• 대한핵의학회지
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• 제27권2호
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• pp.183-190
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• 1993

저자들은 이소갑상선이 의심되어 갑상선신티그라피로 확진된 19명의 환자를 대상으로 갑상선 스캔과 갑상선 기능검사의 결과 및 임상증상등을 조사하여 다음과 같은 결과를 얻었다. 1) 이소갑상선의 성별분포는 여자 16명, 남자3명으로 여자가 남자의 5.3배였고, 30세 이전인 경우가 97%였다. 2) 이소갑상선이 발견된 위치는 설근부 10예, 설하부1예, 전 후두부 5예 그리고 Combined form이 3예였다. 3) 갑상선기능검사를 시행한 16예에서 갑상선기능저하증이 7예, 준임상적 갑상선기능저하증이 4예 그리고 갑상선기능 정상이 5예였다. 4) 설갑상선의 경우는 갑상선기능저하증이 90%에서 나타났으나, 이보다 아래로 내려온 경우에는 33%로 갑상선 기능이상은 이소갑상선의 위치에 따라 유의한 차이가 있었다(p<0.05). 5) 갑상선의 주된 임상증상은 설근부의 인후이물감, 연하곤란이었고, 이보다 아래에 위치한 경우는 전경부의 종괴가 주된 임상증상이었다. 6) 갑상선기능저하증으로 진단된 7예와 준임상적 갑상선 기능저하증 4예중 3예에서는 갑상선호르몬을 투여하였고 갑상선 기능이 정상인 2예에서 이소갑상선 제거술이 시행되었으며 그 나머지는 추적관찰하였다. 7) 설근부나 전경부에 종괴가 있을 경우에는 반드시 갑상선스캔을 시행하여 이소갑상선의 가능성을 배제하여야 한다. 또한 이소갑상선의 기능이 정상인 환자에서도 갑상선기능저하증으로 진행될 수 있으므로 추적관찰이 필요하다.

• 대한치과교정학회지
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• 제20권1호
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• pp.197-207
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• 1990

This comparative study was undertaken to investigate the position of the hyoid bone in unilateral cleft lip and palate individuals. The materials for this study consisted of 35 subjects with surgically repaired unilateral cleft lip and palate (25 males, 10 females) and 40 subjects with normal facial morphology (20 males, 20 females). Cephalometric measurements of unilateral cleft and palate individuals were compared with those of non-cleft individuals. The conclusions of this study were obtained as follows: 1. To the anterior cranial base, the hyoid bone in unilateral cleft lip and palate individuals was located downward as compared with non-cleft individuals. 2. To the mandible, the hyoid bone in unilateral cleft lip and palate individuals was located backward as compared with non-cleft individuals. 3. The distance between the dorsum of the tongue and the inferior border of the hard palate in unilateral cleft lip and palate individuals was longer than that in non-cleft individuals. 4. Unilateral cleft lip and palate individuals showed no significant difference in the distance between the hyoid bone and the dorum of the tongue as compared with non-cleft individuals.

• 생물정신의학
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• 제5권1호
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• pp.129-133
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• 1998

Objective : Base on clinical practice, the authors report a case of tardive dyskinesia arising during the course of treatment with resperidal. Methods : This article was review and analysis of a case on risperidone-induced tardive dyskinea. Results : Mrs K, a 51-year-old woman with a 1-year history of schizophrenic disorder, gradually developed tardive dyskinetic movement of the mouth, lip, and tongue over a 4 month period(From July, 1996 to June, 1997) while taking risperidone. Initially she was treated with haloperidol and alprazolam. However, the haloperidol was subsequently discontinued because of EPS developed. From 11th March, 1997, she was observed to have a severe form of tardive dyskinesia involving her tongue, lip, and mouth. After risperidone was withdrawn at 9th May 1997, her tardive dyskinetic movement was disappeared. Conclusions : This is, to our knowledge, the first report of the onset of tardive dyskinesia in a patient taking risperidone. However, additional controlled studies of specific questions are needed ; e.g., the dose-response curves for produce tardive dyskinesia and the mechanism of producing risperidone-induced tardive dyskinea and so on.

• 대한치과교정학회지
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• 제37권3호
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• pp.192-203
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• 2007

본 연구는 비폐쇄를 보이는 III급 부정교합아동에서, 기도 공간의 형태와 안모 골격 형태 사이의 상관관계를 평가하였다. III급 부정교합을 보이며, 비폐쇄 소견을 보여 이비인후과로 의뢰된 환아 100명의 초진 측모 두부 규격 방사선 사진에서 상 인두기도 공간(upper PAS), 하 인두기도 공간(lower PAS), 편도의 크기, 구개-혀 공간을 측정하여 기도 공간 형태를 분석하였으며, 통상적인 계측점을 사용하여 안면 골격 분석을 시행하여 기도 공간 형태 계측항목과 안면 골격분성 항목간의 상관관계를 연구하여 다음과 같은 결과를 얻었다. Upper PAS는 ramal height, SNA, SNB, PFH, FHR, facial plane angle 항목과 양의 상관관계를 보였으며, saddle angle, articular angle, gonial angle의 sum, SN-GoGn, Y-axis to SN, FMA 항목과 음의 상관관계를 보였다. Lower PAS는 genial angle, FMA와 양의 상관관계를 보였으며, articular angle, facial depth, PFH, FHR와 음의 상관관계를 보였다. 편도의 크기는 PCBL, ramal height, Mn. body length, Mn. body length to ACBL, facial depth, facial length, PFH, AFH와 양의 상관관계를 보였다. 구개-혀 공간은 saddle angle, articular angle, genial angle의 합, facial length, AFH, FMA, LFH와 양의 상관관계를 보였으며, IMPA, overbite와 음의 상관관계를 보였다.

• 대한수의학회지
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• 제30권4호
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• pp.395-400
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• 1990

A female Korean native calf with diprosopus was examined macroscopically and radiographically. Anterior head duplication (diprosopus) was observed and all structures caudal to it were normal. She had two complete mouths, four eyes and three ears. Single tongue was present in each oral cavity. The two tongues were joined at their base just posterior to the single epiglottis. Both oral cavities led jointly into a common pharynx and one esophagus. One laryngeal cavity communicated with one common trachea. The lower jaws were immobile because of overlapping mandibular rami. The atlas was complete, and two anterior articular cavities articulated with the lateral condyles of the occipital bones of each skull. The cerebrums were fused each other at their caudal portion, and the giri and sulci were underdeveloped. The cerebellums were also completely fused, and they had not characteristic appearance of the vermis. The spinal cord showed normal appearance.

• 대한음성언어의학회:학술대회논문집
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• 대한음성언어의학회 2003년도 제19회 학술대회
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• pp.147-147
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• 2003

Recent aerodynamic and acoustic studies of VPI(velopharyngeal insufficiency) are non-invasive and safety, therefore, many researchers have used it to diagnose the hyper/hyponasality and articulation disorders of cleft palate patients. The purpose of this study was to estimate mainly the oropharyngeal air pressure and over all air flow in cleft lip and palate patients. The pressure-collecting catheter was positioned in the oropharyngel cavity around tongue base. Twelve adult control group and three cleft lip & palate patients were participated to this experimentation. Aerophone II was used to measure peak air flow, mean air flow, phonatory airflow, phonatory efficiency and resistance. The results were as follows: 1) Airflow of cleft lip ＆ palate patients group were higher than those of control group. Fricative sounds /s/ and /s'/ showed the statistic significance of mean airflow and volume data. 2) Intraoral air pressure of cleft lip ＆ palate patients was lower than those of control group.

• 대한수의학회지
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• 제32권4호
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• pp.635-640
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• 1992

Two cases of lingual masses were observed among 500 Fischer 344 (F344) rats which were used as control and treated animals in a 2 year carcinogenicity study in Toxicology Research Center, Korea Research Institute of Chemical Technology. The masses grossly appeared as tan, pedunculated, fungiform on the dorsal aspect of the base of the tongues. They were approximately $1.5{\times}1.2{\times}0.3cm$ in size. The microscopic features consisted of acanthosis, hyperkeratosis, papillary projection with connective tissue cores and multifocal chronic active inflammation with hair shafts. The results observed support the epigenetic mechanism of tumorigenesis which is caused by Physical stimuli of foreign bodies. Both of the masses were diagnosed as papillomas with the incidence rate of 0.4%(1/250) in each sex on the basis of the gross and microscopic features.

• 대한두경부종양학회지
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• 제30권2호
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• pp.104-108
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• 2014

주로 작은 침샘에서 발생하는 샘낭암종의 치료 방침은 수술과 수술 후 보조적 방사선치료가 주로 행해져 왔다. 그러나 설근부에 발생한 샘낭암종에 대해서는 수술적 치료가 가져오는 삶의 질의 저하가 크기 때문에 수술적 치료를 적용하기 쉽지 않다. 또한 샘낭암종의 치료에 있어서 항암제의 역할이 거의 없는 상황에서 방사선치료가 중요한 역할을 할 수 있겠다. 이에 본 저자들은 설근부에 발생한 샘낭암종 세 증례의 방사선치료 결과를 보고 하며 샘낭암종의 치료에 대해서 문헌고찰을 통해 논의하고자 한다.

• 대한기관식도과학회지
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• 제3권2호
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• pp.318-322
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• 1997

Lingual thyroid is the term applied to a mass of ectopic thyroid tissue located on the base of the tongue in the midline. It may be found anywhere between the circumvallate papillae and the epiglottis. It is believed to be caused by developmental anomalies involving the descent of the embryologic gland anlage from its position posterior to the tuberculum impar to its normal pretracheal location between week 3 and week 7 of embryologic development. Differential diagnosis of the lingual thyroid would include lingual tonsillar hypertrophy, vallecular cyst, thyroglossal duct cyst, epidermal cyst, lymphoma. Lingual thyroid is found in approximately 1 in 100,000 people, and affected individuals have no other thyroid tissue in 70% to 100% of cases. Recently, we have experienced a case of lingual thyroid with mild dysphagia in a 48-year-old male. Now we report the case with literature review.

• Journal of Species Research
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• 제13권2호
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• pp.127-130
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• 2024

The first complete mitogenome sequence of the Red-tongue Pit Viper (Gloydius ussuriensis) from Korea was characterized using next-generation sequencing. The mitogenome is a circular molecule (17,209 bp) with a typical vertebrate mitogenome arrangement, which consists of 2 ribosomal RNA genes (rRNA), 22 transfer RNA genes (tRNA), two non-coding regions (D-loop), and 13 protein-coding genes (PCGs). The base composition of the mitogenome is 32.7% of A, 27.5% of C, 13.9% of G, and 25.9% of T, with a slight AT bias(58.6%). This phylogenetic analysis infers that G. ussuriensis is in the same group as the Chinese G. ussuriensis (Accession No. KP262412) and is closely related to G. blomhoffi and other species of the genus Gloydius. In our study, the complete mitogenome sequence of Korean G. ussuriensis was characterized and we provided basic genetic information on this species.