method (DEMATEL). In addition, this study viewed the causal relationship between the evaluation criteria and the degree of association as a continuing project for airlines. This study selected appropriate empirical samples from two domestic airlines. The conclusions may provide recommendations for all airlines.