• Mycobiology
• /
• v.42 no.3
• /
• pp.215-220
• /
• 2014

Mushrooms are a recognized component of the human diet, with versatile medicinal properties. Some mushrooms are popular worldwide for their nutritional and therapeutic properties. However, some species are dangerous because they cause toxicity. There are many reports explaining the medicinal and/or toxic effects of these fungal species. Cases of serious human poisoning generally caused by the improper identification of toxic mushroom species are reported every year. Different substances responsible for the fatal signs and symptoms of mushroom toxicity have been identified from various poisonous mushrooms. Toxicity studies of mushroom species have demonstrated that mushroom poisoning can cause adverse effects such as liver failure, bradycardia, chest pain, seizures, gastroenteritis, intestinal fibrosis, renal failure, erythromelalgia, and rhabdomyolysis. Correct categorization and better understanding are essential for the safe and healthy consumption of mushrooms as functional foods as well as for their medicinal use.

• Toxicological Research
• /
• v.2 no.2
• /
• pp.51-62
• /
• 1986

Of mushrooms found in Japan, approximately 35 species are classified as poisonous mushrooms. The mushroom poisonings caused by these mushrooms are classified as three types accodring to the symptoms and their toxic constitutents. The first type is the cholera-like symptom which is induced mainly by the toxic constitutents such as cyclopeptide and gyromitrin. The second type is the neurological mainfestations induced by muscarine (cholinergic), muscimol (delirium), psilocybin (hallucinogenic) and coprine (antabuse-like).

• Toxicological Research
• /
• v.4 no.2
• /
• pp.85-94
• /
• 1988

In order to elucidate the mechanism of toxic action of a pisonous mushroom, Amanita pantherina, biochemical effects of the mushroom extracts on mice were studied. A hotwater extract of Amanita pantherina injected intraperitoneally into male ICR mice evoked signs similar to those observed clinically upon acute poisoning by the mushroom and also changed the levels of component enzyme activities in blood, liver and urine. The serum cholinesterase activity was decreased significantly during 1-3 h after injection.

• Applied Biological Chemistry
• /
• v.37 no.5
• /
• pp.392-396
• /
• 1994

The toxic substance causing blown blotching on the mushroom cap was extracted and purified from the culture broth of P.tolaasii. Purification and identification of the toxic compound was carried out with the silica gel chromatography, mass spectrum and NMR and appeared to be an aminobenzene in amylamine group. The purified toxic substance showed UV spectrum at 234nm and melting point at $76^{\circ}C$, respectively.

• Toxicological Research
• /
• v.5 no.1
• /
• pp.1-7
• /
• 1989

Toxic effects of a mushroom, Amanita volvata, were studied in respect to biochemical and histological changes induced in the liver and kidneys of mice. The changes in biochemical parameters characteristically appeared 12 hrs after oral administration of an aqueous extract of the mushroom. The hepatic glycogen decreased markedly to 17% of the control level and a concemitant decrease in blood glucose was also observed. The activity of serum glutamic oxaloacetic transaminase (SGOT) was elevated by 2.5-fold and the level of blood urea nitrogen (BUN) increased by 3-fold, respectively, 12 hrs after administration of the mushroom, their levels being maintained up to 24 hrs.

• Journal of Animal Science and Technology
• /
• v.49 no.1
• /
• pp.67-78
• /
• 2007

This study was carried out to monitor feed-nutritional components, toxic heavy metals (Cd, Pb and As) and pesticide residues through three cultivation stages (1st initial culture stage, 2nd mycelial growth stage, and 3rd fruit body-harvested stage) of king oyster mushroom (Pleurotus eryngii) produced by bottle type cultivation and oyster mushroom (Pleurotus osteratus) produced by vinyl bag type cultivation. For both cultivation types, compared with the initial culture, the weight reduction rate in spent mushroom substrates (SMS) after fruit body harvest was 29% for total wet mass, 21～25% for dry and organic matters and 19 ～22% for neutral detergent fiber. Two thirds to 3/4 of organic matter degraded and utilized by mycelia and fruit bodies was originated from fiber, of which the primary source (50～70%) was hemicellulose. The effect of mycelial growth stage on chemical compositional change in culture was little (P>0.05) for bottle type cultivation of king oyster mushroom but considerable (P<0.05) for vinyl type cultivation of oyster mushroom. Culture nutrients uptake by fruit bodies was very active for the bottle type cultivation. Compared with SMS, harvested fruit bodies (mushrooms) contained higher (P<0.05) crude protein, non-fibrous carbohydrate, and crude ash and lower (P<0.05) neutral detergent fiber. Regardless of stages, no culture samples were contaminated with toxic heavy metals and pesticide residues. In conclusion, the increase of fiber (neutral and acid detergent fibers) and indigestible protein contents and the decrease of true protein content in SMS indicated that the feed-nutritional value of SMS was significantly reduced compared with that of the initial culture and they were safe from toxic heavy metals and pesticide residues.

• Plant Resources
• /
• v.4 no.3
• /
• pp.153-156
• /
• 2001

Today information is important for man and total fields. Science field is not exception. Currently information age things of information is only useful for man and total industry. So bioinformation is necessary of biodiversity in broadly wide and detailed information. Among information, bioinformation of biodiversity is important and utilization of living things. Among them, the mushroom(higher fungi) are an important part in ecosystem as a decomposer responsible for recycling materials. Many living things today, however, have endangered by environmental pollution and ecological destruction. The higher fungi also are not exception. Mushroom has been used for food sources, pharmacy and forests resources from ancient times. Among biodiversity, database of mushroom is very necessary for university, institute and industry. This DB contains four items of native mushroom(higher fungi) from Korea. first item contain species, genus, family, order class, ad division according to the classification. Second item contain pharmaceutical purpose, food source, culture, toxic, anti-cancer of the application. Third item contain symbiosis, rotten trees of the ecological resources. Fourth item contain geographical distribution and illustrated literature. Information system is also available using KRISTAL II for searches on the WEB in URL http://ruby. kisti. re. kr/∼mushroom.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2001.11a
• /
• pp.9-14
• /
• 2001

Today information is important for man and total fields. Science field is not exception. Currently information age things of information is only useful for man and total industry. So bioinformation is necessary of biodiversity in broadly wide and detailed information. Among information, bioinformation of biodiversity is important and utilization of living things. Among them, the mushroom(higher fungi) are an Important part in ecosystem as a decomposer responsible for recycling materials . Many living things today, however, have endangered by environmental pollution and ecological destruction. The higher fungi also are not exception. Mushroom has been used for food sources, pharmacy and forests resources from ancient times. Among biodiversity, database of mushroom is very necessary for university, institute and industry. This DB contains four items of native mushroom(higher fungi) from Korea. first item contain species, genus, family, order class, ad division according to the classification. Second item contain pharmaceutical purpose, food source, culture, toxic, anti-cancer of the application. Third item contain symbiosis, rotten trees of the ecological resources. Fourth item contain geographical distribution and illustrated literature. Information system is also available using KRISTAL II for searches on the WEB in URL http://ruby. kisti. re. kr/～mushroom

• Advances in Traditional Medicine
• /
• v.4 no.1
• /
• pp.22-27
• /
• 2004

Cisplatin is a highly effective and extensively used anticancer drug. Higher doses of cisplatin manifest acute nephrotoxicity and this is one of the limiting factors of this drug in cancer chemotherapy. The effect of the oyster mushroom extract to ameliorate cisplatin ( cis platinum (II) diammine dichloride) induced nephrotoxicity and restoration of antioxidant defence system in mice was investigated. The investigations showed that prior administration of methanolic extract of Pleurotus florida at a dose of 500 and 1000mg/Kg body weight significantly reduced elevated serum creatinine and urea levels and increased superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities in the kidney, consequent to cisplatin treatment, in a dose dependent manner. The extract restored the decreased reduced glutathione (GSH) activity and increased malondialdehyde (MDA) level due to cisplatin administration. The results thus indicated that oyster mushroom extract rendered significant protection against cisplatin induced nephrotoxicity and depletion of antioxidant defence system in a dose dependent manner. Since oyster mushrooms are excellently edible and non-toxic, the finding reported here is of significant use in cancer chemotherapy.

• Journal of The Korean Society of Clinical Toxicology
• /
• v.2 no.2
• /
• pp.133-136
• /
• 2004

Phalloides syndrome has usually occurred after incidental mushroom ingestion. It is sometimes difficult to differentiate toxic mushrooms from edible ones, especially in lay person because of their morphological similarities. In Korea, Amanita virosa and Amanita subjunquillea have been reported as a cause of fulminant hepatic failure in mushroom poisoning (phalloides syndrome). We report a case of phalloides syndrome who came to death with fulminant hepatic failure even though we planned liver transplantation and used T-PLS(R) (Twin Pulse Life Support) for hemodynamic support while waiting for the donor.