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Scientific study for Chong-Tong(Gun) from Yochon seabed (여천 해저 인양 총통의 과학적 연구)

  • Kang, Dai-ill;Kim, Sun-Duk;Hwang, Jin-Ju;Ahn, Hee-Kyun;Lim, Sun-Ki
    • 보존과학연구
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    • s.15
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    • pp.33-51
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    • 1994
  • Scientific study for Chong-Tong was carried out firstly by ICP and C /S analysis. Hyeon-Ja-Chong-Tong is made by Ryang-Ne-Ryo_Dong and identified the oldest Chong-Tong among them same items never since excavated from in Korea. It was found that Byol-Seung-Ja-Chong-Tong includes gunpowder and by $\gamma$-Radiography and casted at the 1592 just before Hideyoshi's invasion of Korea. these Chong-Tong is fired by the fuse is the muzzl-loading.

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Clinical Character of Pediatric Head and Neck Rhabdomysarcomas: A 7-Year Retrospective Study

  • Zhang, Wei-Ling;Zhang, Yi;Huang, Dong-Sheng;Guo, Fang;Han, Tao;Hong, Liang;Hu, Hui-Min;Zhi, Tian
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.7
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    • pp.4089-4093
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    • 2013
  • Objective: The rhabdomysarcoma (RMS) is most common soft tissue carcinoma in children, mostly found in the head and neck with high degree of malignancy. The current study aimed to summarize clinical data and evaluate treatment outcome of cases in a single hospital. Methods: Forty-one (24 male, 17 female) children with newly diagnosed RMS in Beijing Tong Ren Hospital were enrolled between November, 2004 and May, 2011. The. Students' t and Chi tests were then performed on retrospectively reviewed clinical data, followed by survival analysis based on the Kaplan Meier method using SPSS 17.0 software. Results: Of all cases, 32 were treated by common chemotherapy, and 3 cases with stage III RMS received high-dose chemotherapy and auto-peripheral blood stem cell transplantation (APBSCT). Side-effects in the former were: I grade for 62.5% (20/32), II grade for 28.1% (9/32), III grade account for 9.275% (3/32). Side-effects of 3 cases with APBSCT: 2 were I grade, 1 was III grade. The median follow-up time of 41 RMS cases was 41 months. Four cases were lost to follow-up, 7 cases recurred, and 5 cases died of cerebral metastasis, witha total survival rate was 86.5% (32/37). CR rate was 67.6% (25/37), PR was 18.9% (7/37). Conclusion: Multidiscipline treatment including chemotherapy, radiotherapy, surgery and auto-PBSCT is highly recommended for pediatric patients with head and neck RMS.

Analysis of the Important Herb Medications Corresponded with Neuropsychiatry of "Bang-Yak-Hap-Pyun" (방약합편(方藥合編)에 수재된 신경정신과(神經精神科) 관련 주요 처방(處方)에 대한 연구(硏究))

  • Kim, Jee-Hoon;Koo, Byung-Soo;Kim, Geun-Woo
    • Journal of Oriental Neuropsychiatry
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    • v.20 no.1
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    • pp.89-106
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    • 2009
  • Objectives : The purpose of this study is to analysis of the herb medications corresponded with neuropsychiatry of "Bang-Yak-Hap-Pyun". Methods : The herb medications of "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong(上.中.下統) and "Enlargement side prescriptions" (增補方) are selected by comment on the chief virtue including reference word of corresponded with neuropsychiatry. Results and Conclusion : "Bang-Yak-Hap-Pyun" is a book most people who have a background or career in Han Medicine(韓醫學) would pore over. They corresponded with neuropsychiatry among the herb medications of "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong(上.中.下統) are 55 prescriptions that Sang-Tong(上統) is 8 prescriptions, Jung-Tong(中.統) is 23 prescriptions and Ha-Tong(下統) is 24 prescriptions. And the herb medications corresponded with neuropsychiatry of "Enlargement side prescriptions" (增補方) are 40 prescriptions. And then the herb medications corresponded with neuropsychiatry of "Bang-Yak-Hap-Pyun" received much influence from "Dong-Eui-Bo-Gam". Incidentally the herb medications corresponded with neuropsychiatry of "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong showed the high percentage in Neurosis. And the herb medications corresponded with neuropsychiatry of "Enlargement side prescriptions" showed the high percentage in Psychosis. Besides not only put "Enlargement side prescriptions a premium on "Dong-Eui-Bo-Gam", but also made it the herb medications which were recorded on books flowed after "Dong-Eui-Bo-Gam" known. It was entered up books quoted from "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong but the herb medications were that were not succeeded from "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong. Therefore "Enlargement side prescriptions" shows the efforts for supplement of "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong.

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Home Automation System using WirelessUSB based on PSoC (PSoC 기반의 WirelessUSB를 이용한 홈오토메이션 시스템 구현)

  • Lee, Sang-Hee;Kim, Ha-Na;Jung, Chan-Ho;Lee, Jun-Hee;Shin, Dong-Suk;Kang, Sung-In;Kim, Gwan-Hyung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2008.10a
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    • pp.791-794
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    • 2008
  • 최근 홈오토메이션 시스템(Home Automation System) 즉, 가정 자동화 시스템에 대한 관심과 수요가 커지면서 이를 위한 네트워크 구축에 관한 여러 연구 및 개발이 활발히 이루어지고 있다. 홈오토메이션 시스템이란 가정에서 사용되는 여러 가전기기 및 센서장비를 이용하여 집 안의 기기를 제어함으로써 가정을 안전하게 관리하고, 사용자의 편의를 극대화하여 인간의 생활수준을 향상시키는 기술을 말한다. 본 논문에서는 Cypress사의 PSoC 기반으로 가정 내에서 사용할 수 있는 온도, 습도, 가스검출, 불꽃감지와 같은 여러 환경 센서 및 인체감지센서를 이용한 방범 센서 장치 구현방법을 제안하고, PSoC 기반의 WirelessUSB를 이용하여 센서 및 호스트 PC와의 네트워크 시스템을 구축한다.

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The transformation of the content of Dao-tong during the Tang and Song Dynasties (당송(唐宋) 시기 도통(道統) 내용의 전환 - 당말(唐末)에서 북송(北宋)시기 도의 전승 내용에 관한 담론을 중심으로 -)

  • Lim, Myung Hee
    • The Journal of Korean Philosophical History
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    • no.36
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    • pp.293-317
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    • 2013
  • The purpose of this paper is to examine the development of the content of Dao-tong during the Tang and Song Dynasties. This paper examines the transition of Dao-tong in the following three stages. First, Han-yu(韓愈) defined that Ren-Yi(仁義) is the content of Dao-tong. Second, Sun-fu(孫復) and other Confucian scholars in the Northern Song Dynasty stipulated that a broader meaning of Confucian Dao is the content of Dao-tong. Third, Qi-song(契嵩) and Dao-xue-jia(道學家) in the Northern Song Dynasty insisted that Zhi-Zhong(執中) should be a content of Dao-tong. This Confucian Orthodoxy is changed into the philosophical theory of human-nature and heart by Dao-xue-jia in the Northern Song Dynasty.

Beneficial effects of natural Jeju groundwaters on lipid metabolism in high-fat diet-induced hyperlipidemic rats

  • Wang, Yan-Chao;Lu, Jin-Miao;Jin, Hui-Zi;Ma, Ai-Niu;Zhang, Jin-Yang;Gong, Nian;Xiao, Qi;Zhu, Bin;Lv, Ying-Fang;Yu, Na;Zhang, Wei-Dong;Wang, Yong-Xiang
    • Nutrition Research and Practice
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    • v.8 no.2
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    • pp.165-171
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    • 2014
  • BACKGROUND: Groundwater is believed to possess many beneficial effects due to its natural source of various minerals. In this study, we examined the effects of natural Jeju groundwater S1 (Samdasoo$^{TM}$), S2 and S3 pumped up from different locations of Jeju Island, Korea, along with local tap water, on body weight gain, serum lipids and lipoproteins, and liver histopathology in high-fat diet-induced hyperlipidemic rats. MATERIALS/METHODS: Rats were randomly and equally divided into 6 groups. Different water samples were supplied to the hyperlipidemic rats as their daily drinking water and the widely-used anti-hyperlipidemic drug simvastatin was used as a positive control. Body weight, serum lipids and lipoproteins were measured weekly. Liver weight, liver index and liver histopathology were examined after the execution of the rats. RESULTS: After drinking Jeju groundwaters for two months, S2 but not S3 significantly reduced weight growth and serum triglycerides levels and increased high density lipoprotein-C (HDL-C) without affecting total cholesterol or LDL-C. S1 and particularly S2 significantly reduced the severity of liver hypertrophy and steatosis. All Groundwaters had much higher contents of vanadium (S3>S2>S1>>tap water) whereas S1 and S2 but not S3 markedly blocked autoxidation of ferrous ions. CONCLUSION: Jeju Groundwater S1 and particularly S2 exhibit protective effects against hyperlipidemia and fatty liver and hypothesize that the beneficial effect of Jeju Groundwaters may be contributed from blockade of autoxidation of ferrous ions rather than their high contents of vanadium.

Selection signature reveals genes associated with susceptibility loci affecting respiratory disease due to pleiotropic and hitchhiking effect in Chinese indigenous pigs

  • Xu, Zhong;Sun, Hao;Zhang, Zhe;Zhang, Cheng-Yue;Zhao, Qing-bo;Xiao, Qian;Olasege, Babatunde Shittu;Ma, Pei-Pei;Zhang, Xiang-Zhe;Wang, Qi-Shan;Pan, Yu-Chun
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.2
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    • pp.187-196
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    • 2020
  • Objective: Porcine respiratory disease is one of the most important health problems causing significant economic losses. To understand the genetic basis for susceptibility to swine enzootic pneumonia (EP) in pigs, we detected 102,809 single nucleotide polymorphisms in a total of 249 individuals based on genome-wide sequencing data. Methods: Genome comparison of susceptibility to swine EP in three pig breeds (Jinhua, Erhualian, and Meishan) with two western lines that are considered more resistant (Duroc and Landrace) using cross-population extended haplotype homozygosity and F-statistic (FST) statistical approaches identified 691 positively selected genes. Based on quantitative trait loci, gene ontology terms and literature search, we selected 14 candidate genes that have convincible biological functions associated with swine EP or human asthma. Results: Most of these genes were tested by several methods including transcription analysis and candidate genes association study. Among these genes: cytochrome P450 1A1 and catenin beta 1 (CTNNB1) are involved in fertility; transforming growth factor beta receptor 3 plays a role in meat quality traits; Wnt family member 2, CTNNB1 and transcription factor 7 take part in adipogenesis and fat deposition simultaneously; plasminogen activator, urokinase receptor (completely linked to AXL receptor tyrosine kinase, r2 = 1) plays an essential role in the successful ovulation of matured oocytes in pigs; colipase like 2 (strongly linked to SAM pointed domain containing ETS transcription factor, r2 = 0.848) is involved in male fertility. Conclusion: These adverse genes susceptible to swine EP may be selected while selecting for economic traits (especially reproduction traits) due to pleiotropic and hitchhiking effect of linked genes. Our study provided a completely new point of view to understand the genetic basis for susceptibility or resistance to swine EP in pigs thereby, provides insight for designing sustainable breed selection programs. Finally, the candidate genes are crucial due to their potential roles in respiratory diseases in a large number of species, including human.

Long-term Prognosis in Hepatocellular Carcinoma Patients after Hepatectomy

  • Zhou, Lei;Liu, Chang;Meng, Fan-Di;Qu, Kai;Tian, Feng;Tai, Ming-Hui;Wei, Ji-Chao;Wang, Rui-Tao
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.2
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    • pp.483-486
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    • 2012
  • Background: The hepatocellular carcinoma is very common in China. Our aim in this report was to investigate clinical and pathological factors based on the current decade data that could influence prognosis of HCC patients after hepatectomy. Methods: Between 2002 and 2009, all patients undergoing hepatectomy for HCC were followed up and reviewed retrospectively. Prognostic factors were studied by univariate and multivariate analysis, with Kaplan-Meier and Cox multivariate survival analyses. Results: Complete clinicopathologic and follow-up data were available for 114 patients. The estimated cumulative survival rates at 1, 3, and 5 yr were 84.6%, 60.2% and 51.8%, respectively. On univariate analysis, key prognostic factors were AFP level, GGT level, tumor size, number of tumors, portal vein invasion, liver cirrhosis status and TNM stage. In the multivariate analysis, tumor size, GGT level, liver cirrhosis status and portal vein invasion were significantly associated with patients' prognosis. Conclusion: Through follow-up of a relatively large cohort of Chinese patients, tumor size, GGT level, liver cirrhosis status, portal vein invasion were revealed as important factors for long-term survival after hepatectomy. Early diagnosis for tumor and the improvement of liver function before surgery are important ways to improve the prognosis.

Recent Developments in the Use of Intralesional Injections Keloid Treatment

  • Perdanasari, Aurelia Trisliana;Lazzeri, Davide;Su, Weijie;Xi, Wenjing;Zheng, Zhang;Ke, Li;Min, Peiru;Feng, Shaoqing;Zhang, Yixin;Persichetti, Paolo
    • Archives of Plastic Surgery
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    • v.41 no.6
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    • pp.620-629
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    • 2014
  • Keloid scars are often considered aesthetically unattractive and frustrating problems that occur following injuries. They cause functional and cosmetic deformities, displeasure, itching, pain, and psychological stress and possibly affect joint movement. The combination of these factors ultimately results in a compromised quality of life and diminished functional performance. Various methods have been implemented to improve keloid scars using both surgical and non-surgical approaches. However, it has proven to be a challenge to identify a universal treatment that can deliver optimal results for all types of scars. Through a PubMed search, we explored most of the literature that is available about the intralesional injection treatment of hypertrophic scars and keloids and highlights both current (corticosteroid, 5-fluorouracil, bleomycin, interferon, cryotherapy and verapamil) and future treatments (interleukin-10 and botulinum toxin type A). The reference lists of retrieved articles were also analysed. Information was gathered about the mechanism of each injection treatment, its benefits and associated adverse reactions, and possible strategies to address adverse reactions to provide reliable guidelines for determining the optimal treatment for particular types of keloid scars. This article will benefit practitioners by outlining evidence-based treatment strategies using intralesional injections for patients with hypertrophic scars and keloids.

Electromagnetic Field Exposure and Male Breast Cancer Risk: A Meta-analysis of 18 Studies

  • Sun, Jing-Wen;Li, Xiao-Rong;Gao, Hong-Yu;Yin, Jie-Yun;Qin, Qin;Nie, Shao-Fa;Wei, Sheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.523-528
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    • 2013
  • Background: The possibility that electromagnetic fields (EMF) exposure may increase male breast cancer risk has been discussed for a long time. However, arguments have been presented that studies limited by poor quality could have led to statistically significant results by chance or bias. Moreover, data fo the last 10 years have not been systematically summarized. Methods and Results: To confirm any possible association, a meta-analysis was performed by a systematic search strategy. Totals of 7 case-control and 11 cohort studies was identified and pooled ORs with 95% CIs were used as the principal outcome measures. Data from these studies were extracted with a standard meta-analysis procedure and grouped in relation to study design, cut-off point, exposure assessment method, adjustment and exposure model. A statistical significant increased risk of male breast cancer with EMF exposure was defined (pooled ORs = 1.32, 95% CI = 1.14-1.52, P < 0.001), and subgroup analyses also showed similar results. Conclusions: This meta-analysis suggests that EMF exposure may be associated with the increase risk of male breast cancer despite the arguments raised.