• 대한한의학방제학회지
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• 제20권2호
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• pp.177-186
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• 2012

In this study, we selected some herbal formulation about a series of Chijasi-tang in Dongeuibogam by using web-based open program;Prescription Lineage Graph (http://164.125.206.43/PrescriptionLineageGraph.aspx). And we compared and analyzed the changes of efficacy, major target symptoms of each herbal formulation according to compositional variation of each herbal formulation. Chijasi-tang, first appeared in Sanghanlun, consists of Capejasmine and Fermented soybean, and it is mainly used to treat insomnia due to vexation, heartburn and yellow greasy tongue fur. Capejasmine can clear away irritable feverish sensation in chest by flowing downward the heat, and Fermented soybean can disperse stagnated heat throughout the chest by expelling stagnated heat from the exterior In the case of the heat stagnation caused by relapsing of disease due to overstain, Chisijisil-tang can be used. And if symptom appear more on the upper or exterior than a case of Chisijisil-tang, Seosisi-tang could be more suitable, if half exterior and half interior, Omae-tang could be for it. In addition, if symptom caused by relapsing due to improper diet, Chisijihwang-tang could be proper formulation. In the case of the heat stagnation body inside and jaundice, if it is caused by alcohol, Chijadaehwang-tang could be used for the purpose of urgent purgation, Galchul-tang would be suitable for helping the function of the spleen and the stomach and for treatment of damp-heat of the spleen and the stomach. And if it is caused by pandemic infection, Jangdal-hwan would be good formulation for it. Samhwangseokgo-tang and Yangdokchija-tang could be appropriate formulation for the raging of noxious heat and pathogenic fire caused by febrile disease with toxic yang. Daehwangeum-ja is for severe constipation due to heat-dryness with stagnated fever, Haebaek-tang is appropriate for severe diarrhea due to heat type change of Soeum. According to the result of our investigation, although there are various target causes and symptoms of each herbal formulations, whatever pathogenetic cause is, the stagnated heat in interior side is the basis of symptoms. Therefore, the purpose of including Chijasi-tang in composition of each herbal formulation is treatment of the stagnated heat. For such reason, on the fundamental or ancillary basis of Chijasi-tang plus some herbs for each therapeutic purpose.

• Restorative Dentistry and Endodontics
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• 제25권4호
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• pp.587-598
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• 2000

Urea in the oral cavity is hydrolyzed mainly by bacterial ureases to ammonia, which in turn, raises pH of the oral environment, maintaining oral pH homeostasis, thereby inhibiting dental caries. Streptococcus salivarius has been shown to be a major contribution to oral ureolysis. Synthesis of urease by S. salivarius appears to be constitutive, but can be greatly enhanced in the acidic environment. It has been presumed that ureolytic activity of S. salivarius strains isolated from caries-active site is greater than that of strains from caries-free site. However, no in vivo study has supported the presumption. The present study was performed to observe the ureolytic activity of S. salivarius strains isolated from different environments in the same individual, finding out whether the ureolytic activity is related to dental caries. For the purpose, S. salivarius strains were isolated from caries-active site (>C2), a caries-free site of the tooth, and the dorsum of the tongue of each of 50 patients having decayed teeth. The strains isolated from the patients who harbored S. salivarius in more than two sites were selected and then their ureolytic activities were measured. In order to examine clonal diversity of the strains, their ureC genes were amplified by polymerase chain reaction (PCR) and then restricted with EcoRV, and the protein profiles of the strains were compared by SDS-PAGE. The results were as follows: 1. Of 50 patients, 13 patients harbored S. salivarius in more than two sites; a total of 61 S. salivarius strain were isolated from the patients and selected for the study. 2. Of 17 isolates from the caries-active site of 9 patients harboring S. salivarius in more than two sites including carious lesion, 10 (58.8%) showed a high ureolytic activity (> 200 ${\mu}mol/min/mg$). While, 19 out of 44 isolates (43.2%) from the caries-free site of the teeth and the dorsum of the tongues of 13 patients were the strains with a high ureolytic activity. 3. Of 9 patients harboring S. salivarius in more than two sites including caries-active site. 6 patients were found to have the strains in the caries-active site showing a lower ureolytic activity than the strains in the other sites. 4. Of 34 isolates with ureolytic activity higher than 40 ${\mu}mol/min/mg$, 32 isolates produced 0.54-Kbp PCR products regardless of the sites of bacterial collection. In contrast, of 27 isolates with ureolytic activity lower than 40${\mu}mol/min/mg$, 26 isolates yielded 1.3-Kbp PCR products or none regardless of the sites. 5. Different clonal types of S. salivarius with relatively higher and lower ureolytic activities were found in the same individuals and even in the same sites. 6. None of strains showing different ureolytic activity appeared to be the same clonal type. The overall results suggest that ureolytic activity of the isolates does not appear to be related to differences of the environments but related to their own genetic traits.

• 한국지역지리학회지
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• 제2권2호
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• pp.173-182
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• 1996

본 연구는 경상남도 밀양군에 위치하는 천황산 talus에 대한 수 차례의 현지조사를 통하여 그것의 지형적 특성과 성인을 분석하여 보았으며 주된 결과는 다음과 같다. 첫째, 연구지역의 talus는 한반도에서 흔히 볼 수 있는 talus와는 상이한 지형적 경관을 보여준다. 둘째, 암설의 입경과 talus의 규모 그리고 사면경사는 비교적 큰 편에 해당된다. 셋째, talus 형성의 전제 조건인 금애면은 완전히 평행후퇴하여 지금은 소멸되었다. 넷째, 연구지역의 talus는 지난 빙기의 주빙하적 기후환경하에서 생성된 각력의 암설들이 rock fall 상태로 금애면 아래에 집적되어 형성되었다. 다섯째, 급애면의 완전소멸로 현재는 더 이상 암설의 추가공급이 이루어지지 않고 있을 뿐만 아니라 구성암설의 이동성도 인정되지 않아 지형발달단계상 화석지형화 단계로 파악된다. 결국 이러한 지형적 경관의 특이성은 본 지형의 형성프로세서와 지형적 발달단계를 설명하는데 중요하며, talus의 유형 분류에 큰 도움을 줄 수 있다.

• 치위생과학회지
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• 제8권4호
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• pp.387-393
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• 2008

본 연구는 대구지역 일부 주민 332명을 대상으로 구취측정 및 구취실태를 조사한 결과 다음과 같은 결과를 얻었다. 1. 연구 대상자는 전체 332명 중 남자가 44.6%, 여자가 55.4%였다. 연령분포는 39세 이하가 32.5%로 가장 많았고 결혼 상태는 기혼이 82.2%였다. 직업은 무직이 28.6%로 가장 많았고 사무직이 15.7%, 전문직이 15.1%였다. 구강보건행태는 잇솔질 방법은 위아래로 닦는 사람이 46.4%로 가장 많았고 1일 잇솔질 횟수는 36.4%가 2회로 가장 많았고 55.6%가 혓솔질을 하고 있었다. 2. 구취측정시 마지막 식사시기는 1-2시간 전이 26.8%로 가장 많았고 현재 느끼는 구취인에서 63.3%가 '약간 난다'라고 하였다. 아침 식사 후가 구취가 가장 심하게 난다라고 26.3%가 응답하였고 냄새(구취)에 대한 인지는 '구린 냄새가 난다'라고 응답한 사람이 33.1%로 가장 많았다. 구취로 인해서 치과진료경험이 있는 사람이 11.4%였으며 구취치료에 대한 요구도가 63.9%였다. 3. 대상자의 구취농도는 100 ppb~149 ppb가 156명이며 평균 122.76 ppb였으며, 150 ppb이상은 54명이며 평균 195.26 ppb였으며 대상자의 63.3%가 구취관리 및 치료가 필요한 것으로 나타났다. 연령이 증가 할수록 구취농도가 높게 나타났으며(p < 0.05) 현재 느끼는 구취인지 정도가 높을수록 실제 구취농도가 높았고(p < 0.001). 구취로 인한 치과진료경험이 있는 사람이 구취농도가 높았다(p < 0.01). 본 결과를 바탕으로 대상자의 구취에 대한 지식 및 관리법의 미숙한 점과 구취에 대한 인지능력이 정확하지 않은 것을 고려해 볼 때 구취에 관한 홍보를 확대할 수 있는 기초자료수집과 계획 및 치과진료기관의 구취관리 프로그램의 활성화가 필요할 것으로 사료된다.

• 비교문화연구
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• 제53권
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• pp.1-24
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• 2018

본 논고는 근대한국 문학의 전위인 이상(李箱)의 시작품에 구사되는 프랑스어와 탈 지방성에 대한 연구이다. 이상의 시편들 속에 쓰인 기호와 외래어는 한글로는 표현이 어려운 물리학, 건축학, 수학, 기하학, 이국의 문명과 같은 초감각적인 이미지들을 그려내고, 의미생성과 확장을 불러오는 파생의 시어로 작용한다. 이상의 시작품에서 프랑스어는 알파벳 철자와 한글식의 표기로 나누어지고, 문장들은 고딕 적이며, 병렬적인 이미지를 보여준다. 프랑스어 단어들은 "${\Box}$, ${\triangle}$, ${\nabla}$" 등의 기호들과 조화를 이루어 상형적인 이미지로 기술된다. 문법의 규범을 이탈한 문장들은 해체와 재조합을 불러오고, 이때 프랑스어는 한글을 대체하고, 모국어가 갖는 한계를 초극하여 이국의 과학문명과 사상, 예술을 차용하는 포스트모던의 시어로 활용된다. 나아가 "ESQUISSE" 등의 프랑스어는 시인 자신의 열등의식을 초월하고, 자유와 상상력, 현대의 예술정신을 구현하기 위한 전위적인 시어로써, "향토"(鄕土)의 조선 문단에 세계의 신경향을 이식하여 성숙시켜 놓은 탈 지방의 시어로 나타난다.

• 대한정형외과학회지
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• 제54권5호
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• pp.463-468
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• 2019

선천성 무통증과 무한증(congenital insensitivity to pain with anhidrosis, CIPA)은 감각신경계와 자율신경계가 이환되는 질환으로 상염색체 열성으로 유전되는 드문 질환이다. 우리 환자는 방치된 원위 대퇴골 골절로 내원한 5세 여아로 추시 도중 시행한 방사선 사진에서 과도한 가골과 가관절 소견을 보였으며, 손가락의 절단, 반복적인 불명열의 과거력을 갖고 있었다. 근전도/신경전도 검사에서는 이상 소견이 관찰되지 않았고, 정량적 발한 축삭 반사검사에서는 한선의 분비 기능이 거의 없는 소견을 보여 이를 바탕으로 CIPA로 진단하였다. 매우 드문 질환이고 감각자율신경계 질환이기 때문에 정형외과 의사가 CIPA 환자를 만날 확률은 매우 낮지만 본 증례의 경우처럼 정형외과 의사가 CIPA를 처음으로 진단하는 의사가 될 수도 있으므로 그 가능성을 염두에 두어야 하겠다.

• 대한중풍순환신경학회지
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• 제11권1호
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• pp.26-35
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• 2010

Objective : The aim of this study was to examine the characteristics of the acute stroke patient who take Gwakhyangjeonggisan, and provide the basis of Gwakhyangjeonggisan prescription Method : We studied hospitalized patients within 4 weeks after their ictus who were admitted at Kyunghee University Oriental Medical Center, Kyunghee University East-West Neo Medical Center, Kyungwon University Oriental Medical Center, Semyung University Oriental Medical Center from February 2010 to July 2010 We compared the general characteristics of acute stroke patient according to herb medicine Result : The patient who take Gwakhyangjeonggisan show significant difference for sex, family history of Stroke, Face color, Tongue color, Pulse condition, HDL Cholesterol, Fastfood eating, Waist circumference. Conclusion : The above result show that Gwakhyangjeonggisan can be prescribed to stroke patient whose complaining gastrointestinal symptoms, & Oriental Medical Diagnosis is Cold & Deficiency type. Further studies will be needed to better understand the difference between Gwakhyangjeonggisan group and Other herb medicine among acute stroke patients.

• 말소리와 음성과학
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• 제16권2호
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• pp.37-47
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• 2024

본 연구는 대중가요 관련학과에서 보컬을 전공하고 있거나 입시를 준비하는 전공하는 남성 27명을 대상으로 자신의 성종과 음역을 제대로 파악하고 있는지를 살펴보기 위해 주관적으로 평가한 성종과 음향학적으로 평가한 성종 간에 차이가 있는지를 비교하였고, 성종 간 기본주파수(fundamental frequqency, F0)와 평균발화기본주파수 간의 차이도 비교하였다. 또한, 이들이 모음에 따라 고음역에서 산출할 수 있는 정도가 다를 수 있으므로 극모음인 /a/, /i/, /u/ 모음 간 음역의 차이와 성종별로 구분하여 모음 간 음역의 차이가 있는지를 살펴보았으며, 모음별로 성종 간에 음역의 차이가 있는지도 비교하였다. 연구 결과, 대중가요 보컬을 전공하거나 입시를 준비하는 남성의 절반 이상이 본인의 성종을 정확하게 파악하지 못하고 있으며, 모음 간에 최대기본주파수와 주파수범위는 통계적으로 유의한 차이를 보여 모음의 종류에 따라 산출할 수 있는 음역의 차이가 있음을 알 수 있었다. 특히 모음 /a/>/u/>/i/ 순으로 음역이 감소하였다. 이는 모음 /a/가 다른 모음에 비해 고음역에서 조음하기에 용이하지만, 모음 /u/와 /i/는 고모음으로 혀의 위치가 상승함으로써 구강 면적이 좁아지고 후두의 상승이 동반되기 때문에 음역이 감소하고 고음에서 발성하기에 어려움이 초래된다는 것을 알 수 있다.

• 대한한방내과학회지
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• 제29권4호
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• pp.970-978
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• 2008

Objectives : This study aimed to clarify the relationship between the Oriental medical diagnosis and arteriosclerosis by measuring carotid-ankle vascular index(CAVI) in acute cerebral infarction patients. Method : One hundred thirty-one subjects were recruited from the patients admitted to the Internal Medical Department at Kyunghee University Oriental Medical Center from April 2007 to August 2008. We sorted cerebral infarction patients and assessed one hundred fourteen patients' CAVI data. We diagnosed dampness-phlegm by Oriental medical diagnosis and evaluated stroke type by single or multiple infarctions. then, we analyzed their characteristics with type of stroke, risk factor, lifestyle, metabolic syndrome and dampness-phlegm diagnosis. Result : 1. On the demographic variables of the patients, age, hypertension, hyperlipidemia, multiple infarction group and metabolic syndrome and dampness-phlegm group were significantly higher in the high CAVI score group than in the control. 2. According to the significant difference in the dampness-phlegm group, we analyzed dampness-phlegm related index for pattern identifications by CAVI score. As a result, dark circles, insomnia, headache, white coating tongue. slippery pulse, and rough pulse were significantly higher in the high CAVI score group then in the control. 3. In multivariate analysis, age, hypertension, multiple infarction and dampness-phlegm groups showed a close relationship with the high CAVI score group. Conclusions : According to the analysis, significance between dampness-phlegm diagnosed patients group and high CAVI score were clarified. Moreover, multiple location infarctions also have a relationship with high CAVI score in cerebral infarction patients. These results can be utilized in the future as a basis material.

• 한국치위생학회지
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• 제8권4호
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• pp.115-125
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• 2008

The purpose of this study was to examine the relationship between the Dentocult SM and LB scores of students and their DMF rate. The subjects in this study were 134 special school students in south Gyeong-sang province. After they were tested to find out their, they received tooth brushing education and preventive treatment. The test, education and treatment were all conducted from March 17 to April 9, 2008. Their oral state was checked and recorded by using a mirror and explorer, and then the data on oral state were analyzed to their DMFT, DT, FT and MT rates. All the collected data were analyzed with SPSS 15.0 for Windows program, and independent-samples t-test, one-way ANOVA and crosstabs analysis were implemented to see what differences their disability type, gender, Dentocult-SM scores and Dentocult-LB scores made. The findings of the study were as follows: 1. As for connections between disability type and DMFT rate, the students with mental retardation were similar to the other students in that regard. The mentally retarded students had higher DT and FT rates than the other students, and the MT rate of the latter was higher than that of the former. 2. Concerning the relationship of gender to DMFT and DT rates, the girls had larger DMFT and DT rates than the boys, and the FT and MT rates of the boys were higher than those of the girls. 3. As to links between Dentocult SM scores on the tongue and DMFT, the students whose bacteria was mildly activated had the highest DMFT rate, and the students who had a severely activated bacteria had the highest DT and FT rates. Those who had a moderately activated bacteria had the highest MT rate. 4.Regarding the connection of Dentocult SM scores on maxillyright molar to DMFT and DT rates, the students whose bacteria was severely activated had the highest DMFT and DT rates. Those who had no activated bacteria had the largest FT rate, and the students who had a mildly activated bacteria had the highest MT rate. 5.Regarding the connection of Dentocult SM scores on maxillyleft molar to DMFT and DT rates, the students whose bacteria was severely activated had the highest DMFT and DT rates. Those who had no activated bacteria had the largest FT rate, and the students who had a mildly activated bacteria had the largest MT rate. 6. Regarding the connection of Dentocult SM scores on mandibularright molar to DMFT and DT, FT rates, the students whose bacteria was severely activated had the highest DMFT and DT, FT rates. Those who had a moderately activated bacteria had the highest MT rate. 7. Regarding the connection of Dentocult SM scores on mandibularleft molar to DMFT and DT rates, the students whose bacteria was mildly activated had the highest DMFT and DT rates. Those who had no activated bacteria had the largest FT rate, and the students who had a moderately activated bacteria had the highest MT rate. 8. Regarding the connection of Dentocult LB scores to DMFT and DT rates, the students whose bacteria was severely activated had the highest DMFT and DT rates. Those who had no activated bacteria had a moderately FT rate, the students who had a mildly activated bacteria had a mildly MT rate.