• Title/Summary/Keyword: Tissue Phantom

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ORGAN DOSE, EFFECTIVE DOSE AND RISK ASSESSMENT FROM COMPUTED TOMOGRAPHY TO HEAD AND NECK REGION (두경부 전산화 단층촬영시의 주요 장기선량, 유효선량 및 위험도)

  • Kim Ae-Jj;Cho Bong-Hae;Nah Kyung-Soo
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.25 no.1
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    • pp.27-38
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    • 1995
  • The organ or tissue doses were determined with head and neck phantom measurement for multiple axial scans (36 slices), multiple coronal scans (13 slices), 3 types of single axial scans(orbit, maxillary sinus and mandibular canal) and single coronal scan (maxillary sinus). For each scan sequence 30 TLDs were placed in selected sites(16 internal sites and 14 external sites) in a tissue-equivalent phantom. The exposure was made at 120kVp, 500mAs with 5 mm slice width. The results were as follows : 1. In multiple axial scans, the greatest effective dose recorded was that delivered to the thyroid glands(2.77 mSv) and the least was that received by the skin(0.05 mSv). From these data, stochastic effects were 202.2x10/sup -6/ and 3.7×10/sup -6/, respectively. 2. In multiple coronal scans, the greatest effective dose recorded was that delivered to the salivary glands(0.58 mSv) and the least was that received by the skin(0.01 mSv). From these data, stochastic effects were 42.2×10/sup -6/ and 0.7×10/sup -6/, repectively. 3. Among single axial scans, the greatest effective dose recorded was that delivered to the salivary gland(0.38 mSv) in maxillary sinus scan. From this data, stochastic effect was 27.7×10/sup -6/. 4. In single coronal scan, the greatest effective dose recorded was that delivered to the salivary gland(0.01 mSv). From this data, stochastic effect was 1.0×10/sup -6/. 5. The equivalent dose measured that delivered to the lens of the eyes was 69.64 mSv in multiple axial scan, 39.32 mSv in multiple coronal scan and 36.77 mSv in single axial scan(orbit).

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Secondary Neutron Dose Measurement for Proton Line Scanning Therapy

  • Lee, Chaeyeong;Lee, Sangmin;Chung, Kwangzoo;Han, Youngyih;Chung, Yong Hyun;Kim, Jin Sung
    • Progress in Medical Physics
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    • v.27 no.3
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    • pp.162-168
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    • 2016
  • Proton therapy is increasingly being actively used in the treatment of cancer. In contrast to photons, protons have the potential advantage of delivering higher doses to the cancerous tissue and lower doses to the surrounding normal tissue. However, a range shifter is needed to degrade the beam energy in order to apply the pencil beam scanning technique to tumors located close to the minimum range. The secondary neutrons are produced in the beam path including within the patient's body as a result of nuclear interactions. Therefore, unintended side effects may possibly occur. The research related to the secondary neutrons generated during proton therapy has been presented in a variety of studies worldwide, since 2007. In this study, we measured the magnitude of the secondary neutron dose depending on the location of the detector and the use of a range shifter at the beam nozzle of the proton scanning mode, which was recently installed. In addition, the production of secondary neutrons was measured and estimated as a function of the distance between the isocenter and detector. The neutron dose was measured using WENDI-II (Wide Energy Neutron Detection Instruments) and a Plastic Water phantom; a Zebra dosimeter and 4-cm-thick range shifter were also employed as a phantom. In conclusion, we need to consider the secondary neutron dose at proton scanning facilities to employ the range shifter reasonably and effectively.

The Difference of the Changes of Images on Ultrasound Scanner Setting Parameters

  • Kang, Hae-Kyung;Kim, Youn-Min;Kim, Hyun-Soo;Lee, Sung-Hee;Cho, Se-Youn;Lyu, Young-Eun;Jung, In-A
    • Korean Journal of Digital Imaging in Medicine
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    • v.12 no.2
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    • pp.81-87
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    • 2010
  • The setting parameters of ultrasound scanner give influences to change of image. Sonographers have used a Matlab program to make Low Contrast Sensitivity(LCS) value and compared original images in order to evaluate the use of the supersonic diagnosis machinery. We confirmed the change of image in Grayscale values using Photoshop program. Experiment equipment of our research used A Medison Accuvix V10, A Multi-Tissue Ultrasound Phantom(040 GSE) of CHRIS Company, A Adobe Photoshop CS4 Program, A Convex Probe, A USB memory stick, A Probe Fixation Equipment. The method used Gain, Dynamic Range(DR) of the setting parameters of ultrasound scanner and researched Gain and DR was set to 10 dB. We changed the different settings to see the changes of images using Grayscale values of a Photoshop program about tissue images of a phantom. This study evaluated DR and Gain whether it is an image controller to get the optimum contrast to produce an image to see the how effect on the images. We did not use Gateway in supersonic diagnosis machinery. We can easily open to open the files through Photoshop program before we get Digital Imaging and Communications in Medicine(DICOM) files use USB memory stick in supersonic diagnosis machinery. When we diagnosed the lesion of the patient with ultrasound, the contrast and the Gray scale value of image are very important. In this research, we determined the optimum setting parameters that provided useful information to diagnose disease and evaluated the change of improved images.

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Disign and Thermal Distribution of Intra-hyperthermia Microwave Antennas for Utero-cervical Applicators (자궁강내 온열치료를 위한 마이크로파 안테나의 제작과 온열 분포)

  • Chu, Sung-Sil;Moon, Sun-Rock
    • Radiation Oncology Journal
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    • v.8 no.1
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    • pp.133-136
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    • 1990
  • Intracavitary brachytherapy combined hypertermin for utero-conical cancer seems to be a promising method for salvage treatments in persistent tumors and inoperable or previously irradiated cervical recurrences. In order to heat the vaginal apex and uterus, powerfull conical antennas which are suitable for afterloading cervical applicator have been designed for use in conjuction with intracavitary radiation therapy. The antennas were constructed with conical conductive material to feed line and the effective lenght were designed proportional to microwave length, Power deposition profiles of 2450 MHz of conical antennas were studied in both phantom models and muscle tissue and compared to those of commonly used dipole antenna. Improvement of the heating pattern was found in both phantom and muscle tissue. The heating pattern produced by the conical antenna resembles an ellipsoid and then the temperature distribution in depth was extended to $2\~3\;cm$ from the effective antenna axis.

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SAR Analysis for Test Positions of Mobile Phone (휴대전화의 시험위치에 따른 SAR 분석)

  • 최형도;이애경;조광윤;오학태
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.12 no.7
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    • pp.1199-1205
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    • 2001
  • There has been an increase in the public concern about possible health risks by electromagnetic exposure from mobile phones. Recently, several SAR measurement procedures have been proposed to demonstrate the compliance of mobile phone with safety limits. To determine the maximum localized SAR of a test mobile phone, the electric field distribution is measured in the head phantom with simulated tissue liquid using the probe The important parameters in SAR measurement are the E-field probe, the shape and size of phantom, the electrical parameters of simulated tissue liquid, and test position, etc. Therefore, in order to setup the measurement standard, the studies on these factors are required. In this paper, the effects of the maximum localized SAR on the test positions of mobile phones were analyzed by the numerical computation and the SAR measurement. From the results, the worst condition of commonly used positions was determined and the touch and tilted positions were adopted as test positions of the domestic SAR measurement standard.

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Monte Carlo Investigation of Dose Enhancement due to Gold Nanoparticle in Carbon-12, Helium-4, and Proton Beam Therapy

  • Sang Hee Ahn
    • Progress in Medical Physics
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    • v.33 no.4
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    • pp.114-120
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    • 2022
  • Purpose: Particle beam therapy is advantageous over photon therapy. However, adequately delivering therapeutic doses to tumors near critical organs is difficult. Nanoparticle-aided radiation therapy can be used to alleviate this problem, wherein nanoparticles can passively accumulate at higher concentrations in the tumor tissue compared to the surrounding normal tissue. In this study, we investigate the dose enhancement effect due to gold nanoparticle (GNP) when Carbon-12, He-4, and proton beams are irradiated on GNP. Methods: First, monoenergetic Carbon-12 and He-4 ion beams of energy of 283.33 MeV/u and 150 MeV/u, respectively, and a proton beam of energy of 150 MeV were irradiated on a water phantom of dimensions 30 cm×30 cm×30 cm. Subsequently, the secondary-particle information generated near the Bragg peak was recorded in a phase-space (phsp) file. Second, the obtained phsp file was scaled down to a nanometer scale to irradiate GNP of diameter 50 nm located at the center of a 4 ㎛×4 ㎛×4 ㎛ water phantom. The dose enhancement ratio (DER) was calculated in intervals of 1 nm from the GNP surface. Results: The DER of GNP computed at 1 nm from the GNP surface was 4.70, 4.86, and 4.89 for Carbon-12, He-4, and proton beams, respectively; the DER decreased rapidly with increasing distance from the GNP surface. Conclusions: The results indicated that GNP can be used as radiosensitizers in particle beam therapy. Furthermore, the dose enhancement effect of the GNP absorbed by tumor cells can aid in delivering higher therapeutic doses.

Evaluation of Tissue Inhomogeneity for Gamma-knife Radiosurgery Using Film Dosimetry (감마 나이프 방사선 수술시 필름 선량 측정에 의한 조직 불균일성에 대한 연구)

  • Cho, Heung-Lae;Shon, Seung-Chang;Shu, Hyun-Suk
    • Radiation Oncology Journal
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    • v.16 no.3
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    • pp.325-335
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    • 1998
  • Purpose : Since the mid cranial fossa is composed of various thickness of bone, the tissue inhomogeneity caused by bone would produce dose attenuation in cobalt-60 gamma knife irradiation. The correction factor for bone attenuation of cobalt-60 which is used for gamma knife source is -3.5$\%$. More importantly, nearly all the radiosurgery treatment planning systems assume a treatment volume of unit density: any perturbation due to tissue inhomogeneity is neglected, This study was performed to confirm the bone attenuation in mid cranial fossa using gamma knife. Materials and Methods : Computed tomography was performed after Leksell stereotactic frame had been liked to the Alderson Rando Phantom (human phantom) skull area. Kodak X-omat V film was inserted into two sites of pituitary adenoma point and acoustic neurinoma point, and irradiated by gamma knife with 14mm and 18mm collimator. An automatic scanning densitometer with a 1mm aperture is used to measure the dose profile along the x and y axis. Results : Isodose curve constriction in mid cranial fossa is observed with various ranges. Pituitary tumor point is greater than acoustic neurinoma point (0.2-3.0 mm vs 0.1-1.3 mm) and generally 14 mm collimator is greater than 18mm collimator (0.4-3.0 mm vs. 0.2-2.2 mm) Even though the isodose constriction is found, constriction of 50$\%$ isodose curve which is used for treatment reference line does not exceed 1 mm. This range is too small to influence the treatment planning and treatment results. Conclusion : Radiosurgery planning system of gamma knife does not show significant error to be corrected without consideration of bone attenuation.

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A Study on the Distribution of X-ray according to the Thickness of Soft Tissue in Radiography (X선촬영시(線撮影時) 연부조직(軟部組織) 두께에 따른 선량분포(線量分布)에 관(關)한 연구(硏究))

  • Park, Soung-Ock
    • Journal of radiological science and technology
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    • v.11 no.2
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    • pp.3-15
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    • 1988
  • When X-rays were projected into a patient, there occured the phenomena such as penetration, absorption and scattering etc. The penetrating rays were recorded on films as X-ray image used for diagnosis but scattered rays caused the radiation hazard both to the patient, specialist and technicians. The soft tissue includes many organs which are sensitive to the radiation and in may occupy $40{\sim}50%$ of body weight. Therefore X-rays should be carefully projected to the patient and it is strongly recommended to analyse the distribution of X-rays, when ever the patient is exposed to X-rays. In this study, the distribution of X-ray according to the thickness, the radiation field and the tube voltages (kVp) in soft tissue, the following results were obtained: 1. Total transmitted rays which kept the step with X-ray tube voltage (kVp) increased in proportion to the increasing of X-ray tube voltage. 2. The scattered ray rate in the total transmitted ray was not significantly found with X-ray tube voltage. 3. The affecting factors of the scattered ray rate in total transmitted ray were shown through the radiation field and the thickness. 4. The dose of scattered ray by the angle was observed more in direction of primary ray ($0^{\circ}$) and back scattering ($160^{\circ}$) than in direction of $90^{\circ}$. 5. The more the distance from phantom to the patient should be less distribution of scattered ray.

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The Study of Tissue Dose Perturbation by Air Cavity with 6MV Photon Beam (6MV 광자선에서 공동에 의한 조직 선량변동에 관한 연구)

  • Shin, Byung-Chul;Yoo, Myung-Jin;Moon, Chang-Woo;Jeung, Tae-Sig;Yum, Ha-Yong
    • Radiation Oncology Journal
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    • v.13 no.4
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    • pp.397-402
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    • 1995
  • Purpose : To determine the perturbation effect in the tissue downstream from surface layers of lesions located in the air/tumor-tissue interface of larynx using 6MV photon beam. Materials and Methods : Thermoluminescent dosimeters(TLDs), were embedded at 3 measurement locations in slab no. 7 of a humanoid phantom and exposed to forward and backward direction using various field sizes($4{\times}4cm^2\;-\;15{\times}15cm^2$). Results : At the air/tissue interface, forward dose perturbation factor(FDPF) is about 1.085 with $4{\times}4cm^2,\;1.05\;with\;7{\times}7cm^2,\;1.048\;with\;10{\times}10cm^2$ and $1.041\;with\;15{\times}15cm^2$. Backscatter dose perturbation factor(BDPF) is about 0.99 with $4{\times}4cm^2$, 0.981 with $7{\times}7cm^2$, 0.956 with $10{\times}10cm^2$ and 0.97 with $15{\times}15cm^2$. Conclusion : FDPF is greater as field size is smaller. And FDPF is smaller as the distance is further from the air/tissue interface.

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Efficient Experimental Design for Measuring Magnetic Susceptibility of Arbitrarily Shaped Materials by MRI

  • Hwang, Seon-ha;Lee, Seung-Kyun
    • Investigative Magnetic Resonance Imaging
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    • v.22 no.3
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    • pp.141-149
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    • 2018
  • Purpose: The purpose of this study is to develop a simple method to measure magnetic susceptibility of arbitrarily shaped materials through MR imaging and numerical modeling. Materials and Methods: Our 3D printed phantom consists of a lower compartment filled with a gel (gel part) and an upper compartment for placing a susceptibility object (object part). The $B_0$ maps of the gel with and without the object were reconstructed from phase images obtained in a 3T MRI scanner. Then, their difference was compared with a numerically modeled $B_0$ map based on the geometry of the object, obtained by a separate MRI scan of the object possibly immersed in an MR-visible liquid. The susceptibility of the object was determined by a least-squares fit. Results: A total of 18 solid and liquid samples were tested, with measured susceptibility values in the range of -12.6 to 28.28 ppm. To confirm accuracy of the method, independently obtained reference values were compared with measured susceptibility when possible. The comparison revealed that our method can determine susceptibility within approximately 5%, likely limited by the object shape modeling error. Conclusion: The proposed gel-phantom-based susceptibility measurement may be used to effectively measure magnetic susceptibility of MR-compatible samples with an arbitrary shape, and can enable development of various MR engineering parts as well as test biological tissue specimens.