• Journal of Biomedical Engineering Research
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• v.35 no.6
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• pp.177-184
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• 2014

Continuous monitoring of heart rates and respiratory rates for newborns or infants is very important since the abnormal breathing and heart problems can threaten the life of newborns or infants. A noncontact baby monitoring system based on a Doppler radar and an air mattress was designed. The Doppler radar was used to acquire respiratory signals and the air mattress was employed to obtain heart rates. The performance of the designed system was evaluated using a commercialized infant simulator ($Simbaby^{TM}$) and a respiration belt transducer was used to measure respiration rates as a reference. Results for respiratory rates revealed that the correlation coefficients between I-and Q-channel and the respiration belt were 0.84 and 0.91 and the mean ${\pm}$ standard deviations of errors between them were $1.66{\pm}1.92$ (bpm) and $0.88{\pm}1.65$ (bpm). Heart rates showed that the correlation coefficient between air mattress and set value of the simulator was 0.73 and the mean ${\pm}$ standard deviation of errors between them was $1.09{\pm}3.45$ (bpm). These results indicate that the designed system holds the potential as an effective monitoring tool for continuous monitoring heart rates and respiratory rates of newborns or infants.

• The Journal of the Korea Contents Association
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• v.17 no.11
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• pp.541-553
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• 2017

Maker education rooted on Maker Movement refers to constructivist learning approach in which students as makers participate in producing visible outcomes through self-directed inquiry and creative hands-on activities in a real life context to solve their personal or social problems. The Maker education, therefore, stresses cultivation of 'maker mindset' in the process-oriented learning environments, pursuing evaluation aspects different from those in the existing educational system. In this context, this study aimed to explore an evaluation framework for the Maker education which reflects the Maker mindset: First, a literature review was conducted to search for the evaluation framework of the maker education which consists of the category of 5 ONs (Minds-on, Hands-on, Hearts-on, Social-on, Acts-on) representing intellectual, physical, emotional, interpersonal and practical aspects, respectively; Second, a Delphi survey for content validity was carried out to confirm the adequacy of the 5 ONs category along with sub-elements for each category. Finally, this study presented the evaluation framework for the Maker education, which is expected to be used as feedback rather than a measuring tool for the process and environments of the Maker education.

• The Journal of Korean Orthopaedic Ultrasound Society
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• v.8 no.1
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• pp.26-30
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• 2015

There are many traumatic foot and ankle problems in orthopaedic fields. Though it is not life-threatening problems, a delay in accurate diagnosis and treatments can danger limb function and therefore correct diagnosis can prevent long-term complications. Achilles tendon rupture is relatively common injury for active sports people. Ultrasonography is cost-effective, irradiation -free, effective for evaluation of soft tissues and dynamic analysis. It has been growing importance in Achilles tendon rupture. Ultrasonography is a diagnostic tool in Achilles tendon rupture. Physical examination and patient history is needed to diagnose Achilles tendon without image, but it is missed up by 20% in private clinic. Discontinuity of normal fibrillar architecture seen on an ultrasonographic image is diagnostic for Achilles tendon rupture, and can be accentuated by the performance of dorsi-flexion and plantar flexion, while observing in real time. And ultrasonography is a reliable method for serial observation after surgical treatment or conservative treatment.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.12
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• pp.4795-4800
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• 2014

Background: Few studies have directly compared clinical efficacy and safety among Chinese herb injections (CHIs) for gastric cancer (GC). The present study aimed to compare CHIs combined with FOLFOX regimens for GC to show which provides the best CHIs results. Materials and Methods: 9 electronic databases and 6 gray literature databases were comprehensive searched in April 20, 2013. According to inclusion and exclusion criteria, two reviewers independently selected and assessed the included trials. The risk of bias tool described in the Cochrane Handbook version 5.1.0 and CONSORT statement were used to assess the quality of the trials. All calculations and graphs were performed and produced using ADDIS 1.16.5 software. Results: A total of 541 records were searched and 38 RCTs met the inclusion criteria (2,761 participants), involving 10 CHIs. The results of network meta-analysis showed that compared with FOLFOX alone, combinations with Kanglaite, Astragalus polysaccharides, Cinobufacini, or Yadanziyouru injections could furthest strengthen ORR, improve the quality of life, reduce nausea and vomiting, and reduce the incidence of leukopenia (III-IV). Conclusions: Kanglaite injection, Astragalus polysaccharides injection, Yadanziyouru injection were superior to other CHIs in clinical efficacy and safety for GC. The conclusions now need to be confirmed by large sample size direct head-to-head studies.

• Journal of The Korean Society of Agricultural Engineers
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• v.58 no.1
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• pp.81-90
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• 2016

The Agricultural Systems Application Platform (ASAP) provides bottom-up modelling and simulation environment for agricultural engineer. The purpose of this study is to expand usability of the ASAP to the second order partial differential equations: elliptic equations, parabolic equations, and hyperbolic equations. The ASAP is a general-purpose simulation tool which express natural phenomenon with capsulized independent components to simplify implementation and maintenance. To use the ASAP in continuous problems, it is necessary to solve partial differential equations. This study shows usage of the ASAP in elliptic problem, parabolic problem, and hyperbolic problem, and solves of static heat problem, heat transfer problem, and wave problem as examples. The example problems are solved with the ASAP and Finite Difference method (FDM) for verification. The ASAP shows identical results to FDM. These applications are useful to simulate the engineering problem including equilibrium, diffusion and wave problem.

• Journal of Microbiology and Biotechnology
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• v.19 no.9
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• pp.1070-1076
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• 2009

Telomerase reverse transcriptase (TERT), which prolongs the replicative life span of cells, is highly upregulated in 85-90% of human cancers, whereas most normal somatic tissues in humans express limited levels of the telomerase activity. Therefore, TERT has been a potential target for anticancer therapy. Recently, we described a new approach to human cancer gene therapy, which is based on the group I intron of Tetrahymena thermophila. This ribozyme can specifically mediate RNA replacement of human TERT (hTERT) transcript with a new transcript harboring anticancer activity through a trans-splicing reaction, resulting in selective regression of hTERT-positive cancer cells. However, to validate the therapeutic potential of the ribozyme in animal models, ribozymes targeting inherent transcripts of the animal should be developed. In this study, we developed a Tetrahymena-based trans-splicing ribozyme that can specifically target and replace the mouse TERT (mTERT) RNA. This ribozyme can trigger transgene activity not only also in mTERT-expressing cells but hTERT-positive cancer cells. Importantly, the ribozyme could selectively induce activity of the suicide gene, a herpes simplex virus thymidine kinase gene, in cancer cells expressing the TERT RNA and thereby specifically hamper the survival of these cells when treated with ganciclovir. The mTERT-targeting ribozyme will be useful for evaluation of the RNA replacement approach as a cancer gene therapeutic tool in the mouse model with syngeneic tumors.

• Journal of the Korean Society of Systems Engineering
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• v.7 no.2
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• pp.7-11
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• 2011

A high-speed railway system represents a typical example of large-scale multi-disciplinary system, consisting of subsystems such as rolling-stock, electrical hardware, electronics, control, information, communication, civil technology etc. The system design and acquisition data of the large-scale system must be the subject under strict configuration control and management. Systems engineering technology development project for Korea next generation High-speed Electric Multiple Unit (HEMU) system in progress is a national large system development project that is not only a large-size and complex but also multi-disciplinary in nature. Therefore, all stakeholders must understand and share the functional and performance requirements of HEMU throughout its life-cycle phases. Also in the test and evaluation phase, all systems requirements must be verified. In 2011, the prototype train manufacturing will be completed. It will do test run on the commercial line and all systems requirements are verified until 2012. For the system verification, the test and evaluation process have to be established before the test trial run. Using a systems engineering tool, the system design database(SDD) with requirements traceability and development process management in the course of the development have to be established. This paper represents the test and evaluation process development based on the SEMP(Systems Engineering Management Plan) developed in the design stage. The test and evaluation process is refined and updated in comparison to the design stage one. The test and evaluation process consists of procedure, test and evaluation method and schedule. So through this process, it is defined that each systems requirements is verified on which test and about what time.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.4 no.5
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• pp.919-930
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• 2000

This paper treats a development of visual interactive modeling(VIM) system for ship scheduling problem in integer formulation. The ship scheduling problem can be described as "A problem which assigns ships and cargos to achieve maximum revenue from transportation" in brief. Since late 1970s there has been rapid growth in development and use of VIM as MS10R technology due to the development of computer technology and now VIM has become a important discipline in MS/OR and MIS society. Visual Interactive Modeling is a process that decision maker takes part in modeling life cycle -data collection, formulation, derivation of optimal solution and representation of solution - and interacts with a modeling system to achieve a user-solution appropriate for his/her ultimate goal. This paper suggests the methodology how to collect data, build and modify model, and represent solution using computer graphics as a major driving tool and demonstrates effective performance of a prototype system.pe system.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.4
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• pp.777-785
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• 2016

IM(Instant Messenger) chatting service can carry user's various information including life style, geographical position, and psychology & crime history and thus forensic analysis on the IM service is desirable. But, forensic analysis for KakaoTalk's chatting service is not well studied yet. For this reason, we study KakaoTalk's forensic analysis focusing on chatting service. This paper first details a general method of IM forensics investigating the previous articles about IM forensics although there are not many articles. Second, we discuss methodologies for IM forensics wherein we present analysis of table structure and method for reconstruction of chatting message. These result in the basic element of forensic tools of KakaoTalk chatting message. Last, we compare artifacts of KakaoTalk with that of WhatsApp. We conclude that these applications are, at least, different in that table structures and the ways to reconstruct chatting messages are not same and therefore digital evidences or artifacts are not same and somewhat distinct.

• Korean Journal of Materials Research
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• v.16 no.9
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• pp.584-591
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• 2006

To enhance the machinability of the austenite stainless alloys, Mn and S were added to form MnS in the austenite matrix. Recently, Ca is also added to increase machinability. The alloying elements, such as C, Mn, S, Ca, and Al, are known to affect machinability, but those roles are not well understood. In this study, the ingots, controlled of alloying elements, C, Mn, S, Ca, Al, were prepared in the 304 stainless steel. The relationship between microstructure and machinability was compared to understand the role of alloying elements. It was proved that Mn and S enhanced machinability but C reduced it by analyzing cutting force on machining in the lathe. The alloying elements, Ca and Al, made a complex oxide compound of Mn-S-Ca-Al-Si-O, which results in increasing tool life. The ferrite volume fraction was changed with alloying elements and the effect of the ferrite fraction on machining was also discussed.