• Journal of the Korean Data and Information Science Society
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• v.8 no.2
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• pp.111-118
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• 1997

Adding a noise tolerance factor to the Relaxation learning algorithm in Hop-field network improves noise tolerance without effecting storage capacity. The new algorithm is called the Pseudo-Relaxation algorithm, and the convergence of the algorithm has been proved. It is also shown that the noise tolerance factor does not effect learning speed.

• Journal of Korean Elementary Science Education
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• v.36 no.4
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• pp.439-446
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• 2017

The purpose of this study was to compare Grit, failure tolerance and psychological well-being between elementary science gifted and general students. The subjects of this study were 48 science gifted students and 70 general students in the 5th and 6th grade of elementary school in Gyeonggi province. The results of this study were as follows: First, Grit, failure tolerance and psychological well-being of science gifted students were higher than those of the general students, there was a statistically significant difference. Second, science gifted students showed higher correlation between grit and failure tolerance, grit and psychological well-being than general students. Grit of science gifted students had a positive correlation with all sub-factors of academic failure tolerance and psychological well-being. In general students, there was a positive correlation with all sub-factors of Grit, academic failure tolerance, and psychological well-being except for the emotion sub-factor of academic failure tolerance. Thirdly, as a result of the regression analysis on the elements of failure tolerance affecting the Grit, science gifted students showed emotional factor but general students had behavioral factors. Also, as a sub-factor of psychological well-being on Grit, both science gifted and general students showed autonomy.

• Journal of Auto-vehicle Safety Association
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• v.6 no.2
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• pp.43-48
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• 2014

The flexible pedestrian legform impactor(Flex-PLI) consisting of a flexible femur and tibia will be tested for pedestrian protection by global technical regulation(GTR) within the next couple of years as a replacement for the existing transport research laboratory(TRL) legform impactor. In this study, a computer aided engineering(CAE) model was used to perform the effect analysis of each injury with regard to the changes in tolerance factors with the baseline results without tolerance. The tolerance factors were the height of impactor from ground reference line, initial velocity of impactor and rotation of impactor.

• Journal of the Korea Institute of Military Science and Technology
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• v.16 no.2
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• pp.154-159
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• 2013

Alignment tolerance for EO/IR airborne camera using common optic is an important factor in stabilization accuracy and geo-pointing accuracy. Before airborne camera is mounted on the aircraft, defining alignment tolerance and verification of it is essential in production as well as research and development. In this paper we establish basic concept on the definition and elements of alignment tolerance for airborne camera and propose how to measure each of those elements. Components and the measurement sequence of alignment tolerance are as follows: 1) tolerance of alignment between EO and IR LOS. 2) tolerance of sensor alignment. 3) tolerance of position reporting accuracy. 4) tolerance of mount alignment

• The Korean Journal of Pain
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• v.37 no.3
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• pp.233-246
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• 2024

Background: Ferrostatin-1 and liproxstatin-1, both ferroptosis inhibitors, protect cells. Liproxstatin-1 decreases morphine tolerance. Yet, ferrostatin-1's effect on morphine tolerance remains unexplored. This study aimed to evaluate the influence of ferrostatin-1 on the advancement of morphine tolerance and understand the underlying mechanisms in male rats. Methods: This experiment involved 36 adult male Wistar albino rats with an average weight ranging from 220 to 260 g. These rats were categorized into six groups: Control, single dose ferrostatin-1, single dose morphine, single dose ferrostatin-1 + morphine, morphine tolerance (twice daily for five days), and ferrostatin-1 + morphine tolerance (twice daily for five days). The antinociceptive action was evaluated using both the hot plate and tail-flick tests. After completing the analgesic tests, tissue samples were gathered from the dorsal root ganglia (DRG) for subsequent analysis. The levels of glutathione, glutathione peroxidase 4 (GPX4), and nuclear factor erythroid 2-related factor 2 (Nrf2), along with the measurements of total oxidant status (TOS) and total antioxidant status (TAS), were assessed in the tissues of the DRG. Results: After tolerance development, the administration of ferrostatin-1 resulted in a significant decrease in morphine tolerance (P < 0.001). Additionally, ferrostatin-1 treatment led to elevated levels of glutathione, GPX4, Nrf2, and TOS (P < 0.001), while simultaneously causing a decrease in TAS levels (P < 0.001). Conclusions: The study found that ferrostatin-1 can reduce morphine tolerance by suppressing ferroptosis and reducing oxidative stress in DRG neurons, suggesting it as a potential therapy for preventing morphine tolerance.

• Biomedical Science Letters
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• v.23 no.3
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• pp.175-184
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• 2017

Cholera toxin (CT) is an ADP-ribosylating bacterial exotoxin that has been used as an adjuvant in animal studies of oral immunization. The mechanisms of mucosal immunogenicity and adjuvanticity of CT remain to be established. In this study, we investigated the role of indoleamine 2,3-dioxygenase (IDO), which participates in the induction of immune tolerance, in CT-mediated breakdown of oral tolerance. When IDO-deficient ($IDO^{-/-}$) mice and their littermates were given oral ovalbumin, significant changes in antibody responses, footpad swelling and $CD4^+$ T cell proliferation were not observed in $IDO^{-/-}$ mice. Feeding of CT decreased IDO expression in mesenteric lymph nodes (MLN) and Peyer's patch (PP). CT-induced downregulation of IDO expression was reversed by inhibitors of nuclear factor-kappa B (NF-${\kappa}B$), pyrrolidine dithiocarbamate and p50 small interfering RNA. IDO expression was downregulated by the NF-${\kappa}B$ inducers lipopolysaccharide and tumor necrosis factor-${\alpha}$. CT dampened IDO activity and mRNA expression in dendritic cells from MLN and PP. These data indicate that CT disrupts oral tolerance by activating NF-${\kappa}B$, which in turn downregulates IDO expression. This study betters the understanding of the molecular mechanism underlying CT-mediated abrogation of oral tolerance.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.50 no.1
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• pp.8-13
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• 2001

LMS algorithm has been used for plant identifier and noise cancellation. This algorithm has been researched for performance enhancement of filtering. The design and development of a reliable system has been becoming a key issue in industry field because the reliability of a system is considered as an important factor to perform the system's function successfully. And the computing with reliability and fault tolerance is a important factor in the case of aviation, system communication, and nuclear plant. This paper presents design of reliable adaptive filter with fault tolerance. Generally, redundancy is used for reliability. In this case it needs computing or circuit for voting mechanism, or fault detection. Therefore it has simple computing, and practicality for application. And in this paper, reliability of adaptive filter is analyzed. The effectiveness of the proposed adaptive filter is demonstrated to the case studies of plant identifier and noise cancellation by using DSP.

• Journal of The Korean Society of Grassland and Forage Science
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• v.43 no.1
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• pp.42-49
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• 2023

The plant-specific NAC transcription factors control various biological processes, including plant development and stress responses. We have isolated an ANAC032 gene, one of the NAC transcription factor family, which was highly activated by multi-abiotic stresses, including high salt and drought in Arabidopsis. Here, we generated transgenic plants constitutively expressing ANAC032 and its knockout to identify the functional roles of ANAC032 in Arabidopsis under abiotic stress responses. The ANAC032-overexpressing plants showed enhanced tolerance to salinity and drought stresses. The anac032 knockout mutants were observed no significant changes under the high salt and drought conditions. We also monitored the expression of high salt and drought stress-responsive genes in the ANAC032 transgenic plants and anac032 mutant. The ANAC032 overexpression upregulated the expression of stress-responsive genes, RD29A and ERD10, under the stresses. Thus, our data identify that transcription factor ANAC032 plays as an enhancer for salinity and drought tolerance through the upregulation of stress-responsive genes and provides useful genetic traits for generating multi-abiotic stress-tolerant forage crops.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.39 no.4
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• pp.306-313
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• 2011

The damage tolerance analysis is required to guarantee the structural safety and the reliability for aircraft components. The damage tolerance method, which evaluate the life considering the initial crack, considers a fatigue design model of the aircraft main structure. The fatigue crack growth life should be calculated in damage tolerance analysis and the inspection time to define the replacement cycle. In this paper, the damage tolerance analysis is performed for a turbine wheel which has complex geometry. The equation of the stress intensity factor for complex geometry is hard to know, so that they are usually processed by finite element analysis which takes long time. To solve this problem, the stress intensity factors at specified crack are obtained by the FEA and the crack growth life is evaluated using the surrogate model which is generated by the regression analysis of the FEA data. From the results, the efficiency of the crack growth life calculation and the damage tolerance analysis could be increased by taking the surrogate model.

• Journal of Microbiology and Biotechnology
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• v.7 no.5
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• pp.356-359
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• 1997

To study the relationship between oxygen tolerance and enzyme activity in the oxygen metabolism of bifidobacteria, the activities of catalase, superoxide dismutase (SOD), NADH oxidase and NADH peroxidase from six typical bifidobacteria and other bacteria were assayed by spectrophotometry. Catalase activity was hardly detected in any of the bifidobacteria tested. SOD activity was detected in every species including the Clostridium species. In particular SOD activity was notably high in the aerosensitive Bifidobacterium adolescentis. This fact indicates that SOD activity is not a critical factor to ensure aerotolerance. Aerosensitive B. adolescentis showed very low NADH oxidative enzyme activity whereas other aerotolerant bifidobacteria exhibited considerable activity for the enzymes. It seems that detoxification of $H_2O_2$ by NADH oxidative enzymes might be an important factor in improving for aerotolerant bifidobacteria survival rates in an oxygen environment.