• Title/Summary/Keyword: ToFD

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Numerical Study of Fluidic Device in APR1400 Using Free-Surface Model (자유수면모델을 활용한 APR1400 유량조절장치의 수치해석 연구)

  • Lim, Sang-Gyu;You, Sung-Chang;Kim, Han-Gon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.7
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    • pp.767-774
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    • 2012
  • A fluidic device (FD) has been adopted in the safety injection tanks (SITs) of APR1400. A flow control mechanism of the FD was used to vary the flow regime in the vortex chamber corresponding to the SITs water level. The flow regime in the vortex chamber has a different pressure loss from low to high in accordance with the SITs water level. Nitrogen at the top of the SIT could be released owing to inertia of discharge flow when changing from a high flow rate to a low flow rate. This phenomenon is important to design improvement perspective because it can affect the performance of the FD. This paper shows a result of a preliminary numerical study to obtain the transient data related to air release in the flow turn-down period using a two-fluid free-surface model provided from ANSYS CFX 13.0. In conclusion, there is no significant effect on the performance of the FD, though a small quantity of air is released during the flow turn-down period.

TWO CASES OF MASSIVE CRANIOFACIAL FIBROUS DYSPLASIA (광범위한 두개안면부 섬유성골이형성증의 치험 2례)

  • Kim, Jong-Ryoul;Chung, Gi-Deon;Kim, Hong-Sik;Kim, Ki-Won
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.1
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    • pp.61-68
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    • 1996
  • In Fibrous dysplasia(FD) of the jaws, the majority of cases can await the cessation of growth before surgical intervention, and it seems prudent to delay surgery whenever possible until growth has ceased. In craniofacial FD, however, the dangers of dystopia, dystopia and loss of vision may require early surgery to prevent or control cranio-orbital complications. Delaying surgery in those circumstances may be significantly detrimental to such patients. Conservative surgical management of FD is widely practised and we advocate an extension to this conservative treatment by combining surgical recontouring with appropriate osteotomies if indicated, to achieve an optimal esthetic and functional results in craniofacial FD. One case will be presented to illustrate the feasiblility of such combined treatment, to report the uneventful healing of osteotomies in the FD of the jaws, and to demonstrate the use of titanium miniplate fixation in dysplastic bone. The other case had expansile disease of the left facial and fronto-temporal bones and osteolytic change left mandible. This patient complained of severe spontaneous bleeding of left mandibular premolar area and it was suspected as central hemangioma of the left mandible and craniofacial FD. Angiogram disclosed generalized dilation of the external carotid artery and its branches, especially terminal branches of the left facial and inferior alveolar arteries. But no specific abnormalities, such as A-V shunt, venous lake, or early venous drainage, was seen. So it was diagnosed craniofacial FD with hypercellularity and generalized bony recontouring was performed via coronal and transoral approaches.

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A Clinical Study on the Relationship between Functional Dyspepsia (FD) and Biosignals from Heart Rate Variability (HRV) and Yangdorak Diagnosis (기능성 소화불량증과 심박변이도 및 양도락과의 상관성 연구)

  • Yoon, Seung-Woo;Park, Jae-Woo
    • The Journal of Korean Medicine
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    • v.28 no.2 s.70
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    • pp.80-92
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    • 2007
  • Objectives : Functional dyspepsia (FD) is one of the most common gastrointestinal diseases. Nevertheless, there are many unknown mechanisms of autonomic functioning in FD patients. This study was designed to investigate the relationship between FD and biosignals from heart rate variability (HRV) and Yangdorak diagnosis. Methods : 32 patients (22 female, 10 male; mean age 40) and 32 healthy volunteers (21 female, 11 malemean; age 38) participated in this study. First gastrointestinal symptoms rating scale (GSRS) was assessed by questionnaires in both groups to evaluate the types of gastrointestinal symptoms. Second, HRV and Yangdorak diagnosis were measured in both groups. Results : 1. The FD group in this study mainly had the complaint of 'bloating' symptoms. 2. There was statistically no significant difference between Yangdorak (total average and 24 acupoints) and HRV values except logarithmic low-frequency band (lnLF) and total power (TP) in frequency domain. 3. There was statistically no significant relationship between HRV and Yangdorak in either group. However, most Yangdorak values were positively related with some HRV values (low-frequency, low-frequency/high-frequency ratio and high-frequency, etc) in the control group. Conclusions : FD patients had relatively lesser sympathetic domain than healthy subjects, indicated by decreased lnLF and TP. Particularly, there were positive relationships and significant differences between Yangdorak and HRV in young healthy subjects. This suggests that biosignals from HRV may be a useful method that can differentiate FD from healthy state in those of young age.

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Clinical Characteristics of Patients with Functional Dyspepsia Diagnosed as Food Retention (식적으로 진단된 기능성소화불량 환자의 임상적 특성)

  • Jeong, Hae-in;Lee, Hanul;Lee, Hyun-jin;Cho, Yun-jae;Han, Aram;Keum, Chang-yul;Ha, Na-yeon;Kim, Jin-sung
    • The Journal of Internal Korean Medicine
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    • v.42 no.6
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    • pp.1173-1183
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    • 2021
  • Objectives: This study investigated the clinical characteristics of functional dyspepsia (FD) patients with food retention (FR) in regard to the parameters of cutaneous electrogastrography (EGG), Ryodoraku, and heart rate variability (HRV). Methods: This study reviewed the clinical records of 33 FD patients with FR who filled out the FR Questionnaire for FD (FRQ-FD) and underwent EGG for six months from March 1st, 2021. We summarized the clinical characteristics of FD patients with FR and analyzed the correlation between FRQ-FD score and parameters of EGG, Ryodoraku, and HRV. Results: FRQ-FD scores had a positive correlation with percentage of postprandial bradygastria and negative correlation with power ratio, detected on Channel 2, 3 of EGG. The total average (TA) Ryodoraku score was lower, and the high frequency density (HF) of HRV was higher than the normal value. Conclusions: The results of this study suggest that clinicians can use EGG, Ryodoraku, and HRV to increase the accuracy of diagnosing FR in FD patients.

The Analysis of Light Coupling and Propagation for The Composite Fiber-Dielectric Slab with a Conductor Cladding Using The Three Dimensional Finite Difference-Beam Propagating Method (3차원 FD-BPM을 이용한 측면 연마된 광섬유와 완전도체면 아래의 유전체 사이에서의 결합과 전파 특성의 해석)

  • 권광희;송재원;이동호
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.9A
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    • pp.754-762
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    • 2003
  • The coupled and propagated property of the composite side-polished fiber and infinite planar waveguide with conductor cladding (PWGCC) is presented by using the 3-D finite difference beam propagating method (FD-BPM) in according to the variety of refractive indexes between the fiber and the infinite planar waveguide. It is also introduced for the technique to be applied at and consisted of the analysis domain of 3-D FD-BPM for the coupling between the side-polished fiber and PWG. It is also compared the properties of coupling between the side-polished fiber and PWGCC with them of the general symmetric and asymmetric PWG without perfect conductor (PEC), which has been investigated by many researcher.

Investigation on the Functional Properties of Chestnut Flours and Their Potential Utilization in Low-fat Cookies

  • Inkaya, Ayse N.;Gocmen, Duygu;Ozturk, Serpil;Koksel, Hamit
    • Food Science and Biotechnology
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    • v.18 no.6
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    • pp.1404-1410
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    • 2009
  • Chestnut flours (CFs) were produced from 3 chestnut samples (Aydin, Kutahya, and Bursa) by 2 different methods (boiled and oven-dried: BOD-CF and freeze-dried: FD-CF). Functional properties and effects of CF addition (10, 20, and 30%) on the qualities of regular and low-fat cookie were investigated. The freeze drying significantly increased water solubility of CFs but decreased their water binding capacity. The emulsion capacity and stability of FD-CFs were higher than those of BOD-CFs. At pH 4, 6, 8, and 10 FD-CFs had better gelation properties. Spread ratio (SR) values of BOD-CF supplemented regular or low-fat cookies decreased with increasing CF levels. Hardness values of CF supplemented regular cookies were generally lower compared to control. SR and hardness values of FD-CF supplemented cookies were higher than those of BOD-CF supplemented ones. Surface colors of the cookies were darker with FD-CF addition as compared to BODCF addition. In low-fat cookies, the sample supplemented with 10% Kutahya FD-CF had the highest taste-flavor value. FDCF supplementation generally resulted in higher appearance and taste-flavor scores than BOD-CF supplementation in cookies.

Status of High Risk Group Fabry Disease Screening in Korea by Measuring Globotriacocylceramide in Body Fluid using Electrospray-MS/MS (탠덤매스에의한 체액 중 Globotriaocylceramide(Gb-3)의 측정을 이용한 한국인 고 위험도군에서의 파브리병 스크리닝)

  • Yoon, Hye-Ran
    • YAKHAK HOEJI
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    • v.55 no.1
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    • pp.56-63
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    • 2011
  • Fabry disease (FD) is an X-linked inborn error of glycoshpingolipid metabolism resulting from mutation in the enzyme ${\alpha}$-galactosidase A gene. The disease is an X-linked lipid storage disorder and the lack of ${\alpha}$-Gal A causes an intracellular accumulation of glycosphingolipids, mainly globotriaosylceramide (Gb-3). Measurement of Gb-3 in plasma has clinical importance for monitoring after enzyme replacement therapy for confirmed FD patients. Using electrospray ionization MS/MS we had developed, a simple, rapid, and highly sensitive analytical method for Gb-3 in plasma was used for the purpose of screening FD among high risk groups in Korean population. To date, no comprehensive results for FD screening have been performed and reported in Korea. We screened 1,100 outpatients from 13 hospitals (including clinics) to assess the incidence of FD among patients in high risk groups. For patients with borderline level amount of Gb-3, we repeated Gb-3 or performing complementary or confirmative assay with ${\alpha}$-Gal A activity and DNA mutaion analysis for confirmation diagnosis. Of 1,100 we diagnosed 3 FD with 2 classical type and 1 carrier (0.27%).

Clinical Application of Botulinum Toxin to Functional Dysphonia (기능성 음성장애에서 보툴리늄 독소의 임상적 적용)

  • Kim, Han Su
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.30 no.1
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    • pp.12-14
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    • 2019
  • Functional dysphonia (FD) is a disease entity which includes various voice disorders in the absence of structural or neurologic laryngeal pathology. Muscle tension dysphonia (MTD), psychogenic dysphonia are representative FD with completely different pathogenesis. Therefore there is no standard treatment modality for FD, the first step of treatment of FD is differentiating patient's voice symptoms from other organic voice disorders and other functional voice problems. MTD is a functional voice disorder caused by hyperfunction of intrinsic and extrinsic laryngeal musculature. Symptoms include increased vocal effort, roughness, fatigue and odynophonia. First line for MTD is indirect or direct voice therapy. Unfortunately, many patients with MTD improve with voice therapy alone. For these patients, various modalities tried; lidocaine application, surgical excision of the false vocal folds, and botulinum toxin injection, etc. Botulinum toxin injections are widely used in the field of otolaryngology, especially for spasmodic dysphonia. However, its use in FD or MTD has only been described in few case reports. The aim of this lecture is to evaluate the feasibility of botulinum toxin injection for FD, especially MTD.

Anti-Inflammatory Effect of Freeze-Dried Broccoli Sprout Powder with Antioxidant Activity in RAW264.7 Cells

  • Hyun Jung Lim;Jong Soon Choi
    • Journal of the Korean Society of Food Culture
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    • v.39 no.3
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    • pp.156-165
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    • 2024
  • Sprout products, such as broccoli, alfalfa, and cabbage, have positive health effects. Thus far, sprout foods have attracted attention owing to their good bioavailability. In particular, young broccoli sprouts exhibit anti-inflammatory, antioxidant, and anti-cancer effects. They contain 100 times more chemoprotective substances than adult broccoli. This study examined the anti-inflammatory effects of freeze-dried young sprout broccoli (FD-YB) in vitro using RAW264.7 macrophage cells. The FD-YB powder antioxidant ability test showed that the radical-scavenging activity and superoxide dismutase enzyme activity increased in a dose-dependent manner. In addition, FD-YB was not cytotoxic to RAW264.7 cells, and nitric oxide production decreased after the FD-YB treatment of lipopolysaccharide-stimulated RAW264.7 cells in a dose-dependent manner. Furthermore, FD-YB significantly decreased the expression of inflammation-related proteins (Cyclooxygenase-2, Inducible nitric oxide synthase, and Prostaglandin E Synthase 2) and cytokines (Tumor necrosis factor-α and Interleukin-6). In conclusion, FD-YB can be a potential nutraceutical for preventing and regulating excessive immune responses during inflammation.

Comparison and Performance analysis of Wavelet OFDM system and FD-OFDM (웨이블릿 OFDM 시스템과 FD-OFDM 시스템 성능 비교 분석)

  • Lee, Junseo;Kim, Ji-Hoon;Kim, Whanwoo
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.7
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    • pp.34-42
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    • 2013
  • In this paper, we compare the performance of wavelet OFDM (Orthogonal Frequency Division Multiplexing) and FD-OFDM(Frequency diversity OFDM) system with conventional OFDM system. Wavelet OFDM system uses wavelet transform rather than Fourier transform and contains intermediate characteristics of CDM (Code Division Multiplexing) and OFDM. In wavelet OFDM system, inter-symbol interference (ISI) can be suppressed effectively and adjacent channel interference can be also minimized well. In FD-OFDM system, each parallel branch symbol is multiplied by the orthogonal sequence and distributed into all sub-carriers. Then, each sub-carrier transmits information composed of the symbol components of all parallel branches in the given frame. FD-OFDM contains the frequency diversity characteristic and, therefore, FD-OFDM can be robust to the narrowband interference. For the comparison among different systems, BER (Bit-Error Rate) performances are evaluated in the presence of narrow-band interference and a harmonic noise channel. From the evaluation results, compared to the conventional OFDM, wavelet OFDM and FD-OFDM shows better robustness against the interference and, especially, wavelet OFDM is the most robust in harmonic noise channel.