• Title/Summary/Keyword: Total particulate matter

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Comparative Study of Particulate Contamination from Ampoule and Prefilled Syringe (앰플 및 1회용 주사용기에서의 미립자 혼입에 관한 비교연구)

  • Shim, Chang-Koo;Han, Yong-Hae;Kwon, Don-Sun
    • Journal of Pharmaceutical Investigation
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    • v.21 no.3
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    • pp.155-160
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    • 1991
  • Particulate is the foreign insoluble material in injectable solution inadvertently present in a given product. Considerable efforts have been made to avoid or minimize particulate contamination by pharmaceutical manufacturers during the production of parenteral products. Particulate contamination of the parenteral products can occur mainly during the opening (cutting) the container immediately before clinical use. In this study, particulate contamination generated during the opening process of ampoules (conventional type, 1-point and color-break ampoules) was compared with that of a prefilled injectable container (prefilled syringe). The particles were examined under a microscope after filtration of the total fluids in the containers. Particles having wide range of size distribution were found from all the ampoules tested. The contamination from the I-point ampoule and colorbreak ampoule was much less than from the conventional ampoule. Glass particles generated by cutting the glass-made ampoules seemed a principal source of the particulate contamination. The glass-partiaulte contamination could be improved substantially by replacing the ampoule containers with the prefilled syringe. Prefilled syringe, which can be used without any cutting process. did not generate particulates during the use. Therefore, it was concluded that prefilled syringe is most preferable container for the small volume parenteral (SVP) fluids in terms of particulate contamination.

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A Statistical Assessment of Particulate Exposure Concentration for the Welders and Grinding workers (입자상 물질 폭로농도의 통계적 평가방법에 관한 고찰 -용접·연삭 작업장의 근로자를 대상으로-)

  • Yoon, Young-No;Yi, Kwan-Hyeong
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.1 no.2
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    • pp.154-163
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    • 1991
  • Particulate matter exposure leva1 of welders and grinding workers was evaluated in Banwol and Changwon industry complexes. Full period single sample and full period consecutive samples were collected with personal air samplers attached to workers. Compliance difference with 8-hour time weighted average (TWA) was compared by Korean strategy and the classification system recommended by OHSA for employee exposure to particulates. And difference of compliance was compared according to precision of measurement and analysis (total precision). Compliance rate was depended on the total precision, therefore, quality control of measurement and analysis was important.

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Chemical Properties and Source Profiles of Particulate Matter Collected on an Underground Subway Platform

  • Ma, Chang-Jin;Lee, Kyoung-Bin;Kim, Shin-Do;Sera, Koichiro
    • Asian Journal of Atmospheric Environment
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    • v.9 no.2
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    • pp.165-172
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    • 2015
  • Under a very tough situation that there has been increasing concern to the air quality in underground subway spaces, this study set sights on the thorough estimation of the chemical properties and source apportionment of particulate matter (PM) collected on an underground subway platform by a cooperative approach of semi-bulk and single particle analyses. The size-resolved PMs were intensively collected on the platform of Miasageori station on the Seoul Subway Line-4, and then, they were semibulkily analyzed by a PIXE and the TOR$^{(R)}$ method, and individually analyzed by a SEM-EDX. Overwhelmingly enriched iron was a notable feature of elemental concentration of $PM_{2.5}$. Source classification of iron in $PM_{10-2.5}$ and $PM_{2.5}$ performed along with their elemental concentrations, indicates that the railway originated iron accounts for 95.71% and 66.39% of total iron in $PM_{10-2.5}$ and $PM_{2.5}$, respectively. Via a stoichiometric categorization, $Fe_2O_3$, $CaAl_2Si_2O_8$, $Al_2O_3$, and $CaCO_3$ show more than 85% abundance ratio in individual coarse particles. The result of theoretical estimation of the subway derived organic carbon ($OC_{Subway}$) suggests that $OC_{Subway}$ in $PM_1$ and $PM_{2.5-1}$ account for 75.86% and 51.88% of total organic carbon, respectively.

Evaluation of the microbiome composition in particulate matter inside and outside of pig houses

  • Hong, Se-Woon;Park, Jinseon;Jeong, Hanna;Kim, Minseok
    • Journal of Animal Science and Technology
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    • v.63 no.3
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    • pp.640-650
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    • 2021
  • Particulate matter (PM) produced in pig houses may contain microbes which can spread by airborne transmission, and PM and microbes in PM adversely affect human and animal health. To investigate the microbiome in PM from pig houses, nine PM samples were collected in summer 2020 inside and outside of pig houses located in Jangseong-gun, Jeollanam-do Province, Korea, comprising three PM samples from within a nursery pig house (I-NPH), three samples from within a finishing pig house (I-FPH), and three samples from outside of the pig houses (O-PH). Microbiomes were analyzed using 16S rRNA gene amplicon sequencing. Firmicutes was the most dominant phylum and accounted for 64.8%-97.5% of total sequences in all the samples, followed by Proteobacteria (1.4%-21.8%) and Bacteroidetes (0.3%-13.7%). In total, 31 genera were represented by > 0.3% of all sequences, and only Lactobacillus, Turicibacter, and Aerococcus differed significantly among the three PM sample types. All three genera were more abundant in the I-FPH samples than in the O-PH samples. Alpha diversity indices did not differ significantly among the three PM types, and a principal coordinate analysis suggested that overall microbial communities were similar across PM types. The concentration of PM did not significantly differ among the three PM types, and no significant correlation of PM concentration with the abundance of any potential pathogen was observed. The present study demonstrates that microbial composition in PM inside and outside of pig houses is similar, indicating that most microbe-containing PM inside pig houses leaks to the outside from where it, along with microbe-containing PM on the outside, may re-enter the pig houses. Our results may provide useful insights regarding strategies to mitigate potential risk associated with pig farming PM and pathogens in PM.

Considerations on the Temperature Distributions and Gradients in the Filter During Regeneration in Burner Type Diesel Particulate Trap System (버너방식 DPF 시스템의 재생과정 중 발생하는 내부 온도분포 및 온도구 배에 관한 고찰)

  • 박동선;김재업;김응서
    • Transactions of the Korean Society of Automotive Engineers
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    • v.4 no.6
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    • pp.78-84
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    • 1996
  • In order to eliminate TPM(Total Particulate Matter) from a diesel engine, we designed and developed a particulate trap system using a burner, which was named as AEFR(Active Exhaust Feeding Regeneration) system. We have considered the temperature distributions and gradients in the filter being regenerated according to regeneration control schemes Ⅰ, Ⅱ and Ⅲ. Schemes Ⅲ has shown the most desirable peak temperature and temperature gradients in AFER system. Finally, it was concluded that much lower peak temperature and temperature gradients in the filter could be obtained than that of other advanced research results by our AEFR system.

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밀폐된 공간에서 환기에 의한 ETS 성분 제거

  • 황건중;이문수;나도영
    • Journal of the Korean Society of Tobacco Science
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    • v.21 no.1
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    • pp.102-108
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    • 1999
  • This study was conducted to evaluate the ventilation to remove gases, vapor and particles of environmental tobacco smoke(ETS) in a closed room. The ventilation rate choosed were 0.445 ㎥/min, 0.528 ㎥/min, and 0.625 ㎥/min. ETS components measured were total suspended particle(TSP), ultraviolet particulate matter(UVPM), fluorescent particulate matter(FPM), solanesol, carbon dioxide($CO_2$), carbon monoxide(CO), nicotine, and 3-ethenylpyri-dine(3-EP). The concentration of ETS components measured rapidly decreased as increasing ventilation rate, but the removal efficiency by ventilation was different from each ETS compounds. The $CO_2$, and CO, gaseous components of ETS, were dominant components to be removed from the room by ventilation. The ventilation with 0.528 ㎥/min for 1 hr was enough to remove over 99% of those gaseous components. Nicotine and 3-EP needed the ventilation for 2 hrs to reduce over 95 % of those components. As the same ventilation rate, 99 % of TSP and solanesol concentration were removed from the room within 2 hrs, UVPM and FPM concentration decreased 90 %.

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Analysis of Growth Indicators of Applied Plants by AHU(Air Handling Unit)-linking with Artificial Soil-based Vegetation Bio-filters (인공토양기반 식생바이오필터의 AHU(Air Handling Unit) 연계를 통한 적용식물의 생육지표 분석)

  • Kim, Tae-Han;Lee, So-Dam;An, Byung-Ryul
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.21 no.3
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    • pp.99-110
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    • 2018
  • Compared to yellow dust coming from China or particulate matter created naturally in spring due to Total Suspended Particulate(TSP), particulate matter in winter season have much more serious effect on human body as they penetrate cell membranes. Although such particulate matter are becoming a social issue, there are no concrete plans on how to reduce them. Air-purifying plants are limited in maintaining the indoor air quality of large area because it is usually difficult to quantify their performance. In order to improve this, a bio-filter that can be connected to air conditioner is suggested as an option. This study seeks to improve air conditioning model-based monitoring method for bio-filters from prior studies and objectify correlations between applied vegetation and growing environment into quantitative indicators. By doing so, this study seeks to provide criteria on plants applied to artificial soil-based vegetation bio-filters and basic information to set air-conditioning features. The study results confirmed significant tendency on the growing stability of each purifying plant in mechanical air-conditioning environment. Among three models selected for bio-filter vegetation models, epipremnum aureum showed high performance in quantitative indicators, including soil moisture, EC, and leaf temperature, etc., indicating that it would assure the highest growing stability in this test air-conditioning environment.

Multielement Analysis in Airborne Particulate Matter $(PM_{10})$ by INAA, ICP and AAS (INAA.ICP.AAS를 이용한 대기먼지 $(PM_{10})$의 다원소분석)

  • 정용삼;문종화;정영주;박광원;이길용;윤윤열;심상권;조경행;한명섭
    • Journal of Korean Society for Atmospheric Environment
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    • v.15 no.4
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    • pp.495-503
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    • 1999
  • Airborne particulate matter $(PM_{10})$ collected using high volume air sampler and silica fiber filter were analyzed by Instrumental Neutron Activation Analysis(INAA), Inductively Coupled Plasma Atomic Emission Spectrometry(ICP-AES) and Atomic Absorption Spectrometry(AAS), and the results were compared with each other. 30~40 trace elements in environmental standard reference materials(NIST SRM 1648 and NIES CRM No.8) were analyzed for the analytical quality control. The relative error for two-third of elements detected was less than 10%, and the standard deviation was less than 15%. During the sampling period for 24 hours, the mass concentration of total suspended particulate was 36.1$\mu\textrm{g}$/㎥ and the value is lower than the critical level in Korea. In the results of NAA, the elements of Al, As, Ba, Fe, La, Mg, Na, Sb, Zn were well agreed with those of other methods. In statistical estimation between different methods, the deviation of Al, Ba, Cr, Fe was less than 10% and quite reliable.

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OXIDATION CHARACTERISTICS OF PARTICULATE MATTER ON DIESEL WARM-UP CATALYTIC CONVERTER

  • Choi, B.C.;Yoon, Y.B.;Kang, H.Y.;Lim, M.T.
    • International Journal of Automotive Technology
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    • v.7 no.5
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    • pp.527-534
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    • 2006
  • Modern passenger cars with diesel engines are equipped with DOC(diesel oxidation catalyst) for the purpose of reducing HC and CO in the exhaust stream. Cold start exhaust emissions pose troubles here as on gasoline engine vehicles. As a result, some of the diesel passenger cars roll off todays the assembly lines with WCC(warm-up catalytic converter). Oxidation characteristics of the particulates in WCC is analyzed in this study by EEPS(engine exhaust particulate size spectrometer). The maximum number of PM is found to come out of WCC in sizes near 10nm when an HSDI diesel engine is operated under the conditions of high speed and medium to heavy load. When the temperature of the WCC exceeds $300^{\circ}C$, the number of PM smaller than 30 nm in diameter sharply increases upon passing through the WCC. Total mass of emitted PM gets reduced downstream of the WCC under low speed and light load conditions due to adsorption of PM onto the catalyst. Under conditions of high speed and medium to heavy load, the relatively large PM shrink or break into fine particles during oxidation process within the WCC, which results in more mass fraction of fine particles downstream of the WCC.

Carotenoid Pigments from Suspended and Sinking Particulate Matter in Prydz Bay, Antarctica

  • Noh, Il
    • Journal of Environmental Science International
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    • v.20 no.11
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    • pp.1357-1371
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    • 2011
  • Suspended and sinking particles were collected during ODP Leg 119 to the Indian Ocean sector of the Antarctic Ocean. Field work was carried out at four sampling sites in Prydz Bay. Two of these sites were located in the Outer Bay, and two in the Inner Bay. At the four locations, a total of ten deployments of a sediment trap array were made. The concentrations of carotenoids both in suspended and sinking particulate matter in Prydz Bay were analyzed using HPLC. Fucoxanthin was the dominant carotenoid pigments both in suspended and sinking particles. The present study also indicates that 19'-hexanoyoxyfucoxanthin-containing prymesiophytes (Phaeocystis spp.) was abundant in the study area. The flux rates of carotenoids were generally highest at 50 m, and approximately double the flux rates at deeper horizons, however, at Inner Bay sites, the mean flux rates of carotenoids were greatest at 200 m, and 3 times greater than that of 50 m. Such anomalous high fluxes at 200 m imply that grazers were locally abundant between 100 m and 200 m at these sites close to land, and this hypothesis is supported by visual evidence of lots of fecal pellets in the 200 m trap. Integrates standing stocks versus sinking pigments data support that particulate material in Prydz Bay was not recycled rapidly.