• 제목/요약/키워드: Transient test

검색결과 947건 처리시간 0.029초

Hypoadrenocortical Crisis-like Transient Hyponatremia and Hyperkalemia in a Near-Term Pregnant Dog (분만 직전의 개에서 급성 부신겉질저하증과 유사한 일과성 저나트륨혈증 및 고칼륨혈증 일례)

  • Kang Ji-houn;Kim Min-jun;Cho Min-haeng;Chang Dong-woo;Kang Hyun-gu;Kim Ill-hwa;Na Ki-jeong;Yang Mhan-pyo
    • Journal of Veterinary Clinics
    • /
    • 제22권4호
    • /
    • pp.450-452
    • /
    • 2005
  • A 3-year-old, 43kg, pregnant Great Pyrenese was examined for clinical signs of acute weakness and anorexia for 4 days. The dog was in lateral recumbency at referral. The rectal temperature was within reference range, and the respiratory and heart rates were 36 breaths/min and 58 beats/min, respectively. The abdomen was distended, and several puppies were palpated. The mean fetal head diameter was 2.8cm in the ultrasonographic examination. The initial complete blood count and serum biochemical examinations revealed mild dehydration, mud hyperglycemia, hypochloremia, hyperkalemia, hyponatremia, and low sodium-potassium ratio. Serum BUN and total cholesterol values were slightly high. Hypoadrenocortical crisis was suspected on the basis of signs of acute collapse, hyponatremia and hyperkalemia. Adrenal gland function was evaluated by an ACTH stimulation test. The baseline cortisol concentration was $18.6{\mu}g/dl$ and the concentration at 1 hour after administration of tetracosactrin (ACTH, Synacthen) was $8{\mu}g/dl$. The dog was treated for the correction of assumed hypoadrenocortical crisis and substantial hyperkalemia. In addition to rapid infusion with saline solution, other medications administered intravenously included sodium bicarbonate and cimetidine hydrochloride. The dog was monitored with repeated serum electrolyte examination. After clinical stabilization, cesarean section was performed. All of 13 puppies were delivered, and the dog recovered from anesthesia without complications. The values of postpartum blood tests returned to normal or within reference range. The dog remained healthily.

Single dose toxicity study of CKD-602, a new camptothecin anticancer agent, in Beagle dogs (개에서 새로운 캄토테신계 항암제 CKD-602의 단회투여독성시험)

  • Kim, Jong-Choon;Shin, Dong-Ho;Park, Seung-Chun;Son, Woo-Chan;Cha, Shin-Woo;Han, Junghee;Bae, Joo-Hyun;Suh, Jeong-Eun;Chung, Moon-Koo
    • Korean Journal of Veterinary Research
    • /
    • 제44권1호
    • /
    • pp.49-55
    • /
    • 2004
  • The present study was carried out to investigate the potential acute toxicity of CKD-602 by a single intravenous dose in Beagle dogs. The test chemical was administered intravenously to male and female Beagle dogs at dose levels of 0.3, 0.5, or 2.5 mg/kg. Mortalities, clinical findings, and body weight changes were monitored for the 14-day period following the administration. At the end of 14-day observation period, all animals were sacrificed and complete gross postmortem examinations were performed. All males and females of the 2.5 mg/kg dose group were found dead between the fourth and seventh day after the injection. Treatment related clinical signs, including vomiting, anorexia, mucous stool, diarrhea, and no stool were observed. Decrease or suppression of body weight was observed in a dose-dependent manner. In autopsy, dark red discoloration of the gastrointestinal tract, atrophy of the thymus, paleness of the spleen, sporadic dark red spots of the lung and petechia of the heart were observed in dead animals of the 2.5 mg/kg dose group. There were no specific adverse effects on males and females of the 0.3 and 0.5 mg/kg dose groups, except for the transient clinical signs such as anorexia, vomiting, and mucus/no stool. On the basis of the results, it was concluded that a single intravenous injection of CKD-602 to Beagle dogs resulted in increased incidence of abnormal clinical signs and death, decreased body weight, and increased incidence of abnormal gross findings. The absolute toxic dose of this chemical was 2.5 mg/kg for both genders. The $LD_{50}$ value was 1.1 mg/kg (95% confidence limit not specified) for both genders. The no-observed-effect level (NOEL) was considered to be below 0.3 mg/kg for both genders.

Heat Transfer Analysis and Experiments of Reinforced Concrete Slabs Using Galerkin Finite Element Method (Galerkin 유한요소법을 이용한 철근콘크리트 슬래브의 열전달해석 및 실험)

  • Han, Byung-Chan;Kim, Yun-Yong;Kwon, Young-Jin;Cho, Chang-Geun
    • Journal of the Korea Concrete Institute
    • /
    • 제24권5호
    • /
    • pp.567-575
    • /
    • 2012
  • A research was conducted to develop a 2-D nonlinear Galerkin finite element analysis of reinforced concrete structures subjected to high temperature with experiments. Algorithms for calculating the closed-form element stiffness for a triangular element with a fully populated material conductance are developed. The validity of the numerical model used in the program is established by comparing the prediction from the computer program with results from full-scale fire resistance tests. Details of fire resistance experiments carried out on reinforced concrete slabs, together with results, are presented. The results obtained from experimental test indicated in that the proposed numerical model and the implemented codes are accurate and reliable. The changes in thermal parameters are discussed from the point of view of changes of structure and chemical composition due to the high temperature exposure. The proposed numerical model takes into account time-varying thermal loads, convection and radiation affected heat fluctuation, and temperature-dependent material properties. Although, this study considered standard fire scenario for reinforced concrete slabs, other time versus temperature relationship can be easily incorporated.

A Study on Groundwater Flow Modeling in the Fluvial Aquifer Adjacent to the Nakdong River, Book-Myeon Area, Changwon City (창원시 북면 낙동강 주변 하성퇴적층의 지하수유동 모델링 연구)

  • Hamm Se-Yeong;Cheong Jae-Yeol;Kim Hyoung-Su;Hahn Jeong-Sang;Ryu Su-Hee
    • Economic and Environmental Geology
    • /
    • 제37권5호
    • /
    • pp.499-508
    • /
    • 2004
  • Changwon City first constructed riverbank filtration plants in Book-Myeon and Daesan-Myeon in Korea in the year 2001. This study evaluated hydrogeological characteristics and groundwater flow simulation between the Nakdong River and the fluvial aquifers adjacent to the river in Book-Myeon, Changwon City. The groundwater simulation calculated the influx rate from the Nakdong River and the fluvial aquifers to pumping wells through the riverbank filtration system. The groundwater flow model utilized drilling, grain size analysis, pumping test, groundwater level measurements, river water discharge and rainfall data. Hydraulic heads calculated by the steady-state model closely matched measured heads in pumping and observation wells. According to the transient flow model, using a total pumping amount of 14,000 $m^3$/day, the flux into the pumping wells from the Nakdong River accounts for 8,390 $m^3$/day (60%), 590 $m^3$/day (4%) is from the aquifer in the rectilinea. direction to the Nakdong River, and 5,020 $m^3$/day (36%) is from the aquifer in the parallel direction to the Nakdong River. The particle tracking analysis shows that a particle from the Nakdong River moves toward the pumping wells at a rate of about 1.85 m/day and a particle from the aquifer moves toward the pumping wells at a rate of about 0.75 m/day. This study contributes to surface water/groundwater management modeling, and helps in understanding, how seasonal change affects pumping rates, water quality, and natural recharge.

Effect Analysis for Frequency Recovery of 524 MW Energy Storage System for Frequency Regulation by Simulator

  • Lim, Geon-Pyo;Choi, Yo-Han;Park, Chan-Wook;Kim, Soo-Yeol;Chang, Byung-Hoon;Labios, Remund
    • KEPCO Journal on Electric Power and Energy
    • /
    • 제2권2호
    • /
    • pp.227-232
    • /
    • 2016
  • To test the effectiveness of using an energy storage system for frequency regulation, the Energy New Business Laboratory at KEPCO Research Institute installed a 4 MW energy storage system (ESS) demonstration facility at the Jocheon Substation on Jeju Island. And after the successful completion of demonstration operations, a total of 52 MW ESS for frequency regulation was installed in Seo-Anseong (28 MW, governor-free control) and in Shin-Yongin (24 MW, automatic generation control). The control system used in these two sites was based on the control system developed for the 4 MW ESS demonstration facility. KEPCO recently finished the construction of 184 MW ESS for frequency regulation in 8 locations, (e.g. Shin-Gimjae substation, Shin-Gaeryong substation, etc.) and they are currently being tested for automatic operation. KEPCO plans to construct additional ESS facilities (up to a total of about 500 MW for frequency regulation by 2017), thus, various operational tests would first have to be conducted. The high-speed characteristic of ESS can negatively impact the power system in case the 500 MW ESS is not properly operated. At this stage we need to verify how effectively the 500 MW ESS can regulate frequency. In this paper, the effect of using ESS for frequency regulation on the power system of Korea was studied. Simulations were conducted to determine the effect of using a 524 MW ESS for frequency regulation. Models of the power grid and the ESS were developed to verify the performance of the operation system and its control system. When a high capacity power plant is tripped, a 24 MW ESS supplies power automatically and 4 units of 125MW ESS supply power manually. This study only focuses on transient state analysis. It was verified that 500 MW ESS can regulate system frequency faster and more effectively than conventional power plants. Also, it was verified that time-delayed high speed operations of multiple ESS facilities do not negatively impact power system operations. It is recommended that further testing be conducted for a fleet of multiple ESSs with different capacities distributed over multiple substations (e.g. 16, 24, 28, and 48 MW ESS distributed across 20 substations) because each ESS measures frequency individually. The operation of one ESS facility will differ from the other ESSs within the fleet, and may negatively impact the performance of the others. The following are also recommended: (a) studies wherein all ESSs should be operated in automatic mode; (b) studies on the improvement of individual ESS control; and (c) studies on the reapportionment of all ESS energies within the fleet.

Development of 1.2[kW]Class Fuel Cell Power Conversion System (1.2[kW]급 연료전지용 전력변환장치의 개발)

  • Suh, Ki-Young;Kim, Chil-Ryong;Cho, Man-Chul;Kim, Jung-Do;Yoon, Young-Byun;Kim, Hong-Sin;Park, Do-Hyung;Ha, Sung-Hyun
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
    • /
    • 제21권6호
    • /
    • pp.117-125
    • /
    • 2007
  • Recently, a fuel cell with low voltage and high current output characteristics is remarkable for new generation system. It needs both a DC-DC step-up converter and DC-AC inverter to be used in fuel cell generation system. Therefor, this paper, consists of an isolated DC-DC converter to boost the fuel cell voltage 380[VDC] and a PWM inverter with LC filter to convent the DC voltage to single-phase 220[VAC]. Expressly, The fuel cell system which it proposes DC-DC the efficient converter used PWM the phase transient control law and it depended to portion resonance ZVS switching, loss peek voltage and electric current of realization under make schedule, switching frequency anger and the switch reduction. And mind benevolence it sprouted 2 in stop circuit and it added and a direct current voltage and the electric current where the ingredient is reduced in load side ripple stable under make whom it will be able to supply. Besides the efficiency of 92[%]is obtained over the wide output voltage regulation ranges and load variations. Also, under make over together the result leads simulation and test, the propriety confirmation.

Impacts of wave and tidal forcing on 3D nearshore processes on natural beaches. Part I: Flow and turbulence fields

  • Bakhtyar, R.;Dastgheib, A.;Roelvink, D.;Barry, D.A.
    • Ocean Systems Engineering
    • /
    • 제6권1호
    • /
    • pp.23-60
    • /
    • 2016
  • The major objective of this study was to develop further understanding of 3D nearshore hydrodynamics under a variety of wave and tidal forcing conditions. The main tool used was a comprehensive 3D numerical model - combining the flow module of Delft3D with the WAVE solver of XBeach - of nearshore hydro- and morphodynamics that can simulate flow, sediment transport, and morphological evolution. Surf-swash zone hydrodynamics were modeled using the 3D Navier-Stokes equations, combined with various turbulence models (${\kappa}-{\varepsilon}$, ${\kappa}-L$, ATM and H-LES). Sediment transport and resulting foreshore profile changes were approximated using different sediment transport relations that consider both bed- and suspended-load transport of non-cohesive sediments. The numerical set-up was tested against field data, with good agreement found. Different numerical experiments under a range of bed characteristics and incident wave and tidal conditions were run to test the model's capability to reproduce 3D flow, wave propagation, sediment transport and morphodynamics in the nearshore at the field scale. The results were interpreted according to existing understanding of surf and swash zone processes. Our numerical experiments confirm that the angle between the crest line of the approaching wave and the shoreline defines the direction and strength of the longshore current, while the longshore current velocity varies across the nearshore zone. The model simulates the undertow, hydraulic cell and rip-current patterns generated by radiation stresses and longshore variability in wave heights. Numerical results show that a non-uniform seabed is crucial for generation of rip currents in the nearshore (when bed slope is uniform, rips are not generated). Increasing the wave height increases the peaks of eddy viscosity and TKE (turbulent kinetic energy), while increasing the tidal amplitude reduces these peaks. Wave and tide interaction has most striking effects on the foreshore profile with the formation of the intertidal bar. High values of eddy viscosity, TKE and wave set-up are spread offshore for coarser grain sizes. Beach profile steepness modifies the nearshore circulation pattern, significantly enhancing the vertical component of the flow. The local recirculation within the longshore current in the inshore region causes a transient offshore shift and strengthening of the longshore current. Overall, the analysis shows that, with reasonable hypotheses, it is possible to simulate the nearshore hydrodynamics subjected to oceanic forcing, consistent with existing understanding of this area. Part II of this work presents 3D nearshore morphodynamics induced by the tides and waves.

Design of an Excitation System for Simulating Wind-Induced Response and Evaluating Wind-load Resistance Characteristics (건축구조물의 풍하중 구현 및 풍특성 평가를 위한 가진시스템 설계)

  • Park, Eun-Churn;Lee, Sung-Kyung;Min, Kyung-Won;Chun, Lan;Kang, Kyung-Soo;Lee, Sang-Hyun
    • Journal of the Computational Structural Engineering Institute of Korea
    • /
    • 제20권6호
    • /
    • pp.769-778
    • /
    • 2007
  • In this paper, excitation systems using linear mass shaker (LMS) and active tuned mass damper (ATMD) are presented in order to simulate the wind induced responses of a building structure. The actuator force for the excitation systems is calculated by using the inverse transfer function of a target structural response to the actuator. Filter and envelop function are used such that the error between the wind and actuator induced responses is minimized by preventing the actuator from exciting unexpected modal response and initial transient response. The analyses results from a 76-story benchmark building problem in which wind load obtained by wind tunnel test is given, indicate that the excitation system installed at a specific floor can approximately embody the structural responses induced by the wind load applied to each floor of the structure. The excitation system designed by the proposed method can be effectively used for evaluating the wind response characteristics of a practical building structure and for obtaining an accurate analytical model of the building under wind load.

A Study on Estimation of Initial Gas in Place for Coalbed Methane Field Using Production Data at Canada (생산자료를 이용한 캐나다 CBM 원시부존량 평가 연구)

  • Seo, Hyeongjun;Moon, Bryan;Kim, Kihong;Han, Jungmin;Kwon, Sunil
    • Journal of the Korean Institute of Gas
    • /
    • 제22권1호
    • /
    • pp.64-77
    • /
    • 2018
  • This paper presents the prediction of the original gas in place(OGIP) by using the material balance method and decline curve analysis method with production history and pressure transient test data for four coalbed methane wells in the Horseshoe Canyon field. In this study, the conventional gas equation and the Jensen and Smith(J&S) equation were used to material balance analysis, and the Arps' empirical correlation and Khaled method were applied to decline curve analysis. From the results, the OGIP estimated from the conventional gas and the J&S method was small in difference as under 12%. Also, in case of decline curve analysis, it was found that the Khaled method has appropriated to calculate the OGIP, because the OGIP was estimated as unlimited value by the Arps' equation from the decline exponent of 1 - 3.5. The OGIP difference between conventional gas method and Khaled method was calculated as 8.67% ~ 31.04%, and those between J&S method and Khaled method was 13.67% ~ 26.49%.

A Development of 3-D Numeric Model for the Confined Flow and Discharge under Sea Ground (해저 지중 피압유체의 흐름과 양수량 산출에 관한 3차원 수치모형의 개발)

  • Kim, Sang-Jun
    • Journal of Korean Society of Coastal and Ocean Engineers
    • /
    • 제22권6호
    • /
    • pp.387-396
    • /
    • 2010
  • A 3-D numeric model for the confined transient flow under sea ground have been developed. This is FDM model using Gauss-Seidel SOR (successive over-relaxation). This model shows the similar head distribution pattern to Theis analytic solution and MODFLOW simulation. The input flowrate to the aquifer and discharge of well have been compared. And it have been found that mass balance is influenced by the weight factor ${\alpha}$, i.e. fullyimplicit method (${\alpha}$=1) shows 5% error, but when ${\alpha}$ becomes to 0.5(Crank and Nicolson method) the mass balance becomes worse and the model result diverges. And the convergency of the model is not much different when $\lambda$ (over-relaxation factor)=0.8~1.5, but when $\lambda$>1.5, the model result diverges. The test-run shows that the well discharge becomes smaller when another well is near. This model can cover the isotropy$(Kx{\neq}Ky{\neq}Kz)$ and inhomogeneity, and can be used for the selection of well site, discharge calculation, and head prediction in case of the artificial recharge etc.