Extracardiac Uptake of Thallium-201 during Myocardial Perfusion Imaging with Pharmaeologic Vasodilation

심근관류 스캔중에 나타난 Thallium-201의 심장외 국소적 섭취

  • Choi, Chung-Il (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Kwak, Dong-Suk (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Chung, Byung-Cheon (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Park, Moo-Keun (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Lee, Jae-Tae (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Lee, Kyu-Bo (Department of Nuclear Medicine, School of Medicine, Kyungpook National University)
  • 최정일 (경북대학교 의과대학 핵의학교실) ;
  • 곽동석 (경북대학교 의과대학 핵의학교실) ;
  • 정병천 (경북대학교 의과대학 핵의학교실) ;
  • 박무근 (경북대학교 의과대학 핵의학교실) ;
  • 이재태 (경북대학교 의과대학 핵의학교실) ;
  • 이규보 (경북대학교 의과대학 핵의학교실)
  • Published : 1992.05.31

Abstract

Myocardial perfusion imaging with $^{201}Tl-chloride$ following exercise or vasodilator-induced hyperemia has been effective in detecting the presence of coronary artery disease. An increased lung uptake of thallium has been reported as a sensitive marker of severe and extensive coronary artery disease and associated with poor prognosis. Thallium has also been noted to concentrate in a variety of malignant lesions. We report 5 cases of extracardiac uptake of thallium during myocardial perfusion scan with pharmacologic vasodilation. Accumulation of thallium was found in the lesions of a breast cancer, a lung cancer, a Castleman's disease and 2 cases of thymoma. We believe that the presence of focal extracardiac uptake of thallium during myocardial perfusion scan should suggest the need for further clinical evaluation to detect the tumor and must differentiate the increased lung uptake of thallium due to left ventricular dysfunction in coronary artery disease.

Keywords