• 대한예방한의학회지
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• 제22권1호
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• pp.15-28
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• 2018

Objectives : The purpose of this study was to analyze the trend of clinical research on quantitative indicators of Mibyeong in traditional chinese medicine(TCM). Method : The journal search was performed using china national knowledge infrastructure(CNKI) database. Our inclusion criteria were as following: TCM clinical researches for quantitative indicators of Mibyeong. Exclusion criteria were as following: non-TCM clinical researches, used intervention methods. Results : Eleven clinical researches were analyzed in this study. Four of these researches classify the Mibyeong as a type of pattern identification(PI) and studied the characteristics of the PI quantitative indicators. Mibyeong diagnosis was done through guidelines and questionnaires, each was used at a similar rate. Quantitative indicators mentioned in the selected researches were blood indices, nailfold capillary, complexion, color of tongue substance and coating, pulse wave diagrams and heart rate variability. Among them, seven researches related to blood indices were the most. Blood indicators include whole-blood viscosity, plasma viscosity, fibrinogen, packed cell volume(Hct), triglycerides, total cholesterol, HDL-C, LDL-C, glucose, BUN/CREA, luteinzing hormone, estradiol, follicle stimulating hormone, IgA, IgG, etc. Conclusions : Based on this results, in combination with western medicine, it seems necessary to try to interpret the Mibyeong in more various ways. Even if the same Mibyeong, it is necessary to identify the index which changes according to the PI or chief complaint, and to set the Mibyeong standard corresponding thereto.

• 한국치위생학회지
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• 제11권1호
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• pp.81-94
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• 2011

Objectives : This study conducted to investigate oral care abilities in diabetic patients to find a good dental method which may efficiently control diabetes. Methods : The diabetic group consisted of 40 patients with type 2 diabetics, while the non-diabetes were 34 persons with no signs of diabetics, who had visited a Public Health Center and dental clinic of a general hospital in Gwangju city from Dec. 2008 to Sep. 2009. Periodontal disease, gingivitis, dental caries, tongue plaque and halitosis between diabetic group and non-diabetic group were examined and at the same time a questionnaire survey was conducted. The data were analyzed with chi-square, t-test, pearson correlation coefficients using the SPSS WIN 15.0 program. Results : The mean values of both the community periodontal index and the gingival index of diabetic group were 2.18 and 1.75, respectively, and those were higher than those (1.79 and 1.50) of non-diabetic group with no statistical significance. The mean saliva secretion of non-diabetics was 16.74 mL, which was higher than 13.90 mL of diabetic patients(p<0.05). The oral care ability(mean 3.10) acquired from plague index in diabetic group was worse than in non-diabetic(mean 2.33). Conclusions : The high blood sugar concentration in diabetic patients causes low saliva secretion and high saliva viscosity, with the results halitosis and periodontal disease take place. This study suggested that good oral care ability of diabetic patients was very helpful to prevent periodontal disease and halitosis. In addition to this, it may reduce complications of diabetic patients.

• 디지털융복합연구
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• 제15권10호
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• pp.307-314
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• 2017

본 연구에서는 하악전방이동 코골이 장치의 종류에 따라 최소한의 수직 교합량을 각각 다르게 확보하여 1급 교합을 가진 대상이 각 장치를 착용한 뒤, 수직 교합량이 하악의 위치, 근육의 변화, 혀의 위치등을 부가적으로 변화시켜 상기도의 면적에 영향을 주는 지 알아보고자 하였다. 수직량이 높을수록 상기도의 면적은 감소했으며, 혀의 위치를 후방으로 처지지 않게 할수록 상기도의 면적이 증가함을 알 수 있다. 코골이 감소를 위해 의사들은 환자들의 교합관계를 정확하게 진단하여 그 교합에 맞는 하악전방이동 코골이 장치를 선택해야 하고, 선택된 장치를 제작하는 치과 기공사 또한 장치의 효과를 높이기 위해 수직 교합량, 후방연 설정과 장치의 두께 등 디자인 설정을 고려해야 한다.

• 대한음성학회:학술대회논문집
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• 대한음성학회 2007년도 한국음성과학회 공동학술대회 발표논문집
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• pp.71-73
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• 2007

The Purpose of the study is to give Korean-English leaners better knowledge on vowel sounds in their learning English. The traditional description of the cardinal vowel system developed by Daniel Johns in 1917 is not enough to provide English learners with clear ideas in producing native like vowel sounds. For the reason, three Korean-native subjects, one male, one female and one child are chosen to produce 7 cardinal vowels and compare them with native English and American speaker's vowel sounds. The difference of produced vowels sounds is quantified and visualized by employing Sona-match program. The results have been fairly remarkable. Firstly, Korean-English learner's vowel sounds are articulated differently from their intention of vowel production. Secondly, the tongue positions of Koreans are placed slightly more down and forward to the lips than those of English and Americans. However, the front vowel /i/ sound is quite close to English and Americans. Lastly the mid-vowel /${\partial}$/ sound is not produced in any articulations of Korean-native speakers. It is thought that the mid vowel, /${\partial}$/ is a type of a weak sound regarded as 'schwa' which needs a great deal of exposure to the language to acquire a physical skill of articulation.

• 대한두경부종양학회지
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• 제12권2호
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• pp.147-152
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• 1996

For advanced head and neck cancers that originate in midline structures, bilateral neck dissection should be considered even if the lymph nodes were negative clinically. But, many complications and mortalities may occur in synchronous bilateral neck dissection at sacrifing of both internal jugular vein. Therefore several types of bilateral neck dissection have been proposed, but the effective and safe methods were not determined yet. So, we have prefered the method of synchronous bilateral neck dissection with preserving one internal jugular vein at least. We operated 21 patients who might be expected high incidences of bilateral neck metastases with above type of neck dissection. We analyzed the data of 21 cases(42 sides) retrospectively. The results were as follows: 1) The primary sites were transglottic(33%), supraglottic(29%), hypopharynx(29%) and tongue base(9%). 2) Types of neck dissection were RND(4 sides), MND(7 sides), FND(16 sides), and SND (15 sides). 3) Postoperative complications were minimal and did not influenced morbidity. 4) Mean interval time of neck recurrence was 21 months. Overall neck recurrent rate after bilateral neck dissecton was 19%. In 19%, neck recurrence from positive lymph nodes was 63% and from negative lymph nodes was 37%. As a results, synchronous bilateral neck dissection with preservation of one internal jugular vein minimally should be done in cases which were suspected high incidence of bilateral lymph node metastases for cure and prevention of neck recurrence.

• Asian Pacific Journal of Cancer Prevention
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• 제16권12호
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• pp.5107-5110
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• 2015

The State of Punjab has been in focus because of aperceived increasing rate of cancer. Both print and electronic media have created an impression that Punjab, especially the cotton belt of Malwa Region, has become a high incidence cancer region. Actually the increased number of cancer patients might be at least partly because of increasing population and heightened health awareness and reporting. The purpose of this study is to find out the pattern of cancer amongst patients registered in Mukh Mantri Punjab Cancer Rahat Kosh Scheme (MMPCRKS), under cancer registry at Rajindra Hospital Patiala from the various districts of Punjab. The study covers 500 cancer patients registered under MMPCRKS at Rajindra Hospital Patiala, for free cancer treatment. Information regarding age, gender, religion, method of diagnosis and affected sites was obtained. Results were analyzed statistically. Of the 500 patients, 65% were females and 35% were males. The most affected female age groups were 50-54 and 60-64; while males in the age groups of 65-69 and 60-64 had the highest risk. The leading cancers in females were breast followed by cervix and ovary where as in males they were were colon followed by esophagus and tongue. The commonest histological type was adenocarcinoma followed by squamous cell carcinoma. The increasing trend of cancer in Punjab is alarming. Since this study is a preliminary investigation, it could provide a leading role in prevention, treatment and future planning regarding cancer in Punjab.

• Parasites, Hosts and Diseases
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• 제48권3호
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• pp.213-217
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• 2010

Sarcocystis sp. infection was investigated in 20 necropsied captive wild mammals and 20 birds in 2 petting zoos in Malaysia. The gross post-mortem lesions in mammals showed marbling of the liver with uniform congestion of the intestine, and for birds, there was atrophy of the sternal muscles with hemorrhage and edema of the lungs in 2 birds. Naked eye examination was used for detection of macroscopic sarcocysts, and muscle squash for microscopic type. Only microscopically visible cysts were detected in 8 animals and species identification was not possible. Histological examination of the sections of infected skeletal muscles showed more than 5 sarcocysts in each specimen. No leukocytic infiltration was seen in affected organs. The shape of the cysts was elongated or Circular, and the mean size reached $254{\times}24.5{\mu}m$ and the thickness of the wall up to $2.5{\mu}m$. Two stages were recognized in the cysts, the peripheral metrocytes and large numbers of crescent shaped merozoites. Out of 40 animals examined, 3 mammals and 5 birds were positive (20%). The infection rate was 15% and 25% in mammals and birds, respectively. Regarding the organs, the infection rate was 50% in the skeletal muscles followed by tongue and heart (37.5%), diaphragm (25%), and esophagus (12.5%). Further ultrastructural studies are required to identify the species of Sarcocystis that infect captive wild animals and their possible role in zoonosis.

• The Korean Journal of Pain
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• 제2권1호
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• pp.57-60
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• 1989

The Melkersson-Rosenthal (M-R) syndrome consists of a triad of (1) recurrent peripheral facial nerve paralysis which develops alternately on both sides of face, (2) non-inflammatory facial edema, and (3) fissuring of tongue. A 59 years old female patient developed the left facial palsy on September, 1988. Right facial palsy developed continuously 2 months later after the spontaneous remission of left facial palsy. On February, 1989, we have found out M-R syndrome which accompanied with migraine type of intermittent headache, and hypertension in one attack of cerebral stroke several years ago, there were no diabetes mellitus, pulmonary tuberculosis and brain tumor in clinical studies. Although the causes of this syndrome were not noted, we performed the stellate ganglion block and transcutaneous electrical nerve stimulation for treatment of the palsy, but the clinical effectiveness of these were not satisfactory.

• International Journal of Oral Biology
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• 제45권1호
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• pp.1-7
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• 2020

Oral lichen planus (OLP) is a chronic inflammatory disease observed in approximately 0.5-2.2% of the population, and it is recognized as a premalignant lesion that can progress into oral squamous cell carcinoma (OSCC). The rate of malignant transformation is approximately 1.09-2.3%, and the risk factors for malignant transformation are age, female, erosive type, and tongue site location. Malignant transformation of OLP is likely related to the low frequency of apoptotic phenomena. Therefore, apoptosis-related genetic factors, like p53, BCL-2, and BAX are reviewed. Increased p53 expression and altered expression of BCL-2 and BAX were observed in OLP patients, and the malignant transformation rate in these patients was relatively higher. The involvement of microRNA (miRNA) in the malignant transformation of OLP is also reviewed. Because autophagy is involved in cell survival and death through the regulation of various cellular processes, autophagy-related genetic factors may function as factors for malignant transformation. In OLP, decreased levels of ATG9B mRNA and a higher expression of IGF1 were observed, suggesting a reduction in cell death and autophagic response. Activated IGF1-PI3K/AKT/mTor cascade may play an important role in a signaling pathway related to the malignant transformation of OLP to OSCC. Recent research has shown that miRNAs, such as miR-199 and miR-122, activate the cascade, increasing the prosurvival and proproliferative signals.

• 대한음성학회지:말소리
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• 제4호
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• pp.20-30
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• 1982

The aim of this paper is to analyse difficulties of the pronunciation in swedish vowels encountered by Koreans learners and to seek solutions in order to correct the possible errors. In the course of the analysis the swedish and Korean vowels in question are compared with the purpose of describing differences aha similarities between these two systems. This contrastive description is largely based on the students' articulatory speech level ana the writer's auditory , judgement . The following points are discussed : 1 ) Vowel length as a distinctive feature in Swedish compared with that of Korean. 2) A special attention is paid on the Swedish vowel [w:] that is characterized by its peculiar type of lip rounding. 3) The six pairs of Swedish vowels that are phonologically contrastive but difficult for Koreans to distinguish one from the other: [y:] ~ [w:], [i:] ~ [y:], [e:] ~ [${\phi}$:], [w;] ~ [u:] [w:] ~ [$\theta$], [$\theta$] ~ [u] 4) The r-colored vowel in the case of the postvocalic /r/ that is very common in American English is not allowed in English sound sequences. The r-colored vowel in the American English pattern has to be broken up and replaced hi-segmental vowel-consonant sequences . Korean accustomed to the American pronunciation are warned in this respect. For a more distinct articulation of the postvocalic /r/ trill [r] is preferred to fricative [z]. 5) The front vowels [e, $\varepsilon, {\;}{\phi}$) become opener variants (${\ae}, {\;}:{\ae}$] before / r / or supradentals. The results of the analysis show that difficulties of the pronunciation of the target language (Swedish) are mostly due to the interference from the Learner's source language (Korean). However, the Learner sometimes tends to get interference also from the other foreign language with which he or she is already familiar when he or she finds in that language more similarity to the target language than in his or her own mother tongue. Hence this foreign language (American English) in this case functions as a second language for Koreans in Learning Swedish.