• Journal of The Korean Society of Integrative Medicine
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• v.9 no.3
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• pp.155-164
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• 2021

Purpose : The purpose of this study is to investigate the effects of transcranial direct current stimulation and virtual reality program application on cognition and depression of patients with mild cognitive impairment, and to find an intervention method that can enhance active participation of patients with mild cognitive impairment. Methods : In this study, 50 mild cognitive impairment patients were divided into a treatment group (25 patients) and a control group (25 patients). The treatment group was applied with a transcranial direct current stimulation and a virtual reality program, while the control group received a placebo transcranial direct current stimulation and a virtual reality program. Both groups received five 50-minute sessions per week (one session per day) for six weeks (total of 30 sessions). NCSE was used to evaluate the cognitive functions of the patients before and after treatment intervention. Moreover, K-BDI was conducted to examine the depression of the patients. Results : As a result of the transcranial direct current stimulation and a virtual reality program intervention, the cognitive function of both treatment and control group significantly (p<.05) improved, and the depression of both treatment and control group significantly (p<.05) decreased. Moreover, the changes in cognitive functions and depression were significant between the two groups¸ treatment and control group (p<.05). Conclusion : The results of the study showed that the application of the transcranial direct current stimulation and virtual reality program significantly improved the cognitive function of mild cognitive impairment patients and decreased the depression of them. Therefore, it could be concluded that the transcranial direct current stimulation and virtual reality program was an intervention method which positively affects the cognitive function and depression of mild cognitive impairment patients.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.2
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• pp.109-117
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• 2023

Purpose : Transcranial direct current stimulation is noninvasive method of cerebral cortical stimulation applied as an intervention to facilitate recovery in stroke patients. The purpose of this study was to examine the effects of transcranial direct current stimulation on depression and anxiety in stroke patients with the aim to finding a reliable method to reduce depression and anxiety in stroke patients. Methods : This study was conducted at A hospital located in D city from December 2022 to February 2023. Patients diagnosed with stroke were selected according to predefined study criteria and divided into two groups. 9 patients in experimental group underwent transcranial direct current stimulation and traditional occupational therapy, while 9 patients in the control group underwent sham transcranial direct current stimulation and traditional occupational therapy for 20 min per session 3 times per week for a total of 8 weeks. Beck depression inventory (BDI) and Beck anxiety inventory (BAI) were used to evaluate depression and anxiety in the patients before and after intervention. Wilcoxon signed rank test was used to compare differences before to after intervention. Mann-Whitney U test was used to compare the two groups. Differences with p<.05 were considered statistically significant. Results : First, both the experimental and control groups presented significant statistical difference before and after intervention on depression (p<.01). Comparison of two groups after intervention showed significant statistical difference in depression (p<.05). Second, the groups presented significant statistical difference before and after intervention on anxiety (p<.01). After intervention, the two groups showed significant statistical difference in anxiety (p<.05). Conclusion : Results of the present study demonstrated the effects of transcranial direct current stimulation on depression and anxiety in stroke patients, suggesting it may be a useful method of rehabilitation in this patient population; as such, further studies are warranted.

• The korean journal of orthodontics
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• v.36 no.2 s.115
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• pp.136-144
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• 2006

The purpose of this study was to determine whether association exists between temporomandibular joint (TMJ) characteristics in transcranial radiographs and TMJ internal derangement and to evaluate the validity of transcranial radiographs in diagnosis of internal derangement. Transcranial radiographs and magnetic resonance imaging (MRI) of 113 TMJs from 76 subjects were used for this study and all TMJs were classified into 3 groups according to the results of MRI: normal disk position, disk displacement with reduction, and disk displacement without reduction. Transcranial analysis included linear measurement of joint spaces and condylar head angle measurement. To determine any relationship between transcranial measurements according to disk displacement, one-way ANOVA was used. The results showed that condyle-fossa relationship in standard transcranial radiographs had no relationships with disk displacement. And, as disk displacement progressed, condylar angle between head and neck increased significantly. This result can be interpreted that condylar head angle reflects structural hard tissue change according to internal derangement progress. But this is insufficient in the determination of internal derangement. Therefore, although still clinically helpful, the validity of standard transcranial radiographs to diagnose TMJ internal derangement was questioned.

• The korean journal of orthodontics
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• v.28 no.1 s.66
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• pp.113-122
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• 1998

Stabilization splint therapy Precedes orthodontic intervention to enable the operator to find a 'true' centric(which is stable and comfortable), to test the patient's response to a change in the occlusion, prior to embarking upon a complex course of occlusal therapy : and finally, to see if the centric relation position can be stabilized. For this study, 47 malocclusion Patients enrolled for orthodontic treatment at the Department of Orthodontics, College of Dentistry, Chosun University comprised the malocclusion group, little variation of growth factor by the second molar eruption. They had Cr-Co discrepancy beyond normal range. For each patients the stabilization splint with mutually protected type of occlusal scheme was applied for 3 months. Condylar positions in CR and CO were measured using Penadent articulators, Panadent condylar position indicator(CPI), and transcranial projection before & after stabilization splint therapy. On the basis of this study, the results of this study were as follows 1. In all samples using CPI, there were statistical significances in CR-CO discrepancy(p<0.001) both before 8t after stabilization splint therapy. 2. In Rt and Lt+Rt/2 of superior joint space using transcranial projection, there were statistical significances in CR-CO discrepancy({<0.05) before & after stabilization splint therapy. 3. In supero-inferior components using CPI, there were statistical significances in CR-CO discrepancy(p<0.01) before & after stabilization splint therapy. 4. In all components except Rt using transcranial projection, there were no statistical significances in CR-CO discrepancy(p>0.05) before & after stabilization splint therapy. To sum up, CPI might be more effective than transcranial projection to reveal the changes between CR-CO discrepancies and stabilization splint might be more useful appliance for displaying the vertical changes, than the antero-posterior changes, of condylar position.

• The Journal of Korean Medicine
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• v.17 no.1 s.31
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• pp.171-189
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• 1996

Background and Purpose: The greater part of patients to visit Hospital of Oriental Medicine suffer from cerebrovascular accident(CVA). There is transcranial Doppler(TCD) in the diagnostic method to confirm cerebrovascular accident(CVA). Transcranial Doppler(TCD) is an accurate method of monitoring the blood flow velocities of the cerebral vessels and have been generally used to prevent symptomatic vasospasm and confirm cerebral infarction. So we studied, in the crebrovascular accident(CVA), to estimate whether transcranial Doppler(TCD) is useful to. Methods: Using transcranial doppler(Multigon Model 500M Transcranial Doppler System), we measured the mean and peak velocity and the direction of blood flow in 10 cerebrovascular accident(CVA)'s subjects who had been examined by Computed Tomography(CT) or Magnetic Resonance Imaging (MRI). Results : As an anticipation, in cerebrovascular accident(CVA)'s subject with Cb-infarction, the mean and peak velocity of blood flow fell down remarkably and the direction of blood flow was change or irritable. But didn't find out any signal in lacunar infarction. Also, in case with spontaneous hemorrhage, the velocity and direction of blood flow was change but this signal was short of diagnosis for Cb-hemorrhage. Besides, we found signals about embolism, stenosis, thrombosis and occlusion in cerebrovascular accident(CVA)'s subjects. Conclusion: In Cb-infarction, the result of TCD was equal to diagnosis with Computed Tomography(CT) or Magnetic Resonance Imaging (MRI). But about lacunar infarction or spontaneous hemorrhage, signals of TCD couldn't be found out or was insufficient more than Computed Tomography(CT) or Magnetic Resonance Imaging(MRI). In cerebrovascular accident(CVA)'s subject with embolism, stenosis, thrombosis or occlusion, signals of TCD were found out more than Computed Tomography(CT) or Magnetic Resonance Imaging(MRI). Therefore transcranial doppler(TCD) is necessary method which makes a diagnosis of cerebrovascular accident(CVA), with Computed Tomography(CT) or Magnetic Resonance Imaging(MRI).

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.27 no.2
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• pp.117-125
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• 1997

The purpose of this study was to evaluate the detectability of various radiographic techniques for mandibular condylar lesions. Erosive lesion, osteophyte and flattening were formed on the artificial mandibular condyle, and panoramic, transcranial, transorbital radiography, lateral and frontal tomography were taken. The results were as follows; 1. The detectability for erosive lesions was superior in the order of frontal tomography(96％), lateral tomography(78％), transorbital(59％), transcranial(16％) and panoramic(48％) radiography. 2. The location of erosive lesion that showed the highest detectability was the medial third in panoramic, the lateral third in transcranial, the central portion of anteroposterior direction in transorbital, the central portion of mediolateral direction and the posterior third in lateral tomography. Frontal tomography disclosed all erosive lesions except one anterolateral lesion. 3. The detectability of osteophyte was 100％ in lateral tomography, 78％ in transcranial and 56％ in panoramic radiography. 4. For flattening, lateral tomography showed the flattened condyle, but both panoramic and transcranial views showed only decreased bone density without the change of condylar shape.

• The korean journal of orthodontics
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• v.23 no.3 s.42
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• pp.405-414
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• 1993

Among the radiographs for temporomandibular joint, transcranial radiograph is widely used for screening and diagnosing temporomandibular disorder because it has sharp image and it is easy to take. This study was performed to compare condylar position and image sharpness in standard and individually corrected transcranial radiographs using Accurad-200 headholder. Submentovertex view, Reverse-Towne view, Standard and individually corrected transcranial radiographs of 45 university students who were randomly selected were traced, measured and analyzed. The results were as follows : 1. The means of condylar axes and lateral slopes were $16.8^{\circ}\;and\;22.5^{\circ}$ respectively. There were no differences between male and female or right and left side. 2. Individually corrected radiographs showed smaller posterior joint ,space and larger anterior joint space than standard radiographs, but superior joint space did net show a statistical difference between standard and individually corrected radiographs. 3. While a large number$(42.2\%)$ of the standard radiographs showed concentric condylar position, lots of(57.8) condylar positions were retropositioned in the individually corrected radiographs. 4. The image sharpness was inferior in the individually corrected radiographs to that of the standard radiographs.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.10 no.2
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• pp.37-42
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• 2012

Purpose : This study is to examine the effect of electrode size during transcranial direct current stimulation on hand function. Methods : By randomly assigning 26 right hand dominant subjects to two groups (I: carbon rubber electrode / II: disposable circular self-adhesive electrodes) with 13 subjects in each group depending on the electrode size, a positive electrodeof transcranial direct current stimulation was placed on the primary motor area (C4) and a negative electrode was placed on the left primary motor area (C3) and the stimulation was applied for 20 minutes.Hand function assessment before and after transcranial direct current stimulation were measured with JTT (Jebsen-Taylor hand function test). Results : According to hand function assessment by JTT, there were no interactions on both hands, and statistically significant differences according to time appeared in the main effect test. Conclusion : Regardless of the electrode size, it appears that transcranial direct current stimulation on the primary motor area activated hand function affected.

• Imaging Science in Dentistry
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• v.38 no.2
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• pp.89-93
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• 2008

Purpose: To evaluate the difference of the movement of the mandibular condyles between trans cranial and panoramic TMJ radiographs to view the movement of the mandibular condyles. Materials and Methods: Thirty-four paired transcranial and panoramic TMJ radiographs of patients were used to evaluate the movement of the mandibular condyle. The distances, from the most superior point of the mandibular condyle to the most inferior point of the articular eminence on both radiographs, were measured. The measurements were taken at closed state and maximum opening state of each radiograph on both side. Differences between matched pairs were analysed by paired t-test, with significance established at P<0.05. Results and Conclusion: The mean distance, from the most superior point of the mandibular condyle to the most inferior point of the articular eminence on both radiographs, was statistically different at each side (P<0.05). At closing state, the mean distance measured on panoramic TMJ radiographs was longer than on transcranial radio-graphs (0.85 mm at right side, 1.20 mm at left side). But at maximum opening state, the mean distance on transcranial radiographs was longer (1.00 mm at right side, 0.62 mm at left side) than panoramic TMJ radiographs.

• Journal of Magnetics
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• v.16 no.3
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• pp.234-239
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• 2011

Transcranial magnetic stimulation utilizes the method of controlling applied time and changing pulse by output pulse through power density control for diagnosis purposes. Transcranial magnetic stimulation can also be used in cases where diagnosis and treatment are difficult since output pulse shape can be changed. As intensity, pulse range, and pulse shape of the stimulation pulse must be changed according to lesion, the existing sine wave-shaped stimulation treatment pulse poses limitations in achieving various treatments and diagnosis. This study actualized a new method of transcranial magnetic stimulation that applies a 3 Stage 2 Switch( power semiconductor 2EA) for controlling pulse repetition rate by achieving numerous switching control of stimulation coil. Intensity, pulse range, and pulse shape of output can be freely changed to transform various treatment pulses in order to overcome limitations in stimulation treatment presented by the previous sine wave pulse shape. The method of freely changing pulse range by using 3 Stage 2 Switch discharge method is proposed. Pulse shape, composed of various pulse ranges, was created by grafting PFN (Pulsed Forming Network) through AVR AT80S8535 one-chip microprocessor technology, and application in transcranial magnetic stimulation was achieved to study the output characteristics of stimulation treatment pulse according to delaying time of the trigger signal applied in section switch.