• Title/Summary/Keyword: Tp

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Paraganglioma of the Thyroid Gland Mimicking Medullary Thyroid Carcinoma (갑상선 수질암으로 오인된 갑상선 부신경절종 1예)

  • Lee, Sang Yeon;Lee, Won Yong;Jeong, Woo-Jin;Ahn, Soon-Hyun
    • Korean Journal of Head & Neck Oncology
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    • v.28 no.2
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    • pp.149-152
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    • 2012
  • Paraganglioma of the thyroid is a neuroendocrine tumor originating from the neural crest. To our knowledge, only 32 cases of thyroid paraganglioma(TP) have been reported to date. TP is difficult to distinguish from medullary thyroid cancer(MTC), hence correct diagnosis is seldom obtained preoperatively. Although immunohistochemistry is helpful for confirmation of TP, these markers are not specific for differential diagnosis between TP and MTC. Therefore, an index of suspicion is important when encountered with MTC with unusual features, or given pathology with neuroendocrine features and unusual immunohistochemical findings. The authors report a case of TP misdiagnosed as MTC at preoperative work-up and intraoperative frozen section analysis, with a review of the literature. The case depicts various immunohistochemical characteristics of the tumor.

Transferable R plasmid of Edwardsiella tarda isolated from diseased flounders, Paralichithys olivaceus (넙치에서 분리된 Edwardsiella tarda의 약제내성 전달성 R plasmid)

  • Kim, Eun-Heui
    • Journal of fish pathology
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    • v.12 no.2
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    • pp.115-121
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    • 1999
  • MIC test of 16 chemotherapeutic agents was performed on 24 isolates of Edwardsiella tarda collected from flounders. They revealed resistance against combinations of ampicillin, amoxicillin, erythromycin, flumequine, doxycycline(DOXY), nalidixic acid, novobiocin, oxolinic acid, oxytetracycline(OTC), thiamphenicol(TP) and sulfonamide. Two strains carried transferable R plasmid encoding Otc Kanamycin Tp and Otc chloramphenicol Doxy Tetracycline Tp, respectively. The R plasmids were not similar each other on the basis of their digestion pattern of restriction endonuclease, suggesting distribution of different transferable R plasmid among E. tarda from flounders.

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Effects of Plant on Pollutant Removal Rate n Surface-flow Constructed Wetlands (자유수면형 인공습지에서 식물식재 유무가 처리효율에 미치는 영향)

  • Ham, Jong-Hwa;Kim, Hyung-Joong;Kim, Dong-Hwan;Hong, Dae-Byuk
    • Journal of The Korean Society of Agricultural Engineers
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    • v.53 no.6
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    • pp.85-91
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    • 2011
  • Three different types of wetlands (unplanted wetland, reed planted wetland, cattail planted wetland) were constructed at the mouth of Seokmoon reservoir with 910 $m^2$ each to examine the effects of wetland plant on pollutant removal rate in constructed wetland, and operated for 9 years (2002~2010). Water depth of the wetland was maintained at 0.3~0.5 m, flow rate was about 40~200 $m^3$/day, and retention time was managed at about 1~5 days. There was no difference in removal rate of SS, TN, and TP between reed wetland and cattail wetland. Removal rate of SS and TN in planted wetland with reed and cattail were higher than unplanted wetland, whereas removal rate of TP in unplanted wetland was higher then planted wetland. The monthly variation of removal rate in planted wetlands was high compared with unplanted wetland. From the long term monitoring results, SS and TN removal rates of period3 (2008~2010) were higher than period1 (2002~2004) in planted wetland, whereas TP removal rate was decreased as time goes on. Overall, pollutant removal rate in constructed wetland was more influenced by existence of plants than by plant species. Although constructed wetland is operated long term period, SS, TN, and TP removal rate (SS 90 %, TN 60 %, TP 40 %) can be maintained high values.

Analgesic Effect of Electroacupuncture on the Pain Induced by Electrical Stimulation (전기자극에 의해 유발된 통증에 대한 말초 전침자극의 진통효과)

  • Hwang, Joon-Ha
    • The Korean Journal of Physiology
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    • v.21 no.1
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    • pp.79-90
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    • 1987
  • The present experiment was performed in 35 normal male volunteers to evaluate the effect of electroacupuncture on the human nociception more clearly and to demonstrate the effect of different parameters of electrical stimulation through acupuncture needles. The threshold of the pain(Tp) and the nociceptive flexion reflex(Tr), the threshold for intolerable pain(Tip) and that for obtaining maximal reflex response(Tmr) were studied before and after electroacupuncture performed on the acupoints of tsusanli and hsuanchung. 1) For the pricking pain, electroacupuncture with intermittent stimulation induced a significant decrease in Tp which recovered after removal of the needles. There was no significant change in other thresholds. 2) For the dull pain, electroacupuncture with intermittent stimulation produced a significant increase in Tp which continued after removal of the needles. But there was no signifcant change in Tip. Electroacupuncture with continuous stimulation induced a slight increase in Tp. 3) After resting without electroacupuncture, Tp and Tip of the dull pain were slightly decreased. These results suggest that electroacupuncture had no significant analgesic effect on the pricking pain induced by electrical stimulation of the foot skin. However, electroacupuncture with intermittent stimulation had significant analgesic effect on the weak dull pain and it had slightly greater analgesic effect than electroacupuncture with continuous stimulation.

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Performance of Night Soil Treatment Plant using B3(Bio-Best-Bacillus) System (B3공법을 이용한 분뇨처리시설 처리효율에 관한 연구)

  • Seo, Yun-Ha;Lee, Jung-Bong;Choi, Sung-Yong;Kim, Deug-Ho;Kim, Jin-Hwan;Byeun, Jeung-Bok
    • Journal of Korean Society of Water and Wastewater
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    • v.24 no.4
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    • pp.407-412
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    • 2010
  • The purpose of this study was to investigate removal efficiencies of contaminants in night soil treatment plant using the B3 system. The samples were collected from retaining tank and settlement tank in Yechon night soil plant. We experimented concentrations of BOD, COD, SS, TN and TP. Concentration data were processed using removal efficiencies by season and correlation analysis with pilot running parameters. Removal efficiencies of total organic carbon was over 96%, TN was 98% during summer, 80.9% during winter. In the case of TP, the highest removal efficiencies was 94.1% during fall and the lowest removal efficiencies was 82% during spring. Results of correlation analysis showed two positive correlation groups and one negative group. Positive correlations were among temperature, BOD and TN. The others were pH, BOD, COD, SS, TN and TP. Negative correlation were among MLSS, BOD, COD, SS, TN, TP.

Estimation of Pollutants Residence Time During the Flood and Dry Season in Gwangyang Bay (광양만의 홍수기 및 갈수기의 오염물질 체류시간 산정)

  • Lee, In-Cheol;Kim, Jin-Hyuk;Kong, Hwa-Hun
    • Journal of Ocean Engineering and Technology
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    • v.22 no.6
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    • pp.20-26
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    • 2008
  • In this paper, in order to set up the management system of water quality environment in Gwangyang Bay, the cluster analysis of water quality environment, the estimation of inflowing pollutant loads and residence time of pollutants in this bay was carried out. The Gwangyang Bay was divided into eight sea areas by cluster analysis and spatio-temporal change of water quality. The river discharges in the Bay were calculated about $11,681{\times}103m^3/day$ from the numerical simulation by Tank model. In addition, inflowing pollutant loads of COD, SS, TN, TP, DIN and DIP in Gwangyang Bay were estimated at 398 ton-COD/day, 2,846 ton-SS/day, 195 ton-TN/day, 5 ton-TP/day, 126 ton-DIN/day and 3 ton-DIP/day, respectively. Moreover, residence times of COD, TN and TP in the Bay was estimated at 6 days-COD, 20 days-TN and 195 days-TP, respectively in the dry season, and 3 days-COD, 6 days-TN and 21 days- TP, respectively, in the flood season. The central part of Gwangyang Bay (Region IV) has the longest residence time of overall pollutants.

Immunopreventive Effects against Murine H22 Hepatocellular Carcinoma in vivo by a DNA Vaccine Targeting a Gastrin-Releasing Peptide

  • Meko'o, Jean Louis Didier;Xing, Yun;Zhang, Huiyong;Lu, Yong;Wu, Jie;Cao, Rongyue
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.9039-9043
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    • 2014
  • There is a continuing need for innovative alternative therapies for liver cancer. DNA vaccines for hormone/growth factor immune deprivation represent a feasible and attractive approach for cancer treatment. We reported a preventive effect of a DNA vaccine based on six copies of the B cell epitope GRP18-27 with optimized adjuvants against H22 hepatocarcinoma. Vaccination with pCR3.1-VS-HSP65-TP-GRP6-M2 (vaccine) elicited much higher level of anti-GRP antibodies and proved efficacious in preventing growth of transplanted hepatocarcinoma cells. The tumor size and weight were significantly lower (p<0.05) in the vaccine subgroup than in the control pCR3.1-VS-TP-HSP65-TP-GRP6, pCR3.1-VS-TP-HSP65-TP-M2 or saline subgroups. In addition, significant reduction of tumor-induced angiogenesis associated with intradermal tumors of H22 cells was observed. These potent effects may open ways towards the development of new immunotherapeutic approaches in the treatment of liver cancer.

Pro Variant of TP53 Arg72Pro Contributes to Gastric Cancer Risk in Asians: Evidence from a Meta-analysis

  • Su, Xiu-Li;Jin, Jian-Jun
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.3
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    • pp.915-921
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    • 2012
  • Background: Previous studies investigating the association between TP53 Arg72Pro polymorphism and gastric cancer (GC) risk in Asian population have reported controversial results. Thus, a meta-analysis was performed. Methods: A comprehensive literature search was conducted and 17 case-control studies were finally included, involving a total of 5,990 GC cases and 6,812 controls. Subgroup analyses were performed by the sample size. Results: Meta-analysis of all 17 studies showed variant genotypes of TP53 Arg72Pro to be associated with an elevated GC risk in three genetic comparison models ($OR_{Pro\;vs.\;Arg}$=1.13, 95%CI 1.03-1.25, $P_{OR}$=0.01; $OR_{Homozygote\;comparison\;model}$=1.33, 95%CI 1.07-1.64, $P_{OR}$=0.009; $OR_{Dominant\;genetic\;model}$=1.13, 95%CI 1.05-1.22, $P_{OR}$=0.002). Besides, a more obvious association was observed after the heterogeneity was decreased (all P values less than 0.001). This association was further identified by both subgroup and sensitivity analyses. Conclusions: This meta-analysis suggests the Pro variant of TP53 Arg72Pro contributes to gastric cancer risk in Asians.

Viscous Effects on the Characteristics of TP620 Hydrofoil (점성의 영향을 고려한 박용 TP620 익형의 익특성 연구)

  • 김시영
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.21 no.2
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    • pp.137-141
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    • 1985
  • In this paper, the author investigate viscous effects on the characteristics of TP620 hydrofoil. The pressure distribution on the foil section in non-cavitating flow should be considered its characteristics of displacement thickness due to viscous effects. Theoretical potential theory, which neglects viscous effects do not agree with this analysis, especially at leading edge region of the foil. And, the efficiency of TP620 hydrofoil considering viscous effects is a little lower than that of the foil, which neglected viscous effects.

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Charateristics of Wake Flow in a Flat Plate Blade Having TS and TP Cutting (평판익 후연의 형상에 따른 후류 특성)

  • Jang, Choon-Man;Ahmad, Imteyaz;Kim, Kwang-Yong
    • 유체기계공업학회:학술대회논문집
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    • 2004.12a
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    • pp.452-455
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    • 2004
  • The influence of wake flow on a flat-plate blade having different shapes near the hailing edge has been investigated in this paper. Two different shapes near the trailing edge namely the pressure surface cutting (TP) and the suction surface cutting (TS) have been used. The calculation has been performed for two different angles of attack (a =10 and 15 degree) in both the cases. RANS equations have been solved using SST-model as a turbulence closure. Cp and CL values obtained for TS are higher compared to those obtained for TP. Also, the vorticity distribution obtained in case of TS is stronger as compared to that obtained in the case of TP The Karmann Vortex is observed in both the cases but it is more clear in TS case. It is found that in the case of TS, flow separation does not occur upto the trailing edge on both the suction and the pressure sides of the blade while in the case of TP, the flow separateson the pressure surface near the trailing edge of the flat-plate blade.

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