• 제목/요약/키워드: Total Utility

검색결과 535건 처리시간 0.024초

Comparison of the Walz Nomogram and Presence of Secondary Circulating Prostate Cells for Predicting Early Biochemical Failure after Radical Prostatectomy for Prostate Cancer in Chilean Men

  • Murray, Nigel P;Reyes, Eduardo;Orellana, Nelson;Fuentealba, Cynthia;Jacob, Omar
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권16호
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    • pp.7123-7127
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    • 2015
  • Purpose: To determine the utility of secondary circulating prostate cells for predicting early biochemical failure after radical prostatectomy for prostate cancer and compare the results with the Walz nomagram. Materials and Methods: A single centre, prospective study of men with prostate cancer treated with radical prostatectomy between 2004 and 2014 was conducted, with registration of clinical-pathological details, total serum PSA pre-surgery, Gleason score, extracapsular extension, positive surgical margins, infiltration of lymph nodes, seminal vesicles and pathological stage. Secondary circulating prostate cells were obtained using differential gel centrifugation and assessed using standard immunocytochemistry with anti-PSA. Biochemical failure was defined as a PSA >0.2ng/ml, predictive values werecalculated using the Walz nomagram and CPC detection. Results: A total of 326 men participated, with a median follow up of 5 years; 64 had biochemical failure within two years. Extracapsular extension, positive surgical margins, pathological stage, Gleason score ${\geq}8$, infiltration of seminal vesicles and lymph nodes were all associated with higher risk of biochemical failure. The discriminative value for the nomogram and circulating prostate cells was high (AUC >0.80), predictive values were higher for circulating prostate cell detection, with a negative predictive value of 99%, sensitivity of 96% and specificity of 75%. Conclusions: The nomagram had good predictive power to identify men with a high risk of biochemical failure within two years. The presence of circulating prostate cells had the same predictive power, with a higher sensitivity and negative predictive value. The presence of secondary circulating prostate cells identifies a group of men with a high risk of early biochemical failure. Those negative for secondary CPCs have a very low risk of early biochemical failure.

Investigation on Regional Distribution of Potential Energy Production with Agricultural By-Products in Agricultural Sector

  • Park, Woo-Kyun;Lee, Sun-Il;Shin, Joung-Du;Kim, Gun-Yeob;Kim, Yi-Hyun;So, Kyu-Ho
    • 한국토양비료학회지
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    • 제46권5호
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    • pp.343-350
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    • 2013
  • The objectives of this study were to estimate the potential biomass yield by using the biomass conversion index and evaluate the potential energy production by using the energy conversion index of biomass. Estimating the total biomass yield in Korea showed 9,646.3 thousand tons produced in 2012. Subsequent evaluation of the potential energy production using the estimated biomass yield in 2012 indicated that the calorific values were varied from 3,800 to 4,500 kcal $kg^{-1}$ for crop- and from 4,100 to 4,300 kcal $kg^{-1}$ for woody-based biomass, respectively. Among the examined biomass materials, the pruned branch of a nut tree appeared to be the greatest in bio-energy production showing 6,300 kcal $kg^{-1}$ in calorific value. Total potential energy production from agricultural by-products was estimated approximately at 3,966,000 TOE. Among the agricultural by-products examined, rice straw showed the greatest energy production potential being at 2,321,000 TOE. Furthermore, it might contribute to establishing the countermeasures of biomass utility in agricultural sector based on regional distribution chart of the potential biomass and energy yields in Korea.

필 댐의 특성을 고려한 농업용 저수지 정밀안전진단체계 개선 연구 (A Study on the Safety Inspection System Improvement of Agricultural Reservoir Considering Fill-Dam Characteristics)

  • 이창범;정남수;박승기;전상옥
    • 한국농공학회논문집
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    • 제58권4호
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    • pp.1-8
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    • 2016
  • In 2008, 17, 596 dams and reservoirs are scattered across South Korea, and 17, 505 of them (99.5 %) are used for agriculture and 99.3 % are fill dam types. This study aimed to review literature related to the precise safety diagnosis system for agricultural reservoirs established by Korea Rural Community Corporation (KRCC) and analyze problems of its evaluation method. And then, it proposed ways to improve the system including a modified diagnosis system, which was applied to pilot districts in order to verify the utility. For assessment model development of agricultural reservoir, we reviewed status of precision safety inspections systems of agricultural reservoir. There are many problems such as assess agricultural reservoir not by sheet which used in fill dam but by block which used in concrete dam construction and diversion tunnel which main element in reservoir levee is treated as water intake facility. For considering diversion tunnel in reservoir levee, previous precision safety inspection systems which summed in separated phenomenon, separated element, separated site, separated facility was change to new systems which summed in site, phenomenon, element, and facility. Compared results of previous inspection system calculated total assessment index (Ec) with new system calculated total assessment index (Ec) are not show statistical difference.

4가지 온대성 지피식물의 실내 포름알데이드 제거효과 (The Effect of the Formaldehyde Removal of Fore Temperate Ground Cover Plants)

  • 주진희;방광자;이진희
    • 한국조경학회지
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    • 제35권2호통권121호
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    • pp.49-54
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    • 2007
  • This research was performed to investigate the effect of formaldehyde removal and confirm the utility of plants as indoor environment improvement systems. The plant materials used in this study were Fatsia japonica, Ardisia japonica, Ardisia pusilla and Davallia mariesii. Plants were placed in an airtight chamber under artificial formaldehyde. The initial formaldehyde concentration in the chamber was $500{\pm}30ppb$, and the conditions of $1,500{\sim}2,000lux$ light, $25{\pm}5^{\circ}C$ temperature and $80{\sim}90%$ humidity were maintained. Each chamber was treated as no plant, plant-only and Plant+soil. The total leaf number for Davallia mariesii, Ardisia japonica, Ardisia pusilla, and Fatsia japonica was 40.8, 48.6, 62.3, and 11.8 respectively. The total leaf space n of those plant materials were $2,385cm^2,\;1,252cm^2,\;2,468cm^2\;and\;1,262cm^2$ respectively. The formaldehyde concentration was reduced to $80{\sim}90%$ of the initial concentration in plant-only and Plant+Soil treatment chamber of all species in 12 hours. In the plant-only chamber, Fatsia japonica had removed formaldehyde density by 95% after 12 hours while Ardisia japonica had removed 90%. In the case of Ardisia pusilla, the early removal rate was higher in the plant-only treatment chamber than the Plant+Soil treatment chamber. The formaldehyde removal rate of Davallia mariesii was 98% after 12 hours. In the Plant+Soil treatment chamber, the amount of removal of formaldehyde per time of Davallia mariesii, Ardisia japonica, Ardisia pusilla, and Fatsia japonica was 20.42ppb/hr, 16.28ppb/hr, 2.5.42ppb/hr, 10.28ppb/hr respectively. In the plant-only, That was 22.50ppb/hr, 20.97ppb/hr, 20.83ppb/hr, 20.97ppb/hr respectively.

Development of EST-SSR markers for genetic diversity analysis in little millet (Panicum sumatrense) genetic resources

  • Lee, Myung-Chul;Choi, Yu-Mi;Lee, Sukyeung;Yoon, Hyemyeong;Oh, Sejong
    • 한국자원식물학회:학술대회논문집
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    • 한국자원식물학회 2018년도 추계학술대회
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    • pp.74-74
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    • 2018
  • Little millet (Panicum sumatrense) is well known for its salt and drought stress tolerance and high nutritional value, but very limited knowledge of genetic variation and genomic information is available. This study was to develop highly polymorphic EST-SSR markers based on cross-species transferability of derived SSRs from switchgrass EST databases and characterize newly developed EST - SSRs to better understand the genetic diversity of collected 37 germplasm accessions of little millet. A total of 779 primer pairs were designed from the 22,961 EST sequences of switchgrass (Pancium virgatum), of which 48 EST - SSR markers were developed based on the trials of transferability of these primers in little millet. The EST - SSR amplicons showed reproducible single band polymorphism and produced a total of 160 alleles with an average of 3.3 alleles per locus in 37 accessions of little millet. T he average values of expected and observed heterozygosities were 0.266 and 0.123, respectively. T he polymorphic information content (PIC) values were observed in range of 0.026 to 0.549 with an average of 0.240. The genetic relatedness among the little millet accessions was evaluated by neighbor-joining dendrogram, which grouped all accessions into two distinct groups. The validation thus demonstrated the utility of the switchgrass EST - SSR markers in assessing genomic relationships in little millet. T he findings from this study could be useful for designing strategies for the identification of diverse germplasm for conservation and future molecular breeding programs for little millet.

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이종 네트워크 하향링크의 셀간 간섭 조정 및 사용자 스케줄링을 위한 저복잡도 알고리즘 (A Low-Complexity Algorithm for Inter-Cell Interference Coordination and User Scheduling in Downlink Heterogeneous Networks)

  • 박진현;이재홍
    • 전자공학회논문지
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    • 제51권6호
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    • pp.9-17
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    • 2014
  • 이종 네트워크(HetNet)란 매크로셀 내에 소형셀이 혼재한 네트워크이다. 이종 네트워크에서는 대형셀로부터 소형셀 사용자에게 미치는 간섭이 소형셀 사용자의 성능을 열화시키는 주 원인 중 하나이며, 이 간섭을 줄이기 위해 향상된 셀간 간섭 조정기법(eICIC)이 필요하다. 기존의 eICIC 관련 연구에서는 프레임별 채널 변화를 거의 고려하지 않고 네트워크의 장기 처리율을 최대화하는 데 치중되어 성능 향상이 제한적이었다. 이 논문에서는 네트워크 전체 효용을 최대화하기 위해 매 프레임마다 동적으로 셀간 간섭을 제어하고 사용자를 스케줄링하며, 전수검색보다 계산 복잡도가 낮은 새로운 알고리즘을 제안한다. 제안된 알고리즘이 기존 알고리즘보다 네트워크 전체 처리율을 향상시키며, 사용자의 수가 많을 때 사용자간 공평성을 향상시킴을 컴퓨터 모의실험을 통해 보인다.

방사 면역측정법에 의한 혈청내 갑상선 유리홀몬 측정의 임상적의의에 대한 기본적 검토 (An Assessment of Measurement of Serum Free $T_3,\;T_4$ by Radioimmunoassay)

  • 김영훈;이형호;안희권;김숙주;김준석;안일민;이창홍;박승철
    • 대한핵의학회지
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    • 제19권1호
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    • pp.113-117
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    • 1985
  • The present study was undertaken to examine serum concentration of free $T_3,\;T_4$, in various functional states of the thyroid by Amerlex RIA kit method, which uses unidentified $T_3,\;T_4-labelled$ analogues, said to be unreactive with $T_3,\;T_4-binding$ proteins in serum, together with an antibody that binds both analogue and $T_3,\;T_4$. The test method has been compared with free $T_4$ index, which was product of total serum thyroxine and $T_3$ resin uptake ratio. Free $T_4$ value by this method was found to have a highly significant positive correlation with a free $T_4$ index (r; 0.957, p<0.005) and total $T_4$ (r:0.89, p<0.005) also, it was similar to other free $T_4$ measuring methods previously reported. So, it was showen to have the clinical utility as the screening test for thyroid function because it was a rapid; convinient, and reliable method for quantifying the free $T_4,\;T_3$ concentration in various thyroidal functional states.

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섭식행동의 세가지측면 : 의식적 식이제한, 탈억제, 배고픔의 정도를 사정하기 위한 도구개발연구 (The Three Dimentions of Eating Behavior : Development of scale for assessing cognitive restraint of eating, disinhibition, and hunger)

  • 김문실;김숙영
    • 대한간호학회지
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    • 제27권2호
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    • pp.377-388
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    • 1997
  • This study was done to develop a eating behavior scale for high school girls using Stunkard and Messick(1985)'s three factors(dietary restraint disinhibition, hunger) as a conceptual framework and to test the validity and reliability of the scale. The subjects were 202 high school girls. The convenience sample is consist of 96 normal weight and 106 obese girls. Data were collected between October 28 and November 25 in 1996 and analyzed using the SPSS package. The new 32-item scale measuring these factors is presented 1. Three stable factors emerged and these contributed 45.7% of the variance in the total score. All 32 items loaded above .35 on each factor, 2. Factor 1 was named disinhibition(14 items), factor 2 was named cognitive restraint of eating(10 items), factor 3 was named hunger(8 items). Comparison of factor Ⅰ, factor Ⅱ, factor Ⅲ between normal subjects and obese subjects showed that there was a significant difference in factor Ⅱ & Ⅲ, not in factor Ⅰ. 3. Cronbach's alpha coefficient for internal consistancy was .9393 for total 32 items and .8820, .8652, .8490 for three dimensions of eating behavior in high school girls. Recommendations are suggested below : 1. Replication study with appropriate age groups be done to test validity and reliability, 2. The present developed scale must be a reliable measure of eating behavior and should have utility in further study on how effective nursing intervention related to different kind of groups such as disinhibition group and cognitive restraint of eating group. 3. To extend validity of the scale, further study is needs using more larger subjects which is consists of dieters and free eaters.

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어린이 급식소 위생·안전관리 수행 도구 개발 (Developing A Tool to Execute Children's Food Service Hygiene and Safety Management)

  • 이진용
    • 한국식품영양학회지
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    • 제29권2호
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    • pp.253-266
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    • 2016
  • The current study was conducted to facilitate appropriate hygiene and safety management in children's food service stations, with the ultimate objective of providing sanitary and safe food service to children. In order to develop questionnaire items, literature review was conducted, in addition to detailed interview of working-level personnel at a children's food service management support center. This resulted in a total of thirty questions on personal hygiene management, food materials hygiene management, and facilities hygiene management. Using the questionnaire, seventy-one food service stations for children in District A in Seoul that serve less than one hundred children were surveyed to analyze the reliability, construct validity, and correlation in the developed measurement tool. The developed measurement tool consisted of ten task and environmental hygiene management questions, five personal and cooking hygiene management questions, four food ingredient and storage hygiene management questions, and four food service operation and management question; with a total of twenty-three questions, in four factors stated above. The cumulative distribution of the four factors was 54.698%, and Cronbach's ${\alpha}$ value was 0.672~0.853, which indicated that the study was reliable. The results of the analysis indicated that each of the factors were correlated, the study was satisfactory, and the tool was valid for evaluating hygiene and safety management practices in children's food service stations. Finally, in order to enhance practical utility of the developed measurement tool, the significance and limitations were described.

국내 인터넷 상의 보육시설 영유아 건강관련 웹사이트의 평가 (Evaluation of Internet Web-sites Providing Infant Health Related Information for Daycare Staffs)

  • 김지수
    • 한국콘텐츠학회논문지
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    • 제10권1호
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    • pp.334-342
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    • 2010
  • 본 연구의 목적은 보육시설 영유아 건강에 관련한 웹사이트를 평가함으로서, 영유아 건강정보가 타당하고 신뢰성 있는가를 분석하는 것이다. 총87개의 관련 사이트를 검색하고, 기존의 도구를 본 연구 목적에 맞게 수정 보완하여 평가한 결과, 32점 만점에 11~29점의 분포를 나타내 전반적으로 낮게 평가되었다. 정확성과 권위성이 가장 낮았고 내용성, 지속성 등도 약 절반가량의 사이트에서만 충족하고 있었다. 이러한 결과로 볼 때 영유아 건강정보를 제공하고 있는 사이트는 내용의 정확성이 매우 부족할 뿐 아니라 영유아 건강관리에 대한 전문성도 매우 미흡한 것으로 보인다. 특히 건강전문가가 없이 영유아를 집단으로 돌보는 보육시설에서는 이러한 건강정보를 이용하기가 한계가 있을 것으로 판단된다. 따라서 보육시설 영유아의 건강관리를 지원하기 위해서는 전문적 건강정보제공이 시급하다. 본 연구 결과는 영유아 건강관리를 지원하기 위한 프로그램 개발에 유용한 기초자료가 될 것으로 사료된다.