• Title/Summary/Keyword: Tissue Phantom

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Development of the Reference Korean Female Voxel Phantom (한국인 기준여성 체적소형 모의체 개발)

  • Ham, Bo-Kyoung;Cho, Kun-Woo;Yeom, Yoen-Soo;Jeong, Jong-Hwi;Kim, Chan-Hyeong;Han, Min-Cheol
    • Journal of Radiation Protection and Research
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    • v.37 no.1
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    • pp.41-49
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    • 2012
  • The objective of this study is for development of the reference Korean female phantom, HDRK-Woman. The phantom was constructed by adjusting a Korean woman voxel phantom to the Reference Korean data. The Korean woman phantom had been developed based on the high-resolution color slice images obtained from an adult Korean female cadaver. There were a total of 39 organs including the 27 organs specified in ICRP 103 for effective dose calculation. The voxel resolution of the phantom was $1.976{\times}1.976{\times}2.0619\;mm^3$ and the voxel array size is $261{\times}109{\times}825$ in the x, y and z directions. Then, the voxel resolution was changed to $2.0351{\times}2.0351{\times}2.0747\;mm^3$ for adjustment of the height and total bone mass of the phantom to the Reference Korean data. Finally, the internal organs and tissue were adjusted using in-house software program developed for 3D volume adjustment of the organs and tissue. The effective dose values of HDRK phantoms were calculated for broad parallel photon beams using MCNPX Monte Carlo code and compared with those of ICRP phantoms.

Parameter Estimation of Tissue Structure Characteristics in Ultrasound Measurement (초음파를 이용한 조직구조 특성변수의 측정)

  • 곽철은;김종원
    • Journal of Biomedical Engineering Research
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    • v.7 no.1
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    • pp.41-44
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    • 1986
  • The objective of tissue characterization is to provide quantitative information about the physical state of tissue interrogated by an ultrasound beam. In the computer simulation, it was found that the echoes were composed of the interferences of the ultrasonic waves reflected from both sides of the thin object, and could be separated by the spectral correlation method. Also, the phantom study demonstrates that thickness of the thin acryl layer beyond the resolution of common ultrasonic imaging systems can be measured- using this method.

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Analysis of Properties and Phantom Design Based on Plastic Hardener and Softener for Ultrasonic Imaging (초음파 영상용 플라스틱 기반의 팬텀제작 및 특성 분석)

  • Lee, G.J.;Park, D.H.;Shin, T.M.;Seo, J.B.
    • Journal of Biomedical Engineering Research
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    • v.29 no.4
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    • pp.302-306
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    • 2008
  • Plastic hardener and softener based ultrasound phantoms were made in various constitutions and their acoustic properties were measured. Speed of sound is approximately $1.4\;mm/{\mu}sec$ in all the phantoms, which is about 7% less than that of in soft tissue. Attenuation coefficient is strongly dependent on the ratio between hardener and softener. In order to achieve the tissue level attenuation (0.5 dB/cm/MHz), 60% of hardener or less is required. The synthesized phantoms can be preserved for more than 6 months without structural degradation.

Gadolinium-Chlorin is Potentially a New Tumor Specific MRI Contrast Agent

  • Kim Jong-Ki;Kim Dong-Myung;Kang Min-Suk;Kim Hae-Kyung;Kim Jeong-Sook;Yu Eun-Kyung;Jeong Jin-Hyun
    • Archives of Pharmacal Research
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    • v.29 no.3
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    • pp.188-190
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    • 2006
  • In this study, a newly-synthesized metalloporphyrin, Gd-chlorin (PB Chlorin), was investigated by using a simple tissue phantom to test its efficacy as an MRI contrast agent. This study demonstrated the potential activity of Gd-chlorin as not only a MRI contrast agent, but also as a PDT photosensitizer by using a simple tissue phantom and conducting a very brief MRI experiment.

Three OOP Haptic Simulator for a Needle Biopsy (3자유도 힘반향 장치를 이용한 침생검 햅틱 시뮬레이터)

  • 권동수;경기욱;감홍식;박현욱;나종범
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.539-539
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    • 2000
  • This paper shows how to implement force reflection for a needle insertion problem. The target is a needle spine biopsy simulator for tumor inspection by needle insertion. Simulated force is calculated from the relationship of volume graphic data and the orientation and Position of the needle, and it is generated using PHANTOM$^{TM}$. To generate realistic force reflection, the directional force of the needle has been generated by tissue model. The other rotational force is generated using a pivot to keep the needle in the initial inserted direction after puncturing the skin. Since the used haptic device has limitation for generating high stiffness and large damping, scale downed model and digital filter are used to stabilize the system.m.

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Measurement of Internal Temperature Distribution for the Evaluation of Focused Ultrasound (FUS) Stimulation Devices (집속초음파 자극기의 성능평가를 위한 팬텀 내부온도 측정)

  • Doh, Il;Joe, Daniel J.;Kim, Sung Mok;Baik, Kyung Min;Kim, Yong Tae;Park, Seung Min
    • Journal of Biomedical Engineering Research
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    • v.43 no.3
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    • pp.147-152
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    • 2022
  • This research is to measure real-time temperature distribution inside a tissue-mimicking phantom for the safety and effectiveness evaluations of focused ultrasound (FUS) device capable of linear scanning stimulation. Since the focusing area of the FUS stimulation device is smaller than diameter of conventional thermal probe and keeps moving, it is impossible to monitor temperature distribution inside the phantom. By using the phantom with a thin film temperature sensor array inserted, real-time temperature change caused by the FUS device was measured. The translation of the measured temperature peak was also tracked successfully. The present phantom had been experimentally proven to be applicable to validate the performance and safety of the therapeutic ultrasound devices.

Therapeutic Proton Beam Range Measurement with EBT3 Film and Comparison with Tool for Particle Simulation

  • Lee, Nuri;Kim, Chankyu;Song, Mi Hee;Lee, Se Byeong
    • Progress in Medical Physics
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    • v.30 no.4
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    • pp.112-119
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    • 2019
  • Purpose: The advantages of ocular proton therapy are that it spares the optic nerve and delivers the minimal dose to normal surrounding tissues. In this study, it developed a solid eye phantom that enabled us to perform quality assurance (QA) to verify the dose and beam range for passive single scattering proton therapy using a single phantom. For this purpose, a new solid eye phantom with a polymethyl-methacrylate (PMMA) wedge was developed using film dosimetry and an ionization chamber. Methods: The typical beam shape used for eye treatment is approximately 3 cm in diameter and the beam range is below 5 cm. Since proton therapy has a problem with beam range uncertainty due to differences in the stopping power of normal tissue, bone, air, etc, the beam range should be confirmed before treatment. A film can be placed on the slope of the phantom to evaluate the Spread-out Bragg Peak based on the water equivalent thickness value of PMMA on the film. In addition, an ionization chamber (Pin-point, PTW 31014) can be inserted into a hole in the phantom to measure the absolute dose. Results: The eye phantom was used for independent patient-specific QA. The differences in the output and beam range between the measurement and the planned treatment were less than 1.5% and 0.1 cm, respectively. Conclusions: An eye phantom was developed and the performance was successfully validated. The phantom can be employed to verify the output and beam range for ocular proton therapy.

Development of a Pelvic Phantom for Dose Verification in High Dose Rate (HDR) Brachytherapy

  • Jang, Ji-Na;Suh, Tae-Suk;Huh, Soon-Nyung;Kim, Hoi-Nam;Yoon, Sei-Chul;Lee, Hyoung-Koo;Choe, Bo-Young
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.150-153
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    • 2002
  • High dose rate (HDR) brachytherapy in the treatment of cervix carcinoma has become popular, because it eliminated many of the problems with conventional brachytherapy. In order to improve clinical effectiveness with HDR brachytherapy, dose calculation algorithm, optimization procedures, and image registrations should be verified by comparing the dose distributions from a planning computer and those from a humanoid phantom irradiated. Therefore, the humanoid phantom should be designed such that the dose distributions could be quantitatively evaluated by utilizing the dosimeters with high spatial resolution. Therefore, the small size of thermoluminescent dosimeter (TLD) chips with the dimension of 1/8" and film dosimetry with spatial resolution of <1mm used to measure the radiation dosages in the phantom. The humanoid phantom called a pelvic phantom is made of water and tissue-equivalent acrylic plates. In order to firmly hold the HDR applicators in the water phantom, the applicators are inserted into the grooves of the applicator supporters. The dose distributions around the applicators, such as Point A and B, can be measured by placing a series of TLD chips (TLD-to- TLD distance: 5mm) in three TLD holders, and placing three verification films in orthogonal planes.

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Evaluation of the reconstruction of image acquired from CT simulator to reduce metal artifact (Metal artifact 감소를 위한 CT simulator 영상 재구성의 유용성 평가)

  • Choi, Ji Hun;Park, Jin Hong;Choi, Byung Don;Won, Hui Su;Chang, Nam Jun;Goo, Jang Hyun;Hong, Joo Wan
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.2
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    • pp.191-197
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    • 2014
  • Purpose : This study presents the usefulness assessment of metal artifact reduction for orthopedic implants(O-MAR) to decrease metal artifacts from materials with high density when acquired CT images. Materials and Methods : By CT simulator, original CT images were acquired from Gammex and Rando phantom and those phantoms inserted with high density materials were scanned for other CT images with metal artifacts and then O-MAR was applied to those images, respectively. To evaluate CT images using Gammex phantom, 5 regions of interest(ROIs) were placed at 5 organs and 3 ROIs were set up at points affected by artifacts. The averages of standard deviation(SD) and CT numbers were compared with a plan using original image. For assessment of variations in dose of tissue around materials with high density, the volume of a cylindrical shape was designed at 3 places in images acquired from Rando phantom by Eclipse. With 6 MV, 7-fields, $15{\time}15cm2$ and 100 cGy per fraction, treatment planning was created and the mean dose were compared with a plan using original image. Results : In the test with the Gammex phantom, CT numbers had a few difference at established points and especially 3 points affected by artifacts had most of the same figures. In the case of O-MAR image, the more reduction in SD appeared at all of 8 points than non O-MAR image. In the test using the Rando Phantom, the variations in dose of tissue around high density materials had a few difference between original CT image and CT image with O-MAR. Conclusion : The CT images using O-MAR were acquired clearly at the boundary of tissue around high density materials and applying O-MAR was useful for correcting CT numbers.