• Journal of the Korean Society of Radiology
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• v.8 no.1
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• pp.11-18
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• 2014

The purpose study is to investigate the correlation between cardiovascular symptoms and factors in police officers, to provide basic data for a systematic and effective resource management of radiation workers in the future. This study was conducted on police officers who visited the national police hospital and who underwent 201Tl-SPECT for the diagnosis of cardiovascular diseases. In study result, smokers than non-smokers 1.80 times higher cardiovascular disease. Beside, person with hypertension than those who do not have hypertension 1.63 times higher cardiovascular disease. And, the probability of cerebrovascular disease was 1.82 times higher in patients with a low HDL level.

• The Korean Journal of Nuclear Medicine
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• v.34 no.4
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• pp.276-284
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• 2000

Purpose: We investigated the operative outcome after bypass surgery in patients selected using viability criteria on F-18 FDG PET. Materials and Methods: Rest-24hr delay redistribution imaging of Tl-201 SPECT and F-18 FDG PET were performed in 11 patients. Seven of these 11 patients (6 men, 1 woman) were evaluated to have viable myocardium by F-18 FDG PET. Changes in symptoms and left ventricular ejection fraction (LVEF) after operation were evaluated. Results: In seven of 11 patients, a significant amount of viable myocardium was found on F-18 FDG PET and Tl-201 SPECT. Severity of both chest pain and dyspnea improved markedly in all patients. Mean LVEF improved from 22% to 32%. Conclusion: F-18 FDG PET could be used to select the patients who will benefit from coronary artery bypass surgery.

• Journal of Yeungnam Medical Science
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• v.20 no.2
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• pp.117-128
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• 2003

Thallium-201 scintigraphy is used to discriminate the malignant bone tumor from the benign by qualitatively and quantitatively, and to predict the response of preoperative chemotherapy in osteosarcoma, by comparing the changes of thallium uptake ratio after chemotherapy to the tumor necrosis ratio. Thallium-201 scintigraphy scan should be done prior to surgical biopsy. PICKER Prism 2000 gamma camera with high resolution parallel hole collimator is usually used for scanning. The patient is injected with 2-3mCi of Tl-201 and the early phase is checked in 30 minutes and delayed phase in 3 hours. The scan images are visually evaluated by a blinded nuclear medicine physician. We could evaluate true positive, true negative, false positive and false negative by the comparison of results with those of biopsy, and calculate positive and negative predictive value(%), sensitivity(%), specificity(%) and diagnostic accuracy(%). For the quantitative analysis of thallium uptake, we drew the region of interest on the tumor side and contralateral normal side as mirror image, and calculated the uptake ratio with dividing the amount of gamma count in tumor side by normal side. We could calculate the percent changes of thallium uptake ratio in early and delayed phase, and compare them to the ratio of tumor necrosis. Thallium-201 scintigraphy proved as useful imaging study to discriminate malignant bone tumor from benign, but had exception in giant cell tumor and low grade malignant bone tumors. We can use T1-201 scan to differentiate the benign from the malignant tumor, and to evaluate the response of preoperative chemotherapy or radiotherapy, and to determine the residual tumor or local recurrence. For the better result, we need to have a more detail information about false positive cases and a more objective and quantitative reading technique.

• Nuclear Medicine and Molecular Imaging
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• v.41 no.5
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• pp.364-372
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• 2007

Purpose: This study was designed to investigate the cellular uptake of various tumor imaging radiopharmaceuticals in human breast cancer cells before and after paclitaxel exposure considering viable cell number. Materials and Methods: F-18-fluorodeoxyglucose, C-11-methionine, Tl-201, Tc-99m-MIBI, and Tc-99m-tetrofosmin were used to evaluate the cellular uptake in MCF-7 cells. MCF-7 cells were cultured in multi-well plates. Wells were divided into DMSO exposure control group, and paclitaxel exposure group. The exposure durations of paclitaxel with 10 nM or 100 nM were 2 h, 6 h, 12 h, 24 h, and 48 h. Results: Viable cell fraction was reduced as the concentration and exposure time of paclitaxel increased. After 10 nM paclitaxel exposure, the cellular uptake of all 5 radiopharmaceuticals was not reduced significantly, irrespective of exposure time and viable cell fraction. After 100 nM paclitaxel exposure, the cellular uptake of all 5 radiopharmaceuticals was enhanced significantly irrespective of viable cell fraction. The peak uptake was observed in experimental groups with paclitaxel exposure for 6 to 48 h according the type of radiopharmaceutical. When the cellular uptake was adjusted for the viable cell fraction and cell count, the peak cellular uptake was observed in experimental groups with paclitaxel exposure for 48 h, irrespective of the type of radiopharmaceutical. Conclusion: The cellular uptake of F-18-fluorodeoxyglucose, C-11-methionine, Tl-201, Tc-99m-MIBI, and Tc-99m-tetrofosmin did not reflect viable cell number in MCF-7 cells after paclitaxel exposure for up to 48 h.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.51 no.3
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• pp.302-311
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• 2015

A series of field tests to estimate the size selectivity of monofilament and multifilament gill net for marbled sole, Pleuronectes yokohamae, were carried out 12 times with five different mesh sizes (86.6, 101.0, 121.2, 137.7 and 151.5mm) in the western sea of Korea from 2007 to 2009. The master selection curve was estimated by the extended Kitahara's method. The total number of catch species was 23 and that of catch was 1,688 in the field tests. Marbled sole of total catch was 1,150 with 68.1 percent. In the monofilament trammel net, the optimum value of total length (TL) per mesh size (m) for 1.0 of retention probability was estimated 0.280 and the values of TL/m were estimated to be 0.187, 0.201, 0.210, 0.218 and 0.226 when the retention probability were 0.1, 0.2, 0.3, 0.4 and 0.5, respectively. In the multifilament trammel net, the optimum value of TL/m for 1.0 of retention probability was estimated 0.307 and the values of TL/m were estimated to be 0.195, 0.211, 0.222, 0.232 and 0.241 when the retention probability were 0.1, 0.2, 0.3, 0.4 and 0.5, respectively.

• 대한핵의학회:학술대회논문집
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• 1995.05a
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• pp.206-206
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• 1995

• 대한핵의학회:학술대회논문집
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• 2001.11a
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• pp.41.1-41.1
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• 2001

• 대한핵의학회:학술대회논문집
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• 1998.11a
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• pp.31.1-31.1
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• 1998

• Journal of The Korean Radiological Technologist Association
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• v.29 no.1
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• pp.67-71
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• 2003

Purpose : 201Tl Myocardium SPECT Test uses $180^{\circ}$ reorganization due to the energy diffusion decrease by backbone and muscles, but $^{99m}Tc$-Tetrofosmin Myocardium SPECT Test can get more information by $360^{\circ}$

• The Korean Journal of Nuclear Medicine
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• v.26 no.1
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• pp.65-71
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• 1992

Myocardial perfusion imaging with $^{201}Tl-chloride$ following exercise or vasodilator-induced hyperemia has been effective in detecting the presence of coronary artery disease. An increased lung uptake of thallium has been reported as a sensitive marker of severe and extensive coronary artery disease and associated with poor prognosis. Thallium has also been noted to concentrate in a variety of malignant lesions. We report 5 cases of extracardiac uptake of thallium during myocardial perfusion scan with pharmacologic vasodilation. Accumulation of thallium was found in the lesions of a breast cancer, a lung cancer, a Castleman's disease and 2 cases of thymoma. We believe that the presence of focal extracardiac uptake of thallium during myocardial perfusion scan should suggest the need for further clinical evaluation to detect the tumor and must differentiate the increased lung uptake of thallium due to left ventricular dysfunction in coronary artery disease.