• Journal of Oral Medicine and Pain
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• 제43권3호
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• pp.84-86
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• 2018

Salivary and lacrimal gland dysfunction is relatively frequent after radioiodine therapy. In most cases this is a transient side effect, but in some patients it may persist for a long period or appear late. Radioiodine ($^{131}I$) therapy is often administered to patients following total thyroidectomy to treat well-differentiated follicular cell-derived thyroid cancer. In addition to the thyroid, $^{131}I$ accumulates in the salivary glands, giving rise to transient or permanent salivary gland damage. Salivary gland dysfunction following radioiodine therapy can be caused by radiation damage. But, it also may be associated with $Sj{\ddot{o}}gren$ syndrome (SS) developed after radioiodine therapy. It would be recommended that the evaluation for SS including anti-SSA/Ro and anti-SSB/La should be considered before and after radioiodine therapy.

• Nuclear Engineering and Technology
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• 제55권1호
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• pp.209-214
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• 2023

The effect of thermal annealing on defect recovery of in-core neutron-irradiated 4H-SiC was investigated. Au/SiC Schottky diodes were manufactured using a 4H-SiC epitaxial wafer that was neutron-irradiated at the HANARO research reactor. The electrical characteristics of their epitaxial layers were analyzed under various conditions, including different neutron fluences (1.3 × 10¹⁷ and 2.7 × 10¹⁷ neutrons/cm²) and annealing times (up to 2 h at 1700 ℃). Capacity-voltage measurements showed high carrier compensation in the neutron-irradiated samples and a recovery tendency that increased with annealing time. The carrier density could be recovered up to 77% of the bare sample. Deep-level-transient spectroscopy revealed intrinsic defects of 4H-SiC with energy levels 0.47 and 0.68 eV below the conduction-band edge, which were significantly increased by in-core neutron irradiation. A previously unknown defect with a high electron-capture cross-section was discovered at 0.36 eV below the conduction-band edge. All defect concentrations decreased with 1700 ℃ annealing; the decrease was faster when the defect level was shallow.

• 천문학회보
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• 제44권2호
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• pp.60.4-60.4
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• 2019

Small bodies in the solar system are pristine leftovers of planetesimals since the formation epoch (~4.6 Gyr ago). After the formation, icy planetesimals have been preserved in the distant cold place beyond 30 au (i.e., Trans-Neptunian region) until recently without any catastrophic processes but have just been injected into inner region (<~5 au from the Sun) to be observed as comets. On the contrary, asteroids are rocky primitive objects (although some of them contains icy volatiles) distributing in the mainbelt between Mars and Jupiter orbits. Because of frequent encounters in the mainbelt, asteroids have experienced a number of repeated impacts until the present day. Namely, it is important to investigate thermal alternation process of cometary volatiles and refractories in the solar radiation field, whereas collisional and subsequence phenomena of asteroidal bodies. Although recent spacecraft observations revealed the physical natures on the surfaces of comets and asteroids, their interiors still remain largely unexplored. It is likely that a sudden brightening of a comet is associated with rapid sublimation of internal CO and CO2 or phase transition of amorphous H2O. An episodic dust ejection from an asteroid is causally related to an impact among asteroids, sudden sublimation of remaining subsurficial volatiles, etc. Because these transient phenomena provide rare opportunities to investigate their interiors, immediate observations using any optical instruments are particular important. In my presentation, I will review some examples of such transient phenomena in the solar system and propose possible collaborative research using the Korean Small Telescope Network.

• Molecules and Cells
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• 제25권1호
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• pp.105-111
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• 2008

Radiotherapy is an important treatment for many malignant tumors, but there are recent reports that radiation may increase the malignancy of cancer cells by stimulating expression of type IV collagenases. In this study, we examined changes in matrix metalloproteinase (MMP) inhibitors, such as the tissue inhibitors of metalloproteinase (TIMP)-1, TIMP-2 and RECK, in response to irradiation in Panc-1 pancreatic cancer cells. Irradiation increased RECK protein levels but not mRNA levels, whereas no significant changes were found in TIMP-1 and TIMP-2. The enhanced RECK protein levels were associated with an increase in MMP inhibitory activity. However, irradiation slightly but reproducibly increased the invasiveness of the Panc-1 cells. Like irradiation, treatment of Panc-1 cells with transforming growth factor $(TGF)-{\beta}1$ led to a 2-fold increase in RECK protein levels. Transient transfection with Smad3 also increased RECK protein levels, but transfection with Smad7 markedly reduced them. Stable expression of Smad7 and treatment with SB431542, an inhibitor of $TGF-{\beta}$ receptor I kinase, abolished $TGF-{\beta}1$- and radiation-mediated effects on RECK. Furthermore, irradiation increased levels of phosphorylated Smad3. We conclude that radiation post-transciptionally enhances RECK protein levels in Panc-1 cells, at least in part, via $TGF-{\beta}$ signaling, and that irradiation increases Panc-1 invasiveness via a mechanism that may not be linked to MMP-2 activity.

• Journal of Korean Neurosurgical Society
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• 제29권10호
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• pp.1345-1351
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• 2000

Objective : Around the sellar area, there are many important structures. But, the optimal radiation dosage for minimal toxicity to surrounding neural tissue has not been firmly established. The purpose of this study is to evaluate the radiosurgical outcome of juxtasellar tumors and to investigate the relationship between radiation dosage and toxicity to neural tissue. Method : Between May 1992 and June 2000, we treated 65 juxtasellar tumors by using the Leksell Gamma Knife. Among them, 52 patients who could be followed more than 1 year were included in this study. The radiosurgical dosage to the optic pathway, cavernous sinus, Meckel's cave, hypothalamus, pituitary gland and stalk, and brain stem was analyzed and correlated with clinical outcome. The mean follow-up period was 33.5 months(range 12.2- 99.0 months). Result : The clinical response rate was 69.2%. The volume response rate was 61.0% and the radiologic control rate was 92.7%. There were 4 complications(7.7%) of 2 trigeminal neuropathy, 1 abducens nerve palsy, and 1 trigeminal and transient abducens nerve palsy. The optic apparatus appeared to tolerate doses greater than 10Gy. The risk of cranial nerve complications in cavernous sinus seemed to be related to doses of more than 16Gy. In 3 of 4 patients who received more than 16Gy to cavernous sinus, the abducens or trigeminal neuropathy occurred. Also, one patient who received more than 15Gy to the Meckel's cave, trigeminal neuropathy developed. The hypothalamus, pituitary gland and stalk, and brain stem were relatively tolerable to radiation. Conclusion : Gamma Knife radiosurgery seems to be an effective method to control the growth of juxtasellar tumors. To avoid injury to surrounding important neural tissue, careful dose planning and further study for radiation toxicity to neural tissue were needed.

• 한국태양에너지학회 논문집
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• 제36권4호
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• pp.49-56
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• 2016

The objective of this work is to analyze the variation in energy performance for each flat plate collector connected in series. In this study, it was assumed that solar water heating system with annual solar fraction of 60% was installed in an office building in Seoul, South Korea. The transient energy performance corresponding to four cases, which are selected using different solar radiation and outdoor air temperature, is studied by analyzing the variation in outlet temperature, solar useful heat gain, and thermal efficiency of each collector. It is observed that the useful heat gain and the collector efficiency decrease continuously, and outlet temperature increases when increasing the number of collector connected in series. The long-term performance is assessed by evaluating the thermal efficiency of each collector for two solar radiation conditions ranging from 780 to $820W/m^2$ and from 380 to $420W/m^2$. It is found that the differences between the intercept and slope of the efficiency curves for first and eighth collectors are 3.68% and 6.74% for solar radiation of $800{\pm}20W/m^2$ and 8.57% and 12.90% for solar radiation of $400{\pm}20W/m^2$, respectively. In addition, it is interesting to note that annual useful heat gain and collector efficiency are reduced with similar rate of about 6.13% when increasing the collector area by connecting the collectors in series.

• Journal of KIEE
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• 제11권1호
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• pp.32-40
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• 2001

This paper presents the detailed statistics on radiation field signatures associated with multiple-intracloud lightning discharges. A transient signal recording system was used to measure the electric and magnetic fields produced by lightning flashes. The measurements were made in th summers of 1995 through 1999, and the location of the observation station was in Inchon on the coast of the Yellow Sea in Korea(37$^{\circ}$25'N, 126$^{\circ}$ 39'E). Most of lightning flashes typically contains between two and five strokes. The individual intracloud stork radiation fields were the bipolar pulse. On the average, the ratio of the peak of the second stroke to the first stroke peak was 75.1$\pm$40.1% for the negative, and a fraction of the subsequent stroke peaks were higher than the first stroke peak. The greater the number of the subsequent stroke order, less time separations between strokes were produced. The mean of the depth of the dip was 81.2$\pm$27.9% for the positive polarity and 75.9$\pm$24.4% for the negative. The depth of the dip increased for the positive bipolar pulses and decreased for the negative as the number of the stroke order increased.

• 에너지공학
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• 제12권1호
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• pp.11-16
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• 2003

지상 정적 상태에 있는 항공기내 연료온도의 변화가 유한차분식에 의하여 해석되었다. 수정 Dufort-Frankel 기법의 explicit 방법에 의해 수치계산이 수행되었다. 항공기는 지상 정적상태에서 1% hot day 대기조건에 따른 태양의 복사 및 바람의 속도와 함께 반복되는 일일주기의 공기온도에 노출되어 있다고 가정되었다. 항공기는 난류유동장내에 있는 것으로 가정되었다. 항공기 표면과 외부대기사이의 열전달을 계산하기 위하여 Eckert에 의해 제안된 평판위의 난류 열전달계수가 사용되었다. 본 해석에 사용된 지배방정식은 연료에 대한 에너지방정식이다. 본 해석으로부터, 주익탱크의 연료온도가 다른 탱크들 가운데 가장 높게 나타났으며 온도변화율 또한 가장 크게 나타났다. 본 온도해석에 대한 결과는 여러 비행임무에 있어서 항공기내의 연료온도 변화 해석을 위한 초기치로서 사용될 수 있다. 또한, 본 해석방법은 항공기 열에너지 관리시스템의 해석 및 설계에 사용될 수 있다.

• 대한기계학회논문집A
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• 제26권11호
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• pp.2297-2304
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• 2002

Two-dimensional and three-dimensional finite element methods have been used to analyze the deformation behavior of a shadow mask due to thermal and tension load. The shadow mask inside the Braun tube of a TV set has numerous slits through which the electron beams are guided to land on the designed phosphor of red, green or blue. Its thermal deformation therefore causes landing shift of the electron beam and results in decolorization of a screen. For the realistic finite element analysis, the effective thermal conductivity and the effective elastic modulus arc calculated, and then the shadow mask is modeled as shell without slits. Next a transient thermal analysis of the shadow mask is performed, wherein thermal radiation is a major heat transfer mechanism. Analysis of the resulting thermal deformation is followed, from which the landing shift of the electron beam is obtained. The present finite element scheme may be efficiently used to reduce thermal deformation of a shadow mask and in developing prototypes of a large screen flat TV.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 추계학술대회 논문집
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• pp.274-278
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• 2002

Surface finishing is still indispensable for most rapid prototyping (RP) processes because of the inherent stair-stepped surface and shrinkage of the parts. These problems can be minimized in the $VLM-_ST$ Process, because it uses expandable polystyrene foam sheets, each of which has a thickness of3.9 mm and a linear-interpolated side slope. The use of thick layers, however, limits the process capability of constructing fine details. This study focuses on the design of post-processing tool for fine details of $VLM-_ST$ parts and investigation of thermal characteristics during EPS foam cutting using the post-processing tool. To calculate the heat flux from the tool into the foam sheet, the tool was modeled as a heat source of radiation for finite element analysis. Results of the analysis agreed well with those of the experiment.